Latest news with #JournalofClinicalandAestheticDermatology
India Today
20 hours ago
- Health
- India Today
Truth about dark underarms: It's a health issue, not a beauty fad
When Aarti turned 24, she stopped wearing sleeveless tops-not because of modesty, but because her underarms had darkened noticeably over the past few years. She tried whitening deodorants, lightening serums, even homemade scrubs made of lemon and turmeric. Nothing worked."I thought I wasn't doing enough self-care," she says, "until my doctor told me it had nothing to do with my hygiene-and everything to do with my hormones."Dark underarms, knees, neck folds, and inner thighs are often sold to us as aesthetic flaws. But in reality, these patches may be early warning signs of underlying metabolic or endocrine SCIENCE BEHIND SKIN DARKENINGSkin darkening in folds like the underarms, groin, or neck is often caused by a condition called acanthosis nigricans (AN). This isn't a skin issue; it's a systemic signal. AN is most commonly linked to:Insulin resistancePolycystic Ovary Syndrome (PCOS)ObesityType 2 DiabetesThyroid disordersAccording to a 2019 study published in the Journal of Clinical and Aesthetic Dermatology, up to 74% of people with acanthosis nigricans also have insulin resistance. The darkening occurs when high insulin levels stimulate skin cells (keratinocytes) to grow more rapidly and produce extra pigment (melanin).HORMONES, FRICTION, AND MELANIN: THE REAL CULPRITS It's not dirt. It's not poor hygiene. It's from tight clothing or frequent shaving can worsen darkening by causing chronic low-grade inflammation. Hormonal imbalances, particularly from conditions like PCOS, can increase melanin production. Obesity adds skin folds and raises insulin levels, both of which accelerate BEAUTY INDUSTRY'S DANGEROUS NARRATIVEadvertisementDespite clear links to health issues, many beauty brands continue to market dark underarms as a cosmetic flaw. A 2021 market report by Statista estimated the global skin-lightening industry to be worth over $8.3 billion, with underarm and intimate area creams gaining popularity in Asia and Africa."Many fairness or underarm-lightening creams contain harmful ingredients like hydroquinone, mercury, or high-dose steroids," says Dr. Roshni Deshmukh, a dermatologist in Mumbai. "They might offer temporary results, but can damage the skin barrier or cause rebound pigmentation. Worse, they distract from the real issue which may be internal."WHEN TO SEE A DOCTOR INSTEAD OF A DERMATOLOGISTIf you have dark patches in more than one fold (underarms, groin, neck, knuckles), and especially if you also have irregular periods, fatigue, or sudden weight gain, consult a physician, not just a skincare for:Blood sugar / HbA1cThyroid functionHormonal panels (PCOS/androgens)WHAT ACTUALLY HELPSAddressing insulin resistance through diet, exercise, and medication (like Metformin)Weight managementSwitching to gentle, non-frictional hygiene productsOpical retinoids or azelaic acid, under prescriptionLet's Stop Shaming Skin for SpeakingYour skin is a messenger, not a mistake. It's time we stop blaming ourselves or our bodies for changes that are natural or symptomatic."I wasted so much time and money on underarm creams," Aarti says. "I wish someone had told me it was my body asking for help."- Ends
Yahoo
03-03-2025
- Health
- Yahoo
skinbetter science® Launches BioRewind Skin Health Dietary Supplement to Combat Skin Glycation
Clinically demonstrated formula designed to help to reverse the visible effects of glycation, a key contributor to skin aging Data to be presented via two posters at the Annual American Academy of Dermatology (AAD) Meeting in Orlando, FL LOS ANGELES, March 3, 2025 /PRNewswire/ -- skinbetter science® a leader in advanced skincare solutions, today announced the launch of BioRewind™, a skin health dietary supplement to improve visible skin quality by helping reduce Advanced Glycation Endproducts (AGEs). Glycation is a natural process where sugars bind to proteins, such as collagen and elastin, forming harmful substances called AGEs, which can stiffen these proteins and accelerate visible signs of aging. Without intervention, glycated collagen accumulates at an average annual rate of 3.7%.2 BioRewind leverages proprietary CORExtract biotechnology comprises of rosemary extract and potent bioactive co-factors which help reverse the cumulative effects of early-stage glycation and skin aging at the source, resulting in healthier and younger looking skin. "The launch of BioRewind marks a significant milestone for skinbetter science and medical grade skincare," said Jonah Shacknai, CEO of skinbetter science®. "With BioRewind, we are introducing a new approach to counteract skin aging by addressing glycation, a lesser-known but extremely critical factor in the skin aging process. We are confident this innovation will redefine how we think about skin health." A double-blinded, randomized, placebo-controlled trial evaluated the safety and efficacy of BioRewind ™ in 104 patients over 12-weeks. Key results showed that after 12-weeks, patients in the BioRewind treatment group experienced significant reductions compared to baseline: 30% reduction in rough skin texture 28% reduction in skin dullness 14% reduction in skin redness Additionally, at 12 weeks a 17% improvement in global skin quality was achieved in patients in the BioRewind treatment group compared to their baseline of the results were statistically significant Clinical and histological evidence will be available at the upcoming American Academy of Dermatology Meeting [Booth #1343] and will be forthcoming in the March issue of Journal of Clinical and Aesthetic Dermatology. Zoe Diana Draelos, MD, FAAD and Giuseppe Valacchi, PhD will present on "Reversing Glycation and Supporting Skin Quality with BioRewind Skin Health Dietary Supplement" at the L'Oréal R&I Theatre, Saturday March 8, 2:50 – 3:15pm. BioRewind is designed to be incorporated into an individual's daily routine."The process and impact differs dramatically from typical topical treatments on the market because it works from the inside-out," said Dr. Vivian Bucay, Bucay Center for Dermatology & Aesthetics. "This rosemary-based product is free of gluten, colorants, and dyes. My patients are excited to see results within just a few months by simply adding this into their existing skinbetter® routine." "This breakthrough formula is a game changer for skinbetter science and for our industry," said Christian Bouchard, President Medical Aesthetic Skincare, North America, L'Oréal. "By targeting glycation, BioRewind enhances the skin's appearance and is an invaluable tool for dermatologists aiming to offer comprehensive solutions to their patients." To learn more about BioRewind™ or find an authorized provider, visit About skinbetter science ®skinbetter science was formed in 2016 to establish a new biotech-based approach to skincare, built on three pillars: science, care and results. The team is committed to a technology pipeline of scientific innovation across multiple skincare categories, rigorous clinical substantiation of safety and efficacy of its products, as well as partnership with dermatologists, plastic surgeons, and other healthcare professionals in the aesthetic medical community in order to deliver best-in-class skincare solutions to their patients. skinbetter science is available exclusively through the leading dermatology, plastic surgery and medical aesthetics practices nationwide. To find an authorized skinbetter science physician near you, please visit Media Contact: EvolveMKD skinbetter@ References Draelos ZD, Gueniche A, Yatskayer M, Nelson DB. A Single-center, Double-blinded, Randomized, Placebo-controlled Trial Evaluated the Safety and Efficacy of a Dietary Supplement Containing Rosemary Extract on Visible Facial Skin Quality. J Clin Aesthet Dermatol. 2025;18(3): In press. Guitto A, Pecorelli A, Draelos ZD, Gueniche A, Yatskayer M, Nelson DB. Reversing Oxinflammation Associated with Glycative Stress and Formation of Advanced Glycation Endproducts with a Dietary Supplement Containing Rosemary Extract. J Clin Aesthet Dermatol. 2025;18(3): In press. View original content to download multimedia: SOURCE skinbetter science Sign in to access your portfolio
