Latest news with #Avidity
Yahoo
06-08-2025
- Business
- Yahoo
Avidity Biosciences stock soars on Novartis takeover approach report
-- Avidity Biosciences (NASDAQ:RNA) stock surged 18% Wednesday after the Financial Times reported that Swiss pharmaceutical giant Novartis (NYSE:NVS) has approached the rare disease-focused biotech company about a potential takeover. According to the report, which cited unidentified people familiar with the matter, Novartis has been evaluating a bid for Avidity and expressed interest in an acquisition in recent weeks. Avidity is reportedly working with advisers to assess its options. The discussions are said to be at an early stage, and there is no guarantee that a deal will materialize, according to the sources cited in the report. The news also lifted shares of Dyne Therapeutics (NASDAQ:DYN), a company operating in a similar space, which also jumped 18% on Wednesday. Novartis has been actively reshaping its portfolio in recent years, focusing on high-growth areas including rare diseases. Any potential acquisition of Avidity would align with this strategy, potentially strengthening Novartis's position in the rare disease treatment market. Related articles Avidity Biosciences stock soars on Novartis takeover approach report Apollo economist warns: AI bubble now bigger than 1990s tech mania If Powell goes, does Fed trust go with him? Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
06-08-2025
- Business
Danny McCarthy remis en liberté sous conditions
(Reuters) -Swiss drugmaker Novartis has approached U.S. biotech Avidity Biosciences for a potential takeover offer, the Financial Times reported on Wednesday, citing people familiar with the matter. Shares of Avidity rose 23% to $47.1. It has a market value of $4.6 billion, according to LSEG data. Novartis has been evaluating a bid for Avidity and expressed interest in an acquisition in recent weeks, the report said, in a move aimed at boosting the drugmaker's pipeline of medicines targeting rare genetic disorders. The discussions were at an early stage, the report said, adding that the sources had cautioned that another suitor could emerge or talks could collapse. Avidity, which has been developing treatments for rare muscle disorders, is working with advisers to assess options, the people added. Novartis and Avidity declined to comment when contacted by Reuters. Del-zota, Avidity's lead drug, is in early to mid-stage development as a potential treatment for a rare form of Duchenne muscular dystrophy. The company is also working on two other drugs for serious muscle diseases. Novartis has been actively striking deals in 2025 as it looks to bolster its drug pipeline and drive future growth. In February, Novartis agreed to acquire Anthos Therapeutics for $3.1 billion to enhance its cardiovascular portfolio. The company also struck a deal in April valued at up to $1.7 billion to acquire Regulus Therapeutics, gaining access to an experimental treatment for a serious kidney disease. Additionally, last month Novartis partnered with Matchpoint Therapeutics in a deal worth up to $1 billion to develop oral medicines targeting several inflammatory conditions. (Reporting by Padmanabhan Ananthan in Bengaluru; Editing by Arun Koyyur and Shailesh Kuber)
Yahoo
06-08-2025
- Business
- Yahoo
Novartis weighs deal for biotech Avidity Biosciences, FT reports
(Reuters) -Swiss drugmaker Novartis has approached U.S. biotech Avidity Biosciences for a potential takeover offer, the Financial Times reported on Wednesday, citing people familiar with the matter. Shares of Avidity rose 23% to $47.1. It has a market value of $4.6 billion, according to LSEG data. Novartis has been evaluating a bid for Avidity and expressed interest in an acquisition in recent weeks, the report said, in a move aimed at boosting the drugmaker's pipeline of medicines targeting rare genetic disorders. The discussions were at an early stage, the report said, adding that the sources had cautioned that another suitor could emerge or talks could collapse. Avidity, which has been developing treatments for rare muscle disorders, is working with advisers to assess options, the people added. Novartis and Avidity declined to comment when contacted by Reuters. Del-zota, Avidity's lead drug, is in early to mid-stage development as a potential treatment for a rare form of Duchenne muscular dystrophy. The company is also working on two other drugs for serious muscle diseases. Novartis has been actively striking deals in 2025 as it looks to bolster its drug pipeline and drive future growth. In February, Novartis agreed to acquire Anthos Therapeutics for $3.1 billion to enhance its cardiovascular portfolio. The company also struck a deal in April valued at up to $1.7 billion to acquire Regulus Therapeutics, gaining access to an experimental treatment for a serious kidney disease. Additionally, last month Novartis partnered with Matchpoint Therapeutics in a deal worth up to $1 billion to develop oral medicines targeting several inflammatory conditions. Sign in to access your portfolio
Yahoo
11-06-2025
- Business
- Yahoo
Avidity Biosciences to Present Topline Data from Phase 1/2 FORTITUDE™ Trial of Del-brax in People Living with Facioscapulohumeral Muscular Dystrophy at 32nd Annual FSHD Society International Research Congress
-- FDA alignment on accelerated and full approval pathways for delpacibart braxlosiran (del-brax) in facioscapulohumeral muscular dystrophy (FSHD) -- -- Jeffrey M. Statland, M.D., Professor of Neurology, University of Kansas Medical Center, and FORTITUDE trial investigator, will present topline del-brax data from dose escalation cohorts in oral presentation -- -- Stephen Tapscott, M.D., Ph.D., Professor of Human Biology and Clinical Research, Fred Hutchinson Cancer Center, will highlight results on the characterization of a novel DUX4-regulated circulating biomarker in oral and poster presentations -- SAN DIEGO, June 11, 2025 /PRNewswire/ -- Avidity Biosciences, Inc. (Nasdaq: RNA), a biopharmaceutical company committed to delivering a new class of RNA therapeutics called Antibody Oligonucleotide Conjugates (AOCs™) to profoundly improve people's lives, today announced that the company will be presenting two oral and one poster presentations at the 32nd Annual FSHD Society International Research Congress, being held June 12-13, 2025, in Amsterdam, the Netherlands. Earlier this week, Avidity announced FDA alignment on accelerated and full approval pathways for delpacibart braxlosiran (del-brax) in facioscapulohumeral muscular dystrophy (FSHD). 32nd Annual FSHD Society International Research Congress Presentations Topline Data from Dose Escalation Cohorts A and B in FORTITUDE™, a Phase 1/2 Trial Evaluating Del-brax (delpacibart braxlosiran) in Adults with Facioscapulohumeral Muscular Dystrophy (FSHD) Oral presentation: Jeffrey M. Statland, M.D., to present June 13, 2025, from 5:20 - 5:40 p.m. Central European Summer Time (CEST) / 11:20 - 11:40 a.m. ET Characterization of a promising DUX4-regulated circulating biomarker for facioscapulohumeral dystrophy (FSHD) Oral presentation: Stephen Tapscott, M.D., Ph.D., Professor of Human Biology and Clinical Research, Fred Hutchinson Cancer Center, to present on June 12, 2025, from 6:25 - 6:30 p.m. CEST / 12:25 - 12:30 p.m. ET Poster presentation (#7.08): June 12, 2025, from 7:15 - 8:00 p.m. CEST / 1:15 - 2:00 p.m. ET The presentations and poster are available on the publications page of Avidity's website at About AvidityAvidity Biosciences, Inc.'s mission is to profoundly improve people's lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs™). Avidity is revolutionizing the field of RNA with its proprietary AOCs, which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. Utilizing its proprietary AOC platform, Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare neuromuscular diseases: myotonic dystrophy type 1 (DM1), Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is also advancing two wholly-owned precision cardiology development candidates addressing rare genetic cardiomyopathies. In addition, Avidity is broadening the reach of AOCs with its advancing and expanding pipeline including programs in cardiology and immunology through key partnerships. Avidity is headquartered in San Diego, CA. For more information about our AOC platform, clinical development pipeline and people, please visit and engage with us on LinkedIn and X. Forward-Looking StatementsAvidity cautions readers that statements contained in this press release regarding matters that are not historical facts are forward-looking statements. These statements are based on the company's current beliefs and expectations. Such forward-looking statements include, but are not limited to, statements regarding: Avidity's plans to present topline data from the dose escalation cohorts of the Phase 1/2 FORTITUDE™ trial; the status and availability of accelerated and full approval pathways for del-brax and Avidity's planned participation at the 32nd Annual FSHD Society International Research Congress and the contents of its scheduled presentations. The inclusion of forward-looking statements should not be regarded as a representation by Avidity that any of these plans will be achieved. Actual results may differ from those set forth in this press release due to the risks and uncertainties inherent in Avidity's business and beyond its control, including, without limitation, the data and results produced from the clinical study of del-brax may not support BLA submission or accelerated or full approval, and may not be satisfactory to the FDA and other regulators; later developments with the FDA and other regulators may be inconsistent with the feedback received as of the date hereof; and the risks described in Avidity's Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and subsequent filings with the SEC. Avidity cautions readers not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and the company undertakes no obligation to update such statements to reflect events that occur or circumstances that arise after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Investor Contact:Kat Lange(619) 837-5014investors@ Media Contact:Kristina Coppola (619) 837-5016media@ View original content to download multimedia: SOURCE Avidity Biosciences, Inc. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Business Insider
11-06-2025
- Business
- Business Insider
Avidity Biosciences initiated with a Strong Buy at Raymond James
Raymond James initiated coverage of Avidity Biosciences (RNA) with a Strong Buy rating and $65 price target as part of a broader research note on selection Biotech names. Risk/reward skews favorably across the sector, though while companies with high PoS – probability of success – lead assets allow for higher conviction, highly attractive skews on less de-risked assets may deliver the most outsized returns, the analyst tells investors in a research note. For the company, the firm cites its high conviction in del-zota becoming the first approved drug from Avidity's antibody oligonucleotide conjugate – AOC – platform, Raymond James added. Confident Investing Starts Here:
