Latest news with #JadIsber
Malaysian Reserve
04-08-2025
- Health
- Malaysian Reserve
Pendopharm® signs an exclusive distribution agreement with Neuraxpharm for PrBuccolam® in Canada and announces its approval by Health Canada
MONTREAL, Aug. 4, 2025 /CNW/ – Pendopharm, a division of Pharmascience Inc., is pleased to announce that it has entered into an exclusive distribution agreement with Neuraxpharm Group (Neuraxpharm), a leading European specialty pharmaceutical company focused on the treatment of central nervous system (CNS) disorders, headquartered in Düsseldorf, Germany. Under the terms of the agreement, Pendopharm® will be responsible for the commercialization of Buccolam®(Midazolam Hydrochloride Oromucosal Solution) in Canada. Buccolam® is indicated for the treatment of prolonged, acute, convulsive seizures in children. Pendopharm® is pleased to announce that Health Canada has approved Buccolam®. About Epilepsy Epilepsy is a chronic neurological disorder characterized by recurrent seizures of various types and severity. These seizures result from abnormal electrical activity in the brain and can be triggered by a range of factors, including structural abnormalities, brain inflammation, physical injury, trauma, infection, or unknown causes. It is estimated that the underlying cause of epilepsy remains undetermined in up to 50% of patients diagnosed with epilepsy. 1 Nearly 1 out of 100 Canadians live with epilepsy, and approximately 13% of them are children and youth.1 Despite treatment with anti-seizure medications, some patients may experience prolonged acute convulsive seizures which require immediate intervention. Early treatment of acute seizures is critical to prevent escalation and improve patient outcomes.2,3 Benzodiazepines, are considered first-line therapy for managing prolonged seizures.4 Buccolam® is an oromucosal solution of midazolam (a benzodiazepine) supplied in a ready-to-use, pre-filled syringes for buccal (absorbed in the mouth) administration.5 'Prolonged convulsive seizures in pediatric patients can have significant short- and long-term impacts', said Dr. Aris Hadjinicolaou, Pediatric Neurologist at CHU Sainte-Justine. 'Having access to a ready-to-use, on-label medication could facilitate timely intervention during seizures and may decrease the need for emergency medical services'. 'This partnership represents Pendopharm's commitment to bringing medicines that address unmet medical needs to Canadian patients,' said Jad Isber, Vice President & General Manager of Pendopharm®. 'We look forward to working with Canadian neurologists and pediatricians to make Buccolam available to all patients who may benefit from it.' Dr. Maximilian von Wülfing, Chief Operating Officer of Neuraxpharm, said: 'Through its network of strategic partnerships around the world, Neuraxpharm is committed to expanding access to market-leading medicines. Our collaboration with Pendopharm further strengthens our position as a global CNS specialist enabling us to deliver an epilepsy treatment designed to reduce hospitalizations and provide support to patients and their caregivers.' About Pendopharm® Pendopharm, specialty division of Pharmascience Inc., is a leading Canadian specialty pharmaceutical company providing patients with innovative medicines that address unmet medical needs. Its areas of focus are gastroenterology, sports medicine & orthopedics, neurology and cardiology. Pendopharm® has extensive experience and knowledge to successfully manage its growing product portfolio. For more information, please visit For media inquiries, please contact MediaInquiries@ © 2025 Pendopharm, division of Pharmascience Inc. All rights reserved. About Pharmascience Inc. Pharmascience Inc. is one of the largest pharmaceutical manufacturers in Canada and is headquartered in Montreal, Canada. Pharmascience delivers high-quality medicines to over 50 countries worldwide. Pharmascience Inc.'s global presence and agile business development model provide healthcare communities around the world with the high-quality Canadian medicines to respond to patients' needs. About the Neuraxpharm Group Neuraxpharm is a leading European specialty pharmaceutical company focused on the treatment of the central nervous system (CNS), including both psychiatric and neurological disorders. It has a unique understanding of the CNS market built over 40 years. Neuraxpharm is constantly innovating, with new products and solutions to address unmet patient needs and is expanding its portfolio through its pipeline, partnerships and acquisitions. The company has c.1,000 employees and develops and commercialises CNS products through a direct presence in more than 20 countries in Europe, two in Latin America, one in the Middle East, one in Australia, and globally via partners in more than 50 countries. Neuraxpharm is backed by funds advised by Permira. Neuraxpharm manufactures many of its pharmaceutical products at Neuraxpharm Pharmaceuticals (formerly Laboratorios Lesvi) in Spain. For more information, please visit For more information, please contact: Neuraxpharm@ Pendopharm® and Design are registered trademarks owned by Finchley Research and Development Inc. Buccolam® is a registered trademark owned by Neuraxpharm, used under license by Pendopharm, a division of Pharmascience Inc. References: What is epilepsy? — Epilepsy Canada Epilepsie – consulted June 25th, 2025 Standard of Care and Role of Rescue Medications in Epilepsy Epilepsy Treatment | Treating Seizures | Epilepsy Foundation Seizure Rescue Medications | Types of Epilepsy Medications – consulted June 25th, 2025 Buccolam® Product Monograph. July 2025. Epilepsy in Canada – (gov Canada statistics) – consulted June 25th, 2025
Cision Canada
04-08-2025
- Health
- Cision Canada
Pendopharm® signs an exclusive distribution agreement with Neuraxpharm for PrBuccolam® in Canada and announces its approval by Health Canada Français
MONTREAL, Aug. 4, 2025 /CNW/ - Pendopharm, a division of Pharmascience Inc., is pleased to announce that it has entered into an exclusive distribution agreement with Neuraxpharm Group (Neuraxpharm), a leading European specialty pharmaceutical company focused on the treatment of central nervous system (CNS) disorders, headquartered in Düsseldorf, Germany. Under the terms of the agreement, Pendopharm ® will be responsible for the commercialization of Buccolam ® (Midazolam Hydrochloride Oromucosal Solution) in Canada. Buccolam ® is indicated for the treatment of prolonged, acute, convulsive seizures in children. Pendopharm ® is pleased to announce that Health Canada has approved Buccolam ®. About Epilepsy Epilepsy is a chronic neurological disorder characterized by recurrent seizures of various types and severity. These seizures result from abnormal electrical activity in the brain and can be triggered by a range of factors, including structural abnormalities, brain inflammation, physical injury, trauma, infection, or unknown causes. It is estimated that the underlying cause of epilepsy remains undetermined in up to 50% of patients diagnosed with epilepsy. 1 Nearly 1 out of 100 Canadians live with epilepsy, and approximately 13% of them are children and youth. 1 Despite treatment with anti-seizure medications, some patients may experience prolonged acute convulsive seizures which require immediate intervention. Early treatment of acute seizures is critical to prevent escalation and improve patient outcomes. 2,3 Benzodiazepines, are considered first-line therapy for managing prolonged seizures. 4 Buccolam ® is an oromucosal solution of midazolam (a benzodiazepine) supplied in a ready-to-use, pre-filled syringes for buccal (absorbed in the mouth) administration. 5 "Prolonged convulsive seizures in pediatric patients can have significant short- and long-term impacts", said Dr. Aris Hadjinicolaou, Pediatric Neurologist at CHU Sainte-Justine. "Having access to a ready-to-use, on-label medication could facilitate timely intervention during seizures and may decrease the need for emergency medical services". " This partnership represents Pendopharm's commitment to bringing medicines that address unmet medical needs to Canadian patients," said Jad Isber, Vice President & General Manager of Pendopharm ®. "We look forward to working with Canadian neurologists and pediatricians to make Buccolam available to all patients who may benefit from it." Dr. Maximilian von Wülfing, Chief Operating Officer of Neuraxpharm, said: "Through its network of strategic partnerships around the world, Neuraxpharm is committed to expanding access to market-leading medicines. Our collaboration with Pendopharm further strengthens our position as a global CNS specialist enabling us to deliver an epilepsy treatment designed to reduce hospitalizations and provide support to patients and their caregivers." About Pendopharm ® Pendopharm, specialty division of Pharmascience Inc., is a leading Canadian specialty pharmaceutical company providing patients with innovative medicines that address unmet medical needs. Its areas of focus are gastroenterology, sports medicine & orthopedics, neurology and cardiology. Pendopharm ® has extensive experience and knowledge to successfully manage its growing product portfolio. For more information, please visit For media inquiries, please contact [email protected]. © 2025 Pendopharm, division of Pharmascience Inc. All rights reserved. About Pharmascience Inc. Pharmascience Inc. is one of the largest pharmaceutical manufacturers in Canada and is headquartered in Montreal, Canada. Pharmascience delivers high-quality medicines to over 50 countries worldwide. Pharmascience Inc.'s global presence and agile business development model provide healthcare communities around the world with the high-quality Canadian medicines to respond to patients' needs. About the Neuraxpharm Group Neuraxpharm is a leading European specialty pharmaceutical company focused on the treatment of the central nervous system (CNS), including both psychiatric and neurological disorders. It has a unique understanding of the CNS market built over 40 years. Neuraxpharm is constantly innovating, with new products and solutions to address unmet patient needs and is expanding its portfolio through its pipeline, partnerships and acquisitions. The company has c.1,000 employees and develops and commercialises CNS products through a direct presence in more than 20 countries in Europe, two in Latin America, one in the Middle East, one in Australia, and globally via partners in more than 50 countries. Neuraxpharm is backed by funds advised by Permira. Neuraxpharm manufactures many of its pharmaceutical products at Neuraxpharm Pharmaceuticals (formerly Laboratorios Lesvi) in Spain. For more information, please visit .
Cision Canada
26-06-2025
- Business
- Cision Canada
Pendopharm® and KalVista® Partner to Bring First Oral On-Demand HAE Treatment to Canada Français
MONTREAL, June 26, 2025 /CNW/ - Pendopharm®, a division of Pharmascience Inc., has entered into an exclusive distribution agreement with KalVista Pharmaceuticals, Inc. (NASDAQ: KALV), a global biopharmaceutical company focused on the development of novel oral treatments for rare diseases. This agreement grants Pendopharm® the rights to manage regulatory approval and commercialization of sebetralstat, an investigational oral therapy for Hereditary Angioedema (HAE), developed by KalVista® in Canada. Financial details of the agreement remain confidential. Sebetralstat is poised to become the first oral on-demand treatment for hereditary angioedema in Canada. This treatment addresses a critical need for patients living with HAE - a rare and potentially life-threatening genetic disorder marked by unpredictable episodes of severe swelling. ¹ "HAE can significantly disrupt patients' lives due to sudden, severe and potentially life threatening attacks of swelling" said Dr. Stephen Betschel, Chair of the Canadian Hereditary Angioedema Network. "This potential new therapeutic option would be welcomed, and would represent a significant advancement in the treatment of HAE in Canada". Jad Isber, Vice President & General Manager of Pendopharm®, emphasized the company's dedication to patient care: "This collaboration reflects our mission to deliver therapies that address unmet medical needs. We look forward to working with healthcare providers across Canada to ensure access to sebetralstat for those who need it." "We are pleased to partner with Pendopharm®, whose expertise in the Canadian healthcare landscape and established success in pharmaceutical commercialization make them a well-suited collaborator," said Ben Palleiko, CEO of KalVista®. "This agreement advances our mission to make sebetralstat accessible worldwide as the first and only oral on-demand treatment with the potential to change the way HAE is managed." About Sebetralstat Sebetralstat is an investigational oral therapy developed for the on-demand treatment of acute HAE attacks. It is currently under regulatory review in several countries as a potential oral therapy for hereditary angioedema (HAE). ¹ About Hereditary Angioedema (HAE) HAE is severe swelling (angioedema) in various parts of the body, including the hands, feet, genitals, stomach, face and/or throat. Swelling in the airway can restrict breathing and be fatal. The vast majority of people with HAE have a genetic defect that causes a deficiency in the plasma protein called C1-Inhibitor. HAE is also seen in people who have normal levels of C1-Inhibitor, however, genetic defects in other genes cause their angioedema. ² About Pendopharm Pendopharm®, a division of Pharmascience Inc., is a Canadian specialty pharmaceutical company that partners with various companies to bring treatments in areas such as rare diseases, gastroenterology, sports medicine, neurology, and cardiology to the Canadian market. For more information about Pendopharm®, please visit Please do not further distribute this press release. © 2025 Pendopharm®, division of Pharmascience Inc. All rights reserved. Pendopharm® is a registered trademark owned by Finchley Research and Development Inc., used under license by Pharmascience Inc. Kalvista® is a registered trademark owned by Kalvista Pharmaceuticals Limited. About Pharmascience Inc. Headquartered in Montreal, Pharmascience Inc. is one of Canada's largest pharmaceutical manufacturers, supplying high-quality medicines to over 50 countries. Its global reach and agile development model ensure timely responses to patient needs worldwide. About KalVista Pharmaceuticals, Inc. KalVista Pharmaceuticals, Inc., is a global biopharmaceutical company dedicated to developing and delivering life-changing oral therapies for individuals affected by rare diseases with significant unmet needs. Our lead investigational product is sebetralstat, a novel, oral, on-demand treatment for hereditary angioedema (HAE). Sebetralstat is under regulatory review by the U.S. FDA. In addition, we have completed Marketing Authorization Applications for sebetralstat to the European Medicines Agency and multiple other global regulatory authorities.
