Latest news with #Flare
Business Wire
2 days ago
- Business
- Business Wire
Dispatch Bio Launches to Deliver Universal Treatment Across Solid Tumors with Novel Immunotherapy Approach
PHILADELPHIA & SAN FRANCISCO--(BUSINESS WIRE)--Dispatch Bio announced its official launch today, with a mission to engineer a universal treatment across solid tumors, which represent approximately 90% of cancers worldwide. Immunotherapies have struggled to effectively treat solid tumors due to two main challenges: the lack of a tumor-specific target and the presence of an immune-suppressive tumor microenvironment. Dispatch's first-in-class Flare platform was specifically engineered to overcome both. It works by delivering a viral vector carrying a novel, universal antigen – called Flare – that precisely tags solid tumor cells while simultaneously breaking down the tumor's inhibitory environment. Once in place, the Flare antigen acts as a beacon, directing the immune system to find and clear the cancer cells — without harming healthy tissue. 'At Dispatch, we are leveraging the ideal tumor target – one that is only expressed by the tumor cells in a patient – and advances in cell therapy engineering and immune system activation at the right place, at the right time, to get to deep and durable responses in cancer,' said Sabah Oney, Ph.D., Chief Executive Officer of Dispatch. 'This work matters deeply to me, as it does to so many whose lives have been touched by cancer. We've built a strong scientific foundation, assembled an exceptional team and developed innovative technology that give us a real shot at making a difference. We are fully committed to doing everything we can for patients who urgently need new options.' Dispatch was established through a pivotal collaboration with the Parker Institute for Cancer Immunotherapy (PICI) and convergence of groundbreaking technologies from the laboratories of Andy Minn, M.D., Ph.D.; Carl June, M.D.; Chris Garcia, Ph.D.; and Kole Roybal, Ph.D. 'With this confluence of innovative technologies from the labs across PICI, we are poised to shift how cancer therapies are conceived,' said Sean Parker, founder and chairman of PICI, as well as a member of Dispatch's board of directors. "We can now pursue the ultimate goal – a universal cure for most solid tumor cancers – using cutting-edge modalities.' Renowned Leadership and Pioneering Scientists Since its founding in 2022, Dispatch has focused on building a world-class leadership team and executing its broad pipeline of programs. The founding team at Dispatch includes: Scientific Co-Founders Andy Minn, M.D., Ph.D., Chair of Immuno-Oncology at Memorial Sloan Kettering Cancer Center Carl June, M.D., PICI Center Director and the Richard W. Vague Professor in Immunotherapy in the Perelman School of Medicine at the University of Pennsylvania Chris Garcia, Ph.D., Professor of Structural Biology and Molecular and Cellular Physiology at Stanford School of Medicine, Stanford University Kole Roybal, Ph.D., PICI Center Director and Professor of Microbiology and Immunology at University of California, San Francisco Board of Directors Jeff Marrazzo, Chairman; Co-founder and Former CEO, Spark Therapeutics Jake Bauer, Venture Partner, ARCH Venture Partners John Connolly, Ph.D., Chief Scientific Officer, PICI Robert Nelsen, Co-founder and Managing Director, ARCH Venture Partners Sabah Oney, Ph.D., Chief Executive Officer, Dispatch Sean Parker, Founder and Chairman, PICI Steve Gillis, Ph.D., Managing Director, ARCH Venture Partners Leadership Team Sabah Oney, Ph.D., Chief Executive Officer Barbra Sasu, Ph.D., Chief Scientific Officer Chris Wiwi, Ph.D., Senior Vice President, Technical Operations Jennifer Flaisher, Chief People and Culture Officer Lex Johnson, Ph.D., Co-Founder and Chief Platform Officer Naveen Bazaj, Senior Vice President, Corporate Development Scientific Advisory Board Kole Roybal, Ph.D., University of California, San Francisco; SAB Chairman Andy Minn, M.D., Ph.D., Memorial Sloan Kettering Cancer Center Antoni Ribas, M.D., Ph.D., University of California, Los Angeles Anusha Kalbasi, M.D., Stanford University Brad Rosenberg, M.D., Ph.D., Icahn School of Medicine at Mount Sinai Carl June, M.D., University of Pennsylvania Chris Garcia, Ph.D., Stanford University Christine Brown, Ph.D., City of Hope David Kirn, M.D., 4D Molecular Therapeutics; University of California, Berkeley John Connolly, Ph.D., PICI Kristen Hege, M.D., University of California, San Francisco Lisa Coussens, M.D., Ph.D., FAACR, Oregon Health & Science University Matt Porteus, M.D., Ph.D., Stanford University Series A Funding to Support First-in-Human Studies The Series A syndicate includes founding investors ARCH Venture Partners and PICI, along with Bristol Myers Squibb, the University of Pennsylvania, Stanford University, and Alexandria Venture Investments. With this recently closed funding round, Dispatch has raised a total of $216 million to date. Proceeds from the financing will be used to advance the company's therapeutic candidates into first-in-human clinical studies and beyond, with the first program expected to enter the clinic in 2026. 'We are on the wave of a revolution in cancer therapy, where innovations like Dispatch's tumor-agnostic approach to immunotherapy have the potential to treat a majority of solid tumors,' said Steve Gillis, Ph.D., board member of Dispatch and managing director at ARCH Venture Partners. 'We are excited to support the Dispatch team as they continue to advance their programs.' About Dispatch Bio Established in 2022, Dispatch Bio was founded with a bold purpose: to help create a world where all cancer patients can be cured. To achieve this, the company is engineering a universal treatment across solid tumors, leveraging its first-in-class Flare platform. This novel approach combines the strengths of immunotherapy with a tumor-specific viral vector, both engineered to clear tumor cells with precision and power. Dispatch has operations in Philadelphia and San Francisco, with access to world-class researchers. To learn more, visit and follow us on LinkedIn and X. About the Parker Institute for Cancer Immunotherapy (PICI) The Parker Institute for Cancer Immunotherapy (PICI) is a 501c3 nonprofit organization driving the next generation of cancer treatment by accelerating the development of breakthrough immune therapies to turn all cancers into curable diseases. Founded in 2016 through the vision of Sean Parker, PICI unites the nation's top cancer centers into a collaborative consortium that fuels high-risk, high-reward science with shared goals, data, and infrastructure. Unlike traditional research models, PICI goes beyond discovery by actively advancing promising innovations through clinical testing, company formation and incubation, and commercialization. PICI has supported more than 1,000 investigators across its network and has a portfolio that includes 17 biotech ventures with over $4B raised in capital. PICI is uniquely positioned to close the gap between scientific discovery and patient access. By integrating scientific excellence with entrepreneurial execution, PICI is reimagining how cures are made, and accelerating their path to the people who need them most. Learn more at About ARCH Venture Partners ARCH Venture Partners creates and invests in groundbreaking life science and technology companies. The firm is a recognized leader in commercializing technologies developed at academic institutions, corporate research groups and national laboratories. ARCH invests primarily in companies it co-founds with leading scientists and entrepreneurs, bringing innovations in life sciences and physical sciences to market. For more information, visit
Yahoo
09-07-2025
- Business
- Yahoo
VivoPower International, Flare Partner to Generate Yield on $100M in XRP
VivoPower International (NASDAQ:VVPR) is one of the best-performing NASDAQ stocks according to analysts. On June 11, VivoPower announced a definitive partnership with Flare. The collaboration aims to generate yield on VivoPower's digital assets, beginning with an initial deployment of $100 million in XRP. The move serves as a validation of the XRP ecosystem's utility for institutional treasury management. The XRP ecosystem is a digital payment network built around the XRP Ledger/XRPL. VivoPower will generate yield through protocols on the Flare Network, such as Firelight, and will reinvest this income directly back into XRP holdings. A technician inspecting a modern battery cell. The partnership also delivers the first institutional-scale validation of Flare's FAssets system, which establishes it as a programmable utility layer for the XRP ecosystem. FAssets is a non-custodial protocol that allows XRP to be used in smart contract applications while preserving its native security model. VivoPower International (NASDAQ:VVPR) provides energy solutions for customized & ruggedized fleet applications, battery & microgrids, and solar and critical power technology & services. Flare is a next-gen Layer 1 blockchain designed to connect decentralized systems with real-world utility through secure and data-rich interoperability. While we acknowledge the potential of VVPR as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the . READ NEXT: and . Disclosure: None. This article is originally published at Insider Monkey.
Yahoo
17-06-2025
- Business
- Yahoo
XRP Gets Another DeFi Boost Through Flare's FAssets and FXRP, Messari Says
Flare Network is helping push XRP deeper into decentralized finance (DeFi) with FXRP — a fully collateralized, non-custodial representation of XRP on Songbird — and a growing suite of infrastructure now drawing interest from retail and institutional players alike, according to a Messari report. Flare validates off-chain data without external middleware. The framework secures FAssets, such as FXRP, and enables cross-chain transactions, which is key to building a decentralized financial ecosystem around XRP. At the protocol layer, FXRP minting utilizes a multi-collateral system, pooling stablecoins, FLR, and agent funds, to maintain a 2x or greater over-collateralization ratio. All participating agents are KYC'd and monitored on-chain, adding a layer of compliance uncommon in DeFi bridges. While FXRP is currently live on Songbird (Flare's canary network), the mainnet rollout is reportedly near. In blockchain parlance, a canary network is designed for testing new features and protocols before they are deployed to a main network, but operates as a fully functional, live network (unlike a testnet, where assets don't hold any financial value). Interest is already picking up: Trading platform Uphold, which holds 1.8 billion XRP, is looking to integrate FXRP. Separately, Nasdaq-listed VivoPower has committed $100 million in XRP for deployment on the Flare network. Next in line is liquid staking. Firelight Protocol plans to launch stXRP, a liquid staking derivative for FXRP. Modeled after stETH, the token will be transferable across Flare's DeFi apps and allow holders to maintain liquidity while earning rewards, further expanding XRP's use case on the network. If the launch plays out as designed, Flare may finally bring DeFi utility to one of crypto's most held, but underutilized, tokens. 'While the XRPL has native functions like escrows, checks, and payment channels, it cannot implement complex smart contracts,' Messari analysts said in the report. 'FAssets bridge this gap by allowing XRP token holders to participate in a full range of DeFi activities (aka XRPFi), such as lending, borrowing, yield farming, and liquidity provisioning, without sacrificing custody of their underlying is particularly significant for XRP, which has historically been limited in its DeFi applications despite its substantial market capitalization and global adoption,' the analysts added. For institutions, XRPFi offers a way to generate yield on their XRP holdings, which have traditionally been held as static assets.
Business Insider
12-06-2025
- Business
- Business Insider
BitGo Introduces Custody Support for Flare and Songbird Networks
Dubai, UAE, June 12th, 2025, Chainwire Flare, the blockchain for data, today announced that BitGo has launched institutional custody services for Flare (FLR) and Songbird (SGB). BitGo, a globally regulated and licensed qualified custodian based in the United States, provides secure storage infrastructure used by many leading digital asset platforms and financial firms. This collaboration represents a meaningful step forward as Flare expands its reach to regulated and compliance-focused markets. Institutions using BitGo can now store and manage FLR and SGB tokens through qualified custody or self-custody setups. Both hot and cold wallet options are available, offering flexibility for institutions managing these assets. Staking functionality and additional integrations will follow in the coming months. Flare is an EVM-compatible Layer 1 network designed to support applications that rely on real-world data. It features built-in data protocols such as the Flare Time Series Oracle for delivering accurate price feeds, the Flare Data Connector for integrating external and cross-chain information, and the FAssets system, which brings assets like BTC, XRP, and DOGE into the world of decentralized finance. Songbird, Flare's canary network, operates as a real-time testbed for new features before they are introduced on the Flare mainnet. Developers use Songbird to evaluate functionality under live conditions with real economic incentives. The announcement comes as Flare gains momentum in institutional circles. Earlier this week, VivoPower, a publicly traded firm, became the first major institution to adopt an XRP-based treasury strategy on Flare, allocating one hundred million dollars worth of XRP to the network's DeFi ecosystem. 'Partnering with a well-established, U.S.-based qualified custodian like BitGo is a key milestone in Flare's institutional journey,' said Hugo Philion, CEO and co-founder of Flare. 'BitGo's reputation, regulatory credentials, and support for segregated accounts make them an ideal partner as we prepare to launch products that require compliant custody solutions. We're proud to work with BitGo to expand secure access to FLR and SGB for institutions worldwide.' In the coming period, BitGo will introduce staking for FLR, delegation support for Wrapped Flare (WFLR), integration with Flare's token standard, and compatibility with the Flare P-Chain. Institutions seeking to engage with FLR and SGB through BitGo can reach out to their client service manager or visit the BitGo website for onboarding details. Flare is a smart contract platform built to bring external data on-chain securely and at scale. It supports data-intensive use cases including machine learning, asset tokenization, gaming, and social platforms. With enshrined oracles integrated directly into its network, Flare enables developers to access a wide range of data sources while maintaining decentralization and trust minimization. BitGo is a United States based digital asset custodian serving institutions and exchanges across the globe. Recognized for its regulatory standing and compliance credentials, BitGo offers custody solutions including segregated accounts and qualified custodianship. The company is licensed by the New York Department of Financial Services and provides services designed to meet the needs of professional digital asset holders.
Yahoo
11-06-2025
- Business
- Yahoo
VivoPower to Deploy $100M in XRP on Flare, Add Ripple USD for Treasury Operations
VivoPower International (VVPW), the Nasdaq-listed company transitioning into a digital asset treasury play, has plans to put $100 million worth of XRP XRP tokens to work. The firm announced Wednesday it has partnered with layer-1 blockchain Flare FLR to deploy $100 million XRP to generate yield on its treasury holdings. The initiative marks the first large-scale use of Flare's FAssets system, which enables non-smart contract tokens like XRP to interact with decentralized finance (DeFi) protocols, the press release said. VivoPower plans to generate yield through Flare-native protocols such as Firelight and reinvest the income to expand its XRP holdings. The company said it will also adopt payment firm Ripple's RLUSD stablecoin as its cash-equivalent reserve. "It's no longer enough to simply hold XRP; the duty to our shareholders is to make it productive," CEO and executive chairman Kevin Chin said in a statement. "Adopting Ripple's RLUSD is a cornerstone of this strategy, providing the stability and compliance this next-generation treasury demands." For Flare, the deal is a milestone of institutional validation, Flare co-founder Hugo Philion pointed out. "Our FAssets system [...] is more than just a bridge; it's a gateway that allows institutions to bring assets like XRP into programmable DeFi environments to generate yield, all while retaining their fundamental security," he said. VivoPower is part of the growing roster of public firms raising money to purchase and add digital assets to their treasuries, a playbook popularized by Michael Saylor's Strategy (MSTR) that has become the largest corporate holder of bitcoin BTC. The firm's latest move comes shortly after tapping BitGo's over-the-counter trading desk for acquiring an initial $100 million trench of XRP tokens. VivoPower last month said that it entered into an agreement for a $121 million private share placement, with the fundraising led by Saudi Prince Abdulaziz bin Turki Abdulaziz Al Saud, chairman of Eleventh Holding Company, according to a SEC filing. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
