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Less water, more rice: Why gene editing may be a game changer
Less water, more rice: Why gene editing may be a game changer

Time of India

time20-05-2025

  • Science
  • Time of India

Less water, more rice: Why gene editing may be a game changer

Less water, more rice: Why gene editing may be a game changer TOI Explains Vishwa Mohan TNN May 20, 2025, 18:34 IST IST With drought-tolerant, climate-resilient rice just two years away from Indian farms, gene editing could change how the country grows its staple. But questions around safety, regulation, and adoption still remain Two varieties of rice — 'DRR Dhan 100 (Kamala)' and 'Pusa DST Rice 1', developed by the Indian Council of Agricultural Research ( ICAR ) and its institutes — are the world's first genome-edited varieties, and promise to be a gamechanger in sustainable agriculture .

Less water, more rice: Why gene editing of rice may be a game changer
Less water, more rice: Why gene editing of rice may be a game changer

Time of India

time19-05-2025

  • Science
  • Time of India

Less water, more rice: Why gene editing of rice may be a game changer

Two varieties of rice - 'DRR Dhan 100 (Kamala)' and 'Pusa DST Rice 1', developed by ICAR and its institutes - are the world's first genome-edited varieties, and promise to be a game-changer in sustainable agriculture . Scientists say these two varieties, when cultivated on 5 million hectares, can produce 4.5 million tonnes of additional paddy and save a total of 7,500 million cubic metres of irrigation water. And, apart from a yield advantage of 20%-30%, these climate-resilient varieties could reduce methane emissions by 20%, the scientists claim. This could go a long way towards solving one of the biggest problems in cultivating rice, a staple for about 800 million Indians: its resource-heaviness. Each kilo of traditional rice requires, on average, 2,500 litres of water, and its cultivation consumes more than 50% of the irrigation water available to the country's agriculture sector. Genome editing enables scientists to make targeted changes in the native genes of living organisms, creating new and desirable traits without introducing foreign DNA. It involves adding, removing or modifying DNA sequences at specific locations in the genome. This technology has applications in various fields, including medicine, agriculture and basic research. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like 복부비만 원인 "오래되고 딱딱한 묵은 지방" 간단히 녹이는 방법 남재현 체지방 다이어트 더 알아보기 Undo Because rice is such a resource-guzzler, ICAR's National Rice Research Institute (NRRI), which scientifically calculated the amount of water needed to produce 1kg of rice, noted that a major impact of climate change would be visible in the form of water stress, and that rice cultivation was likely to be most affected. "In the next two decades, there's a need to produce around 25% more from 10%-15% reduced share of water," said ICAR-NRRI in a research paper on managing water for rice-production systems. Genome editing allows the development of drought-tolerant rice varieties that have a low water requirement. ICAR (Indian Council of Agricultural Research) had launched a genome-editing research project in rice in 2018 and selected two widely cultivated mega rice varieties - 'Samba Mahsuri (BPT5204)' and 'MTU1010 (Cottondora Sannalu)' - to enhance their qualities through tech interventions. Scientists enhanced these rice varieties with better stress tolerance, improved yield and climate adaptability without compromising on their existing strengths as they developed the two new genome-edited varieties. Genome-edited varieties are, however, suitable for only those states/UTs for which the parent varieties are recommended: Tamil Nadu, Karnaktaka, Puducherry, Chhattisgarh, Andhra Pradesh, Telangana, Odisha, Maharashtra, Kerala, Madhya Pradesh, Bengal, Bihar, Jharkhand and (eastern) UP. ICAR is now accessing intellectual property rights before the newly developed genome-edited varieties are made available to farmers. Seeds for commercial cultivation are expected to reach farmers within two years. The Coalition for a GM-Free India - a network of organisations and individuals advocating for a GM-free India - has demanded that govt immediately withdraw the two genome-edited rice varieties and bring them under the purview of rigorous regulation. They claim the two varieties have the potential to harm humans and cause irreversible damage to the environment, apart from threatening the country's seed sovereignty. Since the genome-edited line contains no foreign DNA, it makes it comparable to conventionally bred varieties. Two key approaches - Site Directed Nuclease 1 (SDN1) and Site Directed Nuclease 2 (SDN2) - produce genetically edited organisms that are considered "indistinguishable from naturally occurring or conventionally bred mutants". As such, they are exempt from stringent bio-safety regulations under Rules 7-11 of the Environment (Protection) Act, 1986. The Institutional Bio-safety Committee (IBC) of ICAR institutes approved the lines, and the Review Committee on Genetic Manipulation (RCGM) granted clearance on May 31, 2023, for classification under India's relaxed regulatory framework for SDN1 and SDN2 genome edits. Viswanathan Chinnusamy, lead developer of the genome-edited rice and joint director (research), IARI, said plants with genome-edited seed varieties do not contain 'exogenous' (foreign) DNA, unlike genetically modified crops. He also dispelled health fears with gene-edited rice varieties, saying the genome-edited variety is equivalent to a mutant variety developed by a conventional approach. "Hence, it has no health or environmental concerns," he said.

Recipe with science, sentiment and rice
Recipe with science, sentiment and rice

New Indian Express

time15-05-2025

  • Science
  • New Indian Express

Recipe with science, sentiment and rice

In the world of rice breeding, few stories bloom as beautifully as Kamala's. Born not just in the lab but in the heart of a grieving son, Kamala — the world's first genome-edited rice variety — is both a scientific triumph and a tribute. Dr Satendra Kumar Mangrauthia, the principal scientist at the Indian Institute of Rice Research (IIRR), Rajendranagar, and his team developed DRR Dhan 100 — popularly known as Kamala — entirely in India using cutting-edge genome editing. Kamala promises higher yields, stronger stems and sustainability — all without foreign DNA. As India joins the US and Japan in this breakthrough, Dr Mangrauthia, in a conversation with TNIE's Adeena A, discusses the significance of this innovation and its potential to transform Indian agriculture. Excerpts What makes Kamala unique? DRR Dhan 100, or Kamala, is the first rice variety in the world developed using genome-editing technology. This cutting-edge method allows for precise crop improvement, making Kamala a milestone in rice breeding. While the US and Japan have commercialised genome-edited crops, India has become the third country to apply this technology specifically to rice. Why the name 'Kamala'? Kamala is named in memory of my late mother. Losing her was one of the most painful moments of my life, and since then, I've dedicated all my work to her. Naming this variety Kamala is a heartfelt tribute to her love and support.

How did India develop genome edited rice?
How did India develop genome edited rice?

The Hindu

time15-05-2025

  • Science
  • The Hindu

How did India develop genome edited rice?

The story so far: Union Agriculture Minister Shivraj Singh Chouhan recently announced that India has become the first country in the world to develop rice varieties using genome editing technology. The new seeds will be available for farmers after the required clearances within six months and large-scale seed production will probably take place during the next three crop seasons. What are the new varieties? A team of researchers from various institutions, guided by the Indian Council of Agricultural Research (ICAR), were behind the development of the two varieties — the DRR Dhan 100, also known as Kamala, which was developed from a popular high yielding green rice Samba Mahsuri, and Pusa DST Rice 1, which was developed from the Maruteru 1010 (MTU1010) variety. What are its peculiarities? According to the ICAR, the increase in food demand, challenges posed by climate change and increasing biotic and abiotic stresses such as pest attacks and scarcity of water, led to the development of high yielding, climate resilient and nutritionally rich crop varieties. Kamala has shown superior yield, drought tolerance, high nitrogen use efficiency and 20 days earliness over its parent variety. It has an average yield of 5.37 tonnes per hectare against the 4.5 tonnes per hectare of Samba Mahsuri across two years and 25 locations of testing in the country. 'The earliness trait will help in saving water, fertilizers, and reduced emission of methane,' the ICAR said. The second variety, Pusa DST Rice 1, has a yield of 3,508 kilograms per hectare (a capacity of 9.66% more) over the parent rice variety, MTU 1010, which has an average yield of 3,199 kg per hectare under 'inland salinity stress'. It also showed a superiority of 14.66% over the MTU 1010 under alkalinity conditions, and a 30.4% yield advantage under coastal salinity stress. What was the technology used? According to Joint Director (Research), Indian Agricultural Research Institute, Viswanathan. C, scientists have used Site-Directed Nuclease 1 and Site-Directed Nuclease 2 (SDN-1 and SDN-2) genome editing techniques to develop the seeds. Though this technique was used to develop different crops since 2001, such as tomatoes, a fish variety in Japan and a soybean variety in the U.S., making a rice variety has been done for the first time. In 2020, the first peer-reviewed research paper on Pusa DST Rice 1 was published, which got cited in more than 300 papers since then. The paper on Kamala is in the stage of publication. 'The international research community has approved both the varieties,' Dr. Viswanathan said. Are they GM crops? Dr. Viswanathan says that since the genome editing technology SDN-3 is not involved in this process, they are not genetically modified (GM) crops. In the SDN-1 approach, scientists make a cut and the repair is done automatically while in SDN-2, scientists give guidance to the cell to do the repair and the cell copies it. In SDN-3, however, scientists introduce a foreign gene from other varieties and integrate it into the improved varieties. This process is considered as genetic modification. In this case, the mutant was developed without any foreign gene and mutation occurred through natural process. This is a precision mutation technique and several countries have exempted this process from the regulations required for developing GM crops. 'No foreign gene is there in these crops, only the native gene is there in the final product,' Dr. Viswanathan said. A team of scientists from various governmental institutions were part of this research. It was tested in the fields under the All India Coordinated Research Project on Rice during 2023 and 2024. What are the objections? Venugopal Badaravada, who was a farmers' representative in the ICAR governing body said that the ICAR's genome-edited rice claims are premature and misleading. A day after the announcement he said in a statement that farmers demand accountability, transparent data, and technologies that are tested in our fields — not just polished press releases. He was expelled from the governing body soon after this and the ICAR accused Mr. Badaravada of spreading falsehoods about the institution. The Coalition for a Genetically Modified-Free India, a group of activists who are fighting a case against GM crops in the Supreme Court, said the biotech industry and lobbies have resorted to falsely portraying gene editing as a precise and safe technology, whereas published scientific papers show that this is untrue. 'India's de-regulation of two kinds of gene editing is outright illegal,' the organisation said. They claimed that gene editing tools are proprietary technologies under Intellectual Property Rights (IPR) ownership and have a direct bearing on the seed sovereignty of the country's farming community. 'The Government of India has to reveal the situation with regard to IPRs on the released varieties transparently, immediately. The Government of India is compromising on farmers' seed sovereignty and our food sovereignty by bringing in technologies entangled in IPR issues,' they said.

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