Latest news with #Novocaine

Business Insider
16-05-2025
- Entertainment
- Business Insider
15 movies and shows to stream this weekend, from season 2 of 'The Secret Lives of Mormon Wives' to a new sci-fi thriller
Jack Quaid plays an average guy with an uncanny ability to not feel pain in "Novocaine." Jack Quaid, known for playing an unlikely vigilante in the superhero satire series " The Boys," portrays a different kind of action star in "Novocaine." In the 2025 film, Quaid stars as Nathan Caine, an introverted everyman who works at a trust credit union. When his coworker, whom he has a crush on, gets kidnapped, Nathan uses his inability to feel pain to fight and try to rescue her. The '70s-set drama series "Duster" follows a getaway driver and a rookie FBI agent. "Lost" star Josh Holloway plays Jim, a getaway car driver who teams up with Nina (Rachel Hilson), the first Black female FBI agent, to take down a crime syndicate in the Southwest. The eight-episode series is co-created by J.J. Abrams, and new episodes release weekly, leading to the finale on July 3. "Better Man" offers a fresh take on the typical biopic. See Adrien Brody's Oscar-winning performance in "The Brutalist." If the lengthy runtime and intermission deterred you from seeing " The Brutalist" in theaters, you can now watch the film at home. The movie stars Adrien Brody as László Tóth, a Hungarian-Jewish Holocaust survivor and accomplished architect who immigrates to America post-WWII to rebuild his life. For a coming-of-age comedy series, check out "Overcompensating." Actor and comedian Benito Skinner, known for his internet persona Benny Drama, brings his humor to Hollywood as the creator and writer of Prime Video's raunchy college series "Overcompensating." In the show, he plays Benny Scanlon, a closeted freshman trying to keep up appearances while also figuring out who he really is. The eight-episode first season dropped all at once this week, featuring cameos from celebrities like Charli XCX and Megan Fox. Watch "Matteo Lane: The Al Dente Special" for more laughs. "Andor" came to an end this week. Alexander Skarsgård stars as a rogue robot with free will in "Murderbot." The Apple TV+ series adaptation of Martha Wells' bestselling book series "The Murderbot Diaries" fuses comedy and thrills as it follows a security construct with an artificial body. After hacking his system and gaining free will, Muderbot (Alexander Skarsgård) tries to maintain his cover while on assignment with a team of researchers when really, he'd rather just watch soap operas. Season two of "The Secret Lives of Mormon Wives" brings more drama. The new season kicks off with the surprise arrival of Miranda McWhorter, the former best friend of star Taylor Frankie Paul and one of the original MomTok members. After distancing herself from the group amid the swinging scandal, McWhorter is back to repair her friendships and possibly rejoin MomTok. All 10 episodes are streaming now. "Untold: The Liver King" chronicles the rise and fall of a health influencer. Remember the raw organ-eating influencer who touted an "ancestral lifestyle" and unconventional health practices? Netflix's new documentary "Untold: The Liver King" unpacks the life of the disgraced internet star known as Liver King, aka Brian Johnson, and the steroid scandal that caused backlash. True crime fans can check out "Fred and Rose West: A British Horror Story." The three-episode limited series tells the story of married couple Fred and Rose West, notorious UK serial killers who committed horrific crimes against their own kids and other young women and children. Season seven of the scripted sports drama series "All American" is now streaming. For unscripted sports, watch the new season of "Welcome to Wrexham." Season four of "Welcome to Wrexham" continues to document the journey of Wrexham AFC, the oldest English football club in Wales that made waves when it was purchased by Ryan Reynolds and Rob McElhenney a few years ago. Or "Vini Jr." Season 50 of "Saturday Night Live" ends this weekend.


Express Tribune
14-05-2025
- Entertainment
- Express Tribune
‘Novocaine' now streaming on Paramount+ with 81% Rotten Tomatoes score
Jack Quaid's action-thriller Novocaine is now officially streaming on Paramount+, following a successful theatrical run and strong critical reception. The film, which holds an 81% critic score and an 85% audience score on Rotten Tomatoes, was directed by Dan Berk and Robert Olsen from a script by Lars Jacobson. Novocaine stars Quaid as Nathan Caine, a mild-mannered bank employee who can't feel pain due to a rare medical condition. When his co-worker and love interest Sherry (played by Amber Midthunder) is kidnapped during a bank heist, Caine embarks on a relentless, pain-defying mission to rescue her. The cast also includes Ray Nicholson (Smile 2), Jacob Batalon (Spider-Man: No Way Home), and Matt Walsh (Veep). Originally released on March 14, Novocaine topped the box office during its opening weekend, earning $8.8 million. Despite modest earnings, the film became one of the lowest-grossing No. 1 openers post-2020, ultimately reaching $34.2 million globally against an $18 million budget. Quaid celebrated the film's streaming debut with behind-the-scenes photos on Instagram, calling Novocaine 'a brutally fun ride' and encouraging fans to tune in on Paramount+. The Boys star continues to have a busy year. His sci-fi film Companion is also a streaming hit on Max, with a 93% critic score. Additionally, Quaid stars in Neighborhood Watch, now available digitally, alongside Jeffrey Dean Morgan and Malin Akerman. Novocaine adds to Jack Quaid's growing list of critically praised roles, solidifying his status as one of 2025's most in-demand action and thriller stars.


India Today
29-04-2025
- Entertainment
- India Today
10 much-awaited Hollywood releases of 2025
10 much-awaited Hollywood releases of 2025 Apr 25, 2025 After Sinners, Novocaine and Minecraft, here is a list of 10 most-anticipated Hollywood films of 2025. Check it out. Marvel's misfit squad of anti-heroes bands together for a gritty, action-packed mission that blurs the line between good and evil. Thunderbolts Credit: Marvel Studios Ethan Hunt returns for one last, high-octane globe-trotting adventure to close out the legendary spy saga. Mission: Impossible – The Final Reckoning Credit: Instagram/Tom Cruise Starring Ana de Armas in the John Wick spinoff film, it arrives this summer, with Keanu Reeves appearing as the titular character. Ballerina Credit: IMDb Pixar's newest heartwarming tale follows a boy who's mistakenly chosen as Earth's ambassador by aliens, leading to an out-of-this-world journey. Elio Credit: Pixar The beloved animated franchise gets a live-action makeover, reigniting the magical bond between Hiccup and Toothless. How To Train Your Dragon (Live Action) Credit: Universal Brad Pitt gears up as a veteran driver mentoring a rookie in this adrenaline-fueled, Formula 1 racing drama produced by Lewis Hamilton. F1 Dinosaurs return with a vengeance in this rebooted chapter that promises fresh thrills and a whole new era of prehistoric chaos. It stars Jonathan Bailey, Scarlett Johansson and Mahershala Ali. Jurassic World: Rebirth James Gunn reimagines the Man of Steel with a fresh start, blending classic heroism with modern-day relevance in the DC Universe. Superman Credit: DC Studios Marvel's first family finally enters the MCU with a bold origin story that promises cosmic stakes and emotional depth. Fantastic Four: The Four Steps Credit: Marvel The digital frontier expands with Jared Leto entering the Grid in a visually stunning continuation of the Tron legacy. Tron: Ares Credit: Disney

Yahoo
23-04-2025
- Yahoo
Genovese gangster, 95, who once plotted to kill John Gotti, gets compassionate release
A 95-year-old mobster who once plotted to whack John Gotti will be allowed to die at home with his family, after a federal judge granted the ailing wiseguy compassionate release. Louis 'Bobby' Manna — who rose to the rank of consigliere, the number three spot in the Genovese Crime Family, before his 1988 arrest on racketeering charges — has served about 36 years of his 80-year federal racketeering sentence. He was denied release back in 2020. On April 16, New Jersey District Court Judge Robert Kirsch granted Manna compassionate release under the First Step Act, stating that his grim health prognosis and his efforts at rehabilitation behind bars tipped the scales in his favor. 'Mr. Manna's well-chronicled severe health problems undoubtedly establish 'extraordinary and compelling reasons' for compassionate release,' Kirsch wrote. Those problems include a stroke, high risk Stage II metastatic lung cancer, chronic kidney disease and a recurring infection. He was placed in a 'Fall Watch' room, under 24-hour medical observation, at the Federal Medical Center prison in Rochester, in September. Manna will be placed on five years of supervised release, on 24-hour house arrest with electronic monitoring, and won't be allowed to communicate with anyone but his custodians and probation officials. 'The court is satisfied that these conditions, which essentially render Mr. Manna a dying prisoner in his custodians' home, reflect the seriousness of his crimes and are just punishment for a man at the very last stage of life,' Kirsch said. Manna, whose criminal history dates back to at least 1952, oversaw the 'Manna Faction' of the Genovese family, and answered at times to underboss 'Fat' Tony Salerno and boss Vincent 'Chin' Gigante, He was admired in organized crime circles in his heyday for never turning government informant even as he faced down prison terms, and once refused a shot of Novocaine for a prison tooth extradition because he was afraid he'd break omerta. Manna was convicted of plotting to kill rival Gambino family boss John Gotti and his brother Gene back in the late '80s. He was caught discussing the plan on a FBI bug planted in a Hoboken restaurant: 'Remember I told you it was a big hit? John Gotti.' The feds warned Gotti about the plot, and the attempt never got off the ground. He also ordered the August 1987 rub-out of Irwin Schiff, an FBI informant who was also skimming cash from the Genovese family. A masked gunman, selected by Manna, walked out of the bathroom of the Bravo Sergio Restaurant on the Upper East Side and shot Schiff twice in the head. Judge Maryanne Trump Barry, President Trump's late sister, handed down Manna's sentence in 1989. Trump signed the First Step Act, which ultimately led to Manna's release, during his first term as president.
Yahoo
18-04-2025
- Health
- Yahoo
Humans Could Grow Entirely New Teeth in Just a Few Years, Scientists Say
As helpful as they are to many, fillings and dental implants can be detrimental, and while they have long been the only solutions to decay, it may soon be possible for teeth to regrow themselves. A team of researchers figured out the ideal hydrogel to grow teeth from stem cells in vitro. In the future, entire teeth could be grown in that hydrogel and implanted, or tooth cells could get their start in the hydrogel and continue growing inside the mouth. Sitting in a dentist's waiting room is a dread that can only be numbed by Novocaine. No one wants a drill in their mouth, after all. But what if you never needed a root canal again, and could instead just grow entirely new teeth? Humans don't have the advantage of regenerating teeth like elephants or sharks. Until now, we've only had one chance to grow replacement teeth, and that passed us by at the age when most of us believed in the tooth fairy. After that, it's fillings and crowns all the way down. The problem with fillings is that they don't last forever and can weaken tooth structure, which causes sensitivity and (possibly) further decay. Artificial dental implants may look like teeth, but they can't restore tooth function and can lead to further complications. But there may finally be a solution which may minimize your visits to that ominous chair. While growing teeth in a lab has been attempted before, there was something missing. Now, a team of researchers led by Xuechen Zhang from the Faculty of Dentistry at King's College, London, has finally figured out the ideal environment for teeth to grow on their own in vitro. When teeth grow, the environment they grow in allows stem cells to communicate, sending signals that cause those stem cells differentiate into tooth cells. Previous experiments had not yet come up with an environment close enough to actual gums, which led to signals being sent all at once and disrupting the process. Zhang's team used hydrogels to develop a material, or matrix, close enough to the environment in the body for cells to send signals to each other in the right order and allow tooth organoids to grow. 'The development of tooth organoids involves the self-organization of cells into structures that mimic the cellular composition and functional attributes of the actual teeth,' he said in an study recently published in ACS Macro Letters. 'When these structures are transplanted in vivo, they can then fully develop into mature teeth.' Either pluripotent or tissue-resident stem cells can be used as tooth starters. Pluripotent stem cells can self-renew, and are versatile enough to differentiate into most tissues in the body. Tissue-resident stem cells, on the other hand, are tissue-specific progenitor cells that exist in all tissues and are used either for development or for replacement in case of injury. The cells used by Zhang came from mouse embryos, but he had used human cells in previous experiments, and plans to use them again in future research. Embryonic stem cells from two groups of mice were combined to create cell pellets that were then cultured to grow teeth. Several different hydrogels were tried, and how successfully the teeth grew from these stem cells depended on the properties of the different hydrogels. The developing teeth with the most structure and definition grew in a matrix that had the lowest stiffness and highest swelling, and were the only ones that actually grew into organoids. These fully developed organoids had both an epithelium (outer enamel layer) and mesenchyme (tooth pulp). 'To regenerate teeth through tissue engineering, epithelial and mesenchymal cells must interact within a [matrix] that facilitates these interactions, resulting in tooth organoids that can fully develop into teeth in vivo,' Zhang and his team said in the study. Growing an entire new tooth—or starting the process so that the cells can continue it when implanted—will require biomaterials like this recently developed hydrogel. Human teeth really could someday be grown in a lab, and one day, it may even be possible to inject stem cells into the gums and grow an entire new tooth right in your mouth. If you can avoid getting cavities for at least a few more years, you might never have to hear the sound of that drill again. You Might Also Like The Do's and Don'ts of Using Painter's Tape The Best Portable BBQ Grills for Cooking Anywhere Can a Smart Watch Prolong Your Life?