Latest news with #CD20
Yahoo
09-08-2025
- Business
- Yahoo
Market Rallies as Trump Opens 401(k) Floodgates: Crypto Daybook Americas
By Francisco Rodrigues (All times ET unless indicated otherwise) Crypto markets rallied in the past 24 hours, with the CoinDesk 20 (CD20) index rising 5.3% as fresh U.S. policy signals and regulatory clarity supported risk appetite across the sector. Bitcoin (BTC) gained a relatively muted 1.3% to $116,500. The rally took off after President Donald Trump signed an executive order opening 401(k) retirement plans to a broader range of investments, including cryptocurrencies. The order directs the Department of Labor and Securities and Exchange Commission to publish new guidance for retirement accounts. 'This move effectively opens access to bitcoin and other cryptocurrencies for retirement investors, unlocking a staggering $8.7 trillion in assets under management.,' James Butterfill, head of research at CoinShares, said in an emailed statement. Jake Ostrovskis, OTC trader at Wintermute, told CoinDesk that the impact of the move could not be understated. 'Just a 2% allocation to Bitcoin and Ethereum would represent 1.5x the total cumulative ETF inflows to date, while a 3% allocation would more than double the entire market,' Ostrovskis said. 'Critically, these would be largely price-insensitive buyers focused on meeting allocation benchmarks rather than tactical trading.' In practice, that means 401(k) funds would create 'sustained, predictable demand flows that could provide a structural bid for digital assets regardless of short-term price volatility,' Ostrovskis added. While crypto has never been formally banned from the retirement investments, previous guidance strongly discouraged fiduciaries from offering it. Meanwhile, the Ethereum blockchain hit a new record for average daily transactions this week, according to data from Dune Analytics. The increase was underpinned by the SEC's clarification earlier this week that certain liquid staking models don't constitute securities under the 1933 Securities Act, making it safer for institutions to offer staking services. Ether's (ETH) price surged 4.6% over the past 24 hours to near $3,900. While fireworks were going off in the crypto sector, TradFi was more subdued. The S&P 500 dropped in Thursday's session, and the Nasdaq closed 0.35% higher, furthering the concentration of megacaps in the indexes. The 10 largest stocks now account for 76% of the entire stock market capitalization, data shared by Barchart shows. Gold rose on tariffs being imposed on some bullion bars. Looking ahead, investors are bracing for July's inflation report, due next week, which may influence the odds of a dovish Fed interest-rate cut in September. Stay alert! What to Watch Crypto Aug. 15: Record date for the next FTX distribution to holders of allowed Class 5 Customer Entitlement, Class 6 General Unsecured and Convenience Claims who meet pre-distribution requirements. Aug. 18: Coinbase Derivatives will launch nano SOL and nano XRP U.S. perpetual-style futures. Macro Aug. 8: Federal Reserve Governor Adriana D. Kugler's resignation becomes effective, creating an early vacancy on the Board of Governors that allows President Trump to nominate a successor. Aug 8: President Trump's deadline for Russia to commit to a ceasefire and peace deal in Ukraine, with intensified U.S. sanctions and secondary tariffs on countries purchasing Russian energy if the deadline is not met. Aug. 8: U.S. President Donald Trump hosts Armenian Prime Minister Nikol Pashinyan and Azerbaijani President Ilham Aliyev at the White House to sign a peace agreement. The U.S. will also sign bilateral economic agreements to promote trade and regional stability. Aug. 8, 7 p.m.: Colombia's National Administrative Department of Statistics releases July consumer price inflation data.. Inflation Rate MoM Est. 0.19% vs. Prev. 0.1% Inflation Rate YoY Est. 4.81% vs. Prev. 4.82% Aug. 12, 8 a.m.: The Brazilian Institute of Geography and Statistics (IBGE) releases July consumer price inflation data. Inflation Rate MoM Prev. 0.24% Inflation Rate YoY Prev. 5.35% Aug. 12, 8:30 a.m.: The U.S. Bureau of Labor Statistics (BLS) releases July consumer price inflation data. Core Inflation Rate MoM Est. 0.3% vs. Prev. 0.2% Core Inflation Rate YoY Est. 3% vs. Prev. 2.9% Inflation Rate MoM Est. 0.2% vs. Prev. 0.3% Inflation Rate YoY Est. 2.8% vs. Prev. 2.7% Earnings (Estimates based on FactSet data) Aug. 8: TeraWulf (WULF), pre-market, -$0.06 Aug. 11: Exodus Movement (EXOD), post-market, $0.12 Aug. 12: Bitfarms (BITF), pre-market, -$0.02 Aug. 12: Fold Holdings (FLD), post-market, N/A Aug. 15: BitFuFu (FUFU), pre-market, $0.07 Token Events Governance votes & calls BendDAO is voting on a plan to stabilize BEND by burning 50% of treasury tokens, restarting lender rewards, and launching monthly buybacks using 20% of protocol revenue. Voting ends Aug. 10. 1inch DAO is voting on a $1.88 million grant to fund its participation in nine global crypto events through late 2025. The proposal aims to boost developer engagement, grow institutional ties and expand adoption across ecosystems like Ethereum and Solana. Voting ends Aug. 10. Aug. 8, 11:30 a.m.: Axie Infinity to host a town hall on Discord. Unlocks Aug. 9: Immutable (IMX) to unlock 1.3% of its circulating supply worth $12.66 million. Aug. 12: Aptos (APT) to unlock 1.73% of its circulating supply worth $52.59 million. Aug. 15: Avalanche (AVAX) to unlock 0.39% of its circulating supply worth $39.25 million. Aug. 15: Starknet (STRK) to unlock 3.53% of its circulating supply worth $16.19 million. Aug. 15: Sei (SEI) to unlock 0.96% of its circulating supply worth $17.21 million Aug. 16: Arbitrum (ARB) to unlock 1.8% of its circulating supply worth $39.21 million. Aug. 18: Fasttoken (FTN) to unlock 4.64% of its circulating supply worth $91.6 million. Token Launches Aug. 8: Pudgy Penguins (PENGU) to be listed on Arkham Exchange. Conferences The CoinDesk Policy & Regulation conference (formerly known as State of Crypto) is a one-day boutique event held in Washington on Sept. 10 that allows general counsels, compliance officers and regulatory executives to meet with public officials responsible for crypto legislation and regulatory oversight. Space is limited. Use code CDB10 for 10% off your registration through Aug. 31. Day 3 of 5: Rare EVO (Las Vegas) Day 2 of 2: bitcoin++ (Riga, Latvia) Aug. 9-10: Baltic Honeybadger 2025 (Riga, Latvia) Aug. 9-10: Conviction 2025 (Ho Chi Minh City, Vietnam) Aug. 11: Paraguay Blockchain Summit 2025 (Asuncion) Aug. 11-13: AIBB 2025 (Istanbul) Aug. 11-17: Ethereum NYC (New York) Aug. 13-14: CryptoWinter '25 (Queenstown, New Zealand) Token Talk By Shaurya Malwa Ethereum's seven-day average daily transactions hit a record 1.74 million as staked ETH levels climbed to an all-time high. Over 36 million ETH, nearly 30% of total supply, is now locked in staking contracts, according to Dune Analytics. The increase followed the SEC's clarification that certain liquid staking activities and staking receipt tokens aren't securities under the 1933 Act if they meet strict assumptions. The ruling reduced legal overhang, opening the door for greater institutional participation. The trend is also backed by yield-seeking holders and growing treasury allocations from publicly listed firms, tightening liquid supply. Public companies now control $11.77 billion in ETH, led by BitMine Immersion Technologies ($3.2 billion), SharpLink Gaming ($2 billion), and The Ether Machine ($1.3 billion). Vitalik Buterin said treasuries are 'good and valuable' for Ethereum but warned that excessive leverage could spark cascading liquidations. ETH has rallied 163% from April lows with more than 500,000 ETH ($1.8 billion) staked in the first half of June alone — a pace CryptoQuant's Onchainschool said reflects 'rising confidence and a continued drop in liquid supply.' Derivatives Positioning Total BTC futures open interest sits at $80.65 billion, flat on the day after a mild pullback earlier this week. CME remains dominant with a 20% share, underscoring steady institutional exposure. Binance and OKX flows were mixed, with OKX OI up 3.95% in the past 24 hours despite heavier intraday swings. ETH liquidations led the market over the past 24 hours at $188.7 million, dwarfing BTC's $52.6 million and XRP's $29 million. The largest liquidation was a $34.28 million ETH-USDT long position on HTX, reflecting concentrated leverage in ETH perps ahead of price swings. Liquidation data skews heavily to the short side, with $319 million in shorts wiped versus $91 million in longs, suggesting that the recent upside caught positioning off guard and may have forced momentum-driven covering across majors. BTC open interest distribution shows CME's basis holding firm at 2.61%, suggesting sustained carry demand from TradFi desks, while Binance's basis is muted at 0.61%, indicating less aggressive directional leverage from offshore traders. ETH funding rates remain elevated at or near exchange-imposed caps, signaling persistent long bias despite the heavy wipeout of shorts. This combination — high funding plus fresh OI — suggests traders are rotating back into directional plays rather than fully deleveraging. Market Movements BTC is down 0.43% from 4 p.m. ET Thursday at $116,701.75 (24hrs: +0.22%) ETH is up 0.68% at $3,900.02 (24hrs: +2.08%) CoinDesk 20 is up 2.2% at 4,046.33 (24hrs: +3.94%) Ether CESR Composite Staking Rate is unchanged at 2.9% BTC funding rate is at 0.004% (4.4052% annualized) on Binance DXY is down 0.16% at 98.24 Gold futures are up 1.12% at $3,492.50 Silver futures are up 0.80% at $38.60 Nikkei 225 closed up 1.85% at 41,820.48 Hang Seng closed down 0.89% at 24,858.82 FTSE is unchanged at 9,095.08 Euro Stoxx 50 is up 0.13% at 5,339.07 DJIA closed on Thursday down 0.51% at 43,968.64 S&P 500 closed unchanged at 6,340.00 Nasdaq Composite closed up 0.35% at 21,242.70 S&P/TSX Composite closed down 0.57% at 27,761.27 S&P 40 Latin America closed up 2.03% at 2,666.61 U.S. 10-Year Treasury rate is up 0.6 bps at 4.25% E-mini S&P 500 futures are up 0.26% at 6,383.25 E-mini Nasdaq-100 futures are up 0.28% at 23,562.75 E-mini Dow Jones Industrial Average Index are up 0.17% at 44,155.00 Bitcoin Stats BTC Dominance: 60.82% (-0.31%) Ether to bitcoin ratio: 0.03343 (0.42%) Hashrate (seven-day moving average): 966 EH/s Hashprice (spot): $57.95 Total Fees: 5.2 BTC / $602,389 CME Futures Open Interest: 137,710 BTC BTC priced in gold: 34.4 oz BTC vs gold market cap: 9.73% Technical Analysis The ETH/SOL ratio is testing a key weekly resistance (~22.4); a confirmed breakout could trigger strong continuation with ether rising toward the 34-36 SOL range. RSI shows strong momentum (70+) with no bearish divergence, supporting the breakout potential. Unless rejected, the setup favors ETH outperformance vs. SOL on confirmation. Crypto Equities Strategy (MSTR): closed on Thursday at $402.01 (+4.85%), -0.25% at $401 in pre-market Coinbase Global (COIN): closed at $310.79 (+2.38%), +0.86% at $313.45 Circle (CRCL): closed at $152.93 (-5.43%), +1.12% at $154.64 Galaxy Digital (GLXY): closed at $28.09 (+2.74%), +1.35% at $28.47 MARA Holdings (MARA): closed at $15.95 (+0.38%), -0.13% at $15.93 Riot Platforms (RIOT): closed at $11.58 (-0.69%), +0.35% at $11.62 Core Scientific (CORZ): closed at $14.35 (+1.7%), +0.84% at $14.47 CleanSpark (CLSK): closed at $10.72 (-2.55%), unchanged in pre-market CoinShares Valkyrie Bitcoin Miners ETF (WGMI): closed at $25.37 (-1.4%) Semler Scientific (SMLR): closed at $37.54 (+5.27%), unchanged in pre-market Exodus Movement (EXOD): closed at $31.34 (+6.74%) SharpLink Gaming (SBET): closed at $23.36 (+5.51%), +2.57% at $23.96 ETF Flows Spot BTC ETFs Daily net flows: $277.4 million Cumulative net flows: $54 billion Total BTC holdings ~1.29 million Spot ETH ETFs Daily net flows: $222.3 million Cumulative net flows: $9.37 billion Total ETH holdings ~5.6 million Source: Farside Investors Overnight Flows Chart of the Day The memecoin sector's outperformance of the wider cryptocurrency market was short-lived, showing that while its heightened volatility could present opportunities, market timing is critical. Meanwhile, layer-2 tokens have outperformed in the past month, as Velo data shows. The worst-performing sector throughout the period were gaming-related tokens, which consistently underperformed. While You Were Sleeping Ethereum Transactions Hit Record High as Staking, SEC Clarity Fuel ETH Rally (CoinDesk): The SEC's softer stance on liquid staking is spurring institutional ETH accumulation, with nearly 30% of supply now locked in staking contracts and corporate treasuries holding more than $11 billion worth of ether. Crypto's $25 Billion Spree Sparks Unease Even Among Insiders (Bloomberg): Several fund managers warned that if altcoin-focused treasury firms' valuations fall below their crypto holdings' value, forced selling could follow, deepening losses and potentially ending the current crypto bull cycle. XRP Surges 12% as Traders Bet on Big Price Swings with 'Straddle' Strategy (CoinDesk): Traders are placing large Deribit long straddles — buying calls and puts with identical strikes and expiries, risking only the premiums paid for potentially unlimited upside or sizable gains if prices plunge. Binance Teams Up With BBVA to Let Customers Keep Assets Off Exchange (Financial Times): After a massive U.S. fine, Binance is giving traders the option of storing collateral in U.S. Treasuries at BBVA, highlighting traditional banks' deeper push into crypto markets. Israeli Security Cabinet Approves Gaza Control Plan (The Wall Street Journal): Prime Minister Benjamin Netanyahu's proposal — seizing all of Gaza, then handing it to Arab coalition forces for day-to-day governance while keeping an Israeli-controlled perimeter — is drawing broad domestic and global pushback. Trump Tariffs on Russia's Oil Buyers Bring Economic, Political Risks (Reuters): The U.S. president's secondary tariffs, starting with India, could risk raising fuel prices, straining relations with China and India and hurting Republicans' midterm election prospects with potentially no gain. In the Ether
Yahoo
04-07-2025
- Business
- Yahoo
ATOM Consolidates as Bitcoin Takes Driving Seat, Finds Support at $4.20
The altcoin market took a backseat on Thursday as crypto majors bitcoin and ether attempted to rally to new highs. As billions of dollars worth of liquidity flowed into shorting bitcoin on the brink of record highs, altcoins like ATOM consolidated, finding support at the $4.20 level. Typically when bitcoin rallies altcoin price action is muted and the inverse is true when bitcoin consolidates, so ATOM could be primed for a rally once bitcoin begins to cool off. Technical analysis ATOM-USD traded within a range of $4.09 to $4.26 during the 24-hour period from 2 July 16:00 to 3 July 15:00, representing a 4% swing. Key support established at $4.16-$4.17 with high volume buying emerging at the $4.20 level during the 13:00 hour session on July 3rd. Despite reaching a peak of $4.26 during the 07:00 hour, ATOM failed to sustain momentum above the $4.25 resistance level. In the last 60 minutes from 3 July 14:24 to 15:23, ATOM-USD declined from $4.24 to $4.21, representing a 0.73% decrease. Sharp selloff occurred between 15:03-15:07, dropping to a session low of $4.19, before staging a recovery. Final 15 minutes showed stabilization with price consolidation around $4.21, suggesting potential short-term equilibrium. CD20 Index Surges 2% Before Profit-Taking Emerges The CD20 demonstrated significant volatility in the last 24 hours from 2 July 16:00 to 3 July 15:00, reaching a peak of $1,811.11 before retracing to $1,793.55, with an overall range of $37.27 (2%). After establishing support around $1,780 during early hours, the index staged an impressive rally through the morning session of 3 July, gaining momentum particularly between 09:00-14:00 before profit-taking emerged in the final hour.
Yahoo
27-06-2025
- Business
- Yahoo
NEAR Tumbles 5% as Altcoin Market Fails to Sustain Rally
The cryptocurrency market is feeling the effects of broader uncertainty in equities as NEAR Protocol dropped 5.01% from $2.16 to $2.06 during the 24-hour period from June 25 to June 26. The bearish pressure culminated in a sharp sell-off between 13:36-13:51 on June 26, when NEAR plunged to a session low of $2.05 on heavy volume exceeding 154K tokens. Technical Analysis NEAR formed a clear bearish channel with resistance at $2.17-$2.19 and support at $2.09-$2.10, which was eventually broken on heavy volume exceeding 3.9M NEAR during the 12:00 hour. Notable volume spikes occurred during the 09:00-12:00 timeframe as selling pressure intensified, with the asset reaching its lowest point at $2.05 during the 13:00 hour. A potential double bottom pattern formed in the final 15 minutes of the analyzed period as buyers stepped in with increasing volume, suggesting possible short-term stabilization. The total price range over the 24-hour period was $0.14 (6.55%), indicating significant volatility. CoinDesk 20 Index Whipsaws as Early Gains Evaporate The CD20 demonstrated significant volatility over the last 24 hours from 25 June 15:00 to 26 June 14:00, with a price range of $22.40 (1.29%). After reaching a peak of $1,762.50, the index retreated to $1,740.10, as early bullish momentum gave way to consistent selling pressure throughout the morning session. This pattern erased nearly all gains and suggests potential further downside if support at $1,740 fails to hold.
Yahoo
09-06-2025
- Business
- Yahoo
ATOM Struggles After Failed Breakout, Recovers With New Support at $4.237
ATOM ATOM, the token of the Cosmos ecosystem, experienced volatility over the past 24 hours, with the price ranging 2.76% and peaking at $4.327. Strong resistance emerged around that level, with high trading volume creating a rejection zone that prevented further advances, according to CoinDesk Research's technical analysis model. The Cosmos ecosystem, a network comprised of many independent blockchains, continues expanding its cross-chain capabilities through the Eureka upgrade, which kicked in April, enabling seamless communication with the Ethereum blockchain. Institutional developments including Bitbank's ATOM listing with promotional fee structures and Canary Capital's exploration of a Cosmos-backed ETF also provided support. Support established around $4.21, with price stabilizing near $4.233 during consolidation phase. Significant hourly recovery occurred between 07:33-08:02, with price surging to $4.239 on heavy volume exceeding 16,000 units. New support level formed at $4.237 following the 1.4% bounce from the hour's low. The CD20 demonstrated notable volatility over the 24-hour period, reaching a peak of 1751.049 before falling back, with an overall range of 22.573 points (1.3%). After establishing a 24-hour high during the 22:00 hour on June 8th, CD20 entered a consolidation phase, retracing approximately 50% of its gains while maintaining support above the 1730 level, suggesting potential stabilization following the recent upward momentum. Disclaimer: Parts of this article were generated with the assistance from AI tools and reviewed by our editorial team to ensure accuracy and adherence to our standards. For more information, see CoinDesk's full AI Policy. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Business Wire
15-05-2025
- Business
- Business Wire
Innate Pharma Highlights ANKET ® Abstracts Selected for the EHA 2025 Congress
MARSEILLE, France--(BUSINESS WIRE)--Regulatory News: Innate Pharma SA (Euronext Paris: IPH; Nasdaq: IPHA) (' Innate ' or the ' Company ') today announced that an abstract regarding IPH6501, its ANKET ® targeting CD20 B cells currently developed in relapsed and/or refractory Non-Hodgkin Lymphoma, has been selected for the European Hematology Association (EHA) Congress 2025, taking place June 12-15 in Milan, Italy. Abstract details Antitumor characterization of IPH6501, a novel il2v-armed tetraspecific NK cell engager targeting CD20 B cells, in DLBCL and FL patient samples, and in preclinical combination with R-CHOP Abstract Code: PS2004 Session: Poster session 2 Session Date/Time: Saturday, June 14, 2025, 18:30 – 19:30 CEST More information can be found on the EHA website. In addition, an abstract related to SAR'514/IPH6401 (developed by Sanofi) was accepted for online publication. Abstract Code: PB2850 About ANKET ® ANKET ® (A ntibody-based NK cell E ngager T herapeutics) is Innate's proprietary platform for developing next-generation, multi-specific natural killer (NK) cell engagers to treat certain types of cancer. This versatile, fit-for-purpose technology is creating an entirely new class of molecules to induce synthetic immunity against cancer. About IPH6501 IPH6501 is the first Antibody-based NK cell Engager Therapeutic to co-engage activating receptors on NK cells (NKp46 and CD16), IL-2R (but not the alpha subunit) through a variant of human IL-2, and a tumor antigen (CD20) via a single molecule, hence providing proliferation and activation signals targeted to NK cells and promoting their cytotoxic activity against CD20 expressing malignant cells. IPH6501 has shown better anti-tumor efficacy than approved benchmark antibodies in preclinical tumor models (Demaria, EHA 2023, Carrette, SITC 2024, Demaria et al, Science Immunology 2024). IPH6501 is currently being evaluated in a Phase 1/2 multicenter trial (NCT06088654), investigating the safety and tolerability of IPH6501 in patients with relapsed and/or refractory CD20-expressing B-cell Non-Hodgkin's Lymphoma. About Innate Pharma Innate Pharma S.A. is a global, clinical-stage biotechnology company developing immunotherapies for cancer patients. Its innovative approach aims to harness the innate immune system through three therapeutic approaches: multi-specific NK Cell Engagers via its ANKET ® (Antibody-based NK cell Engager Therapeutics) proprietary platform and Antibody Drug Conjugates (ADC) and monoclonal antibodies (mAbs). Innate's portfolio includes several ANKET ® drug candidates to address multiple tumor types as well as IPH4502, a differentiated ADC in development in solid tumors. In addition, anti-KIR3DL2 mAb lacutamab is developed in advanced form of cutaneous T cell lymphomas and peripheral T cell lymphomas, and anti-NKG2A mAb monalizumab is developed with AstraZeneca in non-small cell lung cancer. Innate Pharma is a trusted partner to biopharmaceutical companies such as Sanofi and AstraZeneca, as well as leading research institutions, to accelerate innovation, research and development for the benefit of patients. Headquartered in Marseille, France with a US office in Rockville, MD, Innate Pharma is listed on Euronext Paris and Nasdaq in the US. Learn more about Innate Pharma at Follow us on LinkedIn and X. Information about Innate Pharma shares Disclaimer on forward-looking information and risk factors This press release contains certain forward-looking statements, including those within the meaning of applicable securities laws, including the Private Securities Litigation Reform Act of 1995. The use of certain words, including 'anticipate,' 'believe,' 'can,' 'could,' 'estimate,' 'expect,' 'may,' 'might,' 'potential,' 'intend,' 'should,' 'will,' or the negative of these and similar expressions, is intended to identify forward-looking statements. Although the Company believes its expectations are based on reasonable assumptions, these forward-looking statements are subject to numerous risks and uncertainties, which could cause actual results to differ materially from those anticipated. These risks and uncertainties include, among other things, the uncertainties inherent in research and development, including related to safety, progression of and results from its ongoing and planned clinical trials and preclinical studies, review and approvals by regulatory authorities of its product candidates, the Company's reliance on third parties to manufacture its product candidates, the Company's commercialization efforts and the Company's continued ability to raise capital to fund its development. For an additional discussion of risks and uncertainties, which could cause the Company's actual results, financial condition, performance or achievements to differ from those contained in the forward-looking statements, please refer to the Risk Factors ('Facteurs de Risque") section of the Universal Registration Document filed with the French Financial Markets Authority ('AMF'), which is available on the AMF website or on Innate Pharma's website, and public filings and reports filed with the U.S. Securities and Exchange Commission ('SEC'), including the Company's Annual Report on Form 20-F for the year ended December 31, 2024, and subsequent filings and reports filed with the AMF or SEC, or otherwise made public by the Company. References to the Company's website and the AMF website are included for information only and the content contained therein, or that can be accessed through them, are not incorporated by reference into, and do not constitute a part of, this press release. In light of the significant uncertainties in these forward-looking statements, you should not regard these statements as a representation or warranty by the Company or any other person that the Company will achieve its objectives and plans in any specified time frame or at all. The Company undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law. This press release and the information contained herein do not constitute an offer to sell or a solicitation of an offer to buy or subscribe to shares in Innate Pharma in any country.
