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A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities
A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

San Francisco Chronicle​

time3 days ago

  • Climate
  • San Francisco Chronicle​

A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

GENEVA (AP) — A small Alpine river dammed by a landslide that largely buried the Swiss village of Blatten is now flowing through the debris, and the level of a newly created lake that raised worries about potential new destruction has fallen, authorities said Saturday. A huge mass of rock, ice and mud from the Birch glacier thundered into the Lötschental valley in southern Switzerland on Wednesday, destroying much of the village. Buildings that weren't buried were submerged in a lake created by the small Lonza River, whose course was dammed by the mass of material. Authorities worried that water pooling above the mass of rock and ice could lead to risks of its own. Still, the regional government in Valais canton (state) said that the Lonza has been flowing through the full length of the debris since Friday. Geologist and regional official Raphaël Mayoraz said Saturday that the level of the lake has since gone down about 1 meter (3.3 feet). 'The speed at which this lake is emptying comes from the river eroding the deposit,' he said at a news conference. 'This erosion is relatively slow, but that's a good thing. If it is too fast, then there is instability in this channel, and that could lead to small slides of debris.' 'The Lonza appears to have found its way, but it too early to be able to give an all-clear,' said Matthias Bellwald, Blatten's mayor. The outlet of a dam downstream at Ferden, which is normally used to generate electricity, was opened partially on Friday evening to allow water to flow further down the valley and regulate the volume of water behind the dam. Authorities are still leaving open the possibility of evacuations further downstream if required, though the risk to other villages appears very low.

A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities
A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

Hamilton Spectator

time3 days ago

  • Climate
  • Hamilton Spectator

A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

GENEVA (AP) — A small Alpine river dammed by a landslide that largely buried the Swiss village of Blatten is now flowing through the debris, and the level of a newly created lake that raised worries about potential new destruction has fallen, authorities said Saturday. A huge mass of rock, ice and mud from the Birch glacier thundered into the Lötschental valley in southern Switzerland on Wednesday , destroying much of the village. Buildings that weren't buried were submerged in a lake created by the small Lonza River, whose course was dammed by the mass of material. Authorities worried that water pooling above the mass of rock and ice could lead to risks of its own. Still, the regional government in Valais canton (state) said that the Lonza has been flowing through the full length of the debris since Friday. Geologist and regional official Raphaël Mayoraz said Saturday that the level of the lake has since gone down about 1 meter (3.3 feet). 'The speed at which this lake is emptying comes from the river eroding the deposit,' he said at a news conference. 'This erosion is relatively slow, but that's a good thing. If it is too fast, then there is instability in this channel, and that could lead to small slides of debris.' 'The Lonza appears to have found its way, but it too early to be able to give an all-clear,' said Matthias Bellwald, Blatten's mayor. The outlet of a dam downstream at Ferden, which is normally used to generate electricity, was opened partially on Friday evening to allow water to flow further down the valley and regulate the volume of water behind the dam. Authorities are still leaving open the possibility of evacuations further downstream if required, though the risk to other villages appears very low. Days before most of the glacier collapsed, authorities had ordered the evacuation of about 300 people , as well as livestock, from Blatten. Switzerland's president said on Friday that the government was looking for ways to help the evacuees.

A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities
A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

Winnipeg Free Press

time3 days ago

  • Climate
  • Winnipeg Free Press

A river dammed by a huge Swiss landslide is flowing again. That's a relief to authorities

GENEVA (AP) — A small Alpine river dammed by a landslide that largely buried the Swiss village of Blatten is now flowing through the debris, and the level of a newly created lake that raised worries about potential new destruction has fallen, authorities said Saturday. A huge mass of rock, ice and mud from the Birch glacier thundered into the Lötschental valley in southern Switzerland on Wednesday, destroying much of the village. Buildings that weren't buried were submerged in a lake created by the small Lonza River, whose course was dammed by the mass of material. Authorities worried that water pooling above the mass of rock and ice could lead to risks of its own. Still, the regional government in Valais canton (state) said that the Lonza has been flowing through the full length of the debris since Friday. Geologist and regional official Raphaël Mayoraz said Saturday that the level of the lake has since gone down about 1 meter (3.3 feet). 'The speed at which this lake is emptying comes from the river eroding the deposit,' he said at a news conference. 'This erosion is relatively slow, but that's a good thing. If it is too fast, then there is instability in this channel, and that could lead to small slides of debris.' 'The Lonza appears to have found its way, but it too early to be able to give an all-clear,' said Matthias Bellwald, Blatten's mayor. Wednesdays A weekly look towards a post-pandemic future. The outlet of a dam downstream at Ferden, which is normally used to generate electricity, was opened partially on Friday evening to allow water to flow further down the valley and regulate the volume of water behind the dam. Authorities are still leaving open the possibility of evacuations further downstream if required, though the risk to other villages appears very low. Days before most of the glacier collapsed, authorities had ordered the evacuation of about 300 people, as well as livestock, from Blatten. Switzerland's president said on Friday that the government was looking for ways to help the evacuees.

Induced Pluripotent Stem Cell (iPSC) Industry Report 2025-2030: iPSCs Set to Redefine Clinical and Research Paradigms, iPSC Technology Drives Innovation in Regenerative Therapy
Induced Pluripotent Stem Cell (iPSC) Industry Report 2025-2030: iPSCs Set to Redefine Clinical and Research Paradigms, iPSC Technology Drives Innovation in Regenerative Therapy

Yahoo

time27-05-2025

  • Business
  • Yahoo

Induced Pluripotent Stem Cell (iPSC) Industry Report 2025-2030: iPSCs Set to Redefine Clinical and Research Paradigms, iPSC Technology Drives Innovation in Regenerative Therapy

Dublin, May 27, 2025 (GLOBE NEWSWIRE) -- The "Induced Pluripotent Stem Cell (iPSC) Industry Report - Market Size, Trends, & Forecasts, 2025" has been added to offering. The market for iPSC-derived products continues expanding with involvement from companies like Lonza, BD Biosciences, and Thermo Fisher Scientific, among others. Over 90 companies actively engage in this market, offering diverse products and technologies for research and therapeutic applications. Since discovering iPSCs 18 years ago, remarkable advancements have occurred. It saw its first human application in 2013, and now at least 155 clinical trials use iPSCs globally. iPSCs are being tested for various conditions, including Parkinson's disease, cancer immunotherapies with iNK cells, age-related macular degeneration, and Type 1 diabetes. This diversity underscores iPSCs' transformative potential in treating numerous diseases. Commercially, companies harness iPSC products for drug development, disease modeling, and toxicology testing. Notable players include FUJIFILM Cellular Dynamics International (FCDI), a leader in iPSC-derived human cell production, and ReproCELL, pioneering iPSC product commercialization. Europe also hosts major competitors like Evotec and Ncardia, specializing in drug screening and cardiac applications, respectively. The potential of iPSCs to redefine medicine and biotechnology is substantial. As iPSC applications evolve in disease modeling, drug discovery, and cell therapies, they drive innovation within healthcare and research, paving the way for transformative advancements. This comprehensive report outlines key players, strategic partnerships, and innovations propelling the sector. It details advancements in iPSC research, manufacturing, and clinical developments, alongside an analysis of the funding landscape. Projected market growth rates through 2030, categorized by application, technology, cell types, and geography, offer insights into iPSC industry's future. Current Commercialization Methods of iPSCs: Cellular Therapy: iPSCs are being explored for cell therapy applications to repair injuries or cure diseases by substituting damaged cells. Disease Modeling: Patient-specific iPSCs are differentiated into disease-specific cells, creating functional models for research. Drug Development: iPSCs deliver physiologically relevant cells for drug discovery, enhancing the efficacy of compound identification, target validation, and screening processes. Personalized Medicine: Integration with genome-editing technologies facilitates customized treatments by modifying iPSCs at the genetic level. Toxicology Testing: Screening iPSCs or derivatives to evaluate compound safety and efficacy reduces dependence on animal testing. Tissue Engineering: Culturing iPSCs on biocompatible scaffolds supports engineered tissue development for transplantation. Organoid Production: Self-organizing iPSCs form 3D organoids, facilitating organ study, disease modeling, and drug testing. Gene Editing: Techniques like CRISPR enable iPSC modifications for mutation correction, facilitating functional cell development for treatments. Research Tools: Extensive research applications include studying cellular processes and testing experimental therapies with iPSCs. Stem Cell Banking: iPSC repositories offer diverse cell types for research, allowing investigations into conditions using samples from various donors. Cultured Meat Production: iPSCs serve as cellular bases for lab-grown meat production, promoting sustainable alternatives. 3D Bioprinting: Differentiated iPSCs are used in bioinks for creating complex tissue structures via 3D bioprinting. Key Topics Covered: 1. REPORT OVERVIEW1.1 Statement of the Report1.2 Executive Summary 2. INTRODUCTION 3. CURRENT STATUS OF IPSC INDUSTRY3.1 Progress made in Autologous Cell Therapy using iPSCs3.2 Allogeneic iPSC-based Cell Therapies3.3 Share of iPSC-based Research within the Overall Stem Cell Industry3.4 Major Focus Areas of iPSC Companies3.5 Commercially Available iPSC-derived Cell Types3.6 Relative use of iPSC-derived Cell Types in Toxicology Testing Assays3.7 iPSC-derived Cell Types used in Clinical Trials3.8 Currently Available iPSC Technologies 4. HISTORY OF INDUCED PLURIPOTENT STEM CELLS (IPSCS)4.1 First iPSC Generation from Mouse Fibroblasts, 20064.2 First Human iPSC Generation, 20074.3 Creation of CiRA, 20104.4 First High-Throughput Screening using iPSCs, 20124.5 First iPSC Clinical Trial Approved in Japan, 20134.6 First iPSC-RPE Cell Sheet Transplantation for AMD, 20144.7 EBiSC Founded, 20144.8 First Clinical Trial using Allogeneic iPSCs for AMD, 20174.9 Clinical Trial for Parkinson's Disease using Allogeneic iPSCs, 20184.10 Commercial iPSC Plant SMaRT Established, 20184.11 First iPSC Therapy Center in Japan, 20194.12 First U.S.-based NIH-Sponsored Clinical Trial using iPSCs, 20194.13 Cynata Therapeutics' World's Largest Phase III Clinical Trial, 20204.14 Tools and Know-how to Manufacture iPSCs in Clinical Trials, 20214.15 Production of in-house iPSCs using Peripheral Blood Cells, 2022 5. RESEARCH PUBLICATIONS ON IPSCS5.1 Rapid Growth in iPSC Publications 6. IPSC: PATENT LANDSCAPE ANALYSIS6.1 iPSC Patent Applications by Jurisdiction6.2 iPSC Patent Applicants6.3 Inventors of iPSC Patents6.4 iPSC Patent Owners6.5 Legal Status of iPSC Patents 7. IPSC: CLINICAL TRIAL LANDSCAPE7.1 Number of iPSC Clinical Trials7.1 Recruitment Status of iPSC Clinical Trials7.3 iPSC Clinical Trials Stydy Designs7.4 Therapeutic & Non-Therapeutic iPSC Clinical Trials7.5 iPSC-based Trials by Phase of Study7.6 iPSC Clinical Trials by Funder Type7.7 Geographic Distribution of iPSC-based Clinical Trials7.8 Promising iPSC Product Candidates7.9 Companies having Preclinical iPSC Assets 8. M&A, COLLABORATIONS & FUNDING ACTIVITIES IN IPSC SECTOR8.1 Mergers and Acquisitions (M&A) Sector8.2 Partnership/Collaboration & Licensing Deals in iPSC Sector8.3 Venture Capital Funding in iPSC Sector 9. GENERATION OF INDUCED PLURIPOTENT STEM CELLS (IPSCS)9.1 OSKM Cocktail9.2 Pluripotency-Associated Transcription Factors and their Functions9.3 Delivery of Reprogramming Factors9.4 Genome Editing Technologies in iPSC Generation9.5 Available iPSC Lines and their applications 10. HUMAN IPSC BANKING10.1 Major Biobanks Storing iPSCs & iPSC Lines10.2 Cell Sources for iPSC Banks10.3 Reprogramming Methods in iPSC Banks10.4 Ownership and Investments made in iPSC Banks 11. BIOMEDICAL APPLICATIONS OF IPSCs11.1 iPSCs in Basic Research11.2 Applications of iPSCs in Drug Discovery11.3 Applications of iPSCs in Toxicology Studies11.4 Applications of iPSCs in Disease Modeling11.5 Applications of iPSCs in Cell-Based Therapies11.6 Other Novel Applications of iPSCs 12. MARKET ANALYSIS12.1 Global Market for iPSCs by Geography12.2 Global Market for iPSCs by Technology12.3 Global Market for iPSCs by Biomedical Application12.4 Global Market for iPSCs by Derived Cell Type12.5 Market Drivers12.6 Market Restraints 13. COMPANY PROFILES For more information about this report visit About is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends. CONTACT: CONTACT: Laura Wood,Senior Press Manager press@ For E.S.T Office Hours Call 1-917-300-0470 For U.S./ CAN Toll Free Call 1-800-526-8630 For GMT Office Hours Call +353-1-416-8900Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

Hi & Fi Asia-China 2025: Charting New Frontiers in Health and Food Innovation
Hi & Fi Asia-China 2025: Charting New Frontiers in Health and Food Innovation

Yahoo

time19-05-2025

  • Business
  • Yahoo

Hi & Fi Asia-China 2025: Charting New Frontiers in Health and Food Innovation

SHANGHAI, May 19, 2025 /PRNewswire/ -- Asia's most anticipated trade platform for health ingredients and food innovation, Hi & Fi Asia-China, returns with its landmark 2025 edition from June 24–26 at the National Exhibition and Convention Center (NECC) Shanghai, China. Uniting global leaders in food ingredients, nutraceuticals, and sustainable solutions. With the exhibitor list now live and exclusive activities announced, this flagship event will unmatched opportunities for sourcing, learning, and networking. 1. Global Exhibitors: Connect with Industry Pioneers Over 500 top-tier exhibitors will showcase cutting-edge solutions. Engage directly with suppliers driving trends in peptides, probiotics, botanical extracts, and sustainable processing Players: Ingredient Giants: Givaudan, Lonza, BGG, Synbio Tech — leaders in functional additives, enzymes, and bioactive compounds. Golden Omega, Vilof, Luhua Biomarine, Bloomage Biotechnology— pioneers in collagen, plant extracts, and marine biotechnology. 2. Featured Product Categories: Source Tomorrow's Solutions Today Explore different product zones spanning the entire food-health value chain. Top Categories: Functional Ingredients: Collagen, DHA/EPA, plant proteins, and probiotics for next-gen formulations. Natural & Clean Label: Botanical extracts, squalane, and herbal ingredients catering to clean-label demands. Processing Innovation: Enzymes, emulsifiers, and microencapsulated powders for enhanced bioavailability. 3. Expert-Led Bilingual Forums: Master Industry Trends Innovated Supplements and Sports Performance Enhancement ConferenceCo-host: ISSNKeynote: Drew Campbell (GPNi) and Dr. Johan Thuvander (NiHTEK) will decode performance-enhancing ingredients and e-commerce strategies. EPA and DHA Omega-3s: Market Trends and Industry DevelopmentsCo-host: GOEDKeynote: Ellen Schutt (GOED) and Casey Li (Pattern China) reveal e-commerce tactics and purity standards for omega-3 success. Regulation Forum: Navigating the New Era of Sustainable Trade Co-host: SolidaridadAgenda: Navigate EU deforest action regulations (EUDR) and Corporate Sustainability Due Diligence Directive (CSDDD), build compliant sustainable supply chains for ingredients. 4. Curated Tours: Dive into Niche Markets Embark on a transformative journey at Hi & Fi Asia-China! Join the Healthy Aging and Nutricosmetic Tour to uncover groundbreaking ingredients and formulations targeting the pillars of longevity and wellness. Silver Walk: Healthy Aging InnovationsPartner: Early DataFocus: Explore peptides for cognitive support and fermented ginseng for cellular vitality. Tailored for senior nutrition and longevity-focused brands. Beauty Walk: Nutricosmetic Revolution Partner: Innova Market Insights Focus: Discover ingredients like sodium hyaluronate for skin health and ergothioneine for UV protection. Perfect for beauty-from-within brands and R&D teams. 5. Attendee Benefits: Unlock Premium Perks Free Badge Includes: VIP lounge access and 2 free lunch coupons. 200-Yuan exhibitor catalogue and pre-show matchmaking. Free entry to CPHI China, Healthplex Expo / Natural & Nutraceutical Products China (HNC), and 2 co-located shows. Register Now: About Hi & Fi Asia-China:As Asia's premier hub for food and health ingredients, Hi & Fi Asia-China bridges global suppliers with China's huge health market. See you in Shanghai – where innovation meets opportunity! Contact:Sini BaiEmail: +8602133392212 View original content: SOURCE Hi & Fi Asia-China Sign in to access your portfolio

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