Latest news with #CharlesRiver
CBS News
4 days ago
- Health
- CBS News
There are over 30 harmful algae blooms in Massachusetts lakes and ponds right now: See the list
Health officials in Massachusetts are spreading the word about harmful blooms of cyanobacteria, also known as blue-green algae, in lakes and ponds around the state. In Plymouth, the public health director told WBZ-TV that there are six ponds with cyanobacteria blooms that can make people and dogs "very sick." Signs are posted on the beaches to tell people not to swim at the water, and to keep their dogs away from shore. In Brookline on Tuesday, the town warned that a harmful bloom has been confirmed at the Brookline Reservoir, which is a popular walking area. Fishing is banned at the reservoir and no pets are allowed until further notice, the town said. Anyone who makes contact with the algae should rinse off immediately. Part of the Charles River near the Harvard Bridge also has an algae bloom. In 2024, the area experienced its first major bloom in four years. An algae bloom happens when cyanobacteria multiplies quickly in a highly concentrated area. It can cause the water to become pea soup-colored and sometimes smell bad. Warm weather, sunlight and excess nutrients in the water from runoff can make it grow faster. The bloom can release toxins that may cause skin irritation or gastrointestinal problems if ingested. Inhaling the water spray may also result in asthma-like symptoms, the state says. Here is the list of harmful cyanobacterial blooms in Massachusetts as of Aug. 6, according to a state dashboard. Lake Holland, Belchertown Chestnut Hill Reservoir, Boston Charles River--Downstream of Massachusetts Ave (the Harvard Bridge), Boston/Cambridge Quaboag Pond, Brookfield/East Brookfield Brookline Reservoir, Brookline Freeman Lake, Chelmsford Heart Pond, Chelmsford Rubber Thread Pond, Easthampton Seymour Pond, Harwich/Brewster West Reservoir, Harwich Schoolhouse Pond, Hyannis Long Pond, Marstons Mills Santuit Pond, Mashpee Clarks Cove, Nantucket Capaum Pond, Nantucket Hummock Pond, Nantucket Lake Cochituate-South Pond, Natick Crystal Lake, Newton Carbuncle Pond, Oxford Clear Pond, Plymouth Big Sandy Pond, Plymouth Billington Sea, Plymouth Great Herring Pond, Plymouth Little Herring Pond, Plymouth Russell Mill Pond, Plymouth Bass Pond, Springfield Lake Quannapowitt, Wakefield Hardy Pond, Waltham Glen Charlie Pond, Wareham Pequot Pond/Hampton Ponds, Westfield Blackstone Canal, Uxbridge
Reuters
5 days ago
- Business
- Reuters
Charles River profit forecast clouded by order cancellations from biotechs
Aug 6 (Reuters) - Charles River Laboratories' (CRL.N), opens new tab annual profit forecast raise on Wednesday was clouded by investor concerns about the higher number of order cancellations from clients, sending the contract research firm's shares down 8% in afternoon trading. The company's quarterly book-to-bill ratio – the number of orders versus those fulfilled – came in at 0.82x. Evercore ISI analyst Elizabeth Anderson said the ratio was below Wall Street expectations of 0.94x, adding some questions remain about demand environment in the sector. Charles River CEO Jim Foster said on a conference call that while proposals were higher in the quarter, cancellations from biotechs were also higher. Contract research organizations – including Charles River, Fortrea (FTRE.O), opens new tab and ICON (ICLR.O), opens new tab – have posted better-than-expected quarterly profit, reflecting a rebound in spending from pharmaceutical and biotech clients after a cautious stretch driven by tighter sector financing. Charles River's Foster, however, said that funding for smaller biotechs is still more cash constrained, due to the funding slowdown, and mid-sized biotechs are performing better, as many can support their R&D programs without external funding. "We are continuing to see clear signs that the biopharmaceutical demand is stabilizing, and in this environment, we are making gradual progress to return to organic revenue growth," he added. The Wilmington, Massachusetts-based company raised its 2025 adjusted profit forecast to $9.90 to $10.30 per share, from its previous range of $9.30 to $9.80. Charles River's overall second-quarter revenue came in at $1.03 billion, surpassing analysts' estimate of $985.1 million, according to data compiled by LSEG. On an adjusted basis, quarterly profit was $3.12 per share, above estimates of $2.50.
Yahoo
31-07-2025
- Business
- Yahoo
Charles River and BioTech Social Inc. Pursue Crowdfunding Partnership
Aim to Enhance Charles River Incubator and Accelerator Programs by adding crowdfunding features, aiding early-stage developers WILMINGTON, Mass., July 31, 2025--(BUSINESS WIRE)--Charles River Laboratories International, Inc. (NYSE: CRL) and BioTech Social Inc. (BSI) today announced the exploration of a potential client-centric collaboration to enable Charles River Incubator (CIP) and Accelerator (CAP) Program participants to access the BioTech Funding Portal, an investment crowdfunding platform for life science companies. "We're thrilled to explore this collaboration that will open up an exciting new funding pathway to bridge innovation with the right audiences and investors. This dynamic approach would potentially streamline the delivery of medicine to patients," said Kerstin Dolph, Corporate Senior Vice President, Global Manufacturing, Charles River. "We're always working to equip our clients with the tools and opportunities they need to fast-track drug development and therapies." If formalized, the contemplated strategic partnership would allow early-stage cell and gene therapy (CGT) developers to raise up to $5 million per year via the platform, accelerating development and enabling therapies to reach patients more quickly, because every moment matters. The BioTech Funding Portal, a subsidiary of BioTech Social Inc., exclusively lists life sciences companies, like participants of the CIP and CAP programs, acting as a conduit for crowdfunding of emerging biotech companies. "The mission of the BioTech Funding Portal is to harness the power of non-accredited investors to support research that might otherwise go unfunded – despite it addressing clear, unmet medical needs," said Neva West, PhD, CEO of BioTech Funding Portal. "Through our potential partnership with the CIP and CAP programs, we aim to help selected applicants cross the notorious funding 'valley of death' that so often threatens innovative, early-stage companies." Committed to Catalyzing CGTs from Discovery to CommercializationThe CIP and CAP programs were established in 2024, enabling developers to form a strong foundation for commercial viability. Benefits of both programs include consultative regulatory and quality expertise, and access to laboratory space and equipment. Building on the success of the inaugural CIP cohort, announced in April 2025, developers are now invited to apply for the next cohort. Subject to further agreement, applications may be jointly evaluated by Charles River and BioTech Social and possibly shortlisted in conjunction with the upcoming European Cell and Gene Therapy Summit in September. Chih-Wen Ni, Founder and CEO, NVI Therapeutics, and a participant in CIP notes, "As a new pharmaceutical company, there are many aspects where you need consulting support. For instance, navigating regulations and conducting pre-clinical studies require expert assistance. Charles River is a leading contract development and manufacturing organization (CDMO) and their support is invaluable. I look forward to utilizing it to guide my company through the entire process." Cell and Gene Therapy CDMO SolutionsCharles River has significantly broadened its cell and gene therapy portfolio with several acquisitions and expansions to simplify complex supply chains and meet growing demand for plasmid DNA, viral vector, and cell therapy services. Combined with the Company's legacy discovery, safety, and testing capabilities, Charles River offers an industry-leading "concept to cure" advanced therapies solution. Bringing together subject matter experts, executives, investors, and thought leaders in the CGT space to discuss and navigate critical challenges, register for the European Cell & Gene Therapy Summit 2025 in London on September 16: About Charles RiverCharles River provides essential products and services to help pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe accelerate their research and drug development efforts. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them. To learn more about our unique portfolio and breadth of services, visit About BioTech Social Social Inc. (BSI) develops financing tools that expand access to capital for biotech, med-tech, pharma-tech, diagnostic, digital health, and other life science companies. BSI is the parent company of BioTech Funding Portal ( an SEC registered funding portal and member of FINRA that offers accredited and non-accredited investors opportunities in life science companies under Regulation Crowdfunding. This is not an investment solicitation and investing involves the risk of loss. Learn more at View source version on Contacts Charles River Investor Contact:Todd SpencerCorporate Vice President,Investor Charles River Media Contact: Amy CianciarusoCorporate Senior Vice President,Chief Communications
Yahoo
05-07-2025
- Entertainment
- Yahoo
Fourth of July fireworks in Boston: 2025 start time, how to watch
Independence Day is nearly here, and Americans around the country are making plans to celebrate the United States' 249th birthday. Booming fireworks, patriotic parades and outdoor barbecues have become annual traditions, and many employees enjoy the day off from work for the federal holiday. The Fourth of July marks the day the Declaration of Independence was adopted and the 13 North American colonies officially separated from Great Britain. Widely considered the "birthplace" of the American Revolution, Boston holds the annual Boston Pops Fireworks Spectacular, which has been running for decades. Here's what you need to know about Fourth of July fireworks and celebrations in Boston. This year, the Boston Pops Fireworks Spectacular will be on Friday, July 4. The concert is schedule to begin at 7 p.m. and the fireworks will start at 9:40 p.m. The show takes place on the Charles River Esplanade between the Longfellow and Massachusetts Avenue Bridges at the DCR Hatch Shell, located at 47 David G. Mugar Way in Boston. Those who can't make the fireworks spectacular in person can catch the show on live TV, airing locally on WHDH from 7-10 p.m. and nationally on The CW Network from 9-10 p.m. Contributing: Bailey Allen, USA TODAY NETWORK - New England Fernando Cervantes Jr. is a trending news reporter for USA TODAY. Reach him at and follow him on X @fern_cerv_. This article originally appeared on USA TODAY: Boston Fourth of July fireworks: Start time, how to watch
CBS News
04-07-2025
- Entertainment
- CBS News
Crowds get their spots on the Esplanade for the Boston Pops Fireworks Spectacular
It was a mad dash to the Hatch Shell on July 4th as people rushed to claim their space for the annual Boston Pops Fireworks Spectacular on the Charles River Esplanade. "We got here at 7 a.m. yesterday," said a woman who came all the way from Wareham. Her group was first in line and got a spot up front for the show. People arrive early for good spot on Esplanade The July 4th fireworks and concert in Boston is recognized around the country as one of the biggest celebrations of America's independence. For so many people, it's become a family tradition. "The most important part of it is being with the people that you're with," said John Bonaccorso, who arrived early. "It's a whole day and not just the concert, it's a whole day. It is just amazing." "It's like a family here and all day just hanging out and the laughs," said another spectator. 30th year for conductor Keith Lockhart Boston Pops conductor Keith Lockhart greeted and took selfies with fans earlier in the day. This is his 30th year conducting the July 4th performance. "It's amazing, it's hard to believe that that much time has passed. To think about it, it's almost half of my life," said Lockhart. "And when I think back about the 30 years, so many amazing memories, such an ongoing privilege to be able to stand in the middle of the center of all this and share it with the people of Boston and beyond." All throughout the day, people were enjoying the festive atmosphere, delicious food and creating memories. Edward Fagan arrived early to make sure his family got a good seat for the show and fireworks. "Beautiful day to celebrate America," said Fagan. "Because we are from the West Indies and come to America to have the American dream." This year's Pops performance will feature several guest performers including LeAnn Rimes, Leslie Odom Jr. and Boston's own Bell Biv DeVoe. "Looking to hear it all and then see it all and be a part of the fireworks, entertainment and all of that good stuff and mixing with all of these wonderful people and just enjoy," said Andrea DeCosta, who arrived early to get a good spot.
