21-07-2025
This system is critical to Americans' health. We must defend it.
Eric J. Rubin is editor in chief of the New England Journal of Medicine and the NEJM Group. Kirsten Bibbins-Domingo is editor in chief of JAMA and the JAMA Network.
When KJ Muldoon was born, he seemed healthy. But within days, doctors discovered he had a rare genetic condition that could allow toxic levels of ammonia to build up in his body, putting him at risk for brain damage or even death. The infant's doctors developed a first-of-its-kind therapy just for him, using CRISPR — a gene-editing technology that has been refined for use through decades of research and peer-reviewed science published in medical journals.