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Time of India
04-05-2025
- Health
- Time of India
Long Covid affects millions: Scientists begin trial for potential breakthrough treatment
Long Covid remains a major concern for millions worldwide. After an infection caused by the SARS-CoV-2 virus, many individuals continue to experience a wide range of symptoms that disrupt their daily lives. These persistent issues, which can include fatigue, brain fog, and breathing difficulties, are collectively known as Long Covid. The condition is still not fully understood, and it presents with different symptoms. As researchers search for effective treatments, a new clinical trial has emerged, offering hope for those affected. Scientists launch clinical trial for Sipavibart A team of researchers from Nova Southeastern University (NSU) in the United States, in partnership with the Schmidt Initiative for Long Covid (SILC), has launched a clinical trial to evaluate the effectiveness of sipavibart. This long-acting monoclonal antibody, developed by AstraZeneca, has already been approved in countries like Japan and the EU for preventing COVID-19 before exposure. However, this trial is the first time it will be tested for its ability to ease Long Covid symptoms . by Taboola by Taboola Sponsored Links Sponsored Links Promoted Links Promoted Links You May Like Google Brain Co-Founder Andrew Ng, Recommends: Read These 5 Books And Turn Your Life Around Blinkist: Andrew Ng's Reading List Undo The clinical trial has already enrolled 100 patients and aims to collect data over the next few years to see if sipavibart can help reduce the many symptoms of Long Covid. Approved by the Food and Drug Administration (FDA) earlier this year, researchers are hopeful this treatment could offer significant relief to those affected by the condition. A complex and confusing condition Long Covid is a condition that continues to puzzle both patients and medical professionals. With over 200 reported symptoms, the effects of the illness can vary greatly from person to person. While some people experience only mild symptoms that come and go, others face severe, long-lasting challenges that can severely impact their quality of life. 'Like many multi-symptom, post-viral conditions, Long Covid is incredibly complicated and thus little understood,' explained Dr. Nancy Klimas, director of the Institute for Neuro-Immune Medicine at NSU. 'Finding a treatment will be life-changing for patients suffering from the myriad symptoms of Long Covid.' The complexity of Long Covid has made it hard to find a treatment that works for everyone. This is why the trial of sipavibart is considered an important step, as it may offer a much-needed solution for those affected. Sipavibart: A promising treatment option Sipavibart's potential as a treatment for Long Covid is still being tested, but there is increasing hope. The monoclonal antibody works by targeting and neutralizing the virus, and researchers believe it could help patients recover more quickly and with fewer long-term health problems. While sipavibart is already approved for Covid-19 prevention, this trial explores its new use to treat the ongoing symptoms of Long Covid. Dr. John Redd, CEO of SILC, pointed out the scale of the problem: 'Long Covid affects at least 65 million people worldwide, and with more than 200 symptoms, the health impacts of the disease can be debilitating. This trial represents our overall commitment to addressing the most pressing health challenges of our time.' A collaborative effort This trial is more than just a study; it's a team effort to address one of the biggest health issues today. With millions suffering from a wide range of symptoms, finding a treatment for Long Covid is critical. Researchers are hopeful that sipavibart could help manage these symptoms and give patients a chance to get back to normal life. 'We're leveraging our research expertise to potentially transform treatment options for millions suffering from Long Covid, advance knowledge, and improve patient outcomes through innovative clinical research,' said Dr. Ken Dawson-Scully, NSU's senior vice president for research and associate provost. Masterclass for Students. Upskill Young Ones Today!– Join Now


India.com
04-05-2025
- Health
- India.com
Scientists Launch Trial To Test Long-Acting Antibody For Long Covid
New Delhi: US scientists are undertaking a clinical trial to decode the efficacy of a long-acting antibody against Long Covid -- a condition that affects at least 65 million people worldwide. Long Covid affects people after an infection caused by the SARS-CoV-2 virus. The condition not properly defined yet presents with more than 200 symptoms. The team from the Nova Southeastern University (NSU) and the Schmidt Initiative for Long Covid (SILC) announced that a clinical trial is underway to assess the effectiveness and safety of sipavibart -- a long-acting monoclonal antibody designed by British drugmaker AstraZeneca's to protect the condition. The team enrolled 100 patients in the multi-year research, reviewed and cleared by the FDA earlier this year. It aims to improve patients Long Covid symptoms and restore them to full health. 'Like many multi-symptom, post-viral conditions, Long Covid is incredibly complicated and thus little understood,' said Nancy Klimas, director of the Institute for Neuro-lmmune Medicine at NSU. 'Finding a treatment will be life-changing for patients suffering from the myriad symptoms of Long Covid,' she added. The study will test whether the monoclonal antibody sipavibart -- approved for the pre-exposure prophylaxis (prevention) of Covid-19 in Japan and the EU -- is effective in treating Long Covid. The trial is one of three Long Covid treatment trials expected to begin in 2025. 'Long Covid affects at least 65 million people worldwide, and with more than 200 symptoms, the health impacts of the disease can be debilitating,' said Dr. John Redd, CEO of SILC. 'This trial represents our overall commitment to addressing the most pressing health challenges of our time. We're leveraging our research expertise to potentially transform treatment options for millions suffering from Long Covid, advance knowledge, and improve patient outcomes through innovative clinical research,' added Dr. Ken Dawson-Scully, NSU's senior vice president for research and associate provost.


Hans India
03-05-2025
- Health
- Hans India
US scientists to explore potential of antibody against Long Covid
New Delhi: US scientists are undertaking a clinical trial to decode the efficacy of a long-acting antibody against Long Covid -- a condition that affects at least 65 million people worldwide. Long Covid affects people after an infection caused by the SARS-CoV-2 virus. The condition not properly defined yet presents with more than 200 symptoms. The team from the Nova Southeastern University (NSU) and the Schmidt Initiative for Long Covid (SILC) announced that a clinical trial is underway to assess the effectiveness and safety of sipavibart -- a long-acting monoclonal antibody designed by British drugmaker AstraZeneca's to protect the condition. The team enrolled 100 patients in the multi-year research, reviewed and cleared by the FDA earlier this year. It aims to improve patients Long Covid symptoms and restore them to full health. 'Like many multi-symptom, post-viral conditions, Long Covid is incredibly complicated and thus little understood,' said Nancy Klimas, director of the Institute for Neuro-lmmune Medicine at NSU. 'Finding a treatment will be life-changing for patients suffering from the myriad symptoms of Long Covid,' she added. The study will test whether the monoclonal antibody sipavibart -- approved for the pre-exposure prophylaxis (prevention) of Covid-19 in Japan and the EU -- is effective in treating Long Covid. The trial is one of three Long Covid treatment trials expected to begin in 2025. 'Long Covid affects at least 65 million people worldwide, and with more than 200 symptoms, the health impacts of the disease can be debilitating,' said Dr. John Redd, CEO of SILC. 'This trial represents our overall commitment to addressing the most pressing health challenges of our time. We're leveraging our research expertise to potentially transform treatment options for millions suffering from Long Covid, advance knowledge, and improve patient outcomes through innovative clinical research,' added Dr. Ken Dawson-Scully, NSU's senior vice president for research and associate provost.