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Beware of common & silent non-alcoholic liver disease
Beware of common & silent non-alcoholic liver disease

Time of India

time3 days ago

  • Health
  • Time of India

Beware of common & silent non-alcoholic liver disease

Bhopal: Non-alcoholic fatty liver disease can be a silent disease that shows few or no symptoms but can escalate to serious liver damage. It is a common ailment as well, one that you should be beware of. A state-wide initiative for non-alcoholic fatty liver disease screening began from June 1, including in Bhopal, targeting citizens aged above 30 years. According to a press release, this initiative focuses on awareness, early detection, treatment and prevention of liver-related ailments. The govt of Madhya Pradesh has established a partnership with the Institute of Liver and Biliary Sciences, New Delhi through an MoU. Earlier on May 21, the governor and the chief minister officially inaugurated this campaign on May 21. The programme involves initial screening by Asha workers for suspected NAFLD cases. They will collect data on BMI exceeding 23, waist circumference surpassing 80 cm in women and 90 cm in men, and diabetes history. Suspected cases will be reported to community health officers and workers. Participants will receive guidance on consuming home-available nutritious food and avoiding alcohol and tobacco, with regular follow-ups. by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Encontre voos low-cost Voos | Anúncios de Pesquisa Saiba Mais Undo Medical professionals will conduct platelet count, SGOT (AST), SGPT (ALT) tests based on FIB-4 score calculations, followed by FIBROSCAN when medically indicated. Chief medical and health officer (CMHO) Bhopal, Dr Prabhakar Tiwari, emphasised that regular check-ups for non-communicable diseases can reduce illness severity. The non-communicable disease control programme and viral hepatitis control programme offer free services for liver-related issues. Previously, the Nirogi Kaya Abhiyan campaign screened for various non-communicable diseases, including high blood pressure, diabetes, cancer and non-alcoholic fatty liver disease, reaching over 50,000 people. Field health workers received training about liver function, related issues, symptom identification, dietary advice, exercise recommendations, lifestyle guidance and BMI calculations. The liver performs crucial functions continuously, including blood purification, toxin removal, nutrient storage, energy regulation, blood clotting maintenance, and production of bile, proteins, vitamins and minerals. Common liver conditions include fatty liver, fibrosis, hepatitis, cirrhosis and liver cancer.

Selfless Love: Mother donates organ to son for second time
Selfless Love: Mother donates organ to son for second time

India Gazette

time27-05-2025

  • Health
  • India Gazette

Selfless Love: Mother donates organ to son for second time

New Delhi [India], May 27 (ANI): In an extraordinary act of maternal love, a 60-year-old mother has given her son the gift of life for the second time at the Institute of Liver and Biliary Sciences (ILBS), New Delhi. The remarkable story began in 2015 when she donated a portion of her liver to her son, born in 1997, who was diagnosed with a life-threatening liver ailment. Nearly a decade later, her son developed kidney failure, and she selflessly offered to donate one of her kidneys. She was declared fit even after her earlier liver donation, and was cleared to donate one of her kidneys. The renal transplant team at the Institute of Liver and Biliary Sciences (ILBS) in New Delhi, led by Dr Abhiyutthan Singh Jadaon, performed a highly complex laparoscopic donor nephrectomy, overcoming challenges due to the mother's previous major surgery. The recipient's transplant was handled by a skilled team of nephrologists under the leadership of Dr RP Mathur, navigating critical immunological hurdles. The transplant was successful, and the son was discharged after a 10-day recovery period. This extraordinary act of love and sacrifice has given him a new lease on life, thanks to his mother's unwavering devotion. In a separate incident earlier this month on May 4, a 20-year-old driver's wife chose to donate his organs after he was declared brain dead following a tragic accident. Banoth Ramana, a resident of Warangal district in Telangana, got into an accident when a tractor suddenly collided with his two-wheeler on April 27 last month. His family rushed him to a private hospital in 9:05 PM on May 1, Ramana was declared brain dead. Ramana's wife, Kalyani, chose to donate his organs, which have given six patients a second chance at life. According to an official associated with Jeevandan, Telangana initiative, the donated organs include two kidneys, a liver, a heart, and two corneas. (ANI)

Is Your Liver In Trouble? Ways To Spot Damage At Home
Is Your Liver In Trouble? Ways To Spot Damage At Home

News18

time07-05-2025

  • Health
  • News18

Is Your Liver In Trouble? Ways To Spot Damage At Home

While most assume that liver need lab tests, India's top liver expert, Dr Sarin, says early signs like sudden weight gain and loss of appetite can be spotted at home Liver-related problems are on the rise, and not just among older adults. More and more people in their 20s and 30s are developing conditions like fatty liver and cirrhosis, often without realising it. While most assume that liver issues can only be detected through lab tests, India's top liver expert, Dr Shiv Kumar Sarin, says otherwise. According to him, there are early warning signs that can be spotted at home, if you know what to look for. Dr Sarin, Director of the Institute of Liver and Biliary Sciences (ILBS), New Delhi, mentioned in an interview with a YouTube channel that the liver is a unique organ which rarely gets damaged on its own. Unlike other organs, the liver has a natural ability to repair itself. He added that while specific symptoms of liver damage are uncommon, signs such as sudden weight gain, loss of appetite, acidity, frequent burping, and excessive snoring may indicate liver issues. The doctor explained that when patients with jaundice visit him, he often asks about their appetite. If a person feels hungry despite having jaundice, it indicates that the liver is still functioning properly. Sometimes liver problems begin due to infections. Pain on the right side of the chest could signal gallbladder stones. If liver damage is suspected, everyone should undergo annual health checks to get an accurate picture. Dr Sarin recommends getting a full body check-up once a year—ideally on your birthday or the day before—as a step towards maintaining good health. Essential tests include blood tests, lipid profile, blood sugar tests, liver ultrasound, SGPT, and ALT tests. These tests are crucial for assessing liver health. If they reveal fat deposits in the liver, it is a sign that the liver is unhealthy and needs attention. To maintain liver health, it is important to follow a balanced diet, lead a healthy lifestyle, avoid alcohol and smoking, and engage in regular physical activity. First Published: May 07, 2025, 17:01 IST

Fatty liver disease goes down with novel weight loss drugs, shows new study: What does this mean for therapy?
Fatty liver disease goes down with novel weight loss drugs, shows new study: What does this mean for therapy?

Indian Express

time02-05-2025

  • Health
  • Indian Express

Fatty liver disease goes down with novel weight loss drugs, shows new study: What does this mean for therapy?

Nearly two in three people with fatty liver disease lost some of the liver fat and inflammation after using semaglutide 2.4 mg weekly shots for one-and-a-half years, according to initial results from an ongoing phase 3 trial, published recently in the New England Journal of Medicine. Importantly, around one in three patients also saw reduction in liver fibrosis or scarring of the liver that prevents it from functioning properly. Metabolic dysfunction-Associated Steatotic Liver Disease (MAFLD) — until recently referred to as the Non-Alcoholic Fatty Liver Disease — is a chronic condition where there is an excessive build-up of fat on the liver. This fat accumulation leads to inflammation, scarring of the liver and may even cause liver cancer. The prevalence of MAFLD in India is estimated to be between 9% and 32%. Dr SK Sarin, liver specialist and vice-chancellor of the Institute of Liver and Biliary Sciences, talks about the significance of the findings. What do the results of the phase III trial tell us? This is a very important study, which builds on the findings of the phase 2 trial on the impact of semaglutide on MASLD. Phase 2 trials are usually done to fix the dosing and the highest 2.4 mg dose of the medicine was used for the current trial. The results show that 62.9% of the people on semaglutide saw a loss of liver fat and inflammation as compared to 34.3% among people given placebo. The stiffening of the liver also reduced in 36.8% of the participants on semaglutide as compared to 22.4% on placebo. The participants lost around 10% of their body weight in the current trial as compared to 14% recorded previously. All in all, the study shows promising results for fatty liver disease. How does the drug work? Are these the effects of weight loss? Semaglutide belongs to a class of medicines known as GLP-1 receptor agonists which mimic the action of certain gut hormones to improve secretion of insulin, inhibit secretion of glucagon that stimulates glucose production in the liver, and also reduce appetite by slowing down digestion. The study does not look into the confounding variable of weight loss, so we cannot say if there is any other reason for the improvements seen. However, it is well-known that when people lose weight, MASLD improves. People who lose around 7-10% of their body weight, see a reduction in liver fat. And, with a weight-loss of more than 10%, they see regression in fibrosis. This happens even if people lose weight without using these drugs. What is the current treatment for MASLD? What are the challenges? The best way to treat MASLD is weight loss — be it with drug or with diet and exercise. The drug is meant for people who are not able to move and exercise or are unable to lose weight with diet and exercise. They come with several side effects such as vomiting, nausea, and even serious side effects such as stomach paralysis, inflammation of the pancreas, and thyroid cancer. At present, there are three lines of treatment. One, of course, are the GLP-1 drugs that work on the gut hormones. Two, a drug called resmetirom that works on the thyroid hormone — this is again very expensive at around $ 5,400 a month. Third, FGF21 medicines that work on the adipose tissues. All of these medicines are meant to help with weight loss and thereby improve the liver.

Want To Keep Your Liver Healthy? Expert Reveals How Sleep And Avoiding Junk Food Can Help
Want To Keep Your Liver Healthy? Expert Reveals How Sleep And Avoiding Junk Food Can Help

India.com

time27-04-2025

  • Health
  • India.com

Want To Keep Your Liver Healthy? Expert Reveals How Sleep And Avoiding Junk Food Can Help

New Delhi: Having a good night's sleep and avoiding junk food is essential to keep the liver healthy, said Dr. S.K. Sarin, Director of the Institute of Liver and Biliary Sciences (ILBS) on Friday. He said that junk food, as the name suggests, must be put in dustbins as its regular consumption can significantly affect liver health. 'The word junk food means it is junk. It has to be put in the dustbin. But if you think your stomach and intestines are dustbins, put that food inside. Otherwise, avoid, don't use it,' Sarin said, in a post on social media platform X. Junk food which is rich in unhealthy fats, sugars, and processed ingredients increases the risk of obesity, high cholesterol, and type 2 diabetes. These diseases then raise the chances of non-alcoholic fatty liver disease (NAFLD), and progress to more serious complications like cirrhosis and liver cancer. Sarin also urged people to sleep well and not eat late as it may affect the gut bacteria, critical for better health. Studies have shown that people with poor sleep are at increased risk of fatty liver disease. Further, eating late at night has been linked to a higher risk of significant fibrosis -- a sign of liver damage. It is because the body is unable to process fat and carbohydrates during sleep, leading to their accumulation in the liver. 'Sleeping late and eating late-night food is not a great idea, because the bacteria in your intestines which process the food, will also sleep late. Restorative good sleep is the best thing,' the leading hepatologist said. Sarin advised people to not lose their health by running after 'money, power and positions'. Instead maintaining 'a sound healthy body and good night's sleep' is essential as these are the 'only two things which give happiness in life', the expert said. NAFLD, currently termed metabolic dysfunction-associated steatotic liver disease (MASLD), is a chronic liver disease that occurs when fat builds up in the liver in people who don't drink much alcohol. It can affect people with diabetes, obesity, high blood pressure, or high cholesterol. Fatty liver disease is emerging as an important cause of liver disease in India, affecting about three in 10 people in the country. In September last year, the Union Health Ministry released the revised operational guidelines and training module for MAFLD to promote early detection and help boost patient care and outcomes related to the disease.

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