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Globe and Mail
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- Business
- Globe and Mail
Wet Age-Related Macular Degeneration (Wet-AMD) Drugs Market 2034: Clinical Trials, EMA, PDMA, FDA Approvals, Medication, Therapies, Statistics, Revenue, Prevalence, and Companies by DelveInsight
Wet Age-Related Macular Degeneration Companies are Boehringer Ingelheim, Tyrogenex, Regenxbio, Ribomic, Outlook Therapeutics, Gemini Therapeutics, AiViva BioPharma, Opthea Limited, Iconic Therapeutics, Huabo Biopharm, Alkahest, IVERIC bio (formerly Ophthotech Corporation), Curacle, Dobecure, RemeGen, Isarna Therapeutics, Bio-Thera Solutions, Kodiak Sciences, AngioLab Inc, and others. (Albany, USA) DelveInsight's ' Wet Age-Related Macular Degeneration Market Insights, Epidemiology, and Market Forecast-2034 ' report delivers an in-depth understanding of the Wet Age-Related Macular Degeneration, historical and forecasted epidemiology as well as the Wet Age-Related Macular Degeneration market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. The Wet Age-Related Macular Degeneration market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Wet Age-Related Macular Degeneration market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Wet Age-Related Macular Degeneration treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Wet Age-Related Macular Degeneration market. Key Takeaways from the Wet Age-Related Macular Degeneration Market Report In May 2025, Kodiak Sciences Inc announced results of a Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Three-arm Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tarcocimab Tedromer and Tabirafusp Tedromer Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) In May 2025, NexThera Co., Ltd announced results of a Randomized, Open-Label, Parallel-group, Multicenter Phase 1/2 Study to Evaluate the Safety and Exploratory Efficacy of NT-101 Topical Ophthalmic Solution in Patients With Wet Age-Related Macular Degeneration (AMD) In April 2025, Kodiak Sciences Inc. announced phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tarcocimab Tedromer and Tabirafusp Tedromer Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD) In the assessment done by DelveInsight, the estimated total diagnosed prevalent cases of Age-Related Macular Degeneration (AMD) in the 7MM were nearly 40 million in 2023. The highest total diagnosed prevalent cases of Age-Related Macular Degeneration (AMD) were accounted by the US in 2023 (~14 million), which are expected to show a rise in the future. Among the European countries, Germany had the highest diagnosed prevalent cases of Age-Related Macular Degeneration (AMD) with ~6 million cases in 2023. On the other hand, Spain had the lowest prevalent population (~2 million cases). Japan had nearly 8 million total diagnosed prevalent cases of Age-Related Macular Degeneration (AMD) in 2023, accounting for approximately 21% in 7MM. Based on age-specific segmentation, the people in the age group of 70-79 were affected the most by Wet Age-Related Macular Degeneration (Wet AMD) in the US, accounting for approximately 406 thousand cases in 2023. The DelveInsight analysis indicates that in Japan, there are more number of cases of people with Dry AMD than people with Wet AMD, with approximately 90% of total cases and 10% of cases in 2023. Among the European countries, Germany had the highest diagnosed prevalent cases of Wet AMD with ~595 thousand cases, followed by France, which had prevalent population of ~389 thousand in 2023. On the other hand, Spain had the lowest prevalent population (~160 thousand cases). Japan had ~840 thousand total diagnosed prevalent cases of Wet Age-Related Macular Degeneration (Wet AMD) in 2023, accounting for approximately 21% in 7MM. In 2023, in the US, the age-specific diagnosed prevalent cases of Wet AMD were highest for age group 70-79 (~407 thousand), followed by 60-69 (~393 thousand), =80 (~304 thousand), and 50-59 (~252 thousand). The increase in Wet Age-Related Macular Degeneration Market Size is a direct consequence of the increasing patient population and anticipated launch of emerging therapies in the 7MM. As per DelveInsight analysis, the Wet Age-Related Macular Degeneration Market is anticipated to witness growth at a considerable CAGR. The leading Wet Age-Related Macular Degeneration Companies such as Boehringer Ingelheim, Tyrogenex, Regenxbio, Ribomic, Outlook Therapeutics, Gemini Therapeutics, AiViva BioPharma, Opthea Limited, Iconic Therapeutics, Huabo Biopharm, Alkahest, IVERIC bio (formerly Ophthotech Corporation), Curacle, Dobecure, RemeGen, Isarna Therapeutics, Bio-Thera Solutions, Kodiak Sciences, AngioLab Inc, and others. Promising Wet Age-Related Macular Degeneration Pipeline Therapies such as RGX-314, Tarcocimab tedromer, Aflibercept, KSI-301, Eyp-1901, ALK4290, and others. Wet Age-Related Macular Degeneration Epidemiology Segmentation in the 7MM The epidemiology section of Wet Age-Related Macular Degeneration offers insights into both historical and current patient populations, as well as forecasted trends across seven major countries. This section aids in understanding the factors behind present and projected trends through analysis of various studies and input from key opinion leaders. Additionally, this portion of the market report provides information on the diagnosed patient pool, trends, and underlying assumptions. Download the report to understand which factors are driving Wet Age-Related Macular Degeneration Epidemiology trends @ Wet Age-Related Macular Degeneration Marketed Drugs • BEOVU (Brolucizumab): Novartis BEOVU (Brolucizumab), developed by Novartis, is a potent anti-VEGF treatment used for Wet Age-Related Macular Degeneration (Wet-AMD). It works by inhibiting vascular endothelial growth factor, reducing abnormal blood vessel growth and fluid leakage in the retina. BEOVU offers a longer dosing interval, allowing up to 12-week dosing schedules. • EYLEA (aflibercept): Regeneron Pharmaceuticals EYLEA, developed by Regeneron, is used to treat wet age-related macular degeneration (wet-AMD), diabetic eye disease, and other retinal issues. The drug, aflibercept, is an injectable treatment that slows vision loss by blocking abnormal blood vessel growth in the eye. EYLEA works as a soluble decoy receptor, inhibiting VEGF-A and PlGF to prevent abnormal blood vessel formation. The standard dosage is 2 mg every 4 weeks for the first 3 months, then every 8 weeks. Regeneron is currently testing less frequent dosing and higher doses in ongoing phase III trials. • VABYSMO (faricimab): Roche/ Genentech, Inc. VABYSMO (faricimab) is the first bispecific antibody designed for the eye. It targets and inhibits two signalling pathways linked to a number of vision-threatening retinal conditions by neutralizing angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Ang-2 and VEGF-A contribute to vision loss by destabilizing blood vessels, causing new leaky blood vessels to form and increasing inflammation. By blocking both pathways involving Ang-2 and VEGF-A, VABYSMO is designed to stabilize blood vessels. Wet Age-Related Macular Degeneration Emerging Drugs • OPT-302: Opthea Limited OPT-302 (sVEGFR-3) is the first 'Trap' inhibitor of VEGF-C and VEGF-D designed specifically for the eye. OPT-302 blocks the two members of the VEGF family which cause blood vessels to grow and leak. Aberrant blood vessel growth and vascular leakage are hallmarks of several eye diseases, including wet AMD and DME. In combination with anti-VEGF-A therapies, OPT-302 completely shuts-down VEGFR-2 and VEGFR-3 activity and targets mechanisms of resistance and suboptimal clinical response to existing therapies. • KSI-501: Kodiak Sciences Inc. KSI-501 is a novel anti-VEGF biologic designed to rapidly inhibit VEGF and provide extended durability of action to reduce the burden of frequent anti-VEGF injections. Delivering potent and sustained VEGF inhibition enables patient compliance, results in long-term efficacy, and improves visual acuity outcomes. Wet Age-Related Macular Degeneration Market Outlook Wet Age-Related Macular Degeneration (wet AMD) is a progressive eye condition characterized by the growth of abnormal blood vessels beneath the retina, which can lead to severe vision loss. Treatment aims to manage symptoms, slow disease progression, and preserve vision. The primary therapeutic approach for wet AMD is anti-vascular endothelial growth factor (anti-VEGF) therapy. These medications, including ranibizumab (LUCENTIS), aflibercept (EYLEA), and brolucizumab (BEOVU), work by inhibiting VEGF, a protein that promotes the growth of abnormal blood vessels. Administered via intravitreal injections, these drugs reduce fluid leakage and vascular growth, stabilizing or improving vision in many patients. The Wet Age-Related Macular Degeneration (wAMD) market is driven by several key factors, including the rising prevalence of the disease due to an aging global population, increased awareness and early diagnosis, and ongoing advancements in treatment options such as anti-VEGF therapies and emerging gene therapies. Additionally, robust research pipelines, growing healthcare expenditure, and supportive government initiatives further contribute to market growth. However, the market also faces notable barriers, such as the high cost of treatment, limited accessibility in low-income regions, the need for frequent intravitreal injections, and challenges in achieving long-term efficacy and patient adherence. Moreover, competition among therapeutic alternatives and the complex nature of drug development for retinal diseases can also hinder market expansion. Wet Age-Related Macular Degeneration Drugs Uptake The drug chapter of the Wet Age-Related Macular Degeneration report provides a comprehensive analysis of both marketed drugs and late-stage pipeline drugs for this condition. It delves into the details of clinical trials, pharmacological actions, agreements, collaborations, approvals, patents, and advantages, and disadvantages of each drug, as well as the latest news and press releases related to Wet Age-Related Macular Degeneration. Major Wet Age-Related Macular Degeneration Companies are Opthea Limited (ASX: OPT), Outlook Therapeutics (NASDAQ: OTLK), Kodiak Sciences (NASDAQ: KOD), Regenxbio (NASDAQ: RGNX), Dobecure (Private), Gemini Therapeutics (NASDAQ: GMTX), Huabo Biopharm (Private), Isarna Therapeutics (Private), IVERIC bio (NASDAQ: ISEE), Ribomic (TYO: 4591), Curacle (KOSDAQ: 301300), Bio-Thera Solutions (SHA: 688177), AngioLab Inc. (KOSDAQ: 251280), Alkahest (Acquired by Grifols – BME: GRF), Tyrogenex (Private), Iconic Therapeutics (Private), AiViva BioPharma (Private), Boehringer Ingelheim (Private), RemeGen (HKEX: 9995, SHA: 688331), and others Scope of the Wet Age-Related Macular Degeneration Market Report Coverage- 7MM Study Period- 2020-2034 Wet Age-Related Macular Degeneration Companies- Boehringer Ingelheim, Tyrogenex, Regenxbio, Ribomic, Outlook Therapeutics, Gemini Therapeutics, AiViva BioPharma, Opthea Limited, Iconic Therapeutics, Huabo Biopharm, Alkahest, IVERIC bio (formerly Ophthotech Corporation), Curacle, Dobecure, RemeGen, Isarna Therapeutics, Bio-Thera Solutions, Kodiak Sciences, AngioLab Inc, and others. Wet Age-Related Macular Degeneration Pipeline Therapies- RGX-314, Tarcocimab tedromer, Aflibercept, KSI-301, Eyp-1901, ALK4290, and others. Wet Age-Related Macular Degeneration Market Dynamics: Wet Age-Related Macular Degeneration Market Drivers and Barriers Wet Age-Related Macular Degeneration Market Access and Reimbursement, Unmet Needs and Future Perspectives Discover more about Wet Age-Related Macular Degeneration Drugs in development @ Wet Age-Related Macular Degeneration Clinical Trials Assessment and FDA Approvals Table of Content 1 Key Insights 2 Report Introduction 3 Wet AMD Market Overview at a Glance 4 Wet AMD Market: Future Perspective 5 Executive Summary 6 Key Events 7 Disease Background and Overview 8 Epidemiology and Patient Population 9 Patient Journey 10 Marketed Drugs 11 Emerging Drugs of Wet AMD 12 Wet AMD: Market Analysis 13 Key Opinion Leaders' Views 14 SWOT Analysis 15 Unmet Needs 16 Market Access and Reimbursement 17 Appendix 18 DelveInsight Capabilities 19 Disclaimer About DelveInsight DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Ankit Nigam Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Albany State: New York Country: United States Website:
Globe and Mail
26-05-2025
- Health
- Globe and Mail
Unstable Angina Market on Track for Major Expansion by 2032, According to DelveInsight
The Key Unstable Angina Companies in the market include - Tasly Pharmaceuticals, Arbor Pharmaceuticals, and others. The Unstable Angina market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Unstable Angina pipeline products will significantly revolutionize the Unstable Angina market dynamics. DelveInsight's 'Unstable Angina Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the Unstable Angina, historical and forecasted epidemiology as well as the Unstable Angina market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan. The Unstable Angina market report covers emerging drugs, current treatment practices, market share of the individual therapies, and current & forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best of the opportunities and assess the underlying potential of the market. Some of the key facts of the Unstable Angina Market Report: The Unstable Angina market size is anticipated to grow with a significant CAGR during the study period (2019-2032) In November 2024, Saghmos is developing ST-62516 (trimetazidine), a cardiorenal metabolic modulator aimed at lowering the risk of Acute Kidney Injury (AKI) and Major Adverse Cardiac and Kidney Events (MACKE) following contrast-based procedures like percutaneous coronary intervention (PCI). In the US, over one million PCI procedures are performed annually on patients with unstable angina, with around half having additional health conditions that affect PCI safety. This represents a significant unmet medical need, as no FDA-approved treatments currently exist to prevent or manage AKI and MACKE. Saghmos Therapeutics is partnering with the Duke Clinical Research Institute to refine and execute the Phase 3 trial for ST-62516. Coronary heart disease (CHD) impacts over 17 million adults in the United States. Of the 17 million Americans affected, 55% of those are male. Angina affects 10 million people in the United States According to the study of Nathan Messas, Unstable Angina or Angina pectoris is the most prevalent manifestation of myocardial ischemia and coronary artery disease (CAD), affecting up to 9 million patients in the United States Key Unstable Angina Companies: Tasly Pharmaceuticals, Arbor Pharmaceuticals, and others Key Unstable Angina Therapies: T89, AR36, and others The Unstable Angina epidemiology based on gender analyzed that it can be concluded that Unstable Angina is more common in males than female Unstable Angina Overview Unstable angina is a type of chest pain that occurs suddenly and unpredictably due to reduced blood flow to the heart. It is a medical emergency and a warning sign of an impending heart attack. Unlike stable angina, it can occur at rest, lasts longer, and may not be relieved by medication or rest. It results from the rupture of a plaque in the coronary artery, leading to partial blockage. Immediate treatment is essential to restore blood flow and prevent heart damage. Unstable Angina Market The dynamics of the Unstable Angina market are anticipated to change in the coming years owing to the expected launch of emerging therapies and others during the forecasted period 2019-2032. 'The emerging pipeline for the treatment of Unstable Angina have few candidates. These products are in mid or last stage of investigation. With the launch of emerging therapies the total market of Unstable Angina is supposed to experience immense changes in the future' Unstable Angina Epidemiology The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends. Unstable Angina Epidemiology Segmentation: The Unstable Angina market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into: Unstable Angina Drugs Uptake and Pipeline Development Activities The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Unstable Angina market or expected to get launched during the study period. The analysis covers Unstable Angina market uptake by drugs, patient uptake by therapies, and sales of each drug. Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share. The report also covers the Unstable Angina Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies. Unstable Angina Therapies and Key Companies Scope of the Unstable Angina Market Report Table of Contents 1. Unstable Angina Market Report Introduction 2. Executive Summary for Unstable Angina 3. SWOT analysis of Unstable Angina 4. Unstable Angina Patient Share (%) Overview at a Glance 5. Unstable Angina Market Overview at a Glance 6. Unstable Angina Disease Background and Overview 7. Unstable Angina Epidemiology and Patient Population 8. Country-Specific Patient Population of Unstable Angina 9. Unstable Angina Current Treatment and Medical Practices 10. Unstable Angina Unmet Needs 11. Unstable Angina Emerging Therapies 12. Unstable Angina Market Outlook 13. Country-Wise Unstable Angina Market Analysis (2019–2032) 14. Unstable Angina Market Access and Reimbursement of Therapies 15. Unstable Angina Market Drivers 16. Unstable Angina Market Barriers 17. Unstable Angina Appendix 18. Unstable Angina Report Methodology 19. DelveInsight Capabilities 20. Disclaimer 21. About DelveInsight About DelveInsight DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Gaurav Bora Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: NV Country: United States Website:
Globe and Mail
23-05-2025
- Business
- Globe and Mail
Actinic Keratosis Drugs Market 2034: Clinical Trials, EMA, PDMA, FDA Approvals, Prevalence, Medication, Therapies, NICE Approvals and Companies by DelveInsight
Actinic Keratosis companies are VidacPharma, DFB Soria, G&E Herbal Biotechnology, Promius Pharma, Sol-Gel Technologies, PROVECTUS BIOPHARMACEUTICALS, Coegin Pharma, Jupiter Wellness, MedC Biopharma CorporationGlaukos Corporation, Ivantis Inc., Allergan, Ellex, Alcon, BVI, Johnson and Johnson Services, Inc., Microsurgical technology, Molteno Ophthalmic Ltd. ,New World Medical , Santen Pharmaceutical, Sight Scientific, Topcon Corporation, Merck & Co., Inc., Carl Zeiss AG, among others. (Albany, USA) DelveInsight's " Actinic Keratosis Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of Actinic Keratosis, historical and forecasted epidemiology as well as the Actinic Keratosis market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan. The Actinic Keratosis market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Actinic Keratosis market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Actinic Keratosis treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Actinic Keratosis market. Some facts of the Actinic Keratosis Market Report are: According to DelveInsight, Actinic Keratosis market size is expected to grow at a decent CAGR by 2034. Leading Actinic Keratosis companies working in the market are VidacPharma, DFB Soria, G&E Herbal Biotechnology, Promius Pharma, Sol-Gel Technologies, PROVECTUS BIOPHARMACEUTICALS, Coegin Pharma, Jupiter Wellness, MedC Biopharma CorporationGlaukos Corporation, Ivantis Inc., Allergan, Ellex, Alcon, BVI, Johnson and Johnson Services, Inc., Microsurgical technology, Molteno Ophthalmic Ltd. ,New World Medical , Santen Pharmaceutical, Sight Scientific, Topcon Corporation, Merck & Co., Inc., Carl Zeiss AG, Alimera Sciences, Annexin Pharmaceuticals, Amgen Inc., Cangene Corporation, BD and Bosch Healthcare Solutions GmbH among others. Key Actinic Keratosis Therapies expected to launch in the market are AVX001, VDA-1102, and others. In February 2025, Almirall, S.A announced results of a Phase 3, Multicentre, Randomised, Double-blind, Vehicle-controlled, Parallel-group Study to Evaluate the Efficacy and Safety of Tirbanibulin 10 mg/g Ointment Applied to a Treatment Field Larger Than 25 cm^2 and up to 100 cm^2 in Adult Patients With Actinic Keratosis In November 2024, Vidac Pharma has secured €600,000 ($645,651) in additional funding to advance the clinical development of its two lead cancer candidates. Announced during the company's recent shareholder meeting, this funding from existing investors will allow Vidac to initiate a new Phase IIb trial for its lead candidate, VDA-1102 (tuvatexib) ointment. The hexokinase 2 inhibitor is being studied for its potential in treating advanced cases of actinic keratosis, a skin condition that may progress to cutaneous squamous cell carcinoma (SCC). In May 2024, TORQUR announced results of a Randomized Phase 2 Proof-of-Concept Study to Evaluate the Efficacy and Safety of Topical Bimiralisib Application in Participants Suffering From Actinic Keratosis on the Face and/or Scalp and/or Back of Hands Over a 2 and 4-week Treatment Period Additionally, the launch of new therapies such as VDA-1102, SR-T100 Gel, and other innovative topical treatments is anticipated to enhance treatment outcomes and broaden market prospects. According to Chetty P et al., the prevalence of AK varies from 6–60%, depending on age, phototype and other predisposing risk factors (most notably immunosuppressed status, outdoor workers), and is increasing In a study conducted by Schaefer et al., it was found that the standardized prevalence of AK from dermatological examinations was 2.7%; the rate increased with age (11.5% in the group 60-70 years) and was higher for men (3.9%) than for women (1.5%) Actinic Keratosis Overview Actinic keratosis (AK) is a common skin condition characterized by rough, scaly patches that develop due to long-term exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Actinic keratosis usually occurs on areas of the body that receive the most sun exposure, such as the face, scalp, ears, neck, and hands. These lesions are usually small, red, or flesh-colored, with a rough texture resembling sandpaper. While actinic keratosis is not cancerous in itself, it is considered a precancerous condition, as a small percentage of Actinic keratosis may progress to squamous cell carcinoma, a type of skin cancer. It is important to have Actinic keratosis evaluated and treated by a healthcare professional. Treatment options include topical creams, cryotherapy (freezing), chemical peels, photodynamic therapy, or surgical removal. Prevention is crucial, and measures such as sun protection (using sunscreen, wearing protective clothing, and seeking shade), regular skin examinations, and avoiding artificial UV radiation can help reduce the risk of developing actinic keratosis. Early detection and treatment of Actinic keratosis can significantly lower the risk of skin cancer. Actinic Keratosis Market The Actinic Keratosis market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Actinic Keratosis market trends by analyzing the impact of current Actinic Keratosis therapies on the market and unmet needs, and drivers, barriers, and demand for better technology. This segment gives a thorough detail of the Actinic Keratosis market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Actinic Keratosis market data are presented with relevant tables and graphs to give a clear view of the market at first sight. According to DelveInsight, the Actinic Keratosis market in 7MM is expected to witness a major change in the study period 2020-2034. Actinic Keratosis Epidemiology The Actinic Keratosis epidemiology section provides insights into the historical and current Actinic Keratosis patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Actinic Keratosis market report also provides the diagnosed patient pool, trends, and assumptions. Actinic Keratosis Drugs Uptake This section focuses on the uptake rate of the potential Actinic Keratosis drugs recently launched in the Actinic Keratosis market or expected to be launched in 2020-2034. The analysis covers the Actinic Keratosis market uptake by drugs, patient uptake by therapies, and sales of each drug. Actinic Keratosis Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Actinic Keratosis market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions. Actinic Keratosis Pipeline Development Activities The Actinic Keratosis report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Actinic Keratosis key players involved in developing targeted therapeutics. Learn more about the emerging Actinic Keratosis Market drivers and barriers @ Actinic Keratosis Market Dynamics Actinic Keratosis Therapeutics Assessment Major key companies are working proactively in the Actinic Keratosis Therapeutics market to develop novel therapies which will drive the Actinic Keratosis treatment markets in the upcoming years are VidacPharma, DFB Soria, G&E Herbal Biotechnology, Promius Pharma, Sol-Gel Technologies, PROVECTUS BIOPHARMACEUTICALS, Coegin Pharma, Jupiter Wellness, MedC Biopharma CorporationGlaukos Corporation, Ivantis Inc., Allergan, Ellex, Alcon, BVI, Johnson and Johnson Services, Inc., Microsurgical technology, Molteno Ophthalmic Ltd. ,New World Medical , Santen Pharmaceutical, Sight Scientific, Topcon Corporation, Merck & Co., Inc., Carl Zeiss AG, Alimera Sciences, Annexin Pharmaceuticals, Amgen Inc., Cangene Corporation, BD and Bosch Healthcare Solutions GmbH among others. Actinic Keratosis Therapies and Companies Actinic Keratosis Report Key Insights 1. Actinic Keratosis Patient Population 2. Actinic Keratosis Market Size and Trends 3. Key Cross Competition in the Actinic Keratosis Market 4. Actinic Keratosis Market Dynamics (Key Drivers and Barriers) 5. Actinic Keratosis Market Opportunities 6. Actinic Keratosis Therapeutic Approaches 7. Actinic Keratosis Pipeline Analysis 8. Actinic Keratosis Current Treatment Practices/Algorithm 9. Impact of Emerging Therapies on the Actinic Keratosis Market Table of Contents 1. Key Insights 2. Executive Summary 3. Actinic Keratosis Competitive Intelligence Analysis 4. Actinic Keratosis Market Overview at a Glance 5. Actinic Keratosis Disease Background and Overview 6. Actinic Keratosis Patient Journey 7. Actinic Keratosis Epidemiology and Patient Population 8. Actinic Keratosis Treatment Algorithm, Current Treatment, and Medical Practices 9. Actinic Keratosis Unmet Needs 10. Key Endpoints of Actinic Keratosis Treatment 11. Actinic Keratosis Marketed Products 12. Actinic Keratosis Emerging Therapies 13. Actinic Keratosis Seven Major Market Analysis 14. Attribute Analysis 15. Actinic Keratosis Market Outlook (7 major markets) 16. Actinic Keratosis Access and Reimbursement Overview 17. KOL Views on the Actinic Keratosis Market 18. Actinic Keratosis Market Drivers 19. Actinic Keratosis Market Barriers 20. Appendix 21. DelveInsight Capabilities 22. Disclaimer About DelveInsight DelveInsight is a leading Life Science market research and business consulting company recognized for its off-the-shelf syndicated market research reports and customized solutions to firms in the healthcare sector. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Ankit Nigam Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Albany State: New York Country: United States Website:
Globe and Mail
16-05-2025
- Health
- Globe and Mail
Coagulation Factor Deficiency Market to Witness Significant Innovation and Growth by 2034
The Coagulation Factor Deficiency market is evolving rapidly, fueled by advances in gene therapy, long-acting clotting factors, and better prophylaxis. DelveInsight's report covers epidemiology and treatments for Hemophilia A, B, and rare factor deficiencies (FVII, FXI, FXIII). AAV-based gene therapies are driving new treatment goals and improving outcomes, especially for underserved patients. DelveInsight's ' Coagulation Factor Deficiency Market Report ' delivers detailed analysis of market dynamics, historical and forecasted epidemiology, and emerging therapies across the 7MM (US, EU5, and Japan), highlighting key players and trends driving this rare disease segment. Some of the Key Facts of the Coagulation Factor Deficiency Market Report: • In 2023, the coagulation factor deficiency market in the 7MM was valued at approximately USD 13.5 billion. • The US led the market, contributing around USD 7.2 billion. • There were about 105K prevalent cases across the 7MM, with the US accounting for nearly 34K. • Hemophilia A was the most common subtype among all coagulation factor deficiencies. • Marketed drugs for coagulation factor deficiency include ESPEROCT (Novo Nordisk), JIVI (Bayer), and WILATE (Octapharma). • In March 2025, the FDA approved QFITLIA (fitusiran) for routine prophylaxis to reduce bleeding episodes in patients (12+) with hemophilia A or B, with or without factor VIII or IX inhibitors. • In December 2024, Novo announced that the FDA approved concizumab, its tissue factor pathway inhibitor (TFPI) antagonist, as a once-daily treatment to prevent or reduce bleeding episodes in patients aged 12 and older with hemophilia A or B with inhibitors. • In October 2024, Novo Nordisk received support from European regulators for the approval of its anti-TFPI antibody, Alhemo (concizumab), as a preventive treatment for hemophilia. The company stated that, if approved, this therapy would provide the first subcutaneous prophylactic treatment to be administered once daily for individuals with hemophilia A or B who have inhibitors. • In March 2024, ReciBioPharm signed a collaboration agreement with GeneVentiv Therapeutics, a preclinical gene therapy company, to advance the development of an adeno-associated virus (AAV)-based universal gene therapy for hemophilia, and reportedly the first to treat hemophilia patients with inhibitors. • Emerging coagulation factor deficiency drugs include Concizumab, Fidanacogene Elaparvovec, RG6357 (SPK-8011), Fitusiran, Marstacimab, Giroctocogene Fitelparvovec, NNC0365-3769 A (MIM8), BT524, SerpinPC, STSP-0601, Marzeptacog Alfa, AB023, BAY2599023, OPK88005, and others. • Leading companies in the coagulation factor deficiency market include Novo Nordisk, Pfizer, Spark Therapeutics, Roche, Sanofi (Genzyme), Alnylam Pharmaceuticals, Sangamo Therapeutics, Biotest AG, Centessa Pharmaceuticals (ApcinteX), Staidson Biopharma Inc., GC Biopharma, Aronora, Inc., Bayer, Ultragenyx Pharmaceutical, OPKO Health, Inc., and others. • The rising incidence of coagulation factor deficiencies, along with ongoing advancements in treatment options, is driving the demand for more effective therapies for these conditions. To know in detail about the coagulation factor deficiency market outlook, drug uptake, treatment scenario, and epidemiology trends, click here: Coagulation Factor Deficiency Market Forecast Coagulation Factor Deficiency Overview Coagulation factor deficiencies, also referred to as bleeding or clotting disorders, are a group of inherited or acquired conditions caused by the absence or dysfunction of specific proteins that are essential for blood clotting. These proteins, known as coagulation factors, are vital for halting bleeding by forming clots to close off damaged blood vessels. There are 13 coagulation factors, each numbered from I to XIII, that work together in a complex process to maintain hemostasis. Deficiencies in any of these factors can lead to abnormal bleeding, with severity varying based on the specific factor affected and the extent of the deficiency. Get a free sample of the coagulation factor deficiency market report with key insights and emerging therapies here: Coagulation Factor Deficiency Epidemiology The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends. Coagulation Factor Deficiency Epidemiology Segmentation: The coagulation factor deficiency epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by: • Total diagnosed prevalent cases • Factor-specific prevalent cases Download the report to understand which factors are driving coagulation factor deficiency epidemiology trends @ Coagulation Factor Deficiency Epidemiology Forecast Coagulation Factor Deficiency Drugs Uptake, and Pipeline Development Activities The coagulation factor deficiency drugs uptake section examines the rate at which newly launched or upcoming potential drugs are being adopted in the coagulation factor deficiency market during the study period. This analysis covers drug uptake, patient adoption of therapies, and the sales performance of each drug. Additionally, the therapeutics assessment section highlights the drugs with the most rapid uptake, shedding light on the factors driving their widespread use. It also provides a comparative analysis of these drugs based on their market share. The report further delves into the coagulation factor deficiency pipeline development activities, offering key insights into various therapeutic candidates in different stages of development and the major companies behind these innovations. It also covers recent collaborations, acquisitions, mergers, licensing agreements, patent details, and other critical information related to emerging therapies. Coagulation Factor Deficiency Market Strengths • New gene therapies for coagulation factor deficiencies, like Hemophilia A and B, offer potential long-term or curative solutions. • Better awareness and diagnostic tools are enabling earlier detection and more effective management. Coagulation Factor Deficiency Market Weaknesses •Many therapies, particularly gene therapies, remain expensive, limiting accessibility. • Advanced therapies are not widely accessible in lower-income regions due to cost and healthcare limitations. Scope of the Coagulation Factor Deficiency Market Report • Study Period: 2020–2034 • Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan] • Key Coagulation Factor Deficiency Therapies: Concizumab, Fidanacogene Elaparvovec, RG6357 (SPK-8011), Fitusiran, Marstacimab, Giroctocogene Fitelparvovec, NNC0365-3769 A (MIM8), BT524, SerpinPC, STSP-0601, Marzeptacog Alfa, AB023, BAY2599023, OPK88005, and others. • Key Coagulation Factor Deficiency Companies: Novo Nordisk, Pfizer, Spark Therapeutics, Roche, Sanofi (Genzyme), Alnylam Pharmaceuticals, Sangamo Therapeutics, Biotest AG, Centessa Pharmaceuticals (ApcinteX), Staidson Biopharma Inc., GC Biopharma, Aronora, Inc., Bayer, Ultragenyx Pharmaceutical, OPKO Health, Inc., and others. • Coagulation Factor Deficiency Therapeutic Assessment: Coagulation factor deficiency, currently marketed, and coagulation factor deficiency emerging therapies • Coagulation Factor Deficiency Market Dynamics: Coagulation factor deficiency market drivers and Coagulation Factor Deficiency market barriers • Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies • Coagulation Factor Deficiency Unmet Needs, KOL's views, Analyst's views, Coagulation Factor Deficiency Market Access and Reimbursement To learn more about the key players and advancements in the coagulation factor deficiency treatment landscape, visit the Coagulation Factor Deficiency Market Analysis Report Table of Contents 1. Coagulation Factor Deficiency Market Report Introduction 2. Executive Summary for Coagulation Factor Deficiency 3. SWOT analysis of Coagulation Factor Deficiency 4. Coagulation Factor Deficiency Patient Share (%) Overview at a Glance 5. Coagulation Factor Deficiency Market Overview at a Glance 6. Coagulation Factor Deficiency Disease Background and Overview 7. Coagulation Factor Deficiency Epidemiology and Patient Population 8. Country-Specific Patient Population of Coagulation Factor Deficiency 9. Coagulation Factor Deficiency Current Treatment and Medical Practices 10. Coagulation Factor Deficiency Unmet Needs 11. Coagulation Factor Deficiency Emerging Therapies 12. Coagulation Factor Deficiency Market Outlook 13. Country-Wise Coagulation Factor Deficiency Market Analysis (2020–2034) 14. Coagulation Factor Deficiency Market Access and Reimbursement of Therapies 15. Coagulation Factor Deficiency Market Drivers 16. Coagulation Factor Deficiency Market Barriers 17. Coagulation Factor Deficiency Appendix 18. Coagulation Factor Deficiency Report Methodology 19. DelveInsight Capabilities 20. Disclaimer 21. About DelveInsight About DelveInsight DelveInsight is a leading Healthcare Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach. Media Contact Company Name: DelveInsight Contact Person: Jatin Vimal Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: Nevada Country: United States Website:
Globe and Mail
16-05-2025
- Health
- Globe and Mail
Anemia in Chronic Kidney Disease Market Set for Significant Growth and Innovation by 2034
Anemia in Chronic Kidney Disease (CKD), a common and debilitating complication resulting from reduced erythropoietin production and iron deficiency, continues to pose serious clinical challenges and an economic burden. DelveInsight's comprehensive report on the Anemia in CKD market sheds light on the evolving understanding and management of this condition, which affects a substantial proportion of patients with moderate to advanced CKD. With improved awareness and screening, earlier diagnosis and intervention are becoming more achievable, especially with the support of emerging biomarkers and treatment guidelines. Innovative therapies such as HIF-PH inhibitors and long-acting erythropoiesis-stimulating agents (ESAs) are shaping a dynamic treatment landscape aimed at improving hemoglobin levels with fewer side effects. DelveInsight's ' Anemia in Chronic Kidney Disease Market Report ' offers an in-depth analysis of the epidemiology, disease burden, and market outlook across key geographies, including the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan. The report highlights current unmet needs, late-stage pipeline therapies, market drivers and barriers, and the key players transforming patient care, making it a vital resource for healthcare stakeholders and innovators in nephrology. Some of the Key Facts of the Anemia in Chronic Kidney Disease Market Report: • The anemia in chronic kidney disease is expected to grow at a significant CAGR by 2034. • In 2023, the United States recorded the highest number of prevalent Anemia in Chronic Kidney Disease (CKD) cases among the 7MM. • The U.S. also accounted for the highest number of treated cases of Anemia in CKD during the same year. • A higher prevalence was noted among individuals aged 60 and above compared to those under 60 in the U.S. • Males with CKD had a 30% higher risk of developing anemia compared to females. • Among the EU4 and the UK, Spain reported the lowest number of anemia in CKD cases in 2023. • In Japan, anemia was one of the most frequently documented outcomes, with prevalence rates ranging from 0% to 95%, depending on CKD severity and dialysis status. • In March 2025, the FDA expanded the approval of Furoscix to include the treatment of edema in patients with chronic kidney disease, including nephrotic syndrome. • In March 2025, scPharmaceuticals received FDA approval for a supplemental new drug application (sNDA) for Furoscix (furosemide injection). This approval expands the drug's use to treat edema in patients with chronic kidney disease (CKD), marking a significant advancement in scPharmaceuticals' portfolio for cardiorenal conditions. • In March 2025, the FDA approved an expanded indication for furosemide injection (Furoscix; scPharmaceuticals, Inc.) to treat edema in adult patients with chronic kidney disease (CKD), including nephrotic syndrome. The expanded treatment is expected to be available by April 2025. This approval follows the FDA's acceptance of the supplemental new drug application in July 2024. • In January 2025, the FDA approved a new indication for semaglutide to reduce the risk of worsening kidney disease, kidney failure, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease, according to Novo Nordisk. • In November 2024, Unicycive Therapeutics (Nasdaq: UNCY) announced that the FDA has accepted its New Drug Application (NDA) for Oxylanthanum Carbonate (OLC), with a PDUFA target action date set for June 28, 2025. If approved, OLC has the potential to significantly enhance the treatment of hyperphosphatemia in chronic kidney disease (CKD) patients undergoing dialysis. • Leading companies in the anemia in chronic kidney disease market include Jiangsu HengRui Medicine, Shenyang Sunshine Pharmaceutical, Biocad, Xenetic Biosciences, Chiasma, Liminal BioSciences, Acceleron Pharma, Celgene Corporation, and others. • Emerging therapies in the anemia in chronic kidney disease market include DDO-3055, SSS17, BCD-131, BCD-066, Erythropoietin polysialic, CHIP 2, PBI 1402, Sotatercept, and others. • The rising prevalence of anemia in chronic kidney disease, along with continuous advancements in therapeutic options, is fueling the demand for more effective treatment approaches. To know in detail about the anemia in chronic kidney disease market outlook, drug uptake, treatment scenario, and epidemiology trends, click here: Anemia In Chronic Kidney Disease Market Forecast Anemia in Chronic Kidney Disease Overview Anemia is a frequent and serious complication of Chronic Kidney Disease (CKD), arising as kidney function declines and the body's ability to produce adequate erythropoietin—a hormone essential for red blood cell production, diminishes. CKD impairs the kidneys' filtering ability, leading to the accumulation of waste and fluids, which further contributes to the onset of anemia. The condition becomes increasingly prevalent in advanced stages of CKD. In the United States, over 37 million adults are estimated to have CKD, and more than one in seven individuals with CKD also suffer from anemia. The risk intensifies as kidney function deteriorates, with nearly all individuals at end-stage kidney failure (when kidney function drops below 15%) experiencing anemia. Certain populations are more susceptible: individuals with CKD and diabetes are at higher risk of developing anemia earlier and in more severe forms. Additionally, people over the age of 60 are more likely to be affected. The progression of CKD-related anemia is typically gradual and may remain asymptomatic in its early stages, making early detection and management crucial for improving patient outcomes. Get a free sample of the anemia in chronic kidney disease market report with key insights and emerging therapies here: Anemia in Chronic Kidney Disease Epidemiology The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2020 to 2034. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends. Anemia in Chronic Kidney Disease Epidemiology Segmentation: The anemia in chronic kidney disease epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by: • Total Prevalent Cases of Chronic Kidney Disease • Diagnosed Cases of Anemia in Chronic Kidney Disease • Age-Specific Prevalent Cases of Anemia in Chronic Kidney Disease • Total Prevalent Cases of Anemia in Chronic Kidney Disease • Total Prevalent Cases of Anemia in Different Stages of Chronic Kidney Disease • Treatable Cases of Anemia in Chronic Kidney Disease Download the report to understand which factors are driving anemia in chronic kidney disease epidemiology trends @ Anemia In Chronic Kidney Disease Epidemiology Forecast The anemia in chronic kidney disease drugs uptake section examines the rate at which newly launched or upcoming potential drugs are being adopted in the anemia in chronic kidney disease market during the study period. This analysis covers drug uptake, patient adoption of therapies, and the sales performance of each drug. Additionally, the therapeutics assessment section highlights the drugs with the most rapid uptake, shedding light on the factors driving their widespread use. It also provides a comparative analysis of these drugs based on their market share. The report further delves into the anemia in chronic kidney disease pipeline development activities, offering key insights into various therapeutic candidates in different stages of development and the major companies behind these innovations. It also covers recent collaborations, acquisitions, mergers, licensing agreements, patent details, and other critical information related to emerging therapies. Anemia in Chronic Kidney Disease Market Strengths • The availability of novel oral treatment options, such as daprodustat, offers more convenient and effective routes of administration for patients. • Active research and ongoing clinical trials are enhancing the understanding of the disease and driving innovation in therapeutic strategies. Anemia in Chronic Kidney Disease Market Weaknesses • Patients often struggle to recognize or differentiate the symptoms of anemia from CKD or other related conditions, leading to underreporting. • Healthcare providers, particularly in non-dialysis settings, frequently under-monitor hemoglobin levels and iron stores, resulting in delayed or suboptimal treatment initiation. Scope of the Anemia in Chronic Kidney Disease Market Report • Study Period: 2020–2034 • Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan] • Key Anemia In Chronic Kidney Disease Companies: GlaxoSmithKline, Teva Pharmaceuticals, Cipla, Sun Pharmaceuticals, and others. • Key Anemia In Chronic Kidney Disease Therapies: DDO-3055, SSS17, BCD-131, BCD-066, Erythropoietin polysialic, CHIP 2, PBI 1402, Sotatercept, and others. • Anemia In Chronic Kidney Disease Therapeutic Assessment: Anemia in chronic kidney disease, currently marketed, and anemia in chronic kidney disease emerging therapies • Anemia In Chronic Kidney Disease Market Dynamics: Anemia in chronic kidney disease market drivers and anemia in chronic kidney disease market barriers • Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies • Anemia In Chronic Kidney Disease Unmet Needs, KOL's views, Analyst's views, Anemia In Chronic Kidney Disease Market Access and Reimbursement To learn more about the key players and advancements in the anemia in chronic kidney disease treatment landscape, visit the Table of Contents 1. Anemia In Chronic Kidney Disease Market Report Introduction 2. Executive Summary for Anemia In Chronic Kidney Disease 3. SWOT analysis of Anemia In Chronic Kidney Disease 4. Anemia In Chronic Kidney Disease Patient Share (%) Overview at a Glance 5. Anemia In Chronic Kidney Disease Market Overview at a Glance 6. Anemia In Chronic Kidney Disease Disease Background and Overview 7. Anemia In Chronic Kidney Disease Epidemiology and Patient Population 8. Country-Specific Patient Population of Anemia In Chronic Kidney Disease 9. Anemia In Chronic Kidney Disease Current Treatment and Medical Practices 10. Anemia In Chronic Kidney Disease Unmet Needs 11. Anemia In Chronic Kidney Disease Emerging Therapies 12. Anemia In Chronic Kidney Disease Market Outlook 13. Country-Wise Anemia In Chronic Kidney Disease Market Analysis (2020–2034) 14. Anemia In Chronic Kidney Disease Market Access and Reimbursement of Therapies 15. Anemia In Chronic Kidney Disease Market Drivers 16. Anemia In Chronic Kidney Disease Market Barriers 17. Anemia In Chronic Kidney Disease Appendix 18. Anemia In Chronic Kidney Disease Report Methodology 19. DelveInsight Capabilities 20. Disclaimer 21. About DelveInsight About DelveInsight DelveInsight is a leading Healthcare Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefit from market analysis to accelerate business growth and overcome challenges with a practical approach. Media Contact Company Name: DelveInsight Contact Person: Jatin Vimal Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: Nevada Country: United States Website:
