Latest news with #Olynyk
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India.com
3 days ago
- Health
- India.com
Study Finds Genetic Variant That Doubles Dementia Risk In Men: What You Need To Know
New Delhi: Australian researchers have identified a common genetic variant that doubles the risk of dementia in men. The team from Curtin University said that one in three people carry one copy of the variant, known as H63D, while one in 36 carry two copies. The research, published in the journal Neurology, found that men who carry a double H63D variant are twice as likely to develop dementia in their lifetime compared to women. The study, based on 19,114 healthy older people in Australia and the US, investigated whether people who had variants in the hemochromatosis (HFE) gene, which is critical for regulating iron levels in the body, might be at increased risk of dementia. "Having just one copy of this gene variant does not impact someone's health or increase their risk of dementia. However, having two copies of the variant more than doubled the risk of dementia in men, but not women," said Professor John Olynyk, from the Curtin Medical School. "While the genetic variant itself cannot be changed, the brain pathways which it affects -- leading to the damage that causes dementia -- could potentially be treated if we understood more about it," Olynyk added. Professor Olynyk said further research was needed to investigate why this genetic variant increased the risk of dementia for males but not females. "The HFE gene is routinely tested for in most Western countries, including Australia, when assessing people for hemochromatosis -- a disorder that causes the body to absorb too much iron. Our findings suggest that perhaps this testing could be offered to men more broadly," Olynyk said. While the HFE gene is critical for controlling iron levels in the body, the team found no direct link between iron levels in the blood and increased dementia risk in affected men. "This points to other mechanisms at play, possibly involving the increased risk of brain injury from inflammation and cell damage in the body," Olynyk said. The findings could help improve outcomes for people at risk of developing dementia and pave the way for more personalised approaches to prevention and treatment, especially for men with the double H63D variant.
Hans India
3 days ago
- Health
- Hans India
Study finds common gene variant that doubles dementia risk for men
Australian researchers have identified a common genetic variant that doubles the risk of dementia in men. The team from Curtin University said that one in three people carry one copy of the variant, known as H63D, while one in 36 carry two copies. The research, published in the journal Neurology, found that men who carry a double H63D variant are twice as likely to develop dementia in their lifetime compared to women. The study, based on 19,114 healthy older people in Australia and the US, investigated whether people who had variants in the hemochromatosis (HFE) gene, which is critical for regulating iron levels in the body, might be at increased risk of dementia. "Having just one copy of this gene variant does not impact someone's health or increase their risk of dementia. However, having two copies of the variant more than doubled the risk of dementia in men, but not women," said Professor John Olynyk, from the Curtin Medical School. "While the genetic variant itself cannot be changed, the brain pathways which it affects -- leading to the damage that causes dementia -- could potentially be treated if we understood more about it," Olynyk added. Professor Olynyk said further research was needed to investigate why this genetic variant increased the risk of dementia for males but not females. "The HFE gene is routinely tested for in most Western countries, including Australia, when assessing people for hemochromatosis -- a disorder that causes the body to absorb too much iron. Our findings suggest that perhaps this testing could be offered to men more broadly," Olynyk said. While the HFE gene is critical for controlling iron levels in the body, the team found no direct link between iron levels in the blood and increased dementia risk in affected men. "This points to other mechanisms at play, possibly involving the increased risk of brain injury from inflammation and cell damage in the body," Olynyk said. The findings could help improve outcomes for people at risk of developing dementia and pave the way for more personalised approaches to prevention and treatment, especially for men with the double H63D variant.
Yahoo
25-03-2025
- Sport
- Yahoo
Fantasy Basketball Waiver Wire: Kelly Olynyk remains undervalued
We're entering the home stretch. There are only three more weeks left of the 2024-25 regular season. Plenty of fantasy leagues have wrapped up, while others are entering their championship weeks. Unfortunately, that lines up with plenty of teams pulling the plug on their season. Whether to intentionally improve lottery odds or to allow their stars to rest before the postseason, there are a lot of lineup shenanigans going on every single night across the league. That makes it quite difficult to find a reliable player to add off the waiver wire. Sometimes, players go from playing 20 minutes a night to randomly not being part of the rotation. Did anyone else have to stream Tristan Vukcevic last week and is bitter about him playing four minutes against New York on Saturday? Or was that just me? These players have upside as streaming options (or in some cases are simply low-rostered players), but that sadly doesn't make them safe. PF/C Kelly Olynyk (16% rostered in Yahoo! leagues), New Orleans Pelicans Olynyk has been locked into a starting role since being traded to New Orleans, and he had one of his best games as a Pelican on Monday. He contributed 14 points, 11 rebounds, seven assists and three steals in just 30 minutes. Over the past two weeks he has averaged 11.7 points, 5.3 rebounds, 4.8 assists and 1.2 steals in 26.9 minutes per game. Unfortunately, they only have two more games this week, which means that it may be best to wait to pick Olynyk up until this weekend since they play on Friday and Sunday. SF/PF Aaron Nesmith (28%), Indiana Pacers Nesmith spent a large portion of the season injured, but since returning in January, he has only missed one game. He finished with 17 points, seven rebounds and three triples on Monday while making seven of his nine shot attempts. Nesmith ranks 75th in nine-cat leagues over the past two weeks, per Basketball Monster. PG/SG Anthony Black (4%), Orlando Magic Though he has been inconsistent and disappointing for most of the season, the 2023 lottery pick has displayed some flashes recently. Over Orlando's last four games, he has averaged 13.5 points, 4.5 rebounds, 4.3 assists, one steal and 1.8 triples while shooting 64.5 percent from the floor. As long as Cole Anthony remains out, Black has upside. PG/SG Bub Carrington (10%), Washington Wizards It has been a rough stretch for the rookie, but Carrington had a strong performance on Monday with 15 points, 11 rebounds, six assists and two steals. His role is safe, and Kyshawn George exited early with an ankle injury on Monday, which means more touches for Carrington if George remains sidelined. C Kai Jones (20%), Dallas Mavericks Despite Anthony Davis returning to the lineup, Jones remained the Mavs' starting center. Over their last three games, Jones has averaged 13.7 points, nine rebounds and 1.3 assists while shooting a ridiculous 90 percent from the floor. AD will likely sit out in New York on Tuesday, which means more touches for Jones. SF Justin Edwards (34%), Philadelphia 76ers The undrafted rookie continues to be a bright spot for Philly. He has finished with at least 18 points and three three-pointers in five consecutive games. Edwards has provided top-100 value in nine-cat leagues over the past two weeks and is one of the only reliable options on the team as of now. C DeAndre Jordan (4%), Denver Nuggets Jordan has started the last two games for Denver and averaged 10.5 points, 16 rebounds, 5.5 assists and one steal. If Nikola Jokic remains out against the Bucks on Wednesday, and Jordan continues to start, he's worth taking a chance on.
NBC Sports
25-03-2025
- Sport
- NBC Sports
Fantasy Basketball Waiver Wire: Kelly Olynyk remains undervalued
We're entering the home stretch. There are only three more weeks left of the 2024-25 regular season. Plenty of fantasy leagues have wrapped up, while others are entering their championship weeks. Unfortunately, that lines up with plenty of teams pulling the plug on their season. Whether to intentionally improve lottery odds or to allow their stars to rest before the postseason, there are a lot of lineup shenanigans going on every single night across the league. That makes it quite difficult to find a reliable player to add off the waiver wire. Sometimes, players go from playing 20 minutes a night to randomly not being part of the rotation. Did anyone else have to stream Tristan Vukcevic last week and is bitter about him playing four minutes against New York on Saturday? Or was that just me? These players have upside as streaming options (or in some cases are simply low-rostered players), but that sadly doesn't make them safe. PF/C Kelly Olynyk (16% rostered in Yahoo! leagues), New Orleans Pelicans Olynyk has been locked into a starting role since being traded to New Orleans, and he had one of his best games as a Pelican on Monday. He contributed 14 points, 11 rebounds, seven assists and three steals in just 30 minutes. Over the past two weeks he has averaged 11.7 points, 5.3 rebounds, 4.8 assists and 1.2 steals in 26.9 minutes per game. Unfortunately, they only have two more games this week, which means that it may be best to wait to pick Olynyk up until this weekend since they play on Friday and Sunday. SF/PF Aaron Nesmith (28%), Indiana Pacers Nesmith spent a large portion of the season injured, but since returning in January, he has only missed one game. He finished with 17 points, seven rebounds and three triples on Monday while making seven of his nine shot attempts. Nesmith ranks 75th in nine-cat leagues over the past two weeks, per Basketball Monster. PG/SG Anthony Black (4%), Orlando Magic Though he has been inconsistent and disappointing for most of the season, the 2023 lottery pick has displayed some flashes recently. Over Orlando's last four games, he has averaged 13.5 points, 4.5 rebounds, 4.3 assists, one steal and 1.8 triples while shooting 64.5 percent from the floor. As long as Cole Anthony remains out, Black has upside. PG/SG Bub Carrington (10%), Washington Wizards It has been a rough stretch for the rookie, but Carrington had a strong performance on Monday with 15 points, 11 rebounds, six assists and two steals. His role is safe, and Kyshawn George exited early with an ankle injury on Monday, which means more touches for Carrington if George remains sidelined. C Kai Jones (20%), Dallas Mavericks Despite Anthony Davis returning to the lineup, Jones remained the Mavs' starting center. Over their last three games, Jones has averaged 13.7 points, nine rebounds and 1.3 assists while shooting a ridiculous 90 percent from the floor. AD will likely sit out in New York on Tuesday, which means more touches for Jones. SF Justin Edwards (34%), Philadelphia 76ers The undrafted rookie continues to be a bright spot for Philly. He has finished with at least 18 points and three three-pointers in five consecutive games. Edwards has provided top-100 value in nine-cat leagues over the past two weeks and is one of the only reliable options on the team as of now. C DeAndre Jordan (4%), Denver Nuggets Jordan has started the last two games for Denver and averaged 10.5 points, 16 rebounds, 5.5 assists and one steal. If Nikola Jokic remains out against the Bucks on Wednesday, and Jordan continues to start, he's worth taking a chance on.
Yahoo
07-02-2025
- Sport
- Yahoo
Ingram the centrepiece of three trades, Toronto Raptors surprisingly busy at deadline
TORONTO — Brandon Ingram was the centrepiece of three deals the surprisingly busy Toronto Raptors made in the 24 hours before Thursday's NBA's trade deadline. Toronto acquired Ingram from the New Orleans Pelicans for Bruce Brown, Kelly Olynyk of Kamloops, B.C., a 2026 first-round pick and a 2031 second-round pick. "We see Brandon as an integral part of this team's future – he's an elite scorer, he has a really diverse offensive skill set, and adding him to the young core we have is huge as we continue our quest to win in Toronto," said Raptors vice-chairman and president Masai Ujiri in a statement. "At the same time, we welcome Brandon, we need to really thank Bruce and Kelly. "They have been professionals and leaders and they've been great teammates and examples for all of us. We wish them all the best moving forward.' At 27 years old, Ingram is younger than the 28-year-old Brown and 33-year-old Olynyk. The Raptors young core includes Scottie Barnes, Immanuel Quickley and RJ Barrett of Mississauga, Ont. Ingram is in the final year of a five-year, US$158 million contract that is eligible for an extension. The first-round pick was the Indiana Pacers' top-four protected selection in the 2026 draft. The Raptors also traded Davion Mitchell to the Miami Heat for veteran forward PJ Tucker, a 2026 second-round pick, and cash. Toronto also got centre James Wiseman and cash from Indiana for draft considerations. Wiseman was then waived. A six-foot-eight small forward, Ingram is averaging 22.2 points, 5.6 rebounds and 5.2 assists this season but hasn't played since Dec. 7 with a sprained left ankle. A team official said Ingram will be evaluated by Raptors medical staff on the road as Toronto has stops in Oklahoma City on Friday and Houston on Sunday. Toronto acquired Brown on Jan. 17, 2024, as part of a blockbuster deal with the Pacers for all-star Pascal Siakam. He's averaged 8.4 points, 3.8 rebounds and 1.6 assists this season after missing time following off-season arthroscopic knee surgery. Olynyk grew up in Toronto before moving to Kamloops as a teenager. He was traded to his boyhood team by the Utah Jazz on Feb. 8, 2024, ahead of last season's trade deadline. He signed a two-year extension with the Raptors on March 4 worth a reported $26.25 million. Olynyk also started the 2024-25 campaign injured with back issues, but has averaged seven points, 3.6 rebounds and 2.3 assists so far this season. The Raptors acquired Mitchell in an off-season trade with Sacramento. He's averaging 6.3 points, 1.9 rebounds and 4.6 assists in 44 games this season. The second-round draft pick Toronto sent to Miami is from the Los Angeles Lakers. The 39-year-old Tucker, who had two previous stints with the Raptors, is averaging 1.7 points and 2.7 rebounds in 31 games this season. Wiseman had six points and a rebound for the Pacers. He tore his Achilles tendon after shooting a three-pointer in his first game of the season. Toronto (16-36) currently has a 42.1 per cent chance of getting a top four pick in the NBA draft lottery and a 10.5 per cent chance of selecting first overall this summer Duke Blue Devils guard Cooper Flagg is the consensus top pick in the 2025 draft. This report by The Canadian Press was first published Feb. 6, 2025. John Chidley-Hill, The Canadian Press
