Latest news with #EELS
Yahoo
04-08-2025
- Science
- Yahoo
Groundbreaking imaging tech maps elements in frozen bio-particles with precision
Cryo-transmission electron microscopy (cryo-TEM) has transformed the way scientists study biological and organic materials. Flash-freezing samples preserves their structure in a state close to how they exist in nature. Researchers have used this technique for years to study the size, shape, and dispersion of biological matter at high resolution. But cryo-TEM has one major blind spot: it struggles to reveal elemental composition, an essential factor for understanding material function. Current solutions like energy-filtered TEM (EF-TEM) and electron energy loss spectroscopy (EELS) can detect elemental signals, but they come with drawbacks. They often cause sample damage, suffer from image drift, and have mostly been used for metals or bulk materials. Imaging beyond the structure A team at Tohoku University has now solved that limitation. They developed a new cryo-EELS/EF-TEM technique that captures both the structure and elemental makeup of samples in frozen solvents. The method allows researchers to study delicate organic nanomaterials without compromising image clarity or damaging the sample. The problem with conventional EELS imaging is two-fold: ice within the sample increases unwanted background signals, and drift during scanning causes blurred images. These issues make it hard to resolve the actual material under investigation, especially in biological or soft organic samples. To address this, the Tohoku team refined the '3-window method,' a known EELS background correction approach, tailoring it for frozen conditions. This improved background subtraction helps remove interference from the ice, making the elemental signals from the target material stand out clearly. Solving drift with new tools Drift remained a challenge during long EELS scans. To counter this, the team introduced a drift compensation system that stabilizes the image throughout data collection. They also developed a software extension for the ParallEM microscope control system. This tool automates energy shift adjustments during elemental mapping, streamlining the process. With the new method in place, the researchers successfully visualized silicon distribution in silica nanoparticles as small as 10 nanometers. The particles were suspended in frozen solvent, closely mimicking real-world biological conditions. They also tested the technique on hydroxyapatite particles, a calcium phosphate material found in bones and teeth. The method clearly revealed the distribution of calcium and phosphorus, two biologically significant elements, alongside the particles' structure. The ability to map both structure and composition at such fine resolution opens up major possibilities. This technique can now support research into biomaterials, medical implants, food technology, catalysts, and even functional inks. The findings were published in Analytical Chemistry on July 31, 2025. By overcoming the core limitations of cryo-EELS and EF-TEM, namely drift, damage, and background noise, the Tohoku University team has pushed the boundaries of what cryo-TEM can do. Researchers across disciplines now have a powerful new tool to explore nanoscale materials' hidden chemistry without losing the detail or integrity of their samples. Solve the daily Crossword
The Herald Scotland
02-05-2025
- Entertainment
- The Herald Scotland
I Kissed A Girl singer-songwriter Jill Sobule dies in house fire
John Porter, her manager, said in a statement: 'Jill Sobule was a force of nature and human rights advocate whose music is woven into our culture. Extremely sad to hear of the passing of my old friend @jillsobule. A true original. She and I wrote 'Manchild', the closing song on the first EELS album in the South of France one night when EELS wasn't even a thing yet. So long, old friend. You were so much fun to be around.E — EELS (@THE_EELS) May 2, 2025 'I was having so much fun working with her. I lost a client and a friend today. I hope her music, memory, and legacy continue to live on and inspire others.' During her more than three decades of recording, Sobule released 12 albums that addressed such complex topics as the death penalty, anorexia nervosa, reproduction and LGBTQ+ issues. Her first album, Things Here Are Different, was released in 1990. Five years later, she received widespread attention for her hit singles, Supermodel, from the movie Clueless, and I Kissed A Girl, which, despite being banned on several southern radio stations, made it into the Billboard Top 20 in the US. Oh, boy. Our dear friend @jillsobule has died. I'm really to numb to post much of anything. We loved her. She loved us. She was wonderful, brilliant, hilarious. We miss her, so much. — Lloyd Cole (@Lloyd_Cole) May 2, 2025 I Kissed A Girl has the same title as Katy Perry's 2008 worldwide hit, but they are two different songs. She also starred in an autobiographical off-Broadway musical that initially premiered at the Wild Project in New York in 2022 and includes songs and stories about her life. Sobule was known for taking control of her career by fundraising so she could make her next album. In 2008, after two major record companies dumped her and two indie labels went bankrupt beneath her, she raised tens of thousands of dollars from fans so she could make a new album. 'The old kind of paradigm, where you've always waited for other people to do things, you'd have your manager and your agent,' she said at the time. 'You'd wait for the big record company to give you money to do things and they tell you what to do. This is so great. I want to do everything like this.' Sobule was scheduled to perform in Denver on Friday night. Instead, there will be an informal gathering hosted by her friend Ron Bostwick from 105.5 The Colorado Sound at the performance space where attendees can 'share a story or song', according to her publicist. Sobule achieved fame in the 1990s thanks to her work on the movie Clueless (AP) A formal memorial to celebrate her life and legacy will be held later this summer. Craig Grossman, her booking agent, said: 'No-one made me laugh more. Her spirit and energy shall be greatly missed within the music community and beyond.' Born in Denver, Colorado, on January 16 1959, she has described herself as a shy child who preferred observing over participating. Sobule was known for playing dozens of shows a year and has described her live performances as vulnerable experiences. She said she often does not have a set list and wings it. She has performed with such icons as Neil Young, Billy Bragg and Cyndi Lauper, and also inducted Neil Diamond into the Songwriter's Hall of Fame, according to her website. She also sang a song as herself on an episode of The Simpsons in 2019. 'In a good way, I feel like I'm still a rookie,' she told The Associated Press in 2023 in an interview about her musical. 'There's so much more to do and I haven't done my best yet.' She is survived by her brother and sister-in-law, James and Mary Ellen Sobule, along with her nephews and cousins.
Leader Live
02-05-2025
- Entertainment
- Leader Live
I Kissed A Girl singer-songwriter Jill Sobule dies in house fire
Her death in Woodbury, Minnesota, was confirmed by her publicist, David Elkin. It was not immediately clear how the fire started. John Porter, her manager, said in a statement: 'Jill Sobule was a force of nature and human rights advocate whose music is woven into our culture. Extremely sad to hear of the passing of my old friend @jillsobule. A true original. She and I wrote 'Manchild', the closing song on the first EELS album in the South of France one night when EELS wasn't even a thing yet. So long, old friend. You were so much fun to be around.E — EELS (@THE_EELS) May 2, 2025 'I was having so much fun working with her. I lost a client and a friend today. I hope her music, memory, and legacy continue to live on and inspire others.' During her more than three decades of recording, Sobule released 12 albums that addressed such complex topics as the death penalty, anorexia nervosa, reproduction and LGBTQ+ issues. Her first album, Things Here Are Different, was released in 1990. Five years later, she received widespread attention for her hit singles, Supermodel, from the movie Clueless, and I Kissed A Girl, which, despite being banned on several southern radio stations, made it into the Billboard Top 20 in the US. Oh, boy. Our dear friend @jillsobule has died. I'm really to numb to post much of anything. We loved her. She loved us. She was wonderful, brilliant, hilarious. We miss her, so much. — Lloyd Cole (@Lloyd_Cole) May 2, 2025 I Kissed A Girl has the same title as Katy Perry's 2008 worldwide hit, but they are two different songs. She also starred in an autobiographical off-Broadway musical that initially premiered at the Wild Project in New York in 2022 and includes songs and stories about her life. Sobule was known for taking control of her career by fundraising so she could make her next album. In 2008, after two major record companies dumped her and two indie labels went bankrupt beneath her, she raised tens of thousands of dollars from fans so she could make a new album. 'The old kind of paradigm, where you've always waited for other people to do things, you'd have your manager and your agent,' she said at the time. 'You'd wait for the big record company to give you money to do things and they tell you what to do. This is so great. I want to do everything like this.' Sobule was scheduled to perform in Denver on Friday night. Instead, there will be an informal gathering hosted by her friend Ron Bostwick from 105.5 The Colorado Sound at the performance space where attendees can 'share a story or song', according to her publicist. A formal memorial to celebrate her life and legacy will be held later this summer. Craig Grossman, her booking agent, said: 'No-one made me laugh more. Her spirit and energy shall be greatly missed within the music community and beyond.' Born in Denver, Colorado, on January 16 1959, she has described herself as a shy child who preferred observing over participating. Sobule was known for playing dozens of shows a year and has described her live performances as vulnerable experiences. She said she often does not have a set list and wings it. She has performed with such icons as Neil Young, Billy Bragg and Cyndi Lauper, and also inducted Neil Diamond into the Songwriter's Hall of Fame, according to her website. She also sang a song as herself on an episode of The Simpsons in 2019. 'In a good way, I feel like I'm still a rookie,' she told The Associated Press in 2023 in an interview about her musical. 'There's so much more to do and I haven't done my best yet.' She is survived by her brother and sister-in-law, James and Mary Ellen Sobule, along with her nephews and cousins.
BreakingNews.ie
02-05-2025
- Entertainment
- BreakingNews.ie
I Kissed A Girl singer-songwriter Jill Sobule dies in house fire
Jill Sobule, the award-winning singer-songwriter behind I Kissed A Girl, has died in a house fire aged 66. Her death in Woodbury, Minnesota, was confirmed by her publicist, David Elkin. It was not immediately clear how the fire started. Advertisement John Porter, her manager, said in a statement: 'Jill Sobule was a force of nature and human rights advocate whose music is woven into our culture. Extremely sad to hear of the passing of my old friend @jillsobule . A true original. She and I wrote 'Manchild', the closing song on the first EELS album in the South of France one night when EELS wasn't even a thing yet. So long, old friend. You were so much fun to be around. E — EELS (@THE_EELS) May 2, 2025 'I was having so much fun working with her. I lost a client and a friend today. I hope her music, memory, and legacy continue to live on and inspire others.' During her more than three decades of recording, Sobule released 12 albums that addressed such complex topics as the death penalty, anorexia nervosa, reproduction and LGBTQ+ issues. Her first album, Things Here Are Different, was released in 1990. Five years later, she received widespread attention for her hit singles, Supermodel, from the movie Clueless, and I Kissed A Girl, which, despite being banned on several southern radio stations, made it into the Billboard Top 20 in the US. Advertisement Oh, boy. Our dear friend @jillsobule has died. I'm really to numb to post much of anything. We loved her. She loved us. She was wonderful, brilliant, hilarious. We miss her, so much. — Lloyd Cole (@Lloyd_Cole) May 2, 2025 I Kissed A Girl has the same title as Katy Perry's 2008 worldwide hit, but they are two different songs. She also starred in an autobiographical off-Broadway musical that initially premiered at the Wild Project in New York in 2022 and includes songs and stories about her life. Sobule was known for taking control of her career by fundraising so she could make her next album. In 2008, after two major record companies dumped her and two indie labels went bankrupt beneath her, she raised tens of thousands of dollars from fans so she could make a new album. 'The old kind of paradigm, where you've always waited for other people to do things, you'd have your manager and your agent,' she said at the time. Advertisement 'You'd wait for the big record company to give you money to do things and they tell you what to do. This is so great. I want to do everything like this.' Sobule was scheduled to perform in Denver on Friday night. Instead, there will be an informal gathering hosted by her friend Ron Bostwick from 105.5 The Colorado Sound at the performance space where attendees can 'share a story or song', according to her publicist. Sobule achieved fame in the 1990s thanks to her work on the movie Clueless (AP) A formal memorial to celebrate her life and legacy will be held later this summer. Craig Grossman, her booking agent, said: 'No-one made me laugh more. Her spirit and energy shall be greatly missed within the music community and beyond.' Advertisement Born in Denver, Colorado, on January 16 1959, she has described herself as a shy child who preferred observing over participating. Sobule was known for playing dozens of shows a year and has described her live performances as vulnerable experiences. She said she often does not have a set list and wings it. She has performed with such icons as Neil Young, Billy Bragg and Cyndi Lauper, and also inducted Neil Diamond into the Songwriter's Hall of Fame, according to her website. She also sang a song as herself on an episode of The Simpsons in 2019. 'In a good way, I feel like I'm still a rookie,' she told The Associated Press in 2023 in an interview about her musical. 'There's so much more to do and I haven't done my best yet.' Advertisement She is survived by her brother and sister-in-law, James and Mary Ellen Sobule, along with her nephews and cousins.
Irish Examiner
02-05-2025
- Entertainment
- Irish Examiner
I Kissed A Girl singer-songwriter Jill Sobule dies in house fire
Jill Sobule, the award-winning singer-songwriter behind I Kissed A Girl, has died in a house fire aged 66. Her death in Woodbury, Minnesota, was confirmed by her publicist, David Elkin. It was not immediately clear how the fire started. John Porter, her manager, said in a statement: 'Jill Sobule was a force of nature and human rights advocate whose music is woven into our culture. Extremely sad to hear of the passing of my old friend @jillsobule. A true original. She and I wrote 'Manchild', the closing song on the first EELS album in the South of France one night when EELS wasn't even a thing yet. So long, old friend. You were so much fun to be around. E — EELS (@THE_EELS) May 2, 2025 'I was having so much fun working with her. I lost a client and a friend today. I hope her music, memory, and legacy continue to live on and inspire others.' During her more than three decades of recording, Sobule released 12 albums that addressed such complex topics as the death penalty, anorexia nervosa, reproduction and LGBTQ+ issues. Her first album, Things Here Are Different, was released in 1990. Five years later, she received widespread attention for her hit singles, Supermodel, from the movie Clueless, and I Kissed A Girl, which, despite being banned on several southern radio stations, made it into the Billboard Top 20 in the US. Oh, boy. Our dear friend @jillsobule has died. I'm really to numb to post much of anything. We loved her. She loved us. She was wonderful, brilliant, hilarious. We miss her, so much. — Lloyd Cole (@Lloyd_Cole) May 2, 2025 I Kissed A Girl has the same title as Katy Perry's 2008 worldwide hit, but they are two different songs. She also starred in an autobiographical off-Broadway musical that initially premiered at the Wild Project in New York in 2022 and includes songs and stories about her life. Sobule was known for taking control of her career by fundraising so she could make her next album. In 2008, after two major record companies dumped her and two indie labels went bankrupt beneath her, she raised tens of thousands of dollars from fans so she could make a new album. 'The old kind of paradigm, where you've always waited for other people to do things, you'd have your manager and your agent,' she said at the time. 'You'd wait for the big record company to give you money to do things and they tell you what to do. This is so great. I want to do everything like this.' Sobule was scheduled to perform in Denver on Friday night. Instead, there will be an informal gathering hosted by her friend Ron Bostwick from 105.5 The Colorado Sound at the performance space where attendees can 'share a story or song', according to her publicist. Sobule achieved fame in the 1990s thanks to her work on the movie Clueless (AP) A formal memorial to celebrate her life and legacy will be held later this summer. Craig Grossman, her booking agent, said: 'No-one made me laugh more. Her spirit and energy shall be greatly missed within the music community and beyond.' Born in Denver, Colorado, on January 16 1959, she has described herself as a shy child who preferred observing over participating. Sobule was known for playing dozens of shows a year and has described her live performances as vulnerable experiences. She said she often does not have a set list and wings it. She has performed with such icons as Neil Young, Billy Bragg and Cyndi Lauper, and also inducted Neil Diamond into the Songwriter's Hall of Fame, according to her website. She also sang a song as herself on an episode of The Simpsons in 2019. 'In a good way, I feel like I'm still a rookie,' she told The Associated Press in 2023 in an interview about her musical. 'There's so much more to do and I haven't done my best yet.' She is survived by her brother and sister-in-law, James and Mary Ellen Sobule, along with her nephews and cousins.
