Latest news with #JasperTherapeutics
Yahoo
2 days ago
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Jasper Therapeutics Announces Briquilimab Presentations at the European Academy of Allergy and Clinical Immunology (EAACI) Annual Congress
REDWOOD CITY, Calif., June 03, 2025 (GLOBE NEWSWIRE) -- Jasper Therapeutics, Inc. (Nasdaq: JSPR) (Jasper), a clinical stage biotechnology company focused on development of briquilimab, a novel antibody therapy targeting c-Kit (CD117) to address mast cell driven diseases such as chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU) and asthma, today announced that four abstracts have been accepted for presentation at the EAACI Congress 2025, to be held June 13-16, 2025 in Glasgow, United Kingdom. Jasper will present initial clinical data from patients enrolled in the 180mg cohort of the SPOTLIGHT Phase 1b/2a study evaluating briquilimab in subcutaneous briquilimab in cold urticaria (ColdU) or symptomatic dermographism (SD) during an oral session on Saturday, June 14. Details of the presentations are as follows: Abstract Title: Initial Results from SPOTLIGHT, a Phase 1b/2a Dose Escalation Study of the anti-c-Kit Briquilimab Antibody in Adults with Inducible Urticaria (CIndU) Who Remain Symptomatic Despite H-1 Antihistamine TreatmentAbstract Number: 269Session Type/Title: Oral Abstract Session on Clinical Trials (OAS-CT2, Clinical Trials on Dermatology) Presentation Date/Time: June 14, 3:00-4:30pm Abstract Title: A Single Dose of Briquilimab, an Anti-Human c-Kit (CD117)-Antibody, Protects Against Relapse of Epicutaneous Allergen-Induced Dermatitis in Mice Expressing Chimeric Human/Mouse CD117Abstract Number: 523Session Type/Title: Thematic Poster Session (Biologicals 02)Presentation Date/Time: June 14, 12:00-1:00pm Abstract Title: Briquilimab Demonstrates Rapid, Clinically Meaningful Disease-Control in Adults with Chronic Spontaneous Urticaria (CSU): Updated Results from Phase 1b/2a StudyAbstract Number: 100281Session Type/Title: Flash Talk (L-FT08 Dermatology) Presentation Date/Time: June 15, 12:45-1:45pm Abstract Title: Targeting Mast Cells with Briquilimab, an Anti-Human c-Kit (CD117)-Antibody, Mitigates COPD-Like Features in an Allergen and Cigarette Smoke-Exacerbated Asthma Model Using Humanized h/mCD117 MiceAbstract Number: 537Session Type/Title: Thematic Poster Session (Asthma 07),Presentation Date/Time: June 15, 12:45-1:45pm About Jasper Jasper is a clinical-stage biotechnology company focused on developing briquilimab as a therapeutic for chronic mast cell diseases. Briquilimab is a targeted aglycosylated monoclonal antibody that blocks stem cell factor from binding to the cell-surface receptor KIT, thereby inhibiting signaling through the receptor. This inhibition disrupts the critical survival signal, leading to the depletion of the mast cells via apoptosis which removes the underlying source of the inflammatory response in mast cell driven diseases such as chronic urticaria and asthma. Jasper is currently conducting clinical studies of briquilimab as a treatment in patients with CSU, CIndU or asthma. Briquilimab has a demonstrated efficacy and safety profile in patients and healthy volunteers, with positive clinical outcomes in CSU and CIndU. For more information, please visit us at Forward-Looking Statements Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as 'believe,' 'may,' 'will,' 'estimate,' 'continue,' 'anticipate,' 'intend,' 'expect,' 'should,' 'would,' 'plan,' 'predict,' 'potential,' 'seem,' 'seek,' 'future,' 'outlook' and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding briquilimab's potential, including with respect to its potential in mast cell driven diseases such as CSU, CIndU, and asthma; and Jasper's presentations at the EAACI Annual Congress. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of Jasper and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied on by an investor as, a guarantee, an assurance, a prediction or a definitive statement of fact or probability. Many actual events and circumstances are beyond the control of Jasper. These forward-looking statements are subject to a number of risks and uncertainties, including general economic, political and business conditions; the risk that the potential product candidates that Jasper develops may not progress through clinical development or receive required regulatory approvals within expected timelines or at all; the risk that clinical trials may not confirm any safety, potency or other product characteristics described or assumed in this press release; the risk that prior test, study and trial results may not be replicated in continuing or future studies and trials; the risk that Jasper will be unable to successfully market or gain market acceptance of its product candidates; the risk that prior study results may not be replicated; the risk that Jasper's product candidates may not be beneficial to patients or successfully commercialized; patients' willingness to try new therapies and the willingness of physicians to prescribe these therapies; the effects of competition on Jasper's business; the risk that third parties on which Jasper depends for laboratory, clinical development, manufacturing and other critical services will fail to perform satisfactorily; the risk that Jasper's business, operations, clinical development plans and timelines, and supply chain could be adversely affected by the effects of health epidemics; the risk that Jasper will be unable to obtain and maintain sufficient intellectual property protection for its investigational products or will infringe the intellectual property protection of others; and other risks and uncertainties indicated from time to time in Jasper's filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2024 and subsequent Quarterly Reports on Form 10-Q. If any of these risks materialize or Jasper's assumptions prove incorrect, actual results could differ materially from the results implied by these forward-looking statements. While Jasper may elect to update these forward-looking statements at some point in the future, Jasper specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Jasper's assessments of any date subsequent to the date of this press release. Accordingly, undue reliance should not be placed upon the forward-looking statements. Contacts: Alex Gray (investors)Jasper Therapeutics650-549-1454 agray@ Allaire (investors)LifeSci Advisors617-435-6602jallaire@ Lauren Walker (media)Real Chemistry646-564-2156lbarbiero@ in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
21-05-2025
- Business
- Yahoo
Jasper Therapeutics, Inc. (JSPR): Analysts See 914% Upside Potential
We recently published an article titled . Jasper Therapeutics, Inc. (JSPR) was one of the stocks that was covered in that article. Wall Street analysts believe JSPR has a 914% upside potential over the next 12 months. A biotech scientist studying a microscope slide filled with hematopoietic stem cells. Jasper Therapeutics, Inc. (NASDAQ:JSPR) is a clinical-stage biotechnology company that focuses on developing therapeutics targeting mast and hematopoietic stem cell-driven diseases. Its lead product candidate is briquilimab, a monoclonal antibody designed to block stem cell factor from binding to and signaling through the CD117 receptor on mast and stem cells. JSPR focuses on the development and commercialization of therapeutic agents for patients with various mast cell-driven diseases, including chronic spontaneous urticaria, chronic inducible urticaria, and asthma, as well as conditioning agents for stem cell transplant in patients with sickle cell disease, Fanconi anemia, and severe combined immunodeficiency. In terms of marketing and distribution, Jasper Therapeutics, Inc. (NASDAQ:JSPR) has established exclusive licensing agreements with Amgen and Stanford University for the development and commercialization of briquilimab. These collaborations are crucial for advancing the company's product candidates and expanding its research capabilities. The company stated on its website: "We have an exclusive license agreement with Amgen Inc. ('Amgen') for the development and commercialization of the briquilimab monoclonal antibody in all indications and territories worldwide." It must be noted that Jasper Therapeutics, Inc. (NASDAQ:JSPR) reported a net loss of $21.2 million for the first quarter of 2025, which was significantly higher than the previous year. This reflects increased operating expenses, primarily in research and development. The company's cash balance stands at $49.2 million as of March 31, 2025. Meanwhile, operating expenses were higher at $15.1 million, with research and development expenses rising from $10.3 million to $16.2 million, both on a year-on-year comparison. Ronald Martell, President and Chief Executive Officer of Jasper spoke on the company's performance: 'During the first quarter of 2025 we made great progress advancing briquilimab toward important data readouts later this year from all three of our clinical programs in mast cell diseases'. On May 15, 2025, Oppenheimer analyst Jay Olson issued an update on Jasper Therapeutics (JSPR, Financial), reaffirming the firm's 'Outperform' rating for the company but revising the price target. Analysts on Wall Street following the stock hold an optimistic view of the company, with a 'Strong Buy' rating and a consensus on the average price for the next twelve months estimated at $49.89, an upside of 914%. Overall, Jasper Therapeutics, Inc. (NASDAQ:JSPR) ranks 1st on our list of 13 Best Multibagger Stocks to Invest in Now. While we acknowledge the potential of JSPR to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than JSPR and that has 100x upside potential, check out our report about this cheapest AI stock. READ NEXT: 10 Best Low Volatility Stocks to Buy Now and Starter Stock Portfolio: 12 Safe Stocks to Buy Disclosure: None. This article is originally published at Insider Monkey. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
21-05-2025
- Business
- Yahoo
Jasper Therapeutics, Inc. (JSPR): Analysts See 914% Upside Potential
We recently published an article titled . Jasper Therapeutics, Inc. (JSPR) was one of the stocks that was covered in that article. Wall Street analysts believe JSPR has a 914% upside potential over the next 12 months. A biotech scientist studying a microscope slide filled with hematopoietic stem cells. Jasper Therapeutics, Inc. (NASDAQ:JSPR) is a clinical-stage biotechnology company that focuses on developing therapeutics targeting mast and hematopoietic stem cell-driven diseases. Its lead product candidate is briquilimab, a monoclonal antibody designed to block stem cell factor from binding to and signaling through the CD117 receptor on mast and stem cells. JSPR focuses on the development and commercialization of therapeutic agents for patients with various mast cell-driven diseases, including chronic spontaneous urticaria, chronic inducible urticaria, and asthma, as well as conditioning agents for stem cell transplant in patients with sickle cell disease, Fanconi anemia, and severe combined immunodeficiency. In terms of marketing and distribution, Jasper Therapeutics, Inc. (NASDAQ:JSPR) has established exclusive licensing agreements with Amgen and Stanford University for the development and commercialization of briquilimab. These collaborations are crucial for advancing the company's product candidates and expanding its research capabilities. The company stated on its website: "We have an exclusive license agreement with Amgen Inc. ('Amgen') for the development and commercialization of the briquilimab monoclonal antibody in all indications and territories worldwide." It must be noted that Jasper Therapeutics, Inc. (NASDAQ:JSPR) reported a net loss of $21.2 million for the first quarter of 2025, which was significantly higher than the previous year. This reflects increased operating expenses, primarily in research and development. The company's cash balance stands at $49.2 million as of March 31, 2025. Meanwhile, operating expenses were higher at $15.1 million, with research and development expenses rising from $10.3 million to $16.2 million, both on a year-on-year comparison. Ronald Martell, President and Chief Executive Officer of Jasper spoke on the company's performance: 'During the first quarter of 2025 we made great progress advancing briquilimab toward important data readouts later this year from all three of our clinical programs in mast cell diseases'. On May 15, 2025, Oppenheimer analyst Jay Olson issued an update on Jasper Therapeutics (JSPR, Financial), reaffirming the firm's 'Outperform' rating for the company but revising the price target. Analysts on Wall Street following the stock hold an optimistic view of the company, with a 'Strong Buy' rating and a consensus on the average price for the next twelve months estimated at $49.89, an upside of 914%. Overall, Jasper Therapeutics, Inc. (NASDAQ:JSPR) ranks 1st on our list of 13 Best Multibagger Stocks to Invest in Now. While we acknowledge the potential of JSPR to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than JSPR and that has 100x upside potential, check out our report about this cheapest AI stock. READ NEXT: 10 Best Low Volatility Stocks to Buy Now and Starter Stock Portfolio: 12 Safe Stocks to Buy Disclosure: None. This article is originally published at Insider Monkey. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
14-05-2025
- Business
- Yahoo
Jasper Therapeutics to Present at Upcoming Investor Conferences
REDWOOD CITY, Calif., May 14, 2025 (GLOBE NEWSWIRE) -- Jasper Therapeutics, Inc. (Nasdaq: JSPR) (Jasper), a clinical stage biotechnology company focused on development of briquilimab, a novel antibody therapy targeting KIT to address mast cell driven diseases such as chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU) and asthma, today announced that management will participate in the following investor conferences: RBC Capital Markets 2025 Global Healthcare Conference Conference Dates: May 20-21, 2025Presentation Date/Time: Wednesday, May 21, 2025; 11:00 a.m. EDTPresentation Format: Fireside Chat Jefferies 2025 Global Healthcare ConferenceConference Dates: June 3-5, 2025Presentation Date/Time: Thursday, June 5, 2025; 11:40 a.m. EDTPresentation Format: Presentation Live webcasts of the presentations will be available on the News & Events – Events page of Jasper's Investor Relations website. An archived replay of each presentation will be available on Jasper's website for 30 days following the applicable live broadcast. About Jasper Jasper is a clinical-stage biotechnology company focused on developing briquilimab as a therapeutic for chronic mast cell diseases. Briquilimab is a targeted aglycosylated monoclonal antibody that blocks stem cell factor from binding to the cell-surface receptor KIT, thereby inhibiting signaling through the receptor. This inhibition disrupts the critical survival signal, leading to the depletion of the mast cells via apoptosis which removes the underlying source of the inflammatory response in mast cell driven diseases such as chronic urticaria and asthma. Jasper is currently conducting clinical studies of briquilimab as a treatment in patients with CSU, CIndU or asthma. Briquilimab has a demonstrated efficacy and safety profile in patients and healthy volunteers, with positive clinical outcomes in CSU and CIndU. For more information, please visit us at Forward-Looking Statements Certain statements included in this press release that are not historical facts are forward-looking statements for purposes of the safe harbor provisions under the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements are sometimes accompanied by words such as 'believe,' 'may,' 'will,' 'estimate,' 'continue,' 'anticipate,' 'intend,' 'expect,' 'should,' 'would,' 'plan,' 'predict,' 'potential,' 'seem,' 'seek,' 'future,' 'outlook' and similar expressions that predict or indicate future events or trends or that are not statements of historical matters. These forward-looking statements include, but are not limited to, statements regarding briquilimab's potential, including with respect to its potential in mast cell driven diseases such as CSU, CIndU, and asthma; and Jasper's participation in the RBC Capital Markets 2025 Global Healthcare Conference and the Jefferies 2025 Global Healthcare Conference. These statements are based on various assumptions, whether or not identified in this press release, and on the current expectations of Jasper and are not predictions of actual performance. These forward-looking statements are provided for illustrative purposes only and are not intended to serve as, and must not be relied on by an investor as, a guarantee, an assurance, a prediction or a definitive statement of fact or probability. Many actual events and circumstances are beyond the control of Jasper. These forward-looking statements are subject to a number of risks and uncertainties, including general economic, political and business conditions; the risk that the potential product candidates that Jasper develops may not progress through clinical development or receive required regulatory approvals within expected timelines or at all; the risk that clinical trials may not confirm any safety, potency or other product characteristics described or assumed in this press release; the risk that prior test, study and trial results may not be replicated in continuing or future studies and trials; the risk that Jasper will be unable to successfully market or gain market acceptance of its product candidates; the risk that prior study results may not be replicated; the risk that Jasper's product candidates may not be beneficial to patients or successfully commercialized; patients' willingness to try new therapies and the willingness of physicians to prescribe these therapies; the effects of competition on Jasper's business; the risk that third parties on which Jasper depends for laboratory, clinical development, manufacturing and other critical services will fail to perform satisfactorily; the risk that Jasper's business, operations, clinical development plans and timelines, and supply chain could be adversely affected by the effects of health epidemics; the risk that Jasper will be unable to obtain and maintain sufficient intellectual property protection for its investigational products or will infringe the intellectual property protection of others; and other risks and uncertainties indicated from time to time in Jasper's filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2024 and subsequent Quarterly Reports on Form 10-Q. If any of these risks materialize or Jasper's assumptions prove incorrect, actual results could differ materially from the results implied by these forward-looking statements. While Jasper may elect to update these forward-looking statements at some point in the future, Jasper specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing Jasper's assessments of any date subsequent to the date of this press release. Accordingly, undue reliance should not be placed upon the forward-looking statements. Contacts: Alex Gray (investors)Jasper Therapeutics650-549-1454 agray@ Joyce Allaire (investors)LifeSci Advisors617-435-6602jallaire@ Lauren Walker (media)Real Chemistry646-564-2156lbarbiero@
Business Insider
13-05-2025
- Business
- Business Insider
TD Cowen Keeps Their Buy Rating on Jasper Therapeutics (JSPR)
In a report released yesterday, Yaron Werber from TD Cowen maintained a Buy rating on Jasper Therapeutics (JSPR – Research Report). The company's shares closed yesterday at $4.74. Protect Your Portfolio Against Market Uncertainty Discover companies with rock-solid fundamentals in TipRanks' Smart Value Newsletter. Receive undervalued stocks, resilient to market uncertainty, delivered straight to your inbox. Werber covers the Healthcare sector, focusing on stocks such as Ionis Pharmaceuticals, Argenx Se, and Amgen. According to TipRanks, Werber has an average return of 5.2% and a 46.89% success rate on recommended stocks. Jasper Therapeutics has an analyst consensus of Strong Buy, with a price target consensus of $60.38. Based on Jasper Therapeutics' latest earnings release for the quarter ending December 31, the company reported a quarterly revenue of $1.17 million and a net profit of $46.95 million. In comparison, last year the company earned a revenue of $2.05 million and had a GAAP net loss of $16.58 million
