Latest news with #Brake
Time Business News
6 days ago
- Automotive
- Time Business News
KRRASS Launches MB8-110T3200 CNC Press Brake—The Ultimate Solution for High-Quality, Cost-Effective Sheet Metal
KRRASS, a leading CNC Press Brake manufacturer and direct supplier, is proud to launch its latest CNC Press Brake, which is equipped with an original DELEM DA53TX controller and a German imported Rexroth valve group. This affordable CNC Press Brake is precise, sensitive, durable, and versatile, suitable for a variety of applications. Its space-saving design makes it ideal for start-ups and small businesses. In the vast world of the metalworking industry, CNC Press Brake is a key equipment for achieving precise sheet metal forming, and its performance is directly related to the company's production efficiency and product quality. The MB8-110T/3200 CNC Press Brake, with its unique design and excellent performance, is gradually becoming the favorite of many companies and emerging in the market. Unmatched Power and Capacity A significant highlight of the MB8-110T/3200 CNC Press Brake is its powerful bending force. The nominal force of 110 tons enables it to easily handle metal sheets of various thicknesses and materials. Whether it is common ordinary carbon steel, stainless steel with higher hardness, or aluminum alloy with softer texture, this CNC Press Brake can accurately bend the sheet to the required angle with stable and strong pressure output. In practical applications, for metal sheets with a certain thickness range, it can complete the bending task with excellent performance to meet the diverse processing needs of enterprises. The working length of the CNC Press Brake reaches 3200 mm. This size advantage makes it easy to handle large workpieces. In some building decoration material manufacturers, large-format metal sheets are often required to be bent for the production of ceiling curtain walls, large door and window frames and other products. The long workbench and large working stroke of the MB8-110T/3200 CNC Press Brake can ensure that these large plates are fully supported and accurately bent during the processing process, effectively avoiding the processing problems caused by insufficient workbench size or limited stroke, and greatly improving production efficiency and product quality. Precision Engineering and Durable Design In terms of structural design, the MB8-110T/3200 CNC Press Brake adopts an all-steel integral welded structure and eliminates internal stress through advanced processes. This carefully crafted structure gives the machine tool extremely high overall precision and excellent rigidity. In actual work, it can effectively resist the distortion and tilt caused by the bending force, ensuring that the equipment can still maintain stable operation and consistent processing accuracy under long-term and high-intensity working conditions. Even in the face of complex bending processes and high-intensity production tasks, the CNC Press Brake can rely on its stable structure to complete various tasks excellently, providing solid guarantees for the company's efficient production. Versatile Applications Across Industries With its excellent performance, the MB8-110T/3200 CNC Press Brake has found a broad application space in multiple industries. In the elevator manufacturing industry, the side panels, door panels and various internal structural parts of the elevator car all need to be precisely bent. MB8-110T/3200 CNC Press Brake can accurately bend metal sheets of different materials according to the special size and precision requirements of elevator components to ensure the quality and safety of elevator components. Its stable processing performance not only improves the production efficiency of elevator manufacturing, but also provides strong support for the quality improvement of elevator products. In the field of chassis and cabinet production, the chassis and cabinets of various electronic equipment have strict requirements for dimensional accuracy and appearance flatness. MB8-110T/3200 CNC Press Brake can meet the complex requirements of plate bending in the production process of chassis and cabinets with high-precision bending effects. From simple right-angle bending to bending with special angles and shapes, it can easily cope with it, helping enterprises to produce chassis and cabinet products with exquisite appearance and stable structure, and enhance the competitiveness of enterprises in the market of electronic equipment supporting products. In addition, in industries such as metal furniture manufacturing and electrical equipment housing production, MB8-110T/3200 CNC Press Brake also plays an important role. The frame structure of metal furniture and the protective shell of electrical equipment are inseparable from precise bending processing. This CNC Press Brake provides reliable technical support for the product manufacturing of these industries with its efficient and precise processing capabilities, helping enterprises to produce more high-quality products to meet market demand. Cutting-Edge CNC and Drive Systems With the continuous advancement of science and technology, MB8-110T/3200 CNC Press Brake is also constantly integrating cutting-edge technology to improve its performance and intelligence level. Many CNC Press Brakes of this model are equipped with advanced CNC systems, such as DELEM DA53Tx, DA58Tx, DA66S, DA69S, etc. These CNC systems use computer programming technology to achieve precise control of the bending process. The operator only needs to enter the required bending angle, length, number of times and other parameters in the control system, and the equipment can automatically perform precise operations according to the set program. This automated and intelligent control method not only greatly improves the processing accuracy, but also reduces the errors caused by manual operation, and effectively improves the stability of product quality. At the same time, the CNC system also has a memory storage function, which can save a variety of processing parameters, making it convenient for operators to quickly call them in subsequent production, further improving production efficiency. In terms of the drive system, some MB8-110T/3200 CNC Press Brakes use advanced electro-hydraulic synchronization technology or servo drive technology. Electro-hydraulic synchronization technology uses high-precision sensors and hydraulic control systems to achieve synchronous operation when dual cylinders are driven, ensuring the stability and consistency of the slider during up and down movement, thereby improving bending accuracy. Servo drive technology uses the high responsiveness and precise control capabilities of servo motors to achieve precise adjustment of bending speed and position. Compared with traditional hydraulic drive methods, servo drive technology performs better in energy saving, can effectively reduce the energy consumption of equipment, and improve the operating efficiency and processing accuracy of equipment. These advanced drive technologies provide strong power support for the efficient and precise operation of MB8-110T/3200 CNC Press Brake, making it stand out in the market competition. Future-Proofing Your Metalworking Workflow Today, as competition in the metal processing industry becomes increasingly fierce, the MB8-110T/3200 CNC Press Brake has become a powerful assistant for many companies to improve production efficiency and ensure product quality with its powerful performance, wide application fields and advanced technology. With the continuous innovation and development of technology, it is believed that this CNC Press Brake will continue to shine in the future market, inject new vitality into the development of the metal processing industry, and promote the industry to a higher level. To learn more about how KRRASS CNC Press Brakes can enhance your productivity, visit or contact our technical team for a free consultation. TIME BUSINESS NEWS
Hypebeast
17-07-2025
- Automotive
- Hypebeast
Mercedes-Benz Unveils All-Electric CLA Shooting Brake
Summary Mercedes-Benzhas revealed the all-newCLAShooting Brake, the first estate model in the brand's lineup to feature a fullyelectricpowertrain. Launching in Europe in March 2026, the CLA Shooting Brake blends performance, practicality and advanced EQ technology with an extended WLTP-estimated range of up to 470 miles. With up to 192 miles of range gained in just 10 minutes of charging, the car promises everyday usability with high-speed efficiency. Sporting a sleek, star-lit panoramic roof and an illuminated front panel adorned with 142 LED stars, the CLA Shooting Brake debuts with a refined, futuristic design. The 85 kWh battery powers a new two-speed gearbox and an electric drivetrain offering up to 260 kW. Rear-wheel and all-wheel-drive versions deliver acceleration as quick as 0–62 mph in 6.8 seconds. The interior brings cutting-edge luxury with a floating MBUX Superscreen powered by the Unity Game Engine and ChatGPT-enhanced voice assistant. Beyond its style and digital depth, the Shooting Brake is built for daily life, offering 455–1,290 liters of cargo space, a 101-liter frunk, roof rails and nearly 4,000 lbs of towing capacity. Hybrid variants with 48-volt systems and multiple trim options are expected to join the range early next year.
Business Wire
08-07-2025
- Business
- Business Wire
Abdera Therapeutics Appoints Rachael Brake, Ph.D., as Chief Scientific Officer
SOUTH SAN FRANCISCO, Calif.--(BUSINESS WIRE)--Abdera Therapeutics Inc., a clinical-stage biopharmaceutical company leveraging its advanced antibody engineering ROVEr™ platform to design and develop tunable precision radiopharmaceuticals for cancer, today announced the appointment of Rachael Brake, Ph.D., as chief scientific officer. Dr. Brake brings more than 20 years of experience in the biopharmaceutical industry building and leading cross functional teams across basic and applied research, clinical and business development. 'We are thrilled to welcome Dr. Rachael Brake as our new chief scientific officer,' said Lori Lyons-Williams, president and chief executive officer. 'Rachael brings a distinguished career in oncology research and clinical development, with a proven ability to drive innovative scientific discoveries into impactful therapies for patients. Her deep expertise and leadership will be instrumental in maximizing the potential of our proprietary precision radiopharmaceutical platform.' 'Abdera's ROVEr™ platform stands at the forefront of radiopharmaceutical innovation in cancer treatment, empowering us to engineer targeted medicines with tunable PK properties, optimizing tumor uptake, circulation half-life and clearance rates. Collectively, the features of ROVEr™ will maximize the therapeutic index for this class of drugs and has the potential to transform how we consider delivering precision medicine,' said Dr. Brake. 'This is a truly transformative time for Abdera with clinical validation of ABD-147 emerging and ABD-320 expected to begin human clinical trials soon. I am energized to join this exceptional team and eager to shape the future of precision medicine with this new class of cancer therapy.' Dr. Brake joins Abdera from Zephyr AI where she served as chief scientific officer. Previously, Dr. Brake was the chief scientific officer at Corbus Pharmaceuticals where she built and led a research and development team and advanced multiple oncology programs into clinical development. Prior to her work at Corbus, Dr. Brake spent 11 years at Takeda Oncology, most recently as head of U.S. medical affairs, oncology business unit and as vice president, global program leader, oncology therapeutic area. In these roles, Dr. Brake managed a portfolio of programs and cross-functional teams responsible for the preclinical and clinical exploration of various solid tumor drug candidates spanning diverse mechanisms of action. Prior to joining Takeda, Dr. Brake was a research scientist at Amgen where she held increasing levels of responsibility culminating in the site lead in Cambridge, MA for the therapeutic innovation unit. Dr. Brake began her career as a research scientist at the Western Australian Institute for Medical Research and Woden Valley Hospital. She holds a Ph.D. in molecular biology and biochemistry from the University of Western Australia. About ABD-147 ABD-147 is a targeted radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225 Ac), a highly potent alpha-emitting radioisotope, to solid tumors expressing delta-like ligand 3 (DLL3) with high affinity. DLL3 is a protein in the Notch pathway that is critical for the development and regulation of neuroendocrine versus epithelial cell differentiation in the lungs. In certain high grade neuroendocrine carcinomas including small cell lung cancer (SCLC), DLL3 is upregulated and specifically expressed on the cell surface in more than 80% of cases. In contrast, DLL3 is absent or very rarely expressed on the surface of nonmalignant cells. Given the high specificity of DLL3 expression on cancer cells and the distinct mechanism of action, DLL3 represents a compelling target for treating SCLC and other DLL3+ solid tumors with targeted radiotherapy. The U.S. Food and Drug Administration (FDA) has granted Fast Track designation to ABD-147 for the treatment of patients with extensive stage small cell lung cancer (ES-SCLC) who have progressed on or after platinum-based chemotherapy and Orphan Drug Designation to ABD-147 for the treatment of neuroendocrine carcinoma. ABD-147 is currently being evaluated in a first-in-human Phase 1 clinical trial in patients with SCLC or large cell neuroendocrine carcinoma of the lung who have previously received platinum-based therapy. About ABD-320 ABD-320 is a targeted radiopharmaceutical biologic therapy engineered to deliver Actinium-225 (225 Ac) to solid tumors expressing 5T4. This oncofetal protein is rarely expressed in normal adult tissues but has been shown to be up-regulated in multiple cancer types, including colorectal, head and neck, non-small cell lung, pancreatic, gastric, mesothelioma, bladder, renal, cervical, ovarian, and breast cancers. By driving tumor cell migration and survival, 5T4 plays a key role in cancer progression and is associated with advanced disease, increased invasiveness, and poor clinical outcomes in solid tumors. ABD-320 was developed leveraging Abdera's ROVEr™ platform and is custom-engineered to achieve an ideal balance of tumor uptake and retention while avoiding systemic radiotoxicities. Preclinical data with ABD-320 demonstrates potent anticancer activity. ABD-320 represents the first radiopharmaceutical therapy in development to address 5T4. About Abdera Abdera Therapeutics is a clinical-stage biopharmaceutical company leveraging antibody engineering to design and develop new precision radiopharmaceuticals for cancer. Abdera's R adio O ptimized V ector E nginee r ing (ROVEr™) proprietary platform enables the company to engineer potential best-in-class therapies for both clinically validated and novel targets that deliver potent radioisotopes capable of emitting alpha or beta particles to selectively destroy cancer cells. Abdera's lead program, ABD-147, is a next-generation precision radiopharmaceutical biologic therapy designed to deliver Actinium-225 (225 Ac) to solid tumors expressing delta-like ligand 3 (DLL3) for the treatment of small cell lung cancer (SCLC) and large cell neuroendocrine carcinoma (LCNEC). Headquartered in South San Francisco, CA, Abdera also has offices in Vancouver, British Columbia, Canada. To learn more, please visit and follow us on LinkedIn and X.
Scoop
01-07-2025
- Automotive
- Scoop
Children Most At Risk As Government Forces Reversals Of Safe Speeds On 1 July
Press Release – Brake NZ Just as the school holidays get under way, children around the country will be at higher risk on streets in their neighbourhoods as the Setting of Speed Limits Rule (the Rule) introduced by Minister Simeon Brown and implemented by current Minister ofTransport Chris Bishop requires councils to revert to dangerous higher speed limits from 1 July, with variable speeds in place only at school gates at the start and end of the school day. 'Children across the country are at risk from higher speeds when they're walking, biking or scooting around their neighbourhoods. If hit by a vehicle going 50km/h, children have an 80% higher likelihood of being killed or seriously injured than at 30km/h. We also know that 85% of crashes that injure or kill people on streets around schools happen outside of those short periods at the beginning and end of the school day', says Caroline Perry, NZ Director of Brake, the road safety charity, and a spokesperson for the Save our Safe Streets campaign. 'The heightened risk is especially concerning in Auckland, where Auckland Transport has taken an unusually strict interpretation of the Rule that has seen over 1400 mainly quiet residential streets swept up in speed limit reversals. Not only has AT gone far further than other councils in applying the rule, they have rushed the work, resulting in confusing, incomplete, contradictory and dangerous signage,' says Ms Perry. The Save our Safe Streets campaign is an alliance of leading road safety experts and transport advocates. In a briefing paper to Auckland Council's Transport, Resilience and Infrastructure Committee, they have documented AT's flawed approach to the Rule. In particular they note that the rollout of reversals back to unsafe speeds – against the wishes of impacted communities – will result in harm to Aucklanders, wasteful expenditure, unnecessary disruption, higher costs and more extensive traffic management processes, environmental and economic damage, and a less efficient, more congested transport network. Group member Pippa Coom says, 'Instead of doing everything it could to defend its world-class road safety programme from ill-advised reversals, AT has capitulated effectively throwing Aucklanders under the bus at every opportunity. Moreover, the small handful of streets that have retained safe speeds were saved only due to tenacious intervention by residents and advocates – with neither public acknowledgement nor thanks from AT.' 'Throughout, AT has operated in secret. It has not been transparent or proactive in its dealings with Council and the public about its process around the Speed Limit Rule, nor has it communicated the impacts on communities. AT has had plenty of opportunities to limit the perverse and harmful outcomes of the Speed Limit Rule but chose not to, despite increasingly urgent requests from community leaders, advocates, and elected members,' says Ms Coom. Councillor Julie Fairey expressed profound disappointment in the outcome for Auckland. 'AT just were not interested in moving on this, despite being given plenty of opportunities and excuses they could use. Sadly, I think we won't have a full realisation of the liability question until someone is hurt or killed. The advocacy efforts on this have been amazing, huge amounts of research and effort put in, all voluntary, and the stonewalling at senior levels of AT has been heartbreaking'. She has gone on to say, 'I find it particularly cruel that many of the staff who have had to roll this out were those who understand the evidence, championed and implemented safer speeds.' The higher speeds kick in on 1 July, during the school holidays, and the reality of central government overriding evidence and local preference is only just becoming clear to many communities. For example, a stretch of beach north of Auckland is rising from 50km/h to 70km/h against community wishes, while further south, a nonsensical 100km/h will be installed on a dangerous stretch of road through a Lake Taupō campground. Ms Perry adds, 'A few fortunate communities, such as Rakaia and Nelson, will be rightly celebrating their common-sense retention of safe speeds, but this only came after a hard-fought campaign resulted in public consultation on the proposed speed limit increases to these stretches of road.' 'It should be common-sense to always apply the evidence to keep children safe. Everyone benefits when children can move independently, when people are free to walk and cycle without fear of serious injury and death, and when streets are safer for all of us,' says Ms Perry.
Scoop
01-07-2025
- Politics
- Scoop
Children Most At Risk As Government Forces Reversals Of Safe Speeds On 1 July
Just as the school holidays get under way, children around the country will be at higher risk on streets in their neighbourhoods as the Setting of Speed Limits Rule (the Rule) introduced by Minister Simeon Brown and implemented by current Minister of Transport Chris Bishop requires councils to revert to dangerous higher speed limits from 1 July, with variable speeds in place only at school gates at the start and end of the school day. 'Children across the country are at risk from higher speeds when they're walking, biking or scooting around their neighbourhoods. If hit by a vehicle going 50km/h, children have an 80% higher likelihood of being killed or seriously injured than at 30km/h. We also know that 85% of crashes that injure or kill people on streets around schools happen outside of those short periods at the beginning and end of the school day', says Caroline Perry, NZ Director of Brake, the road safety charity, and a spokesperson for the Save our Safe Streets campaign. 'The heightened risk is especially concerning in Auckland, where Auckland Transport has taken an unusually strict interpretation of the Rule that has seen over 1400 mainly quiet residential streets swept up in speed limit reversals. Not only has AT gone far further than other councils in applying the rule, they have rushed the work, resulting in confusing, incomplete, contradictory and dangerous signage,' says Ms Perry. The Save our Safe Streets campaign is an alliance of leading road safety experts and transport advocates. In a briefing paper to Auckland Council's Transport, Resilience and Infrastructure Committee, they have documented AT's flawed approach to the Rule. In particular they note that the rollout of reversals back to unsafe speeds – against the wishes of impacted communities – will result in harm to Aucklanders, wasteful expenditure, unnecessary disruption, higher costs and more extensive traffic management processes, environmental and economic damage, and a less efficient, more congested transport network. Group member Pippa Coom says, 'Instead of doing everything it could to defend its world-class road safety programme from ill-advised reversals, AT has capitulated effectively throwing Aucklanders under the bus at every opportunity. Moreover, the small handful of streets that have retained safe speeds were saved only due to tenacious intervention by residents and advocates – with neither public acknowledgement nor thanks from AT.' 'Throughout, AT has operated in secret. It has not been transparent or proactive in its dealings with Council and the public about its process around the Speed Limit Rule, nor has it communicated the impacts on communities. AT has had plenty of opportunities to limit the perverse and harmful outcomes of the Speed Limit Rule but chose not to, despite increasingly urgent requests from community leaders, advocates, and elected members,' says Ms Coom. Councillor Julie Fairey expressed profound disappointment in the outcome for Auckland. 'AT just were not interested in moving on this, despite being given plenty of opportunities and excuses they could use. Sadly, I think we won't have a full realisation of the liability question until someone is hurt or killed. The advocacy efforts on this have been amazing, huge amounts of research and effort put in, all voluntary, and the stonewalling at senior levels of AT has been heartbreaking'. She has gone on to say, 'I find it particularly cruel that many of the staff who have had to roll this out were those who understand the evidence, championed and implemented safer speeds.' The higher speeds kick in on 1 July, during the school holidays, and the reality of central government overriding evidence and local preference is only just becoming clear to many communities. For example, a stretch of beach north of Auckland is rising from 50km/h to 70km/h against community wishes, while further south, a nonsensical 100km/h will be installed on a dangerous stretch of road through a Lake Taupō campground. Ms Perry adds, 'A few fortunate communities, such as Rakaia and Nelson, will be rightly celebrating their common-sense retention of safe speeds, but this only came after a hard-fought campaign resulted in public consultation on the proposed speed limit increases to these stretches of road.' 'It should be common-sense to always apply the evidence to keep children safe. Everyone benefits when children can move independently, when people are free to walk and cycle without fear of serious injury and death, and when streets are safer for all of us,' says Ms Perry.
