Latest news with #ChrisPearson
Yahoo
27-05-2025
- Business
- Yahoo
Terumo Interventional Systems Announces Commercial Availability of Its ROADSAVER™ Carotid Stent System
– Innovative, dual-layer micromesh, closed-cell stent with the flexibility of an open-cell stent for maximizing clinical outcomes in carotid artery stenting procedures – SOMERSET, N.J., May 27, 2025 /PRNewswire/ -- Terumo Interventional Systems (TIS), a division of Terumo Corporation, is pleased to announce the early commercial availability of its FDA-approved ROADSAVER™ Carotid Stent System. Indicated for use with the Nanoparasol® Embolic Protection System, ROADSAVER Stent System addresses carotid artery stenosis in patients with increased risk of adverse events following carotid endarterectomy. ROADSAVER Stent System is the only carotid artery stenting (CAS) device with an innovative, dual-layer micromesh. It is designed as a closed-cell stent with the flexibility of an open-cell stent, providing increased flexibility and wall apposition in complex anatomies. It is also the first dual-layer micromesh carotid stent approved in the United States, and the only carotid stent system designed to contain plaque to the vessel wall and prevent plaque protrusion, protecting against distal embolization. Available in sizes from 5 to 10 mm in width and 22 to 47 mm in length, ROADSAVER Stent System has a rapid-exchange shaft length of 143 cm. It is also fully re-sheathable and repositionable – even after 50% of the stent's length is deployed. Another important feature is the product's low-profile 5Fr design, which enhances its crossability. "ROADSAVER Stent System is yet another example of our unrelenting pursuit of achieving better outcomes for patients," said Chris Pearson, Executive Vice President – US Commercial Operations, Terumo Interventional Systems. "Its rapid delivery and accurate placement drive procedure predictability and efficiency, differentiating it from other carotid artery stents on the market and providing a level of confidence unmatched in the industry." "An inner micromesh layer with a pore size four-times smaller than any carotid stent which provides sustained embolic protection makes the ROADSAVER Stent System a leading technology in the evolution of CAS," said Michael J. Martinelli, MD, FACC, FSCAI and Chief Medical Officer, Terumo Medical Corporation. "This is supported by the results of clinical trials, which demonstrated that using ROADSAVER for symptomatic patients with high-risk lesions is safe and effective, with a low complication rate." Limited market release of the ROADSAVER Carotid Stent System is planned for summer 2025, with full market release anticipated in fall 2025. About Terumo Interventional Systems Terumo Interventional Systems (TIS), a division of Terumo Corporation, is a market leader in minimally invasive entry site management, lesion access, and therapeutic intervention. TIS offers a complete, solution-based product portfolio used in advanced coronary, peripheral and endovascular treatments with strategic initiatives in Transradial Access, Complex Coronary Intervention, Peripheral Artery Disease and Embolotherapy. TIS combines innovative research and development with a deep market understanding to create a pipeline of industry-leading devices that deliver clinical value, economic benefit, and enhanced patient outcomes. About Terumo Terumo (TSE:4543) is a global leader in medical technology and has been committed to "Contributing to Society through Healthcare" for over 100 years. Based in Tokyo and operating globally, Terumo employs more than 30,000 associates worldwide to provide innovative medical solutions in more than 160 countries and regions. The company started as a Japanese thermometer manufacturer and has been supporting healthcare ever since. Now, its extensive business portfolio ranges from vascular intervention and cardio-surgical solutions, blood transfusion and cell therapy technology, to medical products essential for daily clinical practice such as transfusion systems, diabetes care, and peritoneal dialysis treatments. Terumo will further strive to be of value to patients, medical professionals, and society at large. More information can be found at ROADSAVERINDICATIONS FOR USE The Roadsaver Carotid Stent System, when used in conjunction with the Nanoparasol Embolic Protection System (EPS), is indicated for the treatment of carotid artery stenosis in patients with elevated risk for adverse events following carotid endarterectomy and meet the criteria outlined below: Patients who have either de novo atherosclerotic or post endarterectomy restenotic lesion(s) in the internal carotid arteries or at the carotid bifurcation with ≥50% stenosis if symptomatic or ≥80% stenosis if asymptomatic (both defined by angiography),AND Patients having a vessel with reference diameters between 3.5 mm and 9.0 mm at the target lesion. CONTRAINDICATIONS The Roadsaver Carotid Stent System is contraindicated for use in: Patients in whom anticoagulant, antiplatelet therapy or thrombolytic drugs are contraindicated Patients with known hypersensitivity to nickel-titanium Patients with severe vascular tortuosity or anatomy that would preclude the safe introduction of a guide catheter, sheath, embolic protection system, or stent system Patients with uncorrected bleeding disorders Lesions in the ostium of the common carotid artery Carotid vessel with <25mm gap between the target location of the distal end of the stent and the proximal end of the distal protection device. NANOPARASOL EPSINDICATIONS FOR USE The Nanoparasol EPS is indicated for use as a guidewire to contain and remove embolic material (thrombus/debris) while performing angioplasty and stenting procedures in carotid arteries. The diameter of the artery at the site of the filter placement should be between 3.0 and 6.5 mm. CONTRAINDICATIONS The Nanoparasol EPS is contraindicated for use in: Patients in whom anticoagulant, antiplatelet therapy or thrombolytic drugs is contraindicated Patients with known hypersensitivity to nickel-titanium Patients with severe vascular tortuosity or anatomy that would preclude the landing zone requirement or the safe introduction of a guide wire, guide catheter, introducer sheath, an embolic protection device, delivery catheter, or retrieval catheter Patients with uncorrected bleeding disorders Lesions in the ostium of the common carotid artery RX ONLY. Refer to the product labels and package insert for complete contraindications, warnings, precautions, potential complications, and instructions for use. Manufacturer: Terumo Neuro, 35 Enterprise, Aliso Viejo, CA 92656, USA Distributed by Terumo Medical Corporation, 265 Davidson Ave, Somerset, NJ 08873, USA ©2025 Terumo Medical Corporation. All brand names are trademarks or registered trademarks owned by TERUMO CORPORATION, its affiliates, or unrelated third parties. View original content to download multimedia: SOURCE Terumo Interventional Systems Sign in to access your portfolio
Yahoo
17-04-2025
- Science
- Yahoo
Vast swarms of hidden galaxies may be secretly bathing the universe in a soft glow
When you buy through links on our articles, Future and its syndication partners may earn a commission. A secret population of hidden galaxies suffusing the universe in a soft glow of far-infrared light have been strongly suggested to exist, based on careful detective work into some of the most unique data to come from Europe's Herschel Space Observatory. The galaxies, if they are real, are not necessarily a surprise. The cosmos is filled with light across all wavelengths — it's just that the far-infrared component seems to be stronger than can be accounted for by all the galaxies we can see in visible light. In other words, there must be something else in the universe producing its glow. Far-infrared light, associated with longer wavelengths than what even the James Webb Space Telescope can see, is emitted by cosmic dust that has absorbed starlight. Cosmic dust is produced by the cycle of star birth and death. Dust condenses around newly formed stars — it's what planets like Earth are built out of, after all — and then is produced in huge quantities when stars die. The more intense the star formation, the more rapid the cycle of star birth and death. And the more rapid the cycle, the more dust is produced. Eventually, enough dust can be produced to literally hide the stars within a galaxy. This has led astronomers to wonder whether there are countless galaxies out there shrouded in dust —- galaxies that are quietly contributing to the far-infrared background of the cosmos. The trouble is, nobody had seen them —until possibly now. "The cosmic infrared background is like a jigsaw puzzle, but there are some pieces missing," Chris Pearson, an astronomer at the U.K.'s Rutherford Appleton Laboratory, told "We've always known that we need something to complete the puzzle, but we haven't really known what shape or form those missing pieces were going to be." Pearson led a team who used archival data from the Herschel Space Observatory to search for these missing pieces. Herschel, which was capable of viewing the universe in long wavelengths of far-infrared light, ended its mission all the way back in 2013. However, as a member of Herschel's original instrumentation team, Pearson knew of some observations that hadn't been available to regular astronomers. One of Herschel's primary instruments was SPIRE, the Spectral and Photometric Imaging Receiver. To ensure that SPIRE remained calibrated correctly, it was pointed towards a barren patch of sky just 3.5 degrees from the North Ecliptic Pole once or twice a month. "By looking at the same area of sky we always expected to get roughly the same result, and if we didn't, if we saw a systematic drift over time such as everything getting bright each month, then that would be indicative of some change in the characteristics of SPIRE, and we'd have to create a calibration correction," Pearson said. SPIRE imaged this "dark field" 141 times, but because it was only used by the instrument team to monitor the equipment itself, the dark field images were not released to the general astronomical community. However, Pearson's team realized that the images could be useful for more than just calibrating SPIRE. They stacked the 141 images — astro-imaging parlance for adding and merging the images on top of one another, which dramatically increases the signal-to-noise ratio — and threw in some data from NASA's Spitzer Space Telescope to create the deepest far-infrared view of the cosmos ever made. In this "dark field," they identified 1,848 sources of far-infrared emission. Now, the problem with observations at long wavelengths is resolution: you just don't get sharp images like you do with the Hubble or James Webb space telescopes. Even though Herschel's mirror, was larger than Hubble's, at 3.5-meters (11.5 feet) in diameter, to Herschel, the 1,848 far-infrared sources all look like amorphous blobs. Therefore, a careful statistical analysis had to be undertaken to figure out what these blobs actually are, and whether they match typical galaxy distributions. The conclusion is that they are dusty, star-forming galaxies at a range of distances from us; they are hard to find because they are faint, probably indicating that these are not large galaxies, but rather smaller dwarf galaxies undergoing their first intense bursts of star formation. If one were to extrapolate the findings all across the sky, the result would be an awful lot of small, dusty, star-forming galaxies that collectively contribute a significant fraction of the far-infrared background, and of the overall energy budget of the universe. Still, it's not necessarily the first time that some of these galaxies have been seen; they may have turned up in deep images taken by Hubble or the JWST, for example. "But it's making the link between what you see at one wavelength and what you see at another wavelength that's the problem, and again it's down to resolution," Pearson said. For example, an optical image taken by Hubble might show a cluster of individual galaxies, but in the Herschel image they would appear as just one blob of infrared light. "You don't know how many of those galaxies that you see at optical wavelengths are actually also contributing to the emission of this blob," Pearson said. What's needed is more data to fill the gaps and confirm that this population of hidden galaxies is real. That data will not be forthcoming from Herschel, though: "We've pushed what Herschel could do right to the limit with this," Pearson said. On the bright side, there are two other possibilities. One option is to conduct observations at submillimeter radio wavelengths, which is the next waveband up from far-infrared. Although the North Ecliptic Pole is not viewable from the Atacama Large Millimeter/submillimeter Array (ALMA) in Chile, Pearson's team does have some observing time coming up on the Submillimeter Array (SMA) in Hawaii, which can see the dark field. Beyond that, Pearson is a member of a consortium behind a proposed NASA mission called PRIMA, the Probe far-Infrared Mission for Astrophysics. PRIMA has made it to the final shortlist for NASA's next billion-dollar Probe class mission, competing against one other mission, the Advanced X-ray Imaging Satellite (AXiS). Final selection takes place in 2026. Related Stories: — Record-breaking 'dead' galaxy discovered by JWST lived fast and died young in the early universe — Is our universe trapped inside a black hole? This James Webb Space Telescope discovery might blow your mind — James Webb Space Telescope sees early galaxies defying 'cosmic rulebook' of star formation If PRIMA does go ahead, its telescope mirror will actually be quite a lot smaller than Herschel's at just 1.8-meters (6 feet). "So in terms of taking pictures, it won't help us because they're still going to be blurry," Pearson said. What PRIMA will specialize in is spectroscopy, breaking down the infrared light into individual wavelengths to learn more about the constituents of these galaxies, how much star formation is taking place and how far away they are. As Pearson said,, "If PRIMA goes ahead, it's going to be absolutely instrumental in solving this." Two papers describing the results, one with Pearson as the lead author and another led by Thomas Varnish of the Massachusetts Institute of Technology, were published on April 9 in the journal Monthly Notices of the Royal Astronomical Society.
