Latest news with #BrainCancerCanada


Hamilton Spectator
21-05-2025
- Health
- Hamilton Spectator
Brain Cancer Canada Awards $68,000 Research Grant for Clinical Trial of Anti-Cancer Vaccine Targeting DIPG, the Most Aggressive Pediatric Brain Cancer
TORONTO, May 17, 2025 (GLOBE NEWSWIRE) — Today, on DIPG Awareness Day, Brain Cancer Canada is pleased to award $68,000 for an innovative research initiative led by Dr. Aru Narendran, MD, PhD, and Dr. Patrick Sipila, PhD, at The University of Calgary and Alberta Children's Hospital. The project, 'Biological Correlative Studies to Improve Current Outcomes of Diffuse Intrinsic Pontine Glioma (DIPG) and High-Risk Brain Tumours with a Neoantigen-Based Anti-Cancer Vaccine in Clinical Trial,' focuses on advancing a novel immunotherapy approach for some of the most aggressive childhood brain cancers. DIPG is a devastating pediatric brain tumour, with fewer than 10% of children surviving two years post-diagnosis. As DIPG progresses, it severely impacts essential brain functions, making it increasingly difficult for children to see, walk, and even breathe. Current treatment options, including radiation therapy and chemotherapy, offer only temporary or limited benefit, and survival rates have remained largely unchanged for decades, despite broader advances in cancer research. In response to this urgent need, Dr. Narendran and Dr. Sipila's team are investigating a new anti-cancer vaccine designed to train a patient's immune system to recognize and eliminate tumour cells. Their research aims to validate the safety, activity, and potential clinical applications of this neoantigen-based immunotherapy. By providing critical biological insights into the vaccine's effectiveness, the project seeks to accelerate the development of promising new treatment options for children affected by DIPG and other high-risk brain tumours. Dr. Narendran explains, 'Every advancement in DIPG research brings renewed hope for the entire brain cancer community. By discovering new and effective treatments, we aim to prove that even the toughest human challenges can be overcome through compassion, collaboration, and innovation. The progress we make today paves the way for tomorrow's cures, where no child's future is cut short by a brain cancer.' This groundbreaking work represents an important step toward improving survival outcomes and offering renewed hope to families impacted by these devastating diagnoses. Brain Cancer Canada acknowledges the tremendous contributions of grassroots fundraisers including Trinity's Army, the $9 Challenge, and Dr. Surya's 8th Charity Raffle that have made this award possible. Immensely grateful for the support, Dr. Narendran explains the critical need for funding, 'Philanthropic organizations such as the Brain Cancer Canada give true hope for children fighting brain cancer, granting the crucial support needed to advance translational research and the preparation of innovative treatment protocols for the future. By funding collaborative efforts and high-risk, high-reward projects, your giving ensures that scientists and physicians continue to work to discover safer, more effective novel treatments for our patients.' In recognition of DIPG Day, Brain Cancer Canada is proud to have The Peace Bridge connecting Canada and the U.S., Cabot Tower on Signal Hill in St. John's, NL, and the CN Tower Toronto, ON, illuminated in yellow. The lighting serves as a powerful symbol of awareness and solidarity in the fight against DIPG. This announcement is part of a series of six grants announced during Brain Cancer Awareness Month. Brain Cancer Canada remains committed to driving forward innovative solutions and pursuing hope for those affected by brain cancer by investing in critically needed research. About Brain Cancer Canada Brain Cancer Canada is a national charity dedicated to improving the lives of those affected by primary malignant brain tumours by funding research, advocating for effective treatment options, and investing in neurosurgical technologies. Since 2015, Brain Cancer Canada has directed more than 2.4 million dollars to brain cancer research, to 25 projects at nine institutions, research centres, and hospitals across Canada. More Information For more detail about this and other research initiatives supported by Brain Cancer Canada, please visit Media Contact: angela@ 1-855-375-1381
Yahoo
21-05-2025
- Health
- Yahoo
Brain Cancer Canada Awards $68,000 Research Grant for Clinical Trial of Anti-Cancer Vaccine Targeting DIPG, the Most Aggressive Pediatric Brain Cancer
TORONTO, May 17, 2025 (GLOBE NEWSWIRE) -- Today, on DIPG Awareness Day, Brain Cancer Canada is pleased to award $68,000 for an innovative research initiative led by Dr. Aru Narendran, MD, PhD, and Dr. Patrick Sipila, PhD, at The University of Calgary and Alberta Children's Hospital. The project, "Biological Correlative Studies to Improve Current Outcomes of Diffuse Intrinsic Pontine Glioma (DIPG) and High-Risk Brain Tumours with a Neoantigen-Based Anti-Cancer Vaccine in Clinical Trial," focuses on advancing a novel immunotherapy approach for some of the most aggressive childhood brain cancers. DIPG is a devastating pediatric brain tumour, with fewer than 10% of children surviving two years post-diagnosis. As DIPG progresses, it severely impacts essential brain functions, making it increasingly difficult for children to see, walk, and even breathe. Current treatment options, including radiation therapy and chemotherapy, offer only temporary or limited benefit, and survival rates have remained largely unchanged for decades, despite broader advances in cancer research. In response to this urgent need, Dr. Narendran and Dr. Sipila's team are investigating a new anti-cancer vaccine designed to train a patient's immune system to recognize and eliminate tumour cells. Their research aims to validate the safety, activity, and potential clinical applications of this neoantigen-based immunotherapy. By providing critical biological insights into the vaccine's effectiveness, the project seeks to accelerate the development of promising new treatment options for children affected by DIPG and other high-risk brain tumours. Dr. Narendran explains, 'Every advancement in DIPG research brings renewed hope for the entire brain cancer community. By discovering new and effective treatments, we aim to prove that even the toughest human challenges can be overcome through compassion, collaboration, and innovation. The progress we make today paves the way for tomorrow's cures, where no child's future is cut short by a brain cancer.' This groundbreaking work represents an important step toward improving survival outcomes and offering renewed hope to families impacted by these devastating diagnoses. Brain Cancer Canada acknowledges the tremendous contributions of grassroots fundraisers including Trinity's Army, the $9 Challenge, and Dr. Surya's 8th Charity Raffle that have made this award possible. Immensely grateful for the support, Dr. Narendran explains the critical need for funding, 'Philanthropic organizations such as the Brain Cancer Canada give true hope for children fighting brain cancer, granting the crucial support needed to advance translational research and the preparation of innovative treatment protocols for the future. By funding collaborative efforts and high-risk, high-reward projects, your giving ensures that scientists and physicians continue to work to discover safer, more effective novel treatments for our patients.' In recognition of DIPG Day, Brain Cancer Canada is proud to have The Peace Bridge connecting Canada and the U.S., Cabot Tower on Signal Hill in St. John's, NL, and the CN Tower Toronto, ON, illuminated in yellow. The lighting serves as a powerful symbol of awareness and solidarity in the fight against DIPG. This announcement is part of a series of six grants announced during Brain Cancer Awareness Month. Brain Cancer Canada remains committed to driving forward innovative solutions and pursuing hope for those affected by brain cancer by investing in critically needed research. About Brain Cancer CanadaBrain Cancer Canada is a national charity dedicated to improving the lives of those affected by primary malignant brain tumours by funding research, advocating for effective treatment options, and investing in neurosurgical technologies. Since 2015, Brain Cancer Canada has directed more than 2.4 million dollars to brain cancer research, to 25 projects at nine institutions, research centres, and hospitals across Canada. More Information For more detail about this and other research initiatives supported by Brain Cancer Canada, please visit Media Contact:angela@
Yahoo
17-05-2025
- Health
- Yahoo
Brain Cancer Canada Awards $68,000 Research Grant for Clinical Trial of Anti-Cancer Vaccine Targeting DIPG, the Most Aggressive Pediatric Brain Cancer
TORONTO, May 17, 2025 (GLOBE NEWSWIRE) -- Today, on DIPG Awareness Day, Brain Cancer Canada is pleased to award $68,000 for an innovative research initiative led by Dr. Aru Narendran, MD, PhD, and Dr. Patrick Sipila, PhD, at The University of Calgary and Alberta Children's Hospital. The project, "Biological Correlative Studies to Improve Current Outcomes of Diffuse Intrinsic Pontine Glioma (DIPG) and High-Risk Brain Tumours with a Neoantigen-Based Anti-Cancer Vaccine in Clinical Trial," focuses on advancing a novel immunotherapy approach for some of the most aggressive childhood brain cancers. DIPG is a devastating pediatric brain tumour, with fewer than 10% of children surviving two years post-diagnosis. As DIPG progresses, it severely impacts essential brain functions, making it increasingly difficult for children to see, walk, and even breathe. Current treatment options, including radiation therapy and chemotherapy, offer only temporary or limited benefit, and survival rates have remained largely unchanged for decades, despite broader advances in cancer research. In response to this urgent need, Dr. Narendran and Dr. Sipila's team are investigating a new anti-cancer vaccine designed to train a patient's immune system to recognize and eliminate tumour cells. Their research aims to validate the safety, activity, and potential clinical applications of this neoantigen-based immunotherapy. By providing critical biological insights into the vaccine's effectiveness, the project seeks to accelerate the development of promising new treatment options for children affected by DIPG and other high-risk brain tumours. Dr. Narendran explains, 'Every advancement in DIPG research brings renewed hope for the entire brain cancer community. By discovering new and effective treatments, we aim to prove that even the toughest human challenges can be overcome through compassion, collaboration, and innovation. The progress we make today paves the way for tomorrow's cures, where no child's future is cut short by a brain cancer.' This groundbreaking work represents an important step toward improving survival outcomes and offering renewed hope to families impacted by these devastating diagnoses. Brain Cancer Canada acknowledges the tremendous contributions of grassroots fundraisers including Trinity's Army, the $9 Challenge, and Dr. Surya's 8th Charity Raffle that have made this award possible. Immensely grateful for the support, Dr. Narendran explains the critical need for funding, 'Philanthropic organizations such as the Brain Cancer Canada give true hope for children fighting brain cancer, granting the crucial support needed to advance translational research and the preparation of innovative treatment protocols for the future. By funding collaborative efforts and high-risk, high-reward projects, your giving ensures that scientists and physicians continue to work to discover safer, more effective novel treatments for our patients.' In recognition of DIPG Day, Brain Cancer Canada is proud to have The Peace Bridge connecting Canada and the U.S., Cabot Tower on Signal Hill in St. John's, NL, and the CN Tower Toronto, ON, illuminated in yellow. The lighting serves as a powerful symbol of awareness and solidarity in the fight against DIPG. This announcement is part of a series of six grants announced during Brain Cancer Awareness Month. Brain Cancer Canada remains committed to driving forward innovative solutions and pursuing hope for those affected by brain cancer by investing in critically needed research. About Brain Cancer CanadaBrain Cancer Canada is a national charity dedicated to improving the lives of those affected by primary malignant brain tumours by funding research, advocating for effective treatment options, and investing in neurosurgical technologies. Since 2015, Brain Cancer Canada has directed more than 2.4 million dollars to brain cancer research, to 25 projects at nine institutions, research centres, and hospitals across Canada. More Information For more detail about this and other research initiatives supported by Brain Cancer Canada, please visit Media Contact:angela@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Ottawa Citizen
14-05-2025
- Health
- Ottawa Citizen
The Dwayne Andrews Glioblastoma Research Grant Awarded to Dr. Jeremy Brown, Dalhousie University
Article content TORONTO, May 14, 2025 (GLOBE NEWSWIRE) — Brain Cancer Canada is proud to announce The Dwayne Andrews Glioblastoma Research Grant of $85,000 awarded to Dr. Jeremy Brown at Dalhousie University for his project, 'Clinical Testing of a High-Resolution Ultrasound Endoscope for Guiding Brain Tumour Resection.' This innovative initiative aims to improve surgical outcomes for patients diagnosed with glioblastoma multiforme (GBM), one of the most aggressive and fatal brain cancers. Article content Article content Article content GBM carries a one-year survival rate of just 25%, and surgical resection remains the primary standard of care. Studies have consistently shown that more accurate tumour removal during surgery is associated with longer patient survival. However, imaging technologies currently available to guide surgeons during operations are limited in both precision and practicality. Article content To address this critical need, Dr. Brown's team has developed a miniature, pencil-sized ultrasound imaging probe capable of visualizing tumour tissue in real time during surgery. This device is distinguished not only by its compact size but also by its exceptionally high resolution, allowing it to detect tumour margins with remarkable accuracy. The project will clinically test the performance of this new technology by evaluating its ability to enhance tumour resection during brain surgery. Article content 'Our goal is to make precision ultrasound imaging during neurosurgery a clinical standard. By increasing the accuracy of brain tumour resection, we can extended survival and improve quality of life for those battling glioblastoma,' says Dr. Brown. 'This generous funding from Brain Cancer Canada represents a crucial step forward in our mission to significantly improve outcomes for patients facing this aggressive form of brain cancer.' Article content Article content The Dwayne Andrews Glioblastoma Research Grant has been made possible through the generous support of the Auto|One Group and The Andrews Family. Article content Kevin Andrews, President & CEO of Auto|One Group, experienced the loss of his brother Dwayne Andrews to Glioblastoma in 2020, less than two years after his diagnosis. 'It is both a personal honour and a privilege on behalf of Auto|One Group to partner with BCC in supporting cutting-edge brain cancer research in memory of my brother,' says Kevin. 'Dwayne's strength and spirit continue to inspire me every day. Collaborating with Dr. Brown at Dalhousie University, our family's alma mater, holds deep meaning for us. This vital research represents hope and is paving the way for innovative treatment options for families impacted by this devastating disease: Everyone deserves the chance for survival — a chance my brother never had.' Article content This announcement is part of a series of six grants announced during Brain Cancer Awareness Month. Brain Cancer Canada remains committed to driving forward innovative solutions and pursuing hope for those affected by brain cancer by investing in critically needed research.


Hamilton Spectator
14-05-2025
- Health
- Hamilton Spectator
The Dwayne Andrews Glioblastoma Research Grant Awarded to Dr. Jeremy Brown, Dalhousie University
TORONTO, May 14, 2025 (GLOBE NEWSWIRE) — Brain Cancer Canada is proud to announce The Dwayne Andrews Glioblastoma Research Grant of $85,000 awarded to Dr. Jeremy Brown at Dalhousie University for his project, 'Clinical Testing of a High-Resolution Ultrasound Endoscope for Guiding Brain Tumour Resection.' This innovative initiative aims to improve surgical outcomes for patients diagnosed with glioblastoma multiforme (GBM), one of the most aggressive and fatal brain cancers. GBM carries a one-year survival rate of just 25%, and surgical resection remains the primary standard of care. Studies have consistently shown that more accurate tumour removal during surgery is associated with longer patient survival. However, imaging technologies currently available to guide surgeons during operations are limited in both precision and practicality. To address this critical need, Dr. Brown's team has developed a miniature, pencil-sized ultrasound imaging probe capable of visualizing tumour tissue in real time during surgery. This device is distinguished not only by its compact size but also by its exceptionally high resolution, allowing it to detect tumour margins with remarkable accuracy. The project will clinically test the performance of this new technology by evaluating its ability to enhance tumour resection during brain surgery. 'Our goal is to make precision ultrasound imaging during neurosurgery a clinical standard. By increasing the accuracy of brain tumour resection, we can extended survival and improve quality of life for those battling glioblastoma,' says Dr. Brown. 'This generous funding from Brain Cancer Canada represents a crucial step forward in our mission to significantly improve outcomes for patients facing this aggressive form of brain cancer.' The Dwayne Andrews Glioblastoma Research Grant has been made possible through the generous support of the Auto|One Group and The Andrews Family. Kevin Andrews, President & CEO of Auto|One Group, experienced the loss of his brother Dwayne Andrews to Glioblastoma in 2020, less than two years after his diagnosis. 'It is both a personal honour and a privilege on behalf of Auto|One Group to partner with BCC in supporting cutting-edge brain cancer research in memory of my brother,' says Kevin . 'Dwayne's strength and spirit continue to inspire me every day. Collaborating with Dr. Brown at Dalhousie University, our family's alma mater, holds deep meaning for us. This vital research represents hope and is paving the way for innovative treatment options for families impacted by this devastating disease: Everyone deserves the chance for survival — a chance my brother never had.' This announcement is part of a series of six grants announced during Brain Cancer Awareness Month. Brain Cancer Canada remains committed to driving forward innovative solutions and pursuing hope for those affected by brain cancer by investing in critically needed research. About Brain Cancer Canada Brain Cancer Canada is a national charity dedicated to improving the lives of those affected by primary malignant brain tumors by funding research, advocating for effective treatment options, and investing in neurosurgical technologies. Since 2015, Brain Cancer Canada has directed more than 2.4 million dollars to brain cancer research, to 25 projects at nine institutions, research centres, and hospitals across Canada. More Information For more detail about this and other research initiatives supported by Brain Cancer Canada, please visit Media Contact: angela@ 1-855-375-1381