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Exercise may reduce risk of cancer returning, study shows
Exercise may reduce risk of cancer returning, study shows

RTÉ News​

time3 days ago

  • Health
  • RTÉ News​

Exercise may reduce risk of cancer returning, study shows

An international cancer study has found that exercise can have huge benefits for cancer patients and can even reduce the risk of the disease returning. The results were presented at the American Society of Clinical Oncology annual conference in Chicago at the weekend, and published in the New England Journal of Medicine. Among those attending the expert gathering was Professor Janice Walshe, medical oncologist at St Vincent's University Hospital in Dublin. She called the study an "incredibly strong finding", saying "it adds to the literatures that suggests that exercise is really important in keeping ourselves well." The study examined nearly 890 patients who had high risk colon cancers (stage 2 or stage 3) and was completed in 55 locations, including in countries such as the US, France and Australia. All patients had completed chemotherapy treatments and were put into one of two groups. One group was given structured, supervised exercise sessions with a personal trainer and the other was just given a booklet outlining the benefits of a healthy lifestyle. The first group did 45 to 60 minute walks three or four times a week and could do more if they chose. Twice a month they worked with a personal trainer and then later once a month for a total of three years. After eight years, the patients in the first group had a 37% lower risk of dying than those in the second group. Prof Walshe said it was important to note that all these patients had already received chemotherapy. "So, this intervention is not a substitute for drugs that we know already reduce the risk of people dying from different various cancers," Prof Walsh said. Speaking to RTÉ's Morning Ireland, Prof Walshe said she felt that some newspaper headlines about the study were "misleading." "I think what they're trying to say is that the magnitude of benefit we have seen with this intervention, of an exercise programme, is the type of reductions we've seen with many of our new drugs. "But this is not a drug substitute," Prof Walshe said. "This is on top of you receiving the best drugs in the market to reduce the risk of disease recurrence." Prof Walshe said there is a "huge amount of Irish research" at this year's American Society of Clinical Oncology conference. "The consultants who travel here are all networking with various research groups to bring these trials home to Ireland and obviously the best approaches in terms of managing our cancer in our Irish patients," she said. "We already have exercise programmes ongoing in various parts of the country that are free of charge, because we believe exercise is really important in terms of, one, reducing risk of disease recurrence and, two, increasing people's confidence," she added.

New breast cancer treatment that avoids chemotherapy saves woman almost €43k in lost income avoided
New breast cancer treatment that avoids chemotherapy saves woman almost €43k in lost income avoided

Irish Examiner

time21-05-2025

  • Health
  • Irish Examiner

New breast cancer treatment that avoids chemotherapy saves woman almost €43k in lost income avoided

A new approach to breast cancer care in Ireland, which avoids chemotherapy, is saving each woman almost €43,000 and health services €152m annually across all patients who benefit. Data gathered on 577 patients attending four Irish hospitals showed for the first time the wider benefits of the Oncotype DX test approach in addition to health boosts. Some 412 of these women were able to avoid chemotherapy after this test identified they could safety have other treatment instead. This means they did not suffer the debilitating side-effects of chemotherapy. In addition, this study shows they needed less time off work during treatment, which is estimated to have saved each woman €42,924 in average lost income avoided. The women also skipped appointment-related costs estimated at €1,059. The Irish Cancer Society previously described these hidden costs as 'an often overlooked burden'. The hospitals, all in Dublin, experienced a significant drop in demand, as these women needed 7,186 fewer hospital visits, 15,386 fewer hospital hours, and 187 fewer inpatient days. Across the group of 577 patients, they needed 3,284 fewer chemotherapy cycles, which this study estimated is equivalent to 10,052 when extrapolated nationally. On the broader economic impact, the study estimated €49.8m in societal chemotherapy cost savings. This comes to €152m when extrapolated nationally, a spokesman said. They also estimated €4.7m in direct healthcare savings, coming to €14.5m when extrapolated nationally. Lead author Professor Janice Walshe said 'The use of the 21 gene score in the management of breast cancer has resulted in over 70% of patients with early-stage hormone sensitive and HER-2 negative breast cancer avoiding chemotherapy.' Prof Walshe, a consultant medical oncologist at St Vincent's Hospital and senior lecturer at UCD and Trinity College Dublin, said the findings have "wide reaching impacts for patients, their families and wider society.' 'While we have previously demonstrated cost savings from this gene expression test, our latest analysis — which incorporates the societal cost of chemotherapy — shows a national saving of €152m.' The research, 'The Impact of Predictive Genomic Testing in Ireland: Financial and Resource Implications for Healthcare Institutions and Patients', was published at the European Society of Medical Oncology Breast Cancer 2025 conference in Munich this week. Meanwhile, the Irish Pharmaceutical Healthcare Association welcomed a 34% increase in pharmaceutical industry-sponsored clinical trials started in Ireland last year compared to 2023. The average time to recruit the first patient into a trial dropped by 31%. However IPHA also warned on Tuesday: 'Despite these positive steps, Ireland still lags many of its European peers. In 2024, Ireland ranked 18th out of 27 EU countries in clinical trials per capita.'

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