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Medical researcher up for award
Medical researcher up for award

Otago Daily Times

time5 days ago

  • Health
  • Otago Daily Times

Medical researcher up for award

The researcher behind a slow-release ketamine tablet, developed to treat people with treatment-resistant depression, has been named a finalist in the 2025 KiwiNet Research Commercialisation Awards. University of Otago Hazel Buckland chair in psychological medicine Prof Paul Glue is up for the BNZ Researcher Entrepreneur Award for his pioneering research. The awards honour those who bridge the gap between research and business, transforming scientific discoveries into real-world solutions that create lasting benefit for New Zealanders. "I'm absolutely blown away by this," Prof Glue said. "Since this project started, it's taken on a whole new life of its own." For nearly a decade, he has been working on the medication, which is now about to undergo Food and Drug Administration approval, with the aim of getting it on the market within the next three years. He said the new medication was working well for patients and almost everyone who took it during trials decided they wanted to stay on it. While he was delighted to be named a finalist in the awards, Prof Glue said the biggest reward was that it was changing people's lives. "The contrast between what their pattern of illness was like before, versus being on this drug and basically being well, has been striking — life-changing for them." Most people who have treatment-resistant depression are destined to be stuck at home, unable to work, continually dealing with relationship problems — a place far from a normal life, he said. "The stats show that about one in five women, and one in 10 men in New Zealand will have an episode of depression, and about a third of the patients won't respond to conventional treatments. "They're functionally impaired. It's a big population, and at the moment, we as a health system do not have an effective line of treatment for this big population." Doctors usually used the anaesthetic drug as an effective means of sedation and pain relief, but ketamine was also given to patients with treatment-resistant depression, via injection or nasal spray. Unfortunately, it had major side effects in this form, he said. "It can make patients feel very spaced out, very sleepy. They can't walk for about half an hour. "That's why you have to have it in a clinic. "It's quite a burden on resources for patients and the health system." However, Prof Glue's slow-release ketamine tablets were absorbed by the body over about 10 hours and had few side effects. Because of that, it reduced the risk of abuse by drug users. It meant the tablets could be picked up from a pharmacy on prescription, potentially making treatment a much cheaper and more convenient option, compared with weekly clinic visits for ketamine injections or nasal sprays, he said. KiwiNet chief executive Dr James Hutchinson said the finalists represented the "cutting edge of innovation", turning world-class science into high-value, high-growth ventures with real impact for New Zealand. "From pioneering medical treatments to clean tech, sustainable food production and space innovation, they show how science can tackle real-world challenges — growing our economy, boosting productivity, and doing good in our communities." The winners of the KiwiNet Awards will be announced at a ceremony in Auckland on October 22.

Too Much – Season 1 Episode 10 Recap, Review & Ending Explained
Too Much – Season 1 Episode 10 Recap, Review & Ending Explained

The Review Geek

time10-07-2025

  • Entertainment
  • The Review Geek

Too Much – Season 1 Episode 10 Recap, Review & Ending Explained

The Idea Of Glue Too Much has been quite the ride over these 10 episodes, taking us from the bad to the worse, to the insufferable and back again. However, episode 5 does dive into exactly what happened in Jess' past, which is important for context in this finale. What happened between Jess and Zev? Back in Brooklyn, Jessica was abandoned by her friends who left a bar and moved on without her. However, she's more hung up over the pizza that the waiter takes away. This gets her talking to Zev, and the pair hit it off. Much lie with Felix, the pair kiss on the first night and have sex too. The pair do eventually move in together, but he doesn't want the place to be completely pink. Jess though, has a hard time compromising. Zev eventually calls out Jess for her insecurities and attention-seeking, not wanting to be a power couple. He just wants her to be happy for them to be together. He doesn't think Jess is willing to put the work in, and the turning point comes from her bringing a dog in and refusing to train it. Eventually Zev forces her to let the dog go given her lack of training. This is when Zev meets with Wendy and the pair hit it off immediately. Jess is jealous and knows the pair aren't connecting anymore, which is the beginning of the end. Jess cheats on Zev with a random guy and she ends up pregnant. It's not clear whether the baby is this random guy's or Zev's but that night, she guilt-trips him into thinking the child is his. She doesn't tell him about her cheating and decides an abortion is the right way forward. He agrees. What happens to Astrid? Episode 10 then begins with things tense at work. Boss is not happy that one of his old videos from his straight chavvy days has surfaced. It's here we learn that his real name is Gary and the group laugh about it, which worse to break the ice a bit. The real tension here though stems from Jess and Felix breaking up. It's almost as if getting in a relationship with someone you've just met after two days isn't a good idea. Go figure! While Felix is packing his stuff, he notices that Astrid is having trouble breathing, and he rushes her to the vet. Unfortunately, he's too late and when Jess shows, she's beside herself with grief. How does Jessica get a new perspective? Jess lashes out at Felix, calling him selfish and blaming him for what's happened. He owns up that he's not a nice person but has always been honest with her about this. He calls her out for issues she has too, including how hung up on her ex she is, but Jessica refuses to take accountability. She won't own up to her mistakes and the pair eventually part ways. Jess receives a message from Wendy though, asking to meet. She wants Jessica's help. She admits that when she and Zev first started dating, he mentioned how they'd been split up for six months. He is truthful about how she wanted to split with him but the timings seem to be off here. Wendy brings up how Zev is horrible and also messed her around too. Jessica admits she doesn't want to cling to the past anymore and is ready for a fresh start. It gives her a new perspective, shakes free some of the baggage she had and decides to go and chase down Felix and win him back. How does Too Much end? On the way, Gaz confesses his love for her but Jess lets him down gently. They do eventually track down Felix while he's doing a protest on the road. The pair confess their love to one another and while police show to arrest them, Felix decides they should get married. We then cut forward to Felix and Jessica's wedding, where everybody is joined together to celebrate their marriage. She's also wearing her old shirt that Wendy has dropped off, as the pair have obviously patched up their differences. The Episode Review So in the end Too Much lives up to its name, as it's way too much in both story and dialogue. The comedy feels overdrawn and has this try-hard energy to it that fails to resonate. The entire thing feels painfully dated and unfunny, like someone took the Ghostbusters 2016 script and decided to make it even less funny. It also doesn't help that Jess doesn't really learn anything across the entirety of this show. It turns out she's not an asshole for lying to Zev and guilt-tripping him into aborting a baby – a very likely result of a one-night-stand where she got pregnant. This alone is a shocking lack of accountability on Jessica's behalf but then Wendy shows up and affirms everything she's saying by agreeing that Zev is awful, so it's okay. In the end, Jessica doesn't have to say anything and Jessica never faces her own insecurities or why this relationship didn't work out. It feels like a self-insert from creator Lena Dunham, and not in a good way. This is only made worse by the fact that for some reason every straight guy in this show is just in love with Jess. From Gaz confessing his love to Jameson and Felix etc. Of course, we do get our little 'happily ever after' at the end with Felix and Jess but it comes at the expense of poor comedy and a terrible character arc. Lets hope season2 doesn't get green-lit for all our sakes.

Irvine Welsh to make appearance at Glasgow record store
Irvine Welsh to make appearance at Glasgow record store

Glasgow Times

time03-07-2025

  • Entertainment
  • Glasgow Times

Irvine Welsh to make appearance at Glasgow record store

The Trainspotting creator will be promoting his new album and book at Assai Records in Sauchiehall Street on July 25. Fans of the writer who also penned Filth, Glue and the Acid House, among many more, will get the chance to interact with the author in a Q&A session. READ NEXT:Outcome of inspections at 8 of Glasgow's homeless hotels revealed More famous for his groundbreaking books, the Edinburgh-born author has turned his hand to music with a new album Men in Love together with the Sci-Fi Soul Orchestra. It is described as: 'A collaborative concept album, exploring the complexities of love, relationships, and the human condition. 'The album blends classic Motown and disco influences with contemporary electronic dance production, creating a unique and powerful sound that is both nostalgic and fresh.' Released at the same time will be Welsh's new novel, also titled Men in Love, which is a sequel to Trainspotting and features the same characters made famous in the 90s by the book and then film. READ NEXT: Opinions wanted on plans to redesign busy Glasgow city centre street It follows Renton, Sick Boy, Spud and Begbie, some of the most memorable characters created in Scottish literature. Assai Records, which regularly hosts in-store events with artists, promoted the event and signing on its website. It states: 'We are delighted to welcome Irvine Welsh for an instore Q&A followed by signing in support of his new album and book Men In Love (released 25th July 2025) at Assai Records Glasgow, on Friday 25th July 2025, at 5pm.'

Dua Lipa And Callum Turner Made Their Red Carpet Debut At The Met Gala
Dua Lipa And Callum Turner Made Their Red Carpet Debut At The Met Gala

Buzz Feed

time05-05-2025

  • Entertainment
  • Buzz Feed

Dua Lipa And Callum Turner Made Their Red Carpet Debut At The Met Gala

After a little over a year together, Dua Lipa and Callum Turner finally made their red carpet debut at the 2025 Met Gala. The singer and her rumored fiancé shared plenty of sweet looks in front of the cameras. Dua looked stunning in Chanel. In case you didn't know, Callum is an actor who's known for Glue, Queen and Country, and Fantastic Beasts: The Crimes of Grindelwald. Their relationship first went public in January 2024. They reportedly got engaged in December 2024.

The Life of Sean DeLear review – loving film about queer black punk rocker, and secret legend
The Life of Sean DeLear review – loving film about queer black punk rocker, and secret legend

The Guardian

time29-04-2025

  • Entertainment
  • The Guardian

The Life of Sean DeLear review – loving film about queer black punk rocker, and secret legend

That's Sean DeLear, pronounced like 'chandelier', born Anthony Robertson in 1964. You probably haven't heard of him: DeLear was the lead singer of a band called Glue on the underground post-punk scene in Los Angeles in the 1980s and 90s. On stage, he performed in drag, singing punk songs dressed like a 1960s go-do dancer in cute little dresses. The band never landed a major record deal, and DeLear died from cancer in 2017. This sweet, scrappy documentary has been lovingly put together by his friend Markus Zizenbacher. It's not the first posthumous attempt at recognition for DeLear. In 2023, his teenage diary, written in 1979, was published under the title I Could Not Believe It. Extracts of this queer black memoir are read here on the voiceover – and they are glorious. Even aged 14 years old, living with his Christian parents in a conservative suburb of Los Angeles, DeLear was proudly, joyfully gay, though this was before the terror of Aids. The interviews in the film with his mum and brother, an evangelical pastor, feel a little bit thin; his family accepted his sexuality, they say, but not much else. DeLear never had a proper job. For years he believed his band Glue would make it. A friend says the reason they didn't might have something to do with having a black man in drag as lead singer, and tells the story of a Glue video being pulled from MTV by an executive. DeLear later moved to Vienna, joining a performance art collective, and lived like a celebrity, never thinking about where the rent was coming from. And celebrities loved him: when he walked into the women's toilets at Kate Moss's 21st birthday party, a gaggle of supermodels swarmed him, cooing over his dress. Does it matter that he wasn't famous himself? Clearly he was a legend to everyone who knew him. The Life of Sean DeLear is on True Story from 2 May.

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