Latest news with #Langone
Business Insider
17-07-2025
- Business
- Business Insider
'…One of Our Best Presidents' Home Depot Stock (NYSE:HD) Slips as Co-Founder Praises Trump
It was not so long ago when home improvement stock Home Depot's (HD) co-founder expressed his distaste for President Trump's tariffs by using an expletive. But the last few months have made a difference for Ken Langone, as he declared himself '…sold on Trump.' That was not all Langone had to say about Trump, or even about politics in general. But it did little good for Home Depot stock as shares slipped fractionally in Wednesday afternoon's trading. Elevate Your Investing Strategy: Take advantage of TipRanks Premium at 50% off! Unlock powerful investing tools, advanced data, and expert analyst insights to help you invest with confidence. Make smarter investment decisions with TipRanks' Smart Investor Picks, delivered to your inbox every week. Langone declared that Trump has '…got a good shot at going down in history as one of our best presidents ever.' In fact, it is Trump's leadership that has Langone noting that he's '…never been more excited about the future of America,' and that, '…like it or not, this guy is getting things done.' Langone's biggest concern was that Trump would spend the next four years '…getting even,' but the last several months proved to be anything but about revenge. Langone had previously been a Trump supporter for the 2016–2020 term, but after the events of January 6, that was enough for Langone to throw his support behind then-President Biden. After Trump's win in the 2024 election, Langone also had unkind words for the massive tariffs aimed at Asian countries. Cuomo For Mayor? Langone did not stop there. He also weighed in on the New York City mayoral race, noting that the person best-positioned to beat Democratic candidate Zohran Mamdani is Andrew Cuomo. Cuomo, who decided to run as an Independent after losing to Mamdani in the primary, actually got a donation from Langone via a superPAC backing Cuomo. Cuomo noted that only 13% of New Yorkers actually voted in the Democrat primary, which opens up a lot of potential room for him to win. Langone, for his part, noted that Cuomo had a ' wakeup call ' from his losses in the primary, which could put him in a better position to rally and take the office from Mamdani. Is Home Depot a Good Long-Term Buy? Turning to Wall Street, analysts have a Strong Buy consensus rating on HD stock based on 18 Buys and six Holds assigned in the past three months, as indicated by the graphic below. After a 3.56% loss in its share price over the past year, the average HD price target of $430.44 per share implies 20.73% upside potential.
New York Post
16-07-2025
- Business
- New York Post
Billionaire GOP donor Ken Langone reverses course on Trump — just months after calling tariffs ‘bulls–t'
Billionaire GOP donor Ken Langone gushed about President Trump's success in the White House – a stunning reversal after calling his tariffs 'bulls–t' just a few months ago. Langone, co-founder of Home Depot and chairman of NYU Langone's board of trustees, said he had been worried that Trump would use his time in the Oval Office 'to engage in retribution.' 'I'm happy to say that I'm comfortable he's not doing that. He's acting presidential. I'm impressed with the people he's got around him,' like former Fed governor Kevin Warsh, Langone told CNBC's 'Squawk Box' Tuesday. 3 Ken Langone reversed course on President Trump during his appearance on CNBC's 'Squawk Box' Tuesday. CNBC The billionaire in April slammed the president's tariffs as 'bulls–t' during an interview with the Financial Times – which has left Trump 'a little pissed off at me,' Langone said Tuesday. He said he had been worried that Trump's levies could reheat inflation and raise the budget deficit. But he now believes the 'big, beautiful' GOP bill will 'trigger significant economic growth, that we might see tax revenues going up from the profitability.' In April, Trump's harsh 'Liberation Day' taxes spooked investors and caused a massive stock sell-off. But in recent days, markets have largely shrugged off the latest tariff threats, remaining near all-time highs even as the president has threatened duties as high as 50% on many nations. Wall Street has been able to withstand the latest headlines as investors bank on tariff rates coming down during negotiations, or Trump backing off the initial rates. 'Like it or not, this guy's getting things done,' Langone said of Trump. 3 President Trump in the East Room of the White House on Wednesday. AP 'If I told you how bullish I was…I have never been more excited about the future of America than I am right now, right this minute.' He noted that Trump's strike on Iranian nuclear facilities acts as a symbol 'that America's here and when our interests are at risk we're going to do something about it.' Langone on Tuesday also shared his concerns over a rise in antisemitism, particularly among young Americans, as he tore into Zohran Mamdani, the 33-year-old socialist who won the Democratic primary for New York City mayor. 'I'm very vocal about it because so much in my life has revolved around Jews, all the good – doctors, friends, business partners, you name it,' Langone said. 3 Zohran Mamdani speaks during a press conference in July celebrating his primary victory. AFP via Getty Images 'I don't even understand the Jews sometimes. Thirty percent of Jewish voters voted for this guy [Mamdani] last week in New York. After what he said? I mean, give me a break.' Mamdani had refused to condemn the phrase 'globalize the intifada,' which has been seen as a call to violence against Jews, during the Democratic primary race. When pressed by Big Apple business leaders during a meeting Tuesday, Mamdani said he would not use the anti-Israel phrase and would 'discourage' others from doing so, according to attendees.
Daily Mail
10-07-2025
- Health
- Daily Mail
Compound in common over-the-counter supplement gives little boy, 8, the ability to walk again
A compound in a common over-the-counter supplement has given an eight-year-old the ability to walk again, in what has been called a 'dream come true'. The eight-year-old, who was not named, used to be the fastest runner in his class and an avid soccer player, regularly enjoying games with friends. But in August 2023, he started to struggle to walk — and within three months was limping, suffering frequent falls and needing a wheelchair. His parents rushed him to doctors, where physicians at NYU Langone diagnosed him with a genetic condition called HPDL deficiency. The disease is rare — with only 90 recorded cases since it was discovered in 2022 — and inhibits the body's ability to make enough of an enzyme called coenzyme Q10 (CoQ10), a compound that plays a vital role in giving cells energy. Taking CoQ10 supplements, available over-the-counter for around 20 cents per pill, can help, but they aren't enough to fuel cells in the brain because the enzyme is too large to cross the blood-brain barrier. Without enough of the enzyme in the brain, sufferers struggle to walk or control their muscles and are at risk of suffering from seizures. So, rather than simply give the little boy a supplement, his doctors said: 'We figured, why not give the cell the building blocks so that the cell can make it itself?' The 'building block' of CoQ10 is called 4-HB and is thin enough to cross the blood-brain barrier. Doctors were able to put this in a powder, which the boy took dissolved in a solution of water. His parents, speaking to STAT News on the condition of anonymity, said: 'Our son's condition dramatically changed in a short period. 'He went from being the fastest runner in his class and an avid soccer player to struggling just to walk, often limping and experiencing frequent falls'. 'It was one of the hardest decisions we've ever made [to try the experimental treatment], but doing nothing felt riskier. We saw how quickly our son was declining and knew we had to act. 'After speaking with doctors and doing our research, we got hope and confidence to step into the unknown.' Within a month of receiving the treatment in November 2023, he was smiling and walking again — completing nearly a mile-long hike across New York City's Central Park. He now regularly enjoys long hikes and sports and has celebrated two birthdays since. The case was revealed in the journal Nature, with researchers now saying they hope it can be used to help others. HPDL deficiency occurs when someone inherits two mutated versions of the human 4-hydroxyphenylpyruvate dioxygenase-like (HPDL) gene, which is used to make the CoQ10 enzyme. In some cases, the condition is very severe and strikes at an early age, causing significant cognitive delays and seizures. In these cases, researchers say patients often do not live beyond 18 months. But it can also strike at later stages in childhood and adolescence, leading otherwise healthy children to suffer muscle weakness and stiffness in the legs. Doctors have linked the condition to abnormal activity in the cerebral cortex — the outermost layer of the brain — which is involved in thought and muscle movement. In this case, the child reportedly suffered no symptoms until he turned eight years old — although doctors said it was likely that there were warning signs. The little boy was initially started on CoQ10 supplements before doctors suggested to the family that he try 4-HB - which is not approved by the FDA. His use of the supplements was then discontinued. Over the first 30 days, he drank the supplement in a 600ml solution, equivalent to nearly three glasses of water, which often led him to throw up afterward. This was then reduced to a 300ml solution, or just over one glass of water. The FDA has not approved CoQ10 or 4-HB as a treatment for any specific disease or condition, although CoQ10 is available as an over-the-counter supplement. The supplement is often recommended to boost energy and fight feelings of fatigue. Doctors say it can also provide support to people with conditions like congestive heart failure and migraines. 4-HB was initially tested on mice in a 2021 study that had HPDL deficiency, with researchers finding it restored the rodents' ability to walk. Its use in the eight-year-old was the first time it's been used for this condition in humans. '[CoQ10] is safe. It's reasonably effective at treating symptoms outside of the brain, but almost completely ineffective at treating symptoms within the brain, because it doesn't get through the blood-brain barrier,' Michael Pacold, an associate professor of radiation oncology at NYU Langone and one of the study authors, told STAT. The suggestion to use the 4-HB building block in the little boy was consented by the parents, the boy and the FDA — which approved its use as a single patient investigational drug, meaning the doctors could use an unapproved drug or substance for a specific patient to treat a specific condition. Based on its success, scientists are calling it a breakthrough in medicine. 'We all dream of this as scientists. And every morning I pinch myself … is this really a dream?' said Pacold. Dr Navdeep Chandel, a medicine expert at Northwestern University who was not involved in the research, added: 'That is basic science is translating into clinical medicine, a dream come true. '[But] here's somebody who took a very basic biochemical approach, and they found the enzyme, and they found what the enzyme does, and they gave that enzyme to people who had genetic mutations. And it made a difference.' Now, Pacold and his team are working on a larger study to test the approach on more children.
Yahoo
14-06-2025
- Health
- Yahoo
4 grocery store items colon cancer doctors avoid — and 3 they love
Diet isn't the only factor that contributes to colon cancer, but it often plays a role. Some of the clearest links have been drawn to sugar and red meat. Experts love coffee and cruciferous greens with anti-inflammatory properties. One of the most common questions that doctors treating colon cancer get is: "What else can I do?" Since colon cancer starts in the digestive tract, the food we put in our bodies is — rightly or wrongly — one of the first places people look, wondering: Is there some food I can eat that will help fight cancer, or some cancer-causing thing I should eliminate from my diet, stat? The truth is that how cancer emerges inside a body is quite complex. There isn't usually one single thing a person can do to stop it. While attending the world's biggest cancer conference earlier this month, I figured I'd cut through some of the noise out there and ask top colon cancer doctors directly what they generally recommend. Dr. Paul Oberstein, a medical oncologist at NYU Langone who specializes in gastrointestinal cancers, says his patients are often hunting for a winning superfood that can combat colon cancer. He fields questions routinely about the merits of avocados, pine nuts, and other items. Could adding those single items to the grocery cart help? While he says he's "doubtful" any single food can really make the difference in cancer recurrence, there are a few well-trodden truths doctors live by. These are backed by reams of study data from around the world. We still can't say for sure whether there's one specific diet that is best to combat cancer, and especially one diet that's best for you in particular. Plus, people with seemingly "clean" diets do get digestive cancers, even in their 30s and 40s. That being said, these four foods are consistently included in diets that seem to lead to cancer diagnoses later on, so oncologists warn against them. Sorry to everyone firing up the grill this summer! Study after study suggests that there really is something about red meat (and especially processed meats like hot dogs and deli cuts) that does the kind of DNA damage that can lead to colon cancer. Oberstein says patients often want to get prescriptive about it: Can I have red meat once a week? Twice a month? He's not really comfortable getting that granular with his advice, based on the data available. "We just don't have the quantification and the confidence to say it's either for sure going to help, or you can't have it ever," he told Business Insider. Dietician Lindsey Wohlford from MD Anderson Cancer Center created a chart in 2016 that recommends eating no more than two softballs' worth (18 oz.) of red meat per week. It's common knowledge in the medical community that over-consumption of sugar-sweetened beverages — including fruit juices, flavored coffees, and soda — can sharply up a person's risk of all kinds of diseases, from diabetes to colon cancer. Sugary drinks are more potent than sweet foods because liquid sugar is absorbed very fast — sometimes too fast. It can saturate the small intestine, spilling excess sugar into the colon. There's also evidence from animal studies that excess fructose — abundant in sugar and high fructose corn syrup — can escalate tumor growth. The latest research on young colon cancer also suggests that young people who report eating more sugary foods tend to have a higher risk of developing late-stage colon cancer. Dr. Andrea Cercek, co-director of the Center for Young Onset Colorectal Cancer at Memorial Sloan Kettering, is leading this research. She said it's not exactly a new idea that sugar can drive cancer growth. "There's even data in animal models that fructose can lead to polyps," Cercek told BI. Her latest find opens up new questions about what might be prompting more aggressive cases of young colon cancer. "Is sugar maybe somehow driving and accelerating this process?" Cercek asked. In a very basic sense, alcohol is just fermented sugar, and it seems to carry a lot of the same cancer risks. Additionally, our liver breaks down alcohol into acetaldehyde, a known cancer-causing chemical that can damage DNA. Finally, alcohol dampens nutrient absorption and can kill off good bacteria in your gut. In study after study, alcohol consumption is linked to more colon cancer diagnoses, and in general the more you drink, the greater your risk. Evidence suggests there might be something especially harmful about binge drinking or drinking on an empty stomach, when it comes to colon cancer. Most cancer doctors are not going to insist you can't enjoy a glass of wine or beer now and then, but they would probably say it's best to have it with a meal. If you're feeling hopeless now, buck up! There are a few tried-and-true items cancer doctors recommend adding to your shopping cart. Leafy salad greens are rich in all kinds of nutrients that are great at fighting off cancer, like folate and fiber. A special shout-out should go to the cruciferous green veggies like broccoli, Brussels sprouts, and kale, which are called "brassicas." They harbor bioactive compounds which are released when we chew them that have anti-inflammatory and anti-cancer effects. Fiber has a reputation for being great at keeping folks full and regular. But that's not all that it does. It also picks up debris in your gut, helping clear out the junk, and dropping off good guy bacteria. That's why Dr. Pashtoon Kasi, a medical oncologist at City of Hope who specializes in GI cancers, said it's "not just fiber for fiber's sake." He says it's underappreciated how fiber is "ameliorating or modulating the microbiome" in ways that may help prevent cancer in the long run. "Coffee comes up in every study," Oberstein said. This is great news for him personally, because he runs on the stuff. (But he says you don't need to feel pressured to start drinking coffee if you don't enjoy it.) There seems to be something deeply beneficial about the anti-inflammatory properties of coffee. Studies show that coffee isn't just good at preventing colon cancer (in one study, coffee drinkers had roughly 26% lower odds of contracting colon cancer) — people with colon cancer diagnoses who drink several cups of coffee a day also lower their odds of death. If you're looking for more widespread dietary advice, the National Comprehensive Cancer Care network guidelines for colon cancer patients recommend sticking to a "low glycemic load" diet, which means choosing more foods that are slow to digest and pack a fiber-rich punch. Low-glycemic foods include all kinds of fruits, veggies, nuts, beans, and whole grains. Dr. Kimmie Ng, a medical oncologist at Dana-Farber, where she is the founding director of the young-onset colorectal cancer center, says her recommendations fit this basic framework: "A diet less in red meat and processed foods and more in healthy proteins and fruits and vegetables is generally what we recommend," she told BI. "We know that that's typically anti-inflammatory and just healthier overall for a variety of chronic diseases, including cancer." Read the original article on Business Insider
New York Times
29-04-2025
- Health
- New York Times
A Lawmaker Blasted a Hospital's Super Bowl Ad. Then He Changed His Tune.
The 30-second television advertisement showed star doctors from a top-notch Manhattan hospital clumsily playing football. From the sidelines, a former standout player for the Giants suggested they should stick to medicine. The ad promoting NYU Langone Health probably did not rank among this year's most memorable Super Bowl commercials. But it sure bothered one viewer: a North Carolina congressman. The lawmaker promptly sent NYU Langone's chief executive a stern letter, noting that the hospital benefits from federal funds. 'I write today with questions about your stewardship of this money, including our serious concern about your decision to purchase a 30-second advertisement — estimated to cost $8 million — during Super Bowl LIX,' Representative Greg Murphy, a Republican, wrote on Feb. 11. The letter contained a list of pointed questions about NYU Langone's finances. It is the sort of missive that congressional offices routinely write to gather information for lawmaking or hearings. NYU Langone is hardly the only New York hospital to spend money on a national advertising campaign, although a Super Bowl ad is unusual. Those commercials speak to the intense competition among the country's elite medical centers. The congressman's reaction illustrates that with the promise of being in the spotlight comes peril. But, it turns out, opinions can change. Eight days after he first contacted the hospital, Representative Murphy wrote a follow-up letter. And that letter could not have been more different. The congressman had gone from critic to booster. The second letter expressed enthusiastic admiration for NYU Langone's 'world class patient outcomes' and 'superb' metrics — such as fewer deaths and shorter hospital stays. 'America would be much healthier if all hospitals could report these excellent numbers,' he wrote. Representative Murphy's letter stated that he had been left 'all-the-more impressed' after recently speaking with NYU Langone's chief executive, Dr. Robert Grossman. The letter does not indicate whether Dr. Grossman and the congressman had a phone call or met in person. But just two days before Representative Murphy sent his second letter, a private jet had landed at the sleepy airport in Greenville, N.C., the state's 12th-largest city, where Representative Murphy lives. The Bombardier Global 5000 was registered to Invemed Securities, the parent company of Invemed Associates, the investment firm founded by Kenneth G. Langone, the billionaire benefactor of NYU Langone and the chairman of the hospital's board of directors. Mr. Langone, who is best known for cofounding Home Depot, has given hundreds of millions of dollars to NYU's hospital system. In return, his name appears on the hospital. And Mr. Langone's largess allows for free tuition at NYU Grossman School of Medicine. He is also a major Republican donor, contributing more than $500,000 since 2020 to the National Republican Congressional Committee, which works to elect Republicans to the House of Representatives. He has donated millions more to other Republican organizations, such as the Senate Leadership Fund, a super PAC. Records do not show campaign donations from Mr. Langone to Representative Murphy; there can be delays in reporting contributions. It is not clear who was on the plane. A spokesman for NYU Langone, Steve Ritea, declined to answer questions about the hospital's interactions with the congressman or his staff members. Mr. Ritea also declined to say whether Dr. Grossman, the hospital CEO, flew to see Representative Murphy. Mr. Langone did not respond to requests for comment. Representative Murphy's office also declined repeated interview requests on the topic. But his spokesman acknowledged that it might seem 'a little confusing' that the tone in Representative Murphy's letters to Dr. Grossman went from critical to admiring. His spokesman would not share any information about material Dr. Grossman provided or what led the congressman to turn so quickly from critic to booster. 'I don't have much to add,' the spokesman for the congressman, Alexander Crane, said. 'I'd certainly understand that, you know, from A to B to C might seem a little confusing, but basically they had a wonderful private conversation.' Representative Murphy is a urologist who still regularly treats patients in Greenville. Another doctor at the same office where the congressman sees patients, Dr. Jonathan Hamilton, said he did not know if Mr. Langone or Dr. Grossman came to Greenville to visit Representative Murphy. The incoming chairman of the county's Republican Party said he hadn't heard of any such visit either. The operations manager for the Pitt-Greenville Airport Authority, John Hanna, confirmed that an aircraft with a tail number matching Mr. Langone's private jet was 'here for a short duration.' Flight records, accessible through a company that tracks flight information, place that private jet on the ground at Pitt-Greenville Airport for more than two hours on the afternoon of Feb. 17, Presidents' Day. The plane had flown in from Boca Raton, Fla., and returned there afterward. It appears to have been the only time this year the plane went to Greenville. Two days later, Representative Murphy released a statement along with his second letter. 'I was left impressed and grateful for the work the institution is doing,' he said. Representative Murphy's first letter, on Feb. 11, had posed questions that went beyond how much the Super Bowl ad had cost and how NYU Langone had paid for it. The congressman also asked about the hospital's overseas investments and why it had sought a 'rural' designation that would have increased the subsidies it received. NYU Langone is on Manhattan's East Side, on land that hasn't been rural for two centuries. The letter sought information on whether the health system was exploiting legal loopholes to maximize profit. In his follow-up letter, on Feb. 19, Representative Murphy wrote that he considered all his 'questions thoroughly answered.' But his office has declined to provide those answers to the public.
