Latest news with #CityOfHope
Medscape
3 days ago
- Health
- Medscape
Prevention, Screening, Treatment: Impact on Cancer Deaths
This transcript has been edited for clarity. Hello. I'm Dr Maurie Markman from City of Hope, and I'd like to discuss a very important study. I think many of you may have heard about this, but it's important to emphasize what these investigators reported in terms of the impact of what we are doing in the cancer world today and, in my opinion, what the focus needs to be on in the future. The paper I'm referring to is "Estimation of Cancer Deaths Averted From Prevention, Screening, and Treatment Efforts, 1975-2020," published in JAMA Oncology . This was a very interesting effort; there was modeling done, and assumptions were made, in order to do what these investigators did. But this is, I think, very high-quality and reasonable data science. The paper outlines the assumptions made in coming to the conclusions reached by these investigators. They looked at breast, cervix, colorectal, lung, and prostate cancers — obviously, major cancers — and specifically looked at what the impact has been over the past 45 years of these three different strategies in averting deaths: prevention, screening, and actual treatment. The bottom line, as reported by these investigators, is that over this 45-year period, 5.94 million deaths have been averted in these five cancers combined, due to the efforts of countless numbers of individuals, researchers, clinicians, public health officials, government regulators, etc. It's an incredible and an enormously positive contribution to society and to individual patient health. They note, and this is a powerful message, that 8 of the 10 deaths, 80%, that had been averted were due to efforts in cancer prevention and screening. It may come as a surprise to some, but not to all, because of our often very intense focus and money spent on treatments for established and advanced cancers over the past decades. There's no intent either in this paper or by me to denigrate — in any way, shape, or form — the enormous efforts that have been made in treatment. But if you look at the question of deaths averted, the vast majority have come from prevention and screening efforts. And clearly, there's cost involved in these efforts, but far less than that associated with development of treatments. They're even more specific in this paper: Screening, according to these investigators, has been responsible for essentially all reduction in cervix cancer, which we certainly know from the enormous contributions of the Pap smear screening and now HPV screening: 25% of breast cancer deaths were averted due to screening; 56% from prostate cancer; 79% of deaths from colorectal cancer; and, of course, from lung cancer, 98% of the impacts on cancer deaths has resulted from a reduction in smoking. So, overall a tremendous impact, a positive impact. So many individuals and organizations avert deaths, but it's critical to remember the role of prevention and screening. And as we move forward to the future, as we look at the epidemic we have of obesity in this country and the concern about the risk of alcohol on the risk for cancer, it is important to remember the critical role to the present but also for the future of prevention and screening. Thank you for your attention.
Yahoo
12-07-2025
- General
- Yahoo
From the Archives: July 12 in the Pioneer
Jul. 12—July 12, 2015 — The theme of this year's Beltrami County Relay for Life was "City of Hope" and more than 30 teams and 350 people were expected to participate in Saturday's events at the Sanford Center. Organizers said that more than $50,000 had been raised earlier in the week, with a goal of $100,000. July 12, 2000 — Laporte received over $2 million in federal loans and grants from the U.S. Department of Agriculture, the Minnesota Pollution Control Agency and the Minnesota Department of Trade and Economic Development to replace individual wells and septic tanks with city water and sewer due to contamination. July 12, 1975 — Area residents are set to show appreciation for the contributions Mable Sattgast made to Bemidji at an upcoming reception. Since coming to town in 1959, she has started a self-help housing project, served as president of the League of Women Voters and was named Senior Citizen of Beltrami County. July 12, 1925 — The circus in Bemidji today featured a splendid collection of animals including baby tigers, "Prince" tiger mascot of Princeton University and the "Tarzan of the Apes" lions of the motion picture. Other trained animals include polar bears, llama, pigs, elephants, seals and the largest group of horses in the world.
Medscape
23-06-2025
- Health
- Medscape
Clinical Advances in Multiple Myeloma From ASCO 2025
The coming of age of chimeric antigen receptor (CAR) T-cell therapy, the selection of postinduction therapy on the basis of residual disease activity, and a novel drug delivery system are among the developments in multiple myeloma (MM) presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting. Dr Joseph Mikhael, from City of Hope Cancer Center in Phoenix, Arizona, opens with long-term follow-up data from the CARTITUDE-1 trial of ciltacabtagene autoleucel CAR T-cell therapy in heavily pretreated relapsed/refractory MM. One third of patients remained progression free for 5 or more years following a single infusion, offering hope of a cure. Next, he discusses the MIDAS trial of newly diagnosed MM, in which the treatment choice was driven by residual disease activity after induction therapy. The results indicated that autologous stem cell transplant may not be beneficial in patients with no residual disease activity and could potentially be avoided. Dr Mikhael then turns to follow-up from PERSEUS, again in newly diagnosed disease. The data showed daratumumab to be a key component of both induction therapy when combined with bortezomib, lenalidomide, dexamethasone, and maintenance therapy in combination with lenalidomide. In closing, he discusses a German trial that underlined the importance of aggressive treatment in high-risk newly diagnosed MM as well as an analysis of an on-body delivery system for subcutaneous isatuximab that met with patient satisfaction.
Daily Mail
04-06-2025
- Entertainment
- Daily Mail
EXCLUSIVE Kathie Lee Gifford fights back tears as she makes heartbreaking comment about her mortality after multiple health battles
Kathie Lee Gifford was overcome with emotion as she claimed her time is running out, weeks after opening up about enduring a 'really, really tough three years.' The 71-year-old talked about her mortality at City of Hope's Spirit of Life Luncheon on Tuesday where she presented an award to her former Today show costar, Jill Martin. Gifford, who had a hip replacement last year, was helped on stage at NYC 's Plaza Hotel by Martin, 49, at the behest of her 'personal therapist's orders.' Gifford paid tribute to her close friend, who was diagnosed with breast cancer two years ago, describing her as 'one of my favorite people on the entire planet' - and the only person who could make her return to New York from her home in Tennessee. 'Over the years, our friendship has deepened us,' she said. 'Many do, if you are blessed. And honestly, I think about Jill and I smile even when she was going through her journey and she still is. We would get on the phone together and we pray and we'd laugh. I thank her for what she was doing for others.' From A-list scandals and red carpet mishaps to exclusive pictures and viral moments, subscribe to the DailyMail's new Showbiz newsletter to stay in the loop. Gifford urged the people inside the ballroom to 'be there for people' and 'whatever their journey is because it might change the next day.' Her voice then trembled and she fought back tears as she addressed her own life. 'So when I say that Jill will be my friend for life, I mean it,' she said. 'She will be there for me and I will be there for her. 'I'll probably go a lot sooner. In fact, tick-tock, I better get off the stage.' Gifford then laughed as she wrapped up her speech and let Martin take the stage. As the entrepreneur accepted the Spirit of Life Award, Gifford was assisted down the stairs. The former host of Live! with Regis and Kathie Lee has faced a number of health challenges in recent years. In June 2024, she underwent a 'serious' and 'total' hip replacement surgery that left her in 'agonizing pain.' During her recovery, she fractured her pelvis in two places after a freak fall at her home which left her hospitalized for over a week. Speaking recently to OK! magazine, about her health setbacks she said: 'I've had a really, really tough last three years with parts of my body that have just worn out because I did so much in my life. 'I had my hip replaced, I had my shoulder done - that was from an old injury that finally got so bad, I couldn't ignore it anymore. Yet my health is perfect! I am crumbling!' Meanwhile, 'friend for life' Martin is embracing being 'cancer free,' two years after being diagnosed with stage 2 breast cancer. In an exclusive interview with Martin said: 'I'm cancer free. I am on two [chemotherapy] safety net pills, which I call my best friends and I thank them every day because they're an important part of my treatment. 'But life is different. Life will be calendarized before and after. There's a lot of beautiful things that came out of it and magical things and things I learned about myself and then devastation. 'Kathie is one of the people who taught me about being able to hold opposing things at the same time and so you can be super happy and super sad, and so that's how I feel today.' Gifford added: 'You can mourn and rejoice at the same time. That's what happened when I found my husband after his massive heart attack. I knew he saw Jesus and Jesus took his breath away so I knew exactly where he was. 'People can say, you know, you can look at something as a loss or you can look at what you still have and rejoice. It's the glimmers [in life].' Gifford's ex-husband, Frank Gifford, died in August 2015 at his Connecticut home. He was 84. His family later disclosed that he had been diagnosed with chronic traumatic encephalopathy (CTE), which is a progressive, degenerative brain disease. Martin said she hopes to 'save at least one life today' by urging people to get their regular exams and informing guests that 'one in 400 of the general population test positive for the BRCA mutation, which gives you a 60 to 90 percent chance of getting breast cancer.' Tuesday's luncheon was attended by other socialites including Howard Stern's wife Beth Stern and Fox 5's Good Day New York anchor Rosanna Scotto.
Medscape
21-05-2025
- Health
- Medscape
AI in Healthcare Faces Growing Skepticism Among Patients
This transcript has been edited for clarity. Hello. I'm Dr Markman, from City of Hope. I'd like to briefly discuss two separate but related articles that recently appeared, which touch on the evolving and critically important topic of artificial intelligence. The first paper is 'Patients' Trust in Health Systems to Use Artificial Intelligence.'The second paper is 'Public Attitudes Toward Notification of Use of Artificial Intelligence in Health Care.' Both of these manuscripts were published in JAMA Network Open . In both cases, the studies were surveys of US adults from the National Opinion Research Center. The first study was from June to July 2023. There were 2039 respondents (51% female) and very reasonable representation based upon various ethnic subgroups. The general trust in the healthcare system was asked of this group. On a scale of 0 to 12, the mean score was 5.38. This is already telling you that perhaps there may be a bit of a concern here. Now, turning to the question that we're highlighting here, which is about trust in the system to use AI responsibly. I'm going to say this and repeat it: 65.8% had low levels of trust in the healthcare system to use AI responsibly — 65.8%. Two out of three patients said they had low levels of trust in the system to use AI responsibly. This is, in my opinion, a really serious statement about how the public is viewing the situation. Furthermore, 57.7% had low levels of trust in their healthcare system to be sure that AI would not harm them — more than half said they had a low level of trust that their system would make sure that AI would not harm them. This isvery concerning. In the second study, there were 2021 respondents; a slight majority, 52%, were female. There was a statement posed: 'It is important that I am notified about the use of AI in my healthcare.' The question was, "How important is that statement?" and 62.7% of respondents said — and this is the highest level — it was very true that they wanted to be notified if AI was being used in their healthcare. Only 4.8%, or 1 out of 20 patients, said they didn't want to be notified. Clearly, patients want to know it's being used and they don't want it to be used without their knowledge. Second, they are fearful and concerned. I think all members of the healthcare environment, including doctors, nurses, healthcare administrators, and payers, need to listen to this. The public is concerned, based upon what they've read, what they've heard, podcasts they've listened to, and social media. They're concerned about the potential risk of harm, and they don't necessarily trust their own healthcare system to do what's best for them. It's a critical message that needs to be heard. I actually agree with the opinion of the majority of the public about that potential concern. Thank you for your attention.
