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Pioneering Advances Reshape the Future of Live Cell Imaging
Pioneering Advances Reshape the Future of Live Cell Imaging

Time Business News

time24-07-2025

  • Health
  • Time Business News

Pioneering Advances Reshape the Future of Live Cell Imaging

Live cell imaging is a technique that is used to study living cells in real time, using advanced imaging systems such as fluorescence or confocal microscopy. This allows researchers to inspect cellular processes such as movement, division and interaction without interrupting cells. The market for live cell imaging is increasing due to increasing demand to detect early disease, increase in research in cancer and neurobiology, progress in imaging technologies and more investment in cell-based drug search. Additionally, the growth of personal medical and stem cell research is further enhancing its adoption in both academic and drug fields. Key Growth Drivers and Opportunities Increasing Demand for Detection of Early Disease: The increasing demand for initial disease detection is increasing the increase in live cell imaging market, as this technique enables the real -time view of cellular behavior, which helps researchers to identify abnormalities in early stages. In the progression of the disease, initial insight, especially in cancer, neurodegenerative, and infectious diseases, allow rapid diagnosis and more effective treatment development. It is an accurate, real -time real -time cellular data requiring, which advancing healthcare and research institutes to adopt advanced live cell is imaging systems, promoting market expansion. Challenges Live cell imaging markets face boundaries such as high equipment and maintenance costs, which can restrict adoption between small research laboratories and institutions. Additionally, the complexity of the imaging system requires efficient personnel for operation and data analysis, which is a challenge in resource-limited settings. Live imaging can also affect cell viability over time due to phototoxicity and environmental disturbances, which can affect the result accuracy. Limited standardization and fertility on platforms obstruct the extensive clinical application. Innovation and Expansion An Innovative Live-Cell Imaging System Is Unveiled by a Durham Startup In February 2025, A live-cell imaging system that greatly increases speed and throughput for cell analysis has been introduced by Ramona, a Durham-based supplier of cutting-edge imaging equipment for the life sciences. Ramona wants to raise the bar for throughput speeds and standards using Vireo. Vireo can evaluate a 96-well plate with five channels in less than two minutes, according to the firm. After a year-long early access program for research institutes, the product will be commercially released. The Neuroscience Center and the Carolina Institute for Development Disabilities are two early users at the UNC School of Medicine. For real-time cell analysis, Nanolive introduces the LIVE Cell Death Assay In September 2022, The LIVE Cell Death Assay, a push-button, automated solution for label-free cell health, death, apoptosis, and necrosis profiling, is another revolutionary instrument in the field of cell analysis from Nanolive. First-in-class cytotoxicity analysis of dynamic label-free live cell data is offered by the LIVE Cell Death Assay (LCDA). The LCDA was created with cutting-edge machine learning techniques and has been trained to distinguish between necrosis and apoptosis in addition to living and dead cells. The LCDA is designed to be as easy to use as feasible; all it takes is one button click to begin the analysis. It provides 13 indicators linked to viability and death. Inventive Sparks, Expanding Markets Prominent players working in the live cell imaging market include Thermo Fisher Scientific Inc., Revilit., Nikon Corporation Healthcare, Zes Group and others. Investing in technology innovations involves AI-operated image analysis, super-resolution microscopy, and automation to improve productivity and accuracy, one of the main initiatives for live cell imaging businesses. Business will focus on enhancing your product line by creating affordable and intuitive solutions for a series of research uses, serving both large pharmaceutical firms and small academic laboratories. About Author: Prophecy is a specialized market research, analytics, marketing and business strategy, and solutions company that offer strategic and tactical support to clients for making well-informed business decisions and to identify and achieve high value opportunities in the target business area. Also, we help our client to address business challenges and provide best possible solutions to overcome them and transform their business. TIME BUSINESS NEWS

Sizeo Announces Success in AI-Driven Inventory Optimization with Designer Brands
Sizeo Announces Success in AI-Driven Inventory Optimization with Designer Brands

Business Wire

time16-07-2025

  • Business
  • Business Wire

Sizeo Announces Success in AI-Driven Inventory Optimization with Designer Brands

BUSINESS WIRE)-- Sizeo, a Durham-based AI inventory optimization software company, is proud to announce the success of its ongoing partnership with Designer Brands Inc. (NYSE: DBI). DBI is one of North America's largest designers, producers, and retailers of footwear and accessories. Sizeo, a Durham-based AI inventory optimization software company, is proud to announce the success of its ongoing partnership with Designer Brands Inc. (NYSE: DBI). Sizeo's customers utilize the solution to automate the execution of key buying and planning decisions, drive top and bottom-line growth, and improve customer experience. Since 2022, DBI has leveraged Sizeo's technology in its U.S. DSW Designer Shoe Warehouse stores to support critical retail planning and supply chain transformation initiatives. Benefits of Sizeo's solution include: Best-in-class size profile analytics to support smarter buying and allocation at the style + size + location level. Smart store indexing to enhance localized inventory decisions and ensure customers can find the right size, in the right store, at the right time. Modern, scalable architecture that integrates seamlessly into planning, buying, and allocation workflows. 'At Designer Brands, we're always seeking innovative technologies that elevate the customer experience while improving our business fundamentals,' said Dave Berlin, Director of Stores and Corporate Systems at Designer Brands. 'Our relationship with Sizeo has never felt transactional—it's a true two-way collaboration where ideas flow in both directions.' 'We're thrilled to partner with Designer Brands,' said Gray King, CEO of Sizeo. 'DBI's operational scale and focus on measurable results make them an ideal partner. This collaboration is more than just technology deployment. It's a shared commitment to smarter inventory, higher margins, and better customer outcomes.' About Designer Brands Inc. Designer Brands is one of the world's largest designers, producers, and retailers of the most recognizable footwear brands and accessories, transforming and defining the footwear industry through a mission of being shoe obsessed. With a diversified, world-class portfolio of coveted brands, including Topo Athletic, Keds, Vince Camuto, Kelly & Katie, Jessica Simpson, Lucky Brand, Mix No. 6, Crown Vintage and others, Designer Brands designs and produces on-trend footwear and accessories for all of life's occasions delivered to the consumer through a robust direct-to-consumer omni-channel infrastructure and powerful national wholesale distribution. Powered by a billion-dollar digital commerce business across multiple domains and over 650 DSW Designer Shoe Warehouse, The Shoe Co., and Rubino stores in North America, Designer Brands delivers current, in-line footwear and accessories from the largest national brands in the industry and holds leading market share positions in key product categories across women's, men's, and kids'. About Sizeo AI Sizeo ( is the retail industry's leading size and pack optimization software. Built for enterprise apparel and footwear companies, Sizeo helps brands and retailers drive margin and efficiency by automating the complex task of getting sizing and packing right. Sizeo delivers fast time-to-value and proven ROI.

This NC city is among the safest to drive in the US, new report says
This NC city is among the safest to drive in the US, new report says

Yahoo

time09-07-2025

  • Automotive
  • Yahoo

This NC city is among the safest to drive in the US, new report says

The safest place to drive in North Carolina is a city in the Triangle, a recent report says. Allstate, a national auto insurance provider, recently released its America's Best Drivers Report for 2025, analyzing auto insurance claims data in the 200 most-populated U.S. cities. The report aimed to find the safest and riskiest cities for drivers, defining a collision as any auto crash resulting in a property or collision damage claim. First launched in 2005, this year's report also reviewed collision data from a decade ago to reveal shifts in driving safety across the country. Cary was ranked the No. 4 city with drivers least likely to experience a collision, Allstate said. Here's why the city scored so well. According to the report, drivers in Cary are 18.3% less likely to get in an accident than the national average. A driver's average time between collisions is 12.9 years in Cary, the report said. Allstate claims data shows that the average driver in the U.S. experiences a vehicle collision once every 10.56 years. North Carolina Department of Transportation data from 2023 (the latest data made available) shows Cary ranked 51st in the state in reported collisions, with 11,036 since 2020. Charlotte ranked No. 1, with 125,075 crashes during that period, followed by Raleigh with 67,782, Winston-Salem with 39,285 and Greensboro with 32,245. As of Thursday, July 3, there have been 13 documented collisions within the town in the month, according to the city crash data. Overall, Cary's ranking improved from No. 10 to No. 4, a six-position rise since 2015. According to the Allstate report, Fayetteville ranked 13th on the list, Greensboro was No. 34, and Durham was No. 40. Raleigh ranked 60th, and Charlotte finished just inside the top 100 at No. 99 in the report. Here are the 10 cities in the United States that present the most risk for drivers, according to Allstate: Boston Washington, DC Baltimore, MD Worcester, MA Springfield, MA Glendale, CA Los Angeles Oakland Providence Philadelphia Here are the 10 cities Allstate says are the safest for U.S. drivers: Brownsville, TX Boise, ID Fort Collins, CO Cary, NC Laredo, TX Olathe, KS Scottsdale, AZ Port St. Lucie, FL Madison, WI Eugene, OR 'Defensive driving is your safeguard against the unpredictable nature of the road,' Durham-based Hyland, Padilla & Fowler law firm says on its website. 'It's about being proactive rather than reactive. This means keeping a safe distance from the vehicle ahead, staying out of other drivers' blind spots, and being vigilant about the behavior of other road users.' Raleigh-based Safety Driving School advises motorists to follow this guidance to stay safe while traveling: Be familiar with North Carolina traffic laws Wear seat belts Follow posted speed limits Be prepared for North Carolina's weather conditions Drive defensively Don't drive under the influence Look out for pedestrians and cyclists Use proper lane discipline Know how to use roundabouts Maintain your vehicle properly Take driver safety courses Have a question about your community you'd like answered? Or maybe a tip or story idea you'd like to share? The service journalism teams at The News & Observer and The Charlotte Observer want to hear from you. If you have a question about the Charlotte area, send The Charlotte Observer team a question by submitting questions to this form. If you have a question about Raleigh or a Triangle area community, send The News & Observer team a question by submitting questions to this form. Is it legal for NC drivers to pass bikes on the road? What state law says How old is too old for jury duty in North Carolina? What state law says

Here are the Triangle's largest "unicorn" startups
Here are the Triangle's largest "unicorn" startups

Axios

time07-07-2025

  • Business
  • Axios

Here are the Triangle's largest "unicorn" startups

When Durham-based sports software company Teamworks revealed last month it had gained a valuation of more than $1 billion, it became the Triangle's first tech startup to join the " unicorn" club — startups surpassing a $1 billion valuation — in more than three years. Why it matters: While the early pandemic years saw an influx of cash go to startups due to low interest rates, raising money has grown significantly more difficult over the past two years. But there are signs that such investments could be picking back up, Scot Wingo, a local investor, told Axios. What they're saying: "It's whipsawing around," Wingo said of investments into startups, noting investment companies seem less concerned now about tariffs. "There is a lot of private equity deals going on, and there have been a couple high-profile IPOs that have gone well," he added. "It definitely feels like directionally we are going in the right way." Between the lines: It's been years since the Triangle had a startup go public on a stock exchange, and startups valued at more than $1 billion represent some of the region's best chances of hitting that mark. An IPO could potentially provide financial windfalls for some local employees and investors that could flow back through the local economy. Wingo said many people are watching to see how well Figma's potential IPO fares, as an encouragement for local startups like Pendo or SAS. Zoom in: There are more than 1,200 startups around the world valued at $1 billion or more, according to CB Insights. Five of them are located in the Triangle, according to data from CB Insights, Pitchbook and Crunchbase. Here are the startups in the Triangle that have fetched "unicorn" valuations: 🕹️ Epic Games: The Cary-based video game maker has a valuation of $22 billion, according to CB Insights, after raising $1.5 billion from Disney last year. The company is the 13th most valuable startup in the world, according to CB Insights, and is so large that Axios' Dan Primack suggested referring to startups of its size as "dragons" rather than unicorns. Locally, the company has a large presence in Cary, with more than 3,000 employees. However, it has withdrawn plans to build a new headquarters on the former site of Cary Towne Center. 🖥️ Pendo: The Raleigh software startup has a valuation of $2.6 billion, according to Pitchbook, and has long held ambitions of going public. The company has conducted layoffs in recent years, but remains one of the largest tech firms in Raleigh and became profitable for the first time last year. 🏈 Teamworks: Founded by a former Duke football player, Durham-based Teamworks runs a software platform that helps sports teams manage their players' schedules, nutrition and even their online brand — a feature that has become popular in the era of NIL. The company now has a valuation of $1.2 billion, according to Pitchbook, and its customers include every NFL team, most Division I college athletic departments and 90% of MLB teams. 🔐 JupiterOne: Morrisville-based JupiterOne, a maker of cybersecurity tools, has a valuation of $1 billion, according to Pitchbook. The company's founder, N.C. State grad Erkang Zheng, stepped down as CEO last year. But he is now raising money for a new AI startup, though details on the company have not yet been revealed.

Durham sports startup hits $1B valuation
Durham sports startup hits $1B valuation

Axios

time07-07-2025

  • Business
  • Axios

Durham sports startup hits $1B valuation

Teamworks, a Durham-based startup making software for professional and college sports teams, is now valued at $1 billion after raising new money from investors. Why it matters: The valuation would put Teamworks into the Triangle's small club of unicorn startups (startups with valuations of $1 billion or more) and comes at a time when funding rounds have been less plentiful than in recent years. Driving the news: Teamworks unveiled the valuation on Tuesday during a new $235 million funding round led by Dragoneer Investment Group. What it does: Founded in downtown Durham by former Duke offensive lineman Zach Maurides, Teamworks runs a software platform that helps sports teams manage their players' schedules, nutrition and even their online brand — a feature that has become popular in the era of NIL. The company says that more than 6,500 sports teams and military organizations worldwide use its software platform, including every NFL team, most Division I college athletic departments and 90% of MLB teams. The goal of the new funding round is to add more artificial intelligence-driven products using the massive amounts of data it has collected on athletes worldwide.

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