25-05-2025
CIMAP's cream for psoriasis set to take market by storm
Lucknow: CSIR Central Institute of Medicinal and Aromatic Plants (CIMAP) has developed a new herbal solution for psoriasis, a chronic autoimmune skin disease that causes thick, red, scaly patches (plaques) on the skin.
The scientific institute introduced PsoriaCIM, a new lavender-based, expertly crafted cream formulation designed to treat the skin disease safely and effectively.
While a patent is pending, CIMAP has successfully transferred its technology to a Lucknow-based private firm for commercial production.
"The herbal formulation has been created solely for psoriasis, a very common disease which affects around 2–3% of the world's population, including a notable burden in India (0.44% to 2.8%).
It is also associated with cardiovascular, metabolic, and psychiatric conditions," said chief investigator and senior principal scientist NP Yadav.
"The available treatments for psoriasis contain corticosteroids, which have significant side effects. Our product is a unique combination of phytomolecules obtained from lavender oil, which is safe and as effective as steroid-based treatment available in the market," said chief investigator and senior principal scientist NP Yadav.
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"It has shown remarkable performance in preclinical models, demonstrating significant efficacy in mitigating psoriatic inflammation, and was found to match the effects of 0.1% mometasone cream, a widely used steroid-based therapy," the scientist said.
He further explained that this breakthrough research was launched after extensive in-vitro and in-vivo studies in rodent animals that revealed that the formulation demonstrates the synergistic effect of the combination, reducing the Psoriasis Area and Severity Index (PASI) scores significantly.
To ensure its safety, skin irritation tests were conducted along with repeated dose dermal toxicity studies, confirming the formulation's skin-friendly and non-irritant nature.
"PsoriaCIM is a scientifically validated formulation, developed through years of rigorous research that bridges the gap between traditional herbal wisdom and modern scientific innovation.
"For over a decade, Yadav and his team dedicated themselves to developing a nature-inspired solution for psoriasis," said CSIR CIMAP director Prabodh Kumar Trivedi.
CIMAP's head of business development, RK Srivastava, said that technology transfer of PsoriaCIM marks a significant step forward in harnessing the power of medicinal and aromatic plants.