Latest news with #Frommer
Yahoo
29-05-2025
- Business
- Yahoo
Morgan Stanley Maintains Buy Rating on Bicara (BCAX) After the Ficerafusp Alfa Trial Update
On May 23, Judah Frommer from Morgan Stanley maintained a Buy rating on Bicara Therapeutics Inc. (NASDAQ:BCAX) while keeping the price target at $36. This comes after the company released its interim data from Phase 1/1b trial of Ficerafusp alfa, which is the company's lead asset and a first-in-class bifunctional antibody. Close-up of a scientist in a lab conducting tests on a humanized immunoglobulin G1. Bicara Therapeutics Inc. (NASDAQ:BCAX) is a clinical-stage biopharmaceutical company that develops innovative bifunctional antibody therapies for solid tumors. Ficerafusp alfa is being tested for enhanced tumor penetration and to overcome the immunosuppressive tumor microenvironment, which has historically limited treatment efficacy in solid tumors. The recent data from the Phase 1/1b study has shown promising results in treating HPV-negative patients who have head and neck squamous cell carcinoma. The analyst highlighted that the trial reported a median overall survival exceeding 20 months, including an 18-21% complete response rate. Frommer believes this is a significant improvement compared to standard care, suggesting that approval of Ficerafusp alfa could be a breakthrough in a challenging therapeutic area. While we acknowledge the potential of BCAX as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than BCAX and that has 100x upside potential, check out our report about the . READ NEXT: and . Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Boston Globe
22-03-2025
- Business
- Boston Globe
States team up to defend green transportation projects targeted by Trump
'These are changes we need to make anyway, but they're more urgent than ever,' said Justin Balik, senior state program director for the environmental advocacy group Evergreen Action and one of the organizers of the Clean Rides Network. 'I've been calling the state departments of transportation the next frontier of climate advocacy.' Get Starting Point A guide through the most important stories of the morning, delivered Monday through Friday. Enter Email Sign Up Trading highway expansion for buses Advertisement Although Colorado wasn't among the seven charter members of the Clean Rides Network, a policy enacted there set the framework for one of its most ambitious goals. In 2021, Gov. Jared Polis committed to a dramatic reduction in Colorado's greenhouse gas emissions and employed a novel approach to accelerate the timeline. Whenever the state's transportation department commits money to a large-scale project that increases vehicle traffic such as a new highway, it must also pursue a corresponding project to offset the environmental harms. Two major highway expansion projects were canceled because of the policy, said Matt Frommer of the Southwest Energy Efficiency Project. The group advocated for the change. Colorado used the savings to expand an intercity bus service that has soared in popularity for urban residents and tourists traveling to ski resorts. Polis' vision lined up with the multimodal transportation aims under the $1.1 trillion bipartisan infrastructure law Biden signed that year. In the final months of Biden's administration, the city of Denver won a $150 million federal grant to build a rapid transit bus line along one of its busiest corridors. Frommer, a transportation and land use policy manager, said there are fears that states will now have to pursue projects like that on their own. Advertisement 'If your state cares about climate change, you need to take the reins and step up and direct your transportation funds to projects that are going to reduce emissions,' Frommer said. 'We may not be able to rely on the federal government to put that policy in place or to really help you in many ways.' Colorado's approach moves east Minnesota followed Colorado's lead and adopted a similar rule to offset greenhouse emissions. Other states that are part of the network are pushing proposals this session. The Maryland House recently passed its version of the Colorado law, and Senate sponsor Shelly Hettleman said she's cautiously optimistic it will win final passage before lawmakers adjourn. In trying to persuade her colleagues, Hettleman has focused less on the environmental benefits than what she sees as economic ones. A study commissioned by the Colorado transportation department projected up to $40 billion in savings through improved air quality, road safety and reduced traffic congestion, among other things. Lawmakers in the Clean Rides states of Illinois and Massachusetts have advanced similar proposals, but they've encountered resistance from some business leaders and advocates for road construction. 'This is another ill-advised piece of legislation, not based upon science, that will defer needed improvements to our crumbling transportation infrastructure in Illinois,' said Mike Sturino, president and CEO of the Illinois Road and Transportation Builders Association. 'Commuters will have to wait for improvements to our existing interstate system, as this bill would delay addressing unsafe conditions on our roads and bridges.' Is there any interest from red states? Although most of the state leaders who have pushed alternative transportation options have been Democrats, the Clean Rides Network said more conservative states have shown interest in some of the topics, too. Advertisement Just as Colorado's anticipated cost savings helped spur legislation in Maryland, economic concerns continue to be foremost in the minds of residents, with some studies showing that transportation ranks second to housing in consumer costs. 'Forget about the cost of eggs. It's never been more expensive to drive a car,' said Miguel Moravec with the nonprofit climate think tank RMI, which created a calculator to help states project the money they could save through policies that reduce emissions. Virginia employs a scale that scores potential transportation projects based on factors such as safety, congestion relief, and environmental impacts. Utah launched an ambitious transit plan for the rapidly growing state, while Montana implemented land use and zoning reforms that made cities more walkable. Muhammed Patel, senior transportation advocate for the Natural Resources Defense Council in Chicago, said states are at least rethinking some of their policy priorities. 'We do live luckily in a country where states have authority over their own transportation systems,' Patel said. 'There's flexibility innately built in.'
CBS News
06-03-2025
- CBS News
Denver Travel & Adventure Show is a window to the world
Start planning your next vacation at Denver's Travel & Adventure Show at the Colorado Convention Center. The two-day exhibition features hundreds of booths featuring domestica and international destinations. Get a feel for the culture and inside knowledge for your favorite locales so you can travel like a local. Exhibitors include organizations from Africa, Asia, North America, South America, Europe and the Middle East. You can learn about cruise options, sporting excursions, and travel products. "What I love about it is it's the world in microcosm. Yougo to the Travel & Adventure Show, and there are dozens of booths with people from all over the planet wanting to tell you about their home, how to see it best, they give show only discounts, and there are real travel experts there giving advice," said Pauline Frommer, Editorial Director of Frommer's Travel Guides. The show includes three theaters with various speakers schedule throughout the two-day event. In the Travel Theater, you can hear from the travelers you've seen on TV or follow in Instagram, including Chris Burkard, Peter Greenberg, and Frommer. "I'll be talking about the new trends in travel. One of the most invidious ones is what I'm calling surveillance pricing. Thanks to AI, they have much more information as to who you are as the consumer, and in travel that could mean different prices being surfaced to you when you do a search. We're recommending virtual private networks or VPN's for travel searches. That's just one of the tips and tricks I'll give you," Frommer explained. Frommer's family is known for publishing the Frommer's Travel Guides. She's spent her entire life traveling the world, and shares the lessons she's learned along the way. "For meaningful, you want to meet people. There are organizations called Greeters in 60 countries, 400 cities around the world. These are locals who love their local community, and they give free tours, so you might be taken to the local school, or see whta a church is like, or learn about history by a local who's been impacted by it. It's a wonderful way to travel," Frommer said. In the Destination Theater, you can hear about specific places and get the inside scoop on where to go, what to do, and how to get there. Speakers in that theater include the Grand Lake Camber of Commerce, Explore Fairbanks, Viking Cruises, and David McGuffin's Exploring Europe. In the Savy Traveler Theater, you can learn how to go on your next adventure without breaking the bank. Speakers include Russell Hannon talking about cutting travel costs, Jennifer Broome outlining how to get the most out of a trip to a national park, and Scott Mayerowitz with frequent flyer hacks. "Do you have a favorite spot?" CBS News Colorado Mornings anchor Brian Flores asked. "I loved Vietnam," Frommer replied. "Really moving to go there. Incredibly friendly people. Very interested in what Americans think of them." The Denver Travel & Adventure Show runs March 8 & 9, 2025 at the Colorado Convention Center.
