Latest news with #FSH
News18
11 hours ago
- Health
- News18
IVF And Miscarriage: Why 'Knowing Your Numbers' Matters
Last Updated: When you are going through IVF, inquire with your doctor about the statistics that are of the greatest importance to your specific situation Couples who undergo the procedure of IVF (In Vitro Fertilization) hope that in such a way their family will be expanded, but at the same time there are fears and doubts. Miscarriage is one of the most emotionally traumatic process setbacks. Although a woman could miscarry at any pregnancy, the loss may have deeper emotional effects at IVF since every cycle would be associated with much physical, emotional, and financial resources. Getting to grips with the factors that may cause miscarriage and what might perhaps prevent it involves going deeper into, what many patients do not give much attention to; their numbers. These are levels of hormones, quality of an embryo, chromosomal measurements and measures of uterine health. It is about being informed, it is about being empowered, with regards to saying that you know your numbers. 1. Hormonal Balance- The Puzzling Piece of the Jigsaw Such hormones as AMH (Anti-Mullerian Hormone), FSH (Follicle-Stimulation Hormone), LH (Luteinizing Hormone), progesterone, and estradiol are involved mainly in the quality of eggs, the thickness of endometrium, and embryo implantation. The abnormal levels may decrease the success rate or in some cases will cause miscarriage. These interventions are made possible by regular monitoring, which enables fertility specialists to modify protocols and address imbalances before they can progress. 2. Genetic testing and Embryo Quality Not every embryo is genetic viable. PGT-A could screen out aneuploid embryos and could determine chromosomally normal embryos, which were more likely to result in successful pregnancy. This is of great significance to the women who are past the age of 35 where their chances of several chromosomal abnormalities are very high hence the risk of miscarriage is high too. 3. The Uterus Conducting Environment Implantation and maintenance of pregnancy may be influenced by such structural problems as fibroids, polyps, or thin endometrium. Information about the thickness of the uterus lining, the flow patterns of the blood in your body, and anatomical defects is important prior to the embryo transfer. These problems can be identified with the help of imaging devices such as hysteroscopy or sonohysterography. 4. Blood clotting disorders and thyroid Function Thyroid syndrome and blood clotting disorders are mainly cured with the help of conventional medicine, which consists of the procedure of removal of the thyroid hormones. Recurrent pregnancy loss is known to be caused by thyroid dysfunction, as well as by such clotting disorders as anti-phospholipid syndrome or thrombophilia not diagnosed previously. These risks can be administered through simple blood tests, and when intervention is made early, the drug can highly benefit the outcome. 5. Individualization of IVF procedures Each person is distinct and IVF is not a treatment that fits all. Where you monitor the personal reactions made by your body this could be the way you consistently react to the stimulation medication to the manner your lining accumulates so that you as well as your doctor would adjust the protocols to achieve optimal results. Although miscarriage is in some cases inevitable, the chances of miscarriage can be minimized by knowing your numbers and gaining success in doing the IVF. It will allow you and your fertility considerations to make wiser and individual decisions. It is such a journey that every step is important and in such a journey knowledge is power. When you are going through IVF, inquire with your doctor about the statistics that are of the greatest importance to your specific situation, and do not back off asking second opinions or additional research. Since there are times when a missed value contributes to the difference between the heartbreak and cradling your baby in your arms. view comments Location : New Delhi, India, India First Published: July 29, 2025, 18:16 IST News lifestyle » health-and-fitness IVF And Miscarriage: Why 'Knowing Your Numbers' Matters Disclaimer: Comments reflect users' views, not News18's. Please keep discussions respectful and constructive. Abusive, defamatory, or illegal comments will be removed. News18 may disable any comment at its discretion. By posting, you agree to our Terms of Use and Privacy Policy.
Business Standard
10-07-2025
- Business
- Business Standard
SRMIST Faculty of Science and Humanities Hosts Induction for 2025-26 Batch
HT Syndication Kattankulathur (Tamil Nadu) [India], July 10: "Transitioning from school to higher education is a big step, often filled with questions and uncertainty," says Prof. C. Muthamizhchelvan, Vice Chancellor, SRMIST-KTR, during the Induction Ceremony organised by the Faculty of Science and Humanities (FSH), SRM Institute of Science and Technology (SRMIST), Kattankulathur. The event welcomed over 2,600 newly admitted undergraduate and postgraduate students for the academic year 2025-26. Held at the Dr. T. P. Ganesan Auditorium, the ceremony marked the beginning of the students' academic journey. The Chief Guest, Lt. Gen. Fernandez, AVSM, VSM, Commandant, Officers Training Academy (OTA), Chennai, delivered an insightful address, encouraging students to embrace discipline, resilience, and service throughout their time at SRMIST. In his welcome address, Dr. A. Duraisamy, Dean of FSH, spoke about the faculty's interdisciplinary strengths and academic diversity. With 33 undergraduate and 23 postgraduate programmes across disciplines such as Computer Science, Media Studies, Literature, Biotechnology, Commerce, Psychology, Economics, Defence Studies, and Fashion Designing, FSH continues to foster holistic and career-oriented education. Prof. C. Muthamizhchelvan, Vice Chancellor, SRMIST, said, "Among over 12,000 universities in the country, your choice reflects your trust in our vision. SRMIST stands tall with its diverse student body, flexible curriculum, and vibrant learning environment. While your CGPA matters, what truly shapes you is what you learn beyond the classroom. You are now an integral part of our journey forward." Prof. A. Vinay Kumar, Pro Vice-Chancellor (FSH, Management, Law), highlighted the importance of staying industry-ready through continuous skill development: "The transition from classroom to industry comes with a skill gap, and it's our duty to bridge it. At SRMIST, we have adopted the National Education Policy 2020 to offer multidisciplinary learning and minor courses to help students upskill and stay relevant. With 18 minor programmes now available, we are equipping students to think beyond a single discipline. In today's fast-changing world, upskilling and reskilling are not optional, they are essential." Lt. Gen. Michael A.J. Fernandez added: "You couldn't be in a better institution. SRMIST offers immense scope to learn, grow, and define your path. It's never too early or too late to reflect on your goals; think deeply about what you want from your course and pursue it with intent. Build a solid routine, it is your compass. Balance academics with personal development, prioritise fitness, and cultivate habits that last. Read, write, speak, and stay curious." He also recommended the book The 7 Habits of Highly Effective People, highlighting a key takeaway: "Focus on what's important, not just what's urgent." The induction programme served as a significant stepping stone to the university's academic environment, values, infrastructure, and opportunities, laying the groundwork for a meaningful and successful academic journey for the new cohort. SRM Faculty of Science & Humanities (SRMFSH) SRM Faculty of Science and Humanities (SRMFSH) at SRMIST, Kattankulathur, Chennai is a diverse academic hub comprising 22 departments and over 6,000 students. Backed by 200 faculty members and 180 research scholars, FSH offers a comprehensive range of programs at the undergraduate, postgraduate, and doctoral levels, including B.A., BCA, M.A., M.S., MSW, MCA, and Ph.D. in disciplines such as AI, Data Science, Computer Applications, Biotechnology, Physics, Biomedical Science, Visual Communication, Psychology, Fashion Designing, Chemistry, Mathematics, Defence and Strategic Studies, Statistics, Economics, Physical Education, Commerce, Accounting and Finance, Professional Accounting, Strategic Finance, Information Systems and Management, Corporate Secretaryship, Journalism and Mass Communication, English and Yoga. With a strong focus on interdisciplinary learning, research, and social responsibility, FSH nurtures intellectual curiosity and creativity across science, technology, and the humanities. More details are available at ABOUT SRMIST SRM Institute of Science and Technology (SRMIST) is a multidisciplinary university recognised with an A++ accreditation by NAAC and classified as a Category I university with 12B status by UGC/MoE. In the 2024 NIRF rankings, SRMIST secured the 12th position nationally and holds a global '4 Star' rating from QS, along with the India-centric QS IGAUGE Diamond rating. Driven by a commitment to academic excellence, research innovation, and global outlook, SRMIST-KTR has emerged as one of India's most vibrant knowledge ecosystems. With over 500 active labs, ₹270+ crore in external funding, 600+ funded projects, and more than 53,000 research publications, SRMIST is a research-intensive institution. For more information, visit
India Gazette
10-07-2025
- Science
- India Gazette
SRMIST Faculty of Science and Humanities Hosts Induction for 2025-26 Batch
HT Syndication Kattankulathur (Tamil Nadu) [India], July 10: 'Transitioning from school to higher education is a big step, often filled with questions and uncertainty,' says Prof. C. Muthamizhchelvan, Vice Chancellor, SRMIST-KTR, during the Induction Ceremony organised by the Faculty of Science and Humanities (FSH), SRM Institute of Science and Technology (SRMIST), Kattankulathur. The event welcomed over 2,600 newly admitted undergraduate and postgraduate students for the academic year 2025-26. Held at the Dr. T. P. Ganesan Auditorium, the ceremony marked the beginning of the students' academic journey. The Chief Guest, Lt. Gen. Fernandez, AVSM, VSM, Commandant, Officers Training Academy (OTA), Chennai, delivered an insightful address, encouraging students to embrace discipline, resilience, and service throughout their time at SRMIST. In his welcome address, Dr. A. Duraisamy, Dean of FSH, spoke about the faculty's interdisciplinary strengths and academic diversity. With 33 undergraduate and 23 postgraduate programmes across disciplines such as Computer Science, Media Studies, Literature, Biotechnology, Commerce, Psychology, Economics, Defence Studies, and Fashion Designing, FSH continues to foster holistic and career-oriented education. Prof. C. Muthamizhchelvan, Vice Chancellor, SRMIST, said, 'Among over 12,000 universities in the country, your choice reflects your trust in our vision. SRMIST stands tall with its diverse student body, flexible curriculum, and vibrant learning environment. While your CGPA matters, what truly shapes you is what you learn beyond the classroom. You are now an integral part of our journey forward.' Prof. A. Vinay Kumar, Pro Vice-Chancellor (FSH, Management, Law), highlighted the importance of staying industry-ready through continuous skill development: 'The transition from classroom to industry comes with a skill gap, and it's our duty to bridge it. At SRMIST, we have adopted the National Education Policy 2020 to offer multidisciplinary learning and minor courses to help students upskill and stay relevant. With 18 minor programmes now available, we are equipping students to think beyond a single discipline. In today's fast-changing world, upskilling and reskilling are not optional, they are essential.' Lt. Gen. Michael A.J. Fernandez added: 'You couldn't be in a better institution. SRMIST offers immense scope to learn, grow, and define your path. It's never too early or too late to reflect on your goals; think deeply about what you want from your course and pursue it with intent. Build a solid routine, it is your compass. Balance academics with personal development, prioritise fitness, and cultivate habits that last. Read, write, speak, and stay curious.' He also recommended the book The 7 Habits of Highly Effective People, highlighting a key takeaway: 'Focus on what's important, not just what's urgent.' The induction programme served as a significant stepping stone to the university's academic environment, values, infrastructure, and opportunities, laying the groundwork for a meaningful and successful academic journey for the new cohort. SRM Faculty of Science & Humanities (SRMFSH) SRM Faculty of Science and Humanities (SRMFSH) at SRMIST, Kattankulathur, Chennai is a diverse academic hub comprising 22 departments and over 6,000 students. Backed by 200 faculty members and 180 research scholars, FSH offers a comprehensive range of programs at the undergraduate, postgraduate, and doctoral levels, including B.A., BCA, M.A., M.S., MSW, MCA, and Ph.D. in disciplines such as AI, Data Science, Computer Applications, Biotechnology, Physics, Biomedical Science, Visual Communication, Psychology, Fashion Designing, Chemistry, Mathematics, Defence and Strategic Studies, Statistics, Economics, Physical Education, Commerce, Accounting and Finance, Professional Accounting, Strategic Finance, Information Systems and Management, Corporate Secretaryship, Journalism and Mass Communication, English and Yoga. With a strong focus on interdisciplinary learning, research, and social responsibility, FSH nurtures intellectual curiosity and creativity across science, technology, and the humanities. More details are available at ABOUT SRMIST SRM Institute of Science and Technology (SRMIST) is a multidisciplinary university recognised with an A++ accreditation by NAAC and classified as a Category I university with 12B status by UGC/MoE. In the 2024 NIRF rankings, SRMIST secured the 12th position nationally and holds a global '4 Star' rating from QS, along with the India-centric QS IGAUGE Diamond rating. Driven by a commitment to academic excellence, research innovation, and global outlook, SRMIST-KTR has emerged as one of India's most vibrant knowledge ecosystems. With over 500 active labs, 270+ crore in external funding, 600+ funded projects, and more than 53,000 research publications, SRMIST is a research-intensive institution. For more information, visit (ADVERTORIAL DISCLAIMER: The above press release has been provided by HT Syndication. ANI will not be responsible in any way for the content of the same)
Hindustan Times
09-07-2025
- Health
- Hindustan Times
Fertility specialists explain how trending diets like keto and intermittent fasting impact men and women differently
Did you know intermittent fasting and diets like keto diet can have distinct effects on men and women, particularly when it comes to fertility? If you're considering intermittent fasting or keto diet, especially if you're trying to conceive, it's crucial to consult with a healthcare professional to discuss potential risks and benefits and determine the best approach for your individual needs. Here's what fertility specialists have to say. Also read | About to start keto diet? 5 important things you need to know for best results Before starting any new diet, especially if you're trying to conceive, consult a doctor. (Freepik) How does keto diet impact women and men's fertility? Dr Navina Singh, fertility specialist at Birla Fertility and IVF, Mumbai said, 'When we talk about trending diets like keto and intermittent fasting, it's important to remember that most people turn to them for weight loss or to improve their overall health. But when it comes to fertility, the effects aren't always straightforward. They can help in some cases, but not all, and the impact can look quite different for men and women." Dr Singh said about the keto diet: 'It's a high-fat, low-carbohydrate diet with moderate protein. The aim is to push the body into a state called ketosis, where it starts burning fat for energy instead of carbohydrates. In women, especially those dealing with polycystic ovary syndrome (PCOS), this can be helpful. Keto can lower insulin resistance, which is a core issue in PCOS, and that, in turn, can help regulate hormones. In obese women or those with insulin-related reproductive problems, this can sometimes lead to more regular ovulation and better chances of conception. In men, too, weight loss through keto may help improve testosterone levels, which could benefit sperm quality.' Dr Alimileti Jhansi Rani, fertility specialist at Birla Fertility and IVF, Hyderabad added about the keto diet: 'It's been studied more in the context of PCOS. There are small studies showing improvements in things like blood sugar control, weight loss, and even hormone levels related to ovulation. Some women also report better skin, less hair loss, and even feeling more balanced overall. In men, keto has been linked to better sperm quality, in terms of motility and morphology.' But there are drawbacks to keep in mind. 'Cutting out carbs too drastically can affect reproductive hormones like FSH and LH. And if the diet isn't nutritionally balanced, it can lead to deficiencies in important nutrients such as folate and iron, which are essential during pregnancy. We've also seen women report irregular or missed periods after starting keto, often linked to sudden weight loss and hormonal shifts,' Dr Singh said. Intermittent fasting can be an effective way to improve health, but it's essential to approach it safely and responsibly.(Shutterstock) How intermittent fasting affects women and men Dr Singh explained how intermittent fasting is a bit different: 'It usually involves eating only during a set window and fasting for the rest of the day. The main benefit again is weight loss. For women with PCOS, it may help reduce inflammation, improve insulin sensitivity, and bring some hormonal balance back, all of which can support fertility. But fasting for too long or being too restrictive can cause oestrogen levels to drop, which might disrupt ovulation or even stop periods altogether. In men, intermittent fasting may initially boost testosterone and sperm health, especially when it helps manage weight or blood sugar. But over time, if it's too extreme, it could have the opposite effect.' Dr Rani further shared, 'When we talk about intermittent fasting, we usually think of it as a way to manage weight or blood sugar, but it's starting to show some promise for reproductive health too. While there is a need for larger and better research on the subject, there seems to be ways these diets help with overall fertility." She added, 'In men, too, intermittent fasting might improve fertility. Some studies indicate better sperm count and motility, especially when fasting leads to weight loss or better metabolic health. But again, more research is needed before we recommend it specifically for that purpose.' Dr Rani added, 'There's also growing interest in how fasting might affect the gut microbiome, which we now know plays a big role in hormonal regulation. Some studies suggest intermittent fasting can improve the diversity and composition of gut microbes, which could in turn support better hormonal balance. And then there's the circadian rhythm. Eating in sync with the body's internal clock, like consuming food earlier in the day, might boost some of these positive effects.' Should you follow a diet at all? According to Dr Singh, while both keto and intermittent fasting can offer fertility benefits in specific contexts, they should be approached with caution, not too rigidly, and ideally with medical guidance. Dr Rani added: 'That said, both of these diets come with caveats. They're restrictive, they affect people differently, and they're definitely not one-size-fits-all. But for the right patient, particularly someone dealing with PCOS or metabolic issues, they might be worth considering, with proper medical guidance, of course.' Note to readers: This article is for informational purposes only and not a substitute for professional medical advice. Always seek the advice of your doctor with any questions about a medical condition.
National Post
03-07-2025
- Health
- National Post
Ferring ADAPT-1 Trial Builds on Dosing Evidence for Follitropin Delta
Article content Data presented today at the ESHRE congress builds evidence for conventional-based Follicular Stimulating Hormone (FSH) dosing for Rekovelle ® (follitropin delta); alongside its existing unique algorithm-based dosing Article content PARIS — Follitropin delta starting dose of 15 micrograms (µg)/day has comparable efficacy and safety as a starting dose of 225 International Units (IU)/day of follitropin alfa for ovarian stimulation in vitro fertilisation (IVF)/intracytoplasmic sperm injection (ICSI) gonadotrophin-releasing hormone (GnRH) antagonist protocol cycles. This is the key finding of a trial presented today at the European Society of Human Reproduction and Embryology (ESHRE) Congress in Paris and published in Human Reproduction. These data build on previous studies which have established an estimated point of clinical correspondence for 10 µg follitropin delta to 150 IU follitropin alfa in this class of medications. 1,2 The ADAPT-1 trial was a multicentre, randomised, assessor-blind study involving 300 women aged 18-40 years undergoing IVF or ICSI. 3 The trial compared the efficacy and safety of follitropin delta and follitropin alfa using conventional dosing regimens with a primary endpoint of number of oocytes retrieved. Article content Currently, follitropin delta is approved for use via a dosing algorithm based on serum anti-Müllerian Hormone (AMH) and bodyweight individualised for each patient, and aims to obtain an ovarian response which is associated with a favourable safety/efficacy profile. The clinical value of this approach has been well established 4,5,6,7,8, particularly in treatment-naïve patients where the algorithm aims to achieve 8–14 retrieved oocytes while minimising the risk of ovarian hyperstimulation syndrome (OHSS) to optimise the live birth rate in a fresh and frozen transfer cycle. 4,5,6,7,8 Key Findings: Ovarian Response: Both treatment groups achieved a mean of 9.9 oocytes retrieved, indicating similar efficacy Clinical Pregnancy Rates: Clinical pregnancy rates were similar for follitropin delta 31.6% versus 31.0% for follitropin alfa Drug Product Usage: After measurement unit conversion, the mean total dose patients were exposed to was numerically lower for follitropin delta (143.7±33.6 µg) than follitropin alfa (154.3±23.1 µg or 2,105±315 IU) OHSS Rates: Early OHSS rates were low (2.5% for follitropin delta and 3.0% for follitropin alfa), with no cycle cancellations due to excessive ovarian response on either arm of the study. Dr Andrea Bernabeu, Medical Director at Instituto Bernabeu and principal investigator of the ADAPT-1 trial, said: 'No patients we see as fertility doctors are the same and the ability to optimise therapy based on patients age, treatment goal and whether they have a high or low response to follicular stimulation are all relevant. These data provide confidence and expand our understanding for dosing in follitropin delta.' Article content Pierre-Yves Berclaz, Chief Science and Medical Officer at Ferring Pharmaceuticals, stated: 'The ADAPT-1 trial results confirm the efficacy and safety of follitropin delta across the full range of dosing strategies, making it the only recombinant FSH with robust clinical evidence supporting multiple dosing strategies. Ferring will take forward the implications of this study in future dialogue with regulatory authorities.' Article content About GnRH protocols Article content Gonadotrophin-releasing hormone (GnRH) agonists and antagonists are used as concomitant treatment during ovarian stimulation to prevent premature luteinisation and ovulation for IVF/ICSI. 7,8 About Follitropin Delta (Rekovelle ®) Follitropin delta is a human cell line-derived rFSH with an approved dosing algorithm designed for a predictable ovarian response. 3 It is the first rFSH derived from a human cell line (PER.C6 ® cell line). Follitropin delta is structurally and biochemically distinct from other existing rFSH gonadotrophins. 3,4 Follitropin delta is approved in certain markets for use in controlled ovarian stimulation for the development of multiple follicles in women undergoing assisted reproductive technologies (ART), such as IVF or ICSI cycle. The individualised dosing of follitropin delta is determined using an approved algorithm, based on a woman's AMH level and body weight. 3,5 AMH is a biomarker used to assess ovarian reserve and can help predict ovarian response. 5,6 The follitropin delta dose should be based on AMH level, measured using the ELECSYS AMH Plus immunoassay from Roche, the ACCESS AMH Advanced from Beckman Coulter, or LUMIPULSE G AMH from Fujirebio. 3 About Ferring Pharmaceuticals Ferring Pharmaceuticals is a privately owned, research-driven, specialty biopharmaceutical group committed to building families and helping people live better lives. We are leaders in reproductive medicine with a strong heritage in areas of gastroenterology and urology, and are at the forefront of innovation in uro-oncology gene therapy. Ferring was founded in 1950 and employs more than 7,000 people worldwide. The company is headquartered in Saint-Prex, Switzerland, and has operating subsidiaries in more than 50 countries which market its medicines in over 100 countries. Article content REFERENCES Article content 1 – Arce JC, Larsson P, Garcia-Velasco JA; Establishing the follitropin delta dose that provides a comparable ovarian response to 150 IU/day follitropin alfa; RBMO; 2020 Article content 2 – Yang R, Zhang Y, Liang X et al; Comparative clinical outcome following individualized follitropin delta dosing in Chinese women undergoing ovarian stimulation for in vitro fertilization / intracytoplasmic sperm injection; Reproductive Biology and Endocrinology; 2022 Article content 3 – Clinical page: (Accessed June 2025) Article content 4 – Andersen, A. N., Nelson, S. M., Fauser, B. et al. (2017). Individualized versus conventional ovarian stimulation for in vitro fertilization: A multicenter, randomized, controlled, assessor-blinded, phase 3 noninferiority trial. Fertility and Sterility, 107(2), 387-396. Article content 5 – Bosch E, Havelock J, Martin FS, Rasmussen BB, Klein BM, Mannaerts B, Arce JC; ESTHER-2 Study Group. Follitropin delta in repeated ovarian stimulation for IVF: a controlled, assessor-blind Phase 3 safety trial. Reprod Biomed Online. 2019 Feb;38(2):195-205. PMID: 30594482. Article content 6 – Ishihara O, Arce JC, Japanese Follitropin Delta Phase 3 Trial G. Individualized follitropin delta dosing reduces OHSS risk in Japanese IVF/ICSI patients: a randomized controlled trial. Reprod Biomed Online. 2021 May;42(5):909-18. PubMed PMID: 33722477. Epub 2021/03/17. Article content 7 – Qiao J, Zhang Y, Liang X, et al. A randomised controlled trial to clinically validate follitropin delta in its individualised dosing regimen for ovarian stimulation in Asian IVF/ICSI patients. Hum Reprod. 2021 Jun 28;36(9):2452-62. PubMed PMID: 34179971. Epub 2021/06/29. Article content 8 – Blockeel C, Griesinger G, Rago R, et al. Prospective multicenter non-interventional real-world study to assess the patterns of use, effectiveness and safety of follitropin delta in routine clinical practice (the PROFILE study). Frontiers in Endocrinology. 2022 Dec 22;13:992677. PMID: 36619578. Article content Article content Article content Article content Article content Contacts Article content For more information, please contact Article content M Article content atthew Worrall Article content Article content Article content Article content
