Latest news with #Hodgkin
Time of India
3 days ago
- Business
- Time of India
Zydus Life's plans for cancer biosimilar hit a legal hurdle
Tired of too many ads? Remove Ads Tired of too many ads? Remove Ads Mumbai: The Delhi High Court has issued an interim injunction against Ahmedabad-based drug maker Zydus Lifesciences after a case filed by the US pharma giant Bristol Myers Squibb alleging patent infringement on its blockbuster anticancer drug Opdyta nivolumab ) branded as Opdivo in other restraining order comes as a setback for the Indian drug maker which was running clinical trials in India for the launch of the biosimilar versions of nivolumab. The earliest patent for the drug expires in India on May 2, 2026. The next hearing for the case is August 101-page order issued on July 18 by Justice Mini Pushkarna ruled that the defendants, and all others acting on its behalf, are restrained from manufacturing, using, selling, offering for sale, importing, exporting, advertising, or dealing in any biosimilar/similar biologic of nivolumab, the suit patent, during the pendency of the present suit. The order stated the plaintiffs shall suffer irreparable loss, in case the interim relief as prayed for, was not injections are one of the many latest generation immunotherapy drugs also known as checkpoint inhibitors increasingly used to treat several types of cancers including skin, lungs, kidneys, and Hodgkin lymphoma. It works by activating the body's T-cells or immune cells by targeting a protein called PD-1, thereby unleashing an attack on the cancer vials are sold in India for roughly '2 lakh but for patients who are part of the company's assistance or access programs, the drug is available at a slab-wise discounted the India data is not available, globally Bristol Myers Squibb recorded Opdivo sales of $9.3 billion in 2024. Indian companies have launched biosimilars at half the cost of those charged by their global in Indian patent laws told ET that the court has taken a view that stockpiling of a product during its active patent life amounts to infringement and to release it or flood the market is not legally valid."This opinion may have implications for the other ongoing disputes like the weight-loss drug semaglutide (branded Wegovy) case between Novo Nordisk and Dr. Reddy's Labs or Roche versus Natco for Risdiplam (drug used for a rare disease called spinal muscular atrophy or SMA) case," a senior lawyer petition from BMS noted that Zydus Lifesciences was conducting clinical trials for nivolumab and on its investigation found that the company had plans to launch it during the patent period. The Indian company, it said, had applied for a marketing approval with the central drug regulatory its part, lawyers on behalf of Zydus defended saying its product ZRC-3276 does not infringe upon the existing patents and is following the regulatory was represented by a battery of top lawyers including Harish Salve, Dushyant Dave, and Rajiv Nayar, while Squibb & Sons was represented by Sandeep Sethi, PS Raman, Amit Sibal and Pravin Anand, among others.
Daily Mirror
11-07-2025
- Health
- Daily Mirror
'Doctors thought my rash was eczema - then I was told I had six months to live'
When Rachel Evans developed a rash that made her feel as though she had 'insects crawling all over her body', doctors reassured her it was just eczema. Then she received a devastating diagnosis After developing an "intense" rash across her body, Rachel Evans was told by doctors that she had eczema, but she couldn't shake the feeling that something far more serious was going on. The 46-year-old was plagued by extreme itching, dizzy spells, nosebleeds, debilitating fatigue and unexplained weight loss, and despite pushing for answers, she was repeatedly turned away. Rachel recalled: "I couldn't manage my symptoms at all. The rash was unmanageable; it felt like there were insects crawling all over my body. I couldn't cope with the intense itchiness of that rash. I couldn't sleep, and I couldn't work. It completely took over my day and night, and the fatigue I felt was intense." Her symptoms started in 2020, but it took nearly two years for doctors to send Rachel for a chest X-ray, which detected a shadow on her lungs. A CT scan and biopsy followed, and, to her horror, Rachel was diagnosed with Stage 4 Hodgkin lymphoma. Without treatment, doctors warned she may only have six months to live. READ MORE: 'I was told I had heatstroke from Turkey holiday - reality was scary' Married mum Rachel was devastated by the news, and says this was made even more difficult on account of her struggles with undiagnosed ADHD. Rachel, of Almondsbury, South Gloucestershire, shared: "Before my diagnosis, I was so burnt-out from struggling with life and undiagnosed ADHD. I have two words for how I was feeling: survival mode. "My doctors thought I would only have six months to live if I didn't have treatment. As I was emotionally dysregulated, I considered allowing my body to die from the cancer naturally. "But then I was able to consider the needs of my son, and so I decided to take the six months of ABVD chemotherapy." She added: "Everything happened really quickly. It was a very traumatic experience, more trauma on top of lifelong physical and emotional trauma caused by the ADHD. This developed into complex post-traumatic distress after chemotherapy." According to Rachel, who has a 10-year-old son and a nearly 20-year-old stepdaughter, her cancer treatment had a profound impact on her and her family. This was further compounded by the sudden illness and death of her mother-in-law. Her husband went to be with his mother in her final days, and then spent time grieving with his father and sister. Meanwhile, Rachel was left to care for her son alone for several weeks, amid a myriad of escalating challenges. Rachel explained: "Our home life was already emotionally challenged due to my undiagnosed ADHD, and our son's undiagnosed ASD and ADHD, so the cancer treatment caused a massive nosedive in the atmosphere. "In addition to the physical and emotional suffering from chemotherapy, like the pain of the picc line going in, problems with them extracting blood, panic attacks before chemo sessions, excruciatingly painful haemorrhoids, bloating, tummy pain, weight gain, loss of taste, nausea and receding gums, we had to deal with the very sudden family bereavement." In March 2023, Rachel went into remission, and while she still struggles with climbing stairs or hills, she's thankfully feeling much stronger physically. However, emotional recovery has proven to be more complicated. Rachel revealed: "My mental health has taken three years to recover. Thanks to ADHD medication, HRT for perimenopausal symptoms, psychotherapy, self-educating, and finding therapy myself, I am fully ready to engage with the world again, not just restored, but transformed." Going forward, Rachel hopes her story will help raise awareness of the more "sneaky" symptoms of Hodgkin lymphoma. She said, "I wish that more health care professionals knew more about the symptoms - blood cancer is sneaky, and it hides in the shadows. "I had a movable, painless lymph node, but not in my neck like most people get, it was in my jaw. This is uncommon, but not unknown. "My weight loss was subtle because I was already quite slender, and the weight had dropped off gradually throughout the years. "I had a history of eczema, and a history of depression and anxiety, and I think this history masked the root causes of the blood cancer and the ADHD." Rachel says her ADHD only added to the significant challenges of her diagnosis and subsequent recovery. She continued: "I don't want any other human being to struggle the way I did, either physically, emotionally, or both. "I especially have a heart for women who have undiagnosed or diagnosed ADHD, and are perimenopausal, and have had to face a cancer diagnosis on top. ADHD is subtle and not easily detected, especially in women, unless you do the detective work. "I want to raise awareness so that others are educated and have a better chance of enjoying life, in all its fullness. I believe my life was saved in many ways, for many reasons, and sharing my story is just one of them."
Irish Independent
28-06-2025
- Entertainment
- Irish Independent
'He got bored of work, and made some bad choices' – Jared Harris on his father Richard's legacy
Actor Richard Harris's archive of career memorabilia and personal items will go on show for the first time in his hometown of Limerick next month. Here, his son talks about his father's career highs and lows, his relationship with his children, and with alcohol, and why he played the fame game When the Limerick-born actor Richard Harris was in hospital being treated for advanced Hodgkin's lymphoma in 2002, he began writing his autobiography. It probably goes without saying that it would have made a hell of a read, for he was a man who had lived several lives, each one more colourful than the last. 'Unfortunately, there was some notepad [that he was writing in] that was wrapped up in all these newspapers, and one of the nurses came in and chucked the newspapers away,' Jared Harris, Richard's son, recalls. 'He was going to start again though, but… yeah. I think he definitely had an appetite for more [living].'
Irish Independent
28-06-2025
- Entertainment
- Irish Independent
‘'Hellraiser' was a story he himself fed to the press' – Jared Harris on his father Richard's legacy
Actor Richard Harris's archive of career memorabilia and personal items will go on show for the first time in his hometown of Limerick next month. Here, his son talks about his father's career highs and lows, his relationship with his children, and with alcohol, and why he played the fame game When the Limerick-born actor Richard Harris was in hospital being treated for advanced Hodgkin's lymphoma in 2002, he began writing his autobiography. It probably goes without saying that it would have made a hell of a read, for he was a man who had lived several lives, each one more colourful than the last. 'Unfortunately, there was some notepad [that he was writing in] that was wrapped up in all these newspapers, and one of the nurses came in and chucked the newspapers away,' Jared Harris, Richard's son, recalls. 'He was going to start again though, but… yeah. I think he definitely had an appetite for more [living].'
The Hindu
25-06-2025
- Health
- The Hindu
Apollo Cancer Centres launches ‘CanWin' to support patients, survivors, and caregivers
Apollo Cancer Centres (ACC) has launched CanWin, a cancer support group designed to provide structured emotional and psychological support to patients, survivors, caregivers and healthcare professionals. Unveiled during National Cancer Survivors Month, the initiative aims to complement clinical treatment with survivor-led guidance, therapy-based storytelling and open dialogue. The launch event began with survivors sharing their personal narratives of treatment, recovery and coping. A 10-year-old Medulloblastoma survivor from Chennai shared his experience, starting with how a routine check-up led to answers for many of his symptoms. A Hodgkin lymphoma survivor spoke about her delayed diagnosis and complex treatment journey. 'Just months after giving birth, I discovered a lump — first mistaken for tuberculosis. What followed were relapses, five lines of chemotherapy, a bone marrow transplant and 35 rounds of radiation. I missed my child's early years, but I came through with the support of my family and medical team,' she said. Priyanka Bagdi, a leukemia survivor, doctor and author of a book about her experience, spoke about her prolonged hospital stays and the emotional toll of treatment. Experts at the event stressed that while clinical outcomes are improving with advanced diagnostics and early detection, stigma around cancer screening and diagnosis remains a significant barrier. In a panel discussion that followed they called for urgent efforts to normalise conversations around diagnostic tools and to strengthen psychosocial support within cancer care. The programme will continue through monthly support group meetings, survivor-led workshops, expert sessions and volunteering opportunities.
