Latest news with #Handley
Business Wire
2 days ago
- Business
- Business Wire
Tivic Health Advances Discussions on Use of Entolimod as a Radiation Countermeasure at Military Health System Research Symposium 2025
FREMONT, Calif.--(BUSINESS WIRE)--Tivic Health® Systems, Inc. (Nasdaq: TIVC), a diversified therapeutics company, is proud to announce it advanced discussions with key US Government agencies through its participation in the 2025 Military Health System Research Symposium (MHSRS), held August 4-7, 2025, in Kissimmee, Florida. The MHSRS is the Department of Defense's premier scientific meeting that brings together military, academic, and industry experts to discuss medical research and innovation in support of warfighter health and readiness. Direct Access to DoD Decision-Makers and Researchers MHSRS provides direct access to organizations seeking military partnerships and connects companies with key funding organizations. Tivic's President of Biopharma and Chief Operating Officer, Michael Handley, met with key members of the Biomedical Advanced Research and Development Authority (BARDA), the Armed Forces Radiobiology Research Institute (AFRRI) and the Medical CBRN Defense Consortium (MCDC) to discuss potential pathways to deploy Entolimod as a military countermeasure. BARDA's mission is to develop medical countermeasures that address the public health and medical consequences of chemical, biological, radiological, and nuclear (CBRN) accidents, incidents and attacks, pandemic influenza, and emerging infectious diseases. AFRRI's mission is to defend the Nation from nuclear and radiological threats through research, leadership, training, and education. The MCDC was formed in response to the US Government's expressed interest to engage and fund advanced development efforts to support the Department of Defense's (DoD) medical pharmaceutical and diagnostic requirements as related to enhancing the mission effectiveness of military personnel. 'It was an honor to contribute to the vital conversations that were focused generally on radiation medical countermeasures, and specifically on our lead clinical product candidate, Entolimod, which has the potential to protect the warfighter in the instance that they are exposed to radiation,' said Handley. Representatives from Tivic joined global thought leaders, military leaders and researchers to share insights, explore collaborative opportunities, and present ongoing research intended to improve health outcomes for warfighters exposed to radiation in the field. About MHSRS MHSRS serves as a dynamic platform for the exchange of research findings across multiple disciplines, including combat casualty care, medical countermeasures, infectious disease, and mental health. The symposium fosters collaboration among business leaders, scientists, clinicians, and policymakers, ensuring innovations reach those who serve as quickly and effectively as possible. About Tivic Tivic's dual platform utilizes the body's biopharmaceutical and bioelectronic systems to treat unmet medical needs through targeting the immune system. Tivic's biologics compounds activate an innate immune pathway to prevent cell death in the bone marrow and epithelial tissues across systems impacted by radiation and age. The company's lead drug candidate, Entolimod™ for acute radiation syndrome, is a novel TLR5 agonist that has been granted Fast Track designation and is in late stage development. Tivic's bioelectronic program is developing a novel, non-invasive medical device designed to target the neural pathways implicated in many prevalent and debilitating diseases. Early trials show promising signals that Tivic's approach may regulate specific biologic responses, and the company believes its early-stage vagus nerve stimulation device has the potential to deliver clinical outcomes similar to or better than those of surgically implanted devices. To learn more about Tivic, visit: Forward-Looking Statements This press release may contain 'forward-looking statements' that are subject to substantial risks and uncertainties. All statements, other than statements of historical fact, contained in this press release are forward-looking statements. Forward-looking statements contained in this press release may be identified by the use of words such as 'anticipate,' 'believe,' 'contemplate,' 'could,' 'estimate,' 'expect,' 'intend,' 'seek,' 'may,' 'might,' 'plan,' 'potential,' 'predict,' 'project,' 'target,' 'aim,' 'should,' 'will' 'would,' or the negative of these words or other similar expressions, although not all forward-looking statements contain these words. Forward-looking statements are based on Tivic Health Systems Inc.'s current expectations and are subject to inherent uncertainties, risks, and assumptions that are difficult to predict. Further, certain forward-looking statements are based on assumptions as to future events that may not prove to be accurate, including as a result of interactions with and guidance from the FDA and other regulatory authorities, as well as interactions with governmental agencies, such as BARDA, the AFRRI and the MCDC; changes to the company's relationship with the its partners; the failure to obtain FDA or similar clearances or approvals and noncompliance with FDA or similar regulations; the company's future development of its ncVNS treatment, Entolimod and Entolasta; changes to the company's business strategy; timing and success of clinical trials and study results; regulatory requirements and pathways for approval; consummation of any strategic transactions; the company's need for, and ability to secure when needed, additional working capital; the company's ability to maintain its Nasdaq listing; and changes in tariffs, inflation, legal, regulatory, political and economic risks. Actual results could differ materially from those contained in any forward-looking statement as a result of various factors. Accordingly, you are cautioned not to place undue reliance on such forward-looking statements. For a discussion of risks and uncertainties relevant to the company, and other important factors, see Tivic Health's filings with the SEC, including, its Annual Report on Form 10-K for the year ended December 31, 2024, filed with the SEC on March 21, 2025, under the heading 'Risk Factors," as well as the company's subsequent filings with the SEC. Forward-looking statements contained in this press release are made as of this date, and Tivic Health Systems, Inc. undertakes no duty to update such information except as required by applicable law.
Winnipeg Free Press
23-06-2025
- Sport
- Winnipeg Free Press
Orioles place catcher Maverick Handley on concussion injured list a day after collision at plate
BALTIMORE (AP) — The Baltimore Orioles placed catcher Maverick Handley on the seven-day concussion injured list a day after he was knocked over in a collision at the plate. The Orioles announced the move Monday ahead of their game against the Texas Rangers. Baltimore also selected the contract of catcher Chadwick Tromp from Triple-A Norfolk and transferred infielder Ryan Mountcastle to the 60-day injured list because of a strained right hamstring. Handley was hurt in the second inning Sunday against the New York Yankees when Jazz Chisholm Jr. tried to score on DJ LeMahieu's single to left. Outfielder Colton Cowser's throw was up the third-base line and Handley moved over to field the ball. He reached for the ball just as Chisholm ran past him. Chisholm attempted to veer inside, but couldn't avoid the collision and Handley was spun by the contact. The 27-year-old Handley left the game after a discussion with interim manager Tony Mansolino and head athletic trainer Scott Barringer. Baltimore replaced Handley with former Yankees player Gary Sánchez. Handley made his major league debut on April 29. The Orioles remain without All-Star catcher Adley Rutschman, who strained his left oblique and is on the injured list for the first time in his major league career. Winnipeg Jets Game Days On Winnipeg Jets game days, hockey writers Mike McIntyre and Ken Wiebe send news, notes and quotes from the morning skate, as well as injury updates and lineup decisions. Arrives a few hours prior to puck drop. ___ AP baseball:
San Francisco Chronicle
23-06-2025
- Sport
- San Francisco Chronicle
Orioles place catcher Maverick Handley on concussion injured list a day after collision at plate
BALTIMORE (AP) — The Baltimore Orioles placed catcher Maverick Handley on the seven-day concussion injured list a day after he was knocked over in a collision at the plate. The Orioles announced the move Monday ahead of their game against the Texas Rangers. Baltimore also selected the contract of catcher Chadwick Tromp from Triple-A Norfolk and transferred infielder Ryan Mountcastle to the 60-day injured list because of a strained right hamstring. Handley was hurt in the second inning Sunday against the New York Yankees when Jazz Chisholm Jr. tried to score on DJ LeMahieu's single to left. Outfielder Colton Cowser's throw was up the third-base line and Handley moved over to field the ball. He reached for the ball just as Chisholm ran past him. Chisholm attempted to veer inside, but couldn't avoid the collision and Handley was spun by the contact. The 27-year-old Handley left the game after a discussion with interim manager Tony Mansolino and head athletic trainer Scott Barringer. Baltimore replaced Handley with former Yankees player Gary Sánchez. Handley made his major league debut on April 29. The Orioles remain without All-Star catcher Adley Rutschman, who strained his left oblique and is on the injured list for the first time in his major league career.
Fox Sports
23-06-2025
- Sport
- Fox Sports
Orioles place catcher Maverick Handley on concussion injured list a day after collision at plate
Associated Press BALTIMORE (AP) — The Baltimore Orioles placed catcher Maverick Handley on the seven-day concussion injured list a day after he was knocked over in a collision at the plate. The Orioles announced the move Monday ahead of their game against the Texas Rangers. Baltimore also selected the contract of catcher Chadwick Tromp from Triple-A Norfolk and transferred infielder Ryan Mountcastle to the 60-day injured list because of a strained right hamstring. Handley was hurt in the second inning Sunday against the New York Yankees when Jazz Chisholm Jr. tried to score on DJ LeMahieu's single to left. Outfielder Colton Cowser's throw was up the third-base line and Handley moved over to field the ball. He reached for the ball just as Chisholm ran past him. Chisholm attempted to veer inside, but couldn't avoid the collision and Handley was spun by the contact. The 27-year-old Handley left the game after a discussion with interim manager Tony Mansolino and head athletic trainer Scott Barringer. Baltimore replaced Handley with former Yankees player Gary Sanchez. Handley made his major league debut on April 29. The Orioles remain without All-Star catcher Adley Rutschman, who strained his left oblique and is on the injured list for the first time in his major league career. ___ AP baseball: recommended
NBC Sports
22-06-2025
- Sport
- NBC Sports
Orioles catcher Maverick Handley leaves game after collision with Yankees' Jazz Chisholm Jr.
NEW YORK — Baltimore Orioles backup catcher Maverick Handley left Sunday's 4-2 loss to the New York Yankees after being knocked over in a collision at the plate with Jazz Chisholm Jr. 'He got hit pretty hard,' Orioles manager Tony Mansolino was quoted as saying by the Mid-Atlantic Sports Network. 'We haven't seen a collision like that at the plate, probably, since all the new rules came in. So we're evaluating him right now, full body, every part of it. We'll have more information tomorrow. ... We're evaluating everything right now, so nothing official on concussion protocol. There's obviously a chance that that happens. We'll have more information tomorrow on him.' With Baltimore ahead 2-0 in the second, Chisholm hit a two-out double off Dean Kremer and went home on DJ LeMahieu's single to left. Colton Cowser's throw was up the third-base line. Handley moved to his left for the throw, arriving for the ball at the same time as Chisholm, who tried to veer to the inside to avoid contact. Chisholm, whose left cleat had come off as he speeded down the line, caught Handley with his right arm, fell past the plate and had to come back to touch it. Handley, a 27-year-old who debuted in April, got up slowly and was removed after a discussion with Masolino and head athletic trainer Scott Barringer. Baltimore replaced Handley with former Yankees player Gary Sánchez. Baltimore already is without All-Star catcher Adley Rutschman, who strained his left oblique and is on the injured list for the first time in his major league career. After San Francisco All-Star catcher Buster Posey sustained a season-ending leg injury in May 2011, Major League Baseball ahead of the 2014 season adopted a rule preventing catchers from blocking a runner's direct path to the plate without the ball.
