Latest news with #Alpha1AntitrypsinDeficiency
News.com.au
5 days ago
- Entertainment
- News.com.au
MTV: 16 & Pregnant star announces shock death of her teenage son
16 and Pregnant star Whitney Purvis' son has died at the age of 16. Weston Gosa Jr. died on Monday before his heartbroken mum posted an emotional tribute announcing the news on social media. The devastated mum, 33, said on Facebook: 'This is so hard to write. My beautiful son, Weston has passed away.' Whitney appeared on the MTV show 16 and Pregnant in 2009. She added in her post: 'Life is so cruel and unfair. I just don't understand. 'Oh my baby is gone and I don't know what to do with myself.' She added: 'He was so perfect.' Whitney did not reveal his cause of death. The grieving mum said that she was in disbelief and could not believe that this was happening. She said: 'I love you so much, Weston Owen Gosa. God, I love you so much. 'You are my heart. I was so proud of the young man you were becoming. I just can't go on without you. 'Rest in Peace, my angel. You are gone too soon.' Weston's stepmum Amy Gosa provided some more information of the teenager's tragic passing. She explained that the teen was found at 7am unresponsive, and that she was unable to wake him up. Amy said on Facebook: 'He was not breathing, we attempted CPR and called an ambulance. 'The paramedics attempted it as well and took him to the hospital in Gordon County [Georgia] where he was pronounced dead.' She also noted that the star's child has suffered from 'several health issues', including diabetes. Weston had also been diagnosed with a genetic disorder called Alpha-1 antitrypsin deficiency - which can cause lung and liver damage. But the heartbroken family are still waiting on an autopsy to determine Weston's exact cause of death. Weston was born during the first season of MTV's 16 and Pregnant, to Whitney's boyfriend at the time, Weston Lewis Gosa.
Globe and Mail
12-02-2025
- Business
- Globe and Mail
Alpha-1 Antitrypsin Deficiency Clinical Trials and Studies: EMA, PDMA, FDA Approvals, Mechanism of Action, ROA, NDA, IND, and Companies by DelveInsight
DelveInsight's, ' Alpha 1 Antitrypsin Deficiency Pipeline Insight ' report provides comprehensive insights about 12+ companies and 12+ pipeline drugs in Alpha 1 Antitrypsin Deficiency pipeline landscape. It covers the Alpha 1 Antitrypsin Deficiency pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Alpha 1 Antitrypsin Deficiency therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive Alpha 1 Antitrypsin Deficiency pipeline products in this space. Stay ahead with the latest insights! Download DelveInsight's comprehensive Alpha 1 Antitrypsin Deficiency Pipeline Report to explore emerging therapies, key Alpha 1 Antitrypsin Deficiency Companies, and future Alpha 1 Antitrypsin Deficiency treatment landscapes @ Alpha 1 Antitrypsin Deficiency Pipeline Outlook Report Key Takeaways from the Alpha 1 Antitrypsin Deficiency Pipeline Report In February 2025:- Grifols Therapeutics Inc.:- The purpose of this study is to evaluate the safety and tolerability of 72 milligrams per kilogram (mg/kg) and 180 mg/kg Alpha-1 15%, administered as a single-dose subcutaneous (SC) infusion and subsequently as weekly SC infusions over 8 weeks in participants with Alpha1-Antitrypsin Deficiency (AATD). In January 2025:- Takeda:- The liver produces a protein called alpha-1 antitrypsin (AAT). AAT is normally released into the bloodstream. In some people, the liver makes an abnormal version of the AAT protein, called Z-AAT. Making an abnormal version of the AAT protein can result in liver disease as Z-AAT builds up in liver cells, which leads to liver problems such as liver scarring (fibrosis), continuing liver damage (cirrhosis), and eventually endstage liver disease. In January 2025:- Korro Bio Inc.:- The purpose of this first-in human (FIH) study is to assess the safety, tolerability, and pharmacokinetics (PK) of single and multiple doses of KRRO-110 in both healthy adult participants and in clinically stable patients with Alpha-1 antitrypsin deficiency (AATD). In January 2025:- Arrowhead Pharmaceuticals: - The purpose of AROAAT2001 (SEQUOIA) is to evaluate the safety, efficacy and tolerability of multiple doses of the investigational product, Fazirsiran Injection, administered subcutaneously to participants with alpha-1 antitrypsin deficiency (AATD). In January 2025:- Kamada Ltd:- The goal of this clinical trial is to learn if AAT for inhalation, at a dose of 80 mg/day can slow the progression of lung disease in people who have lung disease caused by severe genetic deficiency in Alpha 1 Antitrypsin (AATD). DelveInsight's Alpha 1 Antitrypsin Deficiency pipeline report depicts a robust space with 12+ active players working to develop 12+ pipeline therapies for Alpha 1 Antitrypsin Deficiency treatment. The leading Alpha 1 Antitrypsin Deficiency Companies such as Octapharma, Dicerna Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Vertex Pharmaceuticals, AstraZeneca, Kamada Ltd and others. Promising Alpha-1 Antitrypsin Deficiency Pipeline Therapies such as Fazirsiran Injection, Aerosolized, Recombinant Alpha 1-Antitrypsin, INBRX-101/rhAAT-Fc, ADVM-043, and others. Discover how the Alpha 1 Antitrypsin Deficiency treatment paradigm is evolving. Access DelveInsight's in-depth Alpha 1 Antitrypsin Deficiency Pipeline Analysis for a closer look at promising breakthroughs @ Alpha 1 Antitrypsin Deficiency Clinical Trials and Studies Alpha 1 Antitrypsin Deficiency Emerging Drugs Profile ARO AAT: Arrowhead Pharmaceuticals ARO AAT is a second generation, N-Acetylgalactosamine (GalNAc) based, subcutaneously administered RNA interference based therapeutic. ARO-AAT is designed to knock down the hepatic production of the mutant alpha-1 antitrypsin (Z-AAT) protein, the cause of progressive liver disease in AATD patients. In June 2019, the US FDA has granted Fast Track designation to ARO-AAT. ARO-AAT is in Phase III clinical studies for the treatment of liver disease associated with alpha-1 antitrypsin deficiency (AATD). ALN-AAT02: Alnylam Pharmaceuticals ALN AAT02 is a subcutaneously administered RNAi therapeutic that targets alpha-1 antitrypsin (AAT). ALN-AAT02 is based on the Alnylam's enhanced stabilization chemistry plus (ESC+)-GalNAc-conjugate technology, which enables subsequent subcutaneous dosing with increased selectivity and a wide therapeutic index. The drug is currently in Phase I/II clinical development for the treatment of ZZ Type AAT Deficiency Liver Disease. The Alpha 1 Antitrypsin Deficiency pipeline report provides insights into The report provides detailed insights about companies that are developing therapies for the treatment of Alpha 1 Antitrypsin Deficiency with aggregate therapies developed by each company for the same. It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Alpha 1 Antitrypsin Deficiency Treatment. Alpha 1 Antitrypsin Deficiency Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects. Alpha 1 Antitrypsin Deficiency Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Alpha 1 Antitrypsin Deficiency market. Get a detailed analysis of the latest innovations in the Alpha 1 Antitrypsin Deficiency pipeline. Explore DelveInsight's expert-driven report today! @ Alpha 1 Antitrypsin Deficiency Unmet Needs Alpha 1 Antitrypsin Deficiency Companies Octapharma, Dicerna Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Vertex Pharmaceuticals, AstraZeneca, Kamada Ltd and others. Alpha 1 Antitrypsin Deficiency pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as Intra-articular Intraocular Intrathecal Intravenous Ophthalmic Oral Parenteral Subcutaneous Topical Transdermal Alpha 1 Antitrypsin Deficiency Products have been categorized under various Molecule types such as Oligonucleotide Peptide Small molecule Download DelveInsight's latest report to gain strategic insights into upcoming Alpha 1 Antitrypsin Deficiency Therapies and key Alpha 1 Antitrypsin Deficiency Developments @ Alpha 1 Antitrypsin Deficiency Market Drivers and Barriers, and Future Perspectives Scope of the Alpha 1 Antitrypsin Deficiency Pipeline Report Coverage- Global Alpha 1 Antitrypsin Deficiency Companies- Octapharma, Dicerna Pharmaceuticals, Alnylam Pharmaceuticals, Arrowhead Pharmaceuticals, Vertex Pharmaceuticals, AstraZeneca, Kamada Ltd and others. Alpha-1 Antitrypsin Deficiency Pipeline Therapies - Fazirsiran Injection, Aerosolized, Recombinant Alpha 1-Antitrypsin, INBRX-101/rhAAT-Fc, ADVM-043, and others. Alpha 1 Antitrypsin Deficiency Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination Alpha 1 Antitrypsin Deficiency Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III Which companies are leading the race in Alpha 1 Antitrypsin Deficiency drug development? Find out in DelveInsight's exclusive Alpha 1 Antitrypsin Deficiency Pipeline Report—access it now! @ Alpha 1 Antitrypsin Deficiency Emerging Drugs and Major Companies Table of Content Introduction Alpha-1 Antitrypsin Deficiency Executive Summary Alpha-1 Antitrypsin Deficiency: Overview Alpha-1 Antitrypsin Deficiency Pipeline Therapeutics Alpha-1 Antitrypsin Deficiency Pipeline Therapeutic Assessment Alpha-1 Antitrypsin Deficiency– DelveInsight's Analytical Perspective Late Stage Products (Phase III) ARO AAT: Arrowhead Pharmaceuticals Drug profiles in the detailed report….. Mid Stage Products (Phase II) Drug Name: Company Name Drug profiles in the detailed report….. Early Stage Products (Phase I/II) ALN-AAT02: Alnylam Pharmaceuticals Drug profiles in the detailed report….. Preclinical and Discovery Stage Products Drug Name: Company Name Drug profiles in the detailed report….. Inactive Products Alpha-1 Antitrypsin Deficiency Key Companies Alpha-1 Antitrypsin Deficiency Key Products Alpha-1 Antitrypsin Deficiency- Unmet Needs Alpha-1 Antitrypsin Deficiency- Market Drivers and Barriers Alpha-1 Antitrypsin Deficiency- Future Perspectives and Conclusion Alpha-1 Antitrypsin Deficiency Analyst Views Alpha-1 Antitrypsin Deficiency Key Companies Appendix About Us DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Yash Bhardwaj Email: Send Email Phone: 9650213330 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: Nevada Country: United States Website:
