Latest news with #Orient
Yahoo
3 days ago
- Health
- Yahoo
‘Stealthy' Endocrine Effects of the COVID Vaccine Discussed in the Journal of American Physicians and Surgeons
TUCSON, Ariz., June 02, 2025 (GLOBE NEWSWIRE) -- Endocrine effects that may result from vaccination are deceptively subtle at their onset. Hence, robust and sensitive pharmacovigilance is needed to discover them, writes Jane Orient, M.D., in the summer issue of the Journal of American Physicians and Surgeons. As of Mar 20, 2023, more than 13 billion COVID-19 vaccine doses had been administered worldwide. Vaccine proponents argue that with such huge numbers of vaccinations, a clear signal for endocrinological complications should be detected by current vaccine surveillance. This has not occurred, but not necessarily due to the absence of adverse endocrine events, Dr. Orient writes. There are two approaches to surveillance, she explains: the adverse events of special interest (AESI) method and organ systems-based surveys. The AESI approach focuses on a few events selected based upon their severity, biological plausibility, and previous association with vaccines. Organ systems-based surveys examine systematically any potential side effects that could affect vital organs. The article summarizes the major vaccine safety monitoring systems, including: the U.S Vaccine Adverse Event Reporting System (VAERS), the EU's EudraVigilance System, the Vaccine Safety Datalink (VSD), V-safe, and the Biologics Effectiveness and Safety System (BEST). These systems rely on the AESI approach due to its low cost and simplicity. However, this method is neither sufficiently robust nor sensitive to detect subtle signs of initial endocrine side effects, Dr. Orient writes. 'In fact, one can argue that overreliance on this method can guarantee that virtually none of the endocrine complications of COVID-19 vaccine will be detected.' Induction of autoimmunity is a well-recognized mechanism for vaccine adverse effects. The cause of many endocrine conditions, including diabetes mellitus and thyroid, adrenal, and pituitary diseases, involves autoimmune mechanisms as well. Unsurprisingly, there are published case series and reviews demonstrating association between vaccinations and endocrine disorders, Dr. Orient states. Those phenomena are overlooked by the AESI approach because it lacks needed sensitivity. 'A potential disaster of yet undetected endocrine side effects of the vaccine is likely unfolding surreptitiously,' she concludes, and 'clinicians need to have a high index of suspicion for this problem in their patients.' The Journal of American Physicians and Surgeons is published by the Association of American Physicians and Surgeons (AAPS), a national organization representing physicians in all specialties since 1943. Contact: Jane M. Orient, M.D., (520) 323-3110, janeorientmd@
Mint
6 days ago
- General
- Mint
Remote fans with lights that add style and comfort to modern homes: Top 7 picks with the latest features and designs
If you love a cool breeze and mood lighting, the best ceiling fan with light in India is exactly what your room needs. It's not just a fan with lighting, it's a statement piece. Think silent performance, remote control, energy-efficient LEDs, and sleek designs that add flair to your ceiling. These remote fans with lights are perfect for living rooms, bedrooms, or even home offices. Product Rating Price value for money LONGWAY Luminair 1200 mm BLDC Ceiling Fan with Remote Control & LED Light | BEE 5 Star Rated | Ultra High Speed 3 Blade Anti-Dust Decorative | 5 Years Warranty (Smoked Brown, Pack of 1) View Details Orient Electric Uniquely Designed I Tome Pro 1200 mm BLDC Ceiling Fan with Remote | LED Indicator Lights, 5 Star Rated Energy Efficient Fan | High Air Delivery, 3 Years Warranty by Orient - Topaz Gold View Details DIGISMART Autumn Mark 1 1200mm Ceiling Fan, 3 Wider Blade, Energy Efficent BLDC 28 Watt Motor Fan, 5 Step Dim LED Light, Full Remote Control, Reversible Mode and Timer, 5 Years Warranty - Smoke Brown View Details Crompton Energion Roverr Underlight 1200mm BLDC Ceiling Fan | Light Dimming Feature | Remote Control | 5 Years Warranty (Pristine White), Pack of 1 View Details premium pick KUHL Platin D8 1500 mm Stylish 65% Power Saving BLDC Ceiling Fan With Remote | Down Light | 38W | 5 Star | Low Noise | Iot -Operate Via Mobile & Alexa | Reverse Mode | Free Installation | Teak View Details View More You can control the speed, switch the light on or off, and even use timers, all without getting up. It's all about comfort and convenience packed into one stylish fixture. Plus, you get to save space and electricity while staying cool and well-lit. Curious to find out which ones are truly worth spinning for? Let's dive into the most loved and most stylish ceiling fans with lights in the Indian market today. The Atomberg Renesa Enzel 1200mm ceiling fan is a stylish and energy-efficient solution for modern homes. Fitted with a BLDC motor, this BEE 5-star rated fan consumes only 35W, significantly reducing electricity bills. Its high air delivery of 225 CMM ensures excellent cooling across the room. The sleek design, glossy white finish, and LED speed indicator add elegance to any interior. With smart features like remote control, timer, and sleep mode, it offers both comfort and convenience. Suitable for false ceilings, it's engineered for versatility and quiet operation under 57 dB. Dimensions 58.5D x 22W x 22.5H cm Saves up to 65% on energy Sleek and modern design Slightly expensive compared to non-BLDC fans What are buyers saying on Amazon? Buyers appreciate its stylish look, energy efficiency, and ease of remote operation, with special mention of the quiet performance. Choose this fan for energy savings, elegant design, silent performance, and smart remote features with LED indicators. LONGWAY Luminair ceiling fan with led light and remote brings style and performance together with its smoked brown ceiling fan. Featuring an ultra-energy-efficient 28W BLDC motor, this BEE 5-star rated fan ensures robust airflow of 230 CMM while significantly cutting down on electricity costs. The stylish metallic matt finish elevates the ambience of any room. It handles voltage fluctuations with ease and runs efficiently on inverters. The fan comes with a smart IR remote to toggle between 6 speed levels, timer, and boost modes for an elevated user experience. Dimensions 56D x 27.5W x 26H cm Mounting Type Ceiling Mount Very good airflow at 230 CMM Runs well during voltage fluctuations Remote design could be more ergonomic What are buyers saying on Amazon? Buyers love the airflow, design, and value-for-money proposition, especially highlighting its energy savings and smooth inverter operation. Opt for this fan if you want high-speed airflow, long inverter run-time, and a designer matte finish. Orient Electric's I Tome Pro is amongst the best ceiling fan with light in India. It combines elegance with advanced BLDC motor technology to offer efficient cooling with minimal energy consumption. Using just 26W at maximum speed, it helps you cut your power bills by up to 65%. The remote-controlled fan provides convenience at your fingertips with speed adjustments, timer, and boost functions. The LED speed indicator lights are gentle yet functional, making it ideal for nighttime use. With its 1200 mm sweep and 220 CMM air delivery, it offers powerful cooling even during low voltage scenarios. Lower power consumption Gentle LED speed indicators Fewer speed levels compared to other models What are buyers saying on Amazon? Buyers mention its sleek look, effective remote functions, and super low power usage as the highlights of this fan. Pick this fan for unmatched energy efficiency, elegant aesthetics, and inverter-friendly usage during power cuts. DIGISMART Autumn Mark 1 is a feature-rich BLDC ceiling fan ideal for modern homes. This fan with lighting comes with 28W motor that ensures power savings without compromising on speed—it delivers 380 RPM and comes with wider blades for efficient air circulation. The aerodynamic blades and high-flow technology make it effective in larger spaces. With a universal IR remote offering 6 speeds, timer, sleep, and boost modes, it is incredibly user-friendly. The 5-step dim LED light adds utility and charm, while the reversible mode enhances comfort across seasons. High RPM for strong air delivery Reversible mode for seasonal use Slightly heavier fan body What are buyers saying on Amazon? Buyers praise the strong airflow, dimmable LED, and easy-to-use remote. Many highlight the fan's value for features offered. Go for this if you want strong airflow, LED dim lighting, seasonal reverse mode, and long inverter performance. The Crompton Energion Roverr Underlight is a premium ceiling fan designed to enhance both cooling and ambience in your living spaces. Sporting a sleek Pristine White finish, this fan features energy-efficient ActivBLDC technology, which consumes only 37 watts while delivering strong air circulation. Its integrated LED underlight with three dimming levels adds a modern and elegant touch, making it ideal for bedrooms, dining areas, and living rooms. With a five-year warranty and a point-anywhere remote for speed, dimming, and timer functions, this fan is built for convenience, energy savings, and style. Mounting Type Downrod Mount LED underlight with dimming feature adds elegance Point-anywhere remote control for convenience What are buyers saying on Amazon? Buyers love the energy-saving performance, silent operation, and stylish look, especially the ease of remote-controlled lighting. Choose this for its stylish design, underlight functionality, and superior energy efficiency with a reliable 5-year warranty. The KUHL Platin D8 is not just a ceiling fan; it's a smart, stylish, and energy-efficient appliance built for modern homes. With an extra-large 1500 mm sweep and 8 aerodynamic blades, it delivers superior air performance while maintaining ultra-low noise. The IoT-enabled features let you control the fan via mobile apps or voice assistants like Alexa, making it an intelligent addition to any room. It includes a down light with adjustable colours and a point-anywhere remote. Designed for comfort, convenience, and energy savings, the fan consumes just 38W at full speed. Blades 8 aerodynamic blades Mounting Type Ceiling Mount IoT-enabled with mobile and Alexa control Reverse mode for winter air circulation Requires internet setup for full smart features What are buyers saying on Amazon? Buyers appreciate its smart connectivity, elegant design, quiet performance, and the versatility of its lighting and control features. Opt for this if you want a smart, voice-controlled ceiling fan with elegant looks and ultra-efficient power savings. The DIGISMART Autumn Mark 1 is a sleek and affordable BLDC ceiling fan equipped with powerful performance features. Designed with a high-speed 380 RPM motor, this fan ensures strong airflow while consuming only 28 watts of energy. Its stylish smoke brown design blends well with modern home décor, and the full-feature remote allows control over six-speed settings, boost mode, reverse function, LED dimming, and a timer. Ideal for a variety of indoor spaces, it promises long life, quiet operation, and up to 65% energy savings. It's an all-in-one fan that's efficient, stylish, and user-friendly. Excellent airflow with high RPM 6-speed remote with timer and sleep mode IR remote requires direct line-of-sight What are buyers saying on Amazon? Buyers find it a value-for-money option with great airflow, modern design, and silent operation, especially impressed by the LED lighting. Pick this for high-speed airflow, reversible mode, and excellent energy savings in a stylish and budget-friendly design. Yes, remote-controlled fans offer convenience, energy efficiency, and smart features like a timer, reverse mode, and light dimming. They're especially useful in bedrooms and living areas where you want control without moving. Most also use BLDC motors, which consume less power than traditional induction fans. BLDC (Brushless Direct Current) motors are more efficient, quieter, and longer-lasting than traditional motors. They consume up to 65% less electricity and are ideal for running on inverters during power cuts. Fans with these motors also support advanced features like 6-speed control, sleep mode, and voice operation. Reverse mode allows the fan blades to rotate in the opposite direction. This is especially useful in winters to push warm air down from the ceiling. It helps maintain consistent room temperature and improves energy efficiency in both summer and winter. Motor Type: Opt for BLDC motors for better efficiency and lower power consumption. Light Control: Choose fans with dimmable LED light settings for custom ambience. Remote Features: Ensure the remote offers multiple speed settings, timer, and light control. Noise Level: Look for quiet operation if the fan is for bedrooms or workspaces. Smart Integration: Prefer IoT-enabled fans for mobile app and voice control support. Air Delivery (CMM): Higher CMM means better airflow; look for fans with 230+ CMM. Warranty & Support: Go for fans with at least a 3- to 5-year warranty and good service network. Design & Finish: Choose a style and colour that blends well with your room decor. Inverter Compatibility: Ensure it runs efficiently during power outages. Best remote fans with lights Material Number of speed Special Feature atomberg Renesa Enzel 1200mm BLDC Ceiling Fan with Remote Control Aluminium 6 Low noise, LED Speed Indicator LONGWAY Luminair 1200 mm BLDC Ceiling Fan with Remote Control 100% CNC Binding, Metal, Copper 6 Timer, Safety Certified, Inverter Compatible Orient Electric Uniquely Designed I Tome Pro 1200 mm BLDC Ceiling Fan Aluminium 5 5-star rated BLDC ceiling fan consumes 65% less energy DIGISMART Autumn Mark 1 1200mm Ceiling Fan Copper 6 Double Ball Bearing, Metal Finish Looks Crompton Energion Roverr Underlight 1200mm BLDC Ceiling Fan Plastic, Aluminium 3 ActivBLDC Technology KUHL Platin D8 1500 mm Stylish BLDC Ceiling Fan Plastic 3 Low Noise, Iot -Operate Via Mobile & Alexa DIGISMART Autumn Mark 1 1200mm Ceiling Fan Copper 6 380 RPM High Speed BLDC Motor Disclaimer: Mint has an affiliate marketing partnership, which means we may get some commission on purchases you make through the retailer sites links provided. These partnerships do not influence our editorial content, which is free from any bias or marketing pitch. We strive to provide accurate and unbiased information to help you make informed decisions. We recommend verifying details with the retailer before making a purchase.
Yahoo
29-05-2025
- Business
- Yahoo
BigBear.ai vs. Palantir: Which AI Defense Stock Is the Smarter Buy?
In the rapidly evolving landscape of artificial intelligence (AI) and defense technology, two companies have emerged as notable players - Holdings Inc. BBAI and Palantir Technologies Inc. PLTR. Both firms specialize in providing AI-driven analytics and solutions to the government and defense sectors, leveraging cutting-edge technologies to enhance decision-making and operational focuses on delivering predictive analytics and autonomous systems, catering to various defense and intelligence agencies. Palantir, on the other hand, offers comprehensive data integration and analysis platforms, serving a broad spectrum of government and commercial clients. The commonality between these companies lies in their commitment to harnessing AI for national security and defense the increasing emphasis on AI in defense strategies and the substantial government investments in this domain, comparing and Palantir becomes particularly relevant for investors seeking exposure to this dive deep and closely compare the fundamentals of the two stocks to determine which one is a better investment now. is a smaller pure-play in the defense/intelligence AI arena. The company has carved out a niche providing 'decision intelligence' solutions to U.S. government and military clients. It has scored several key government contracts that showcase its capabilities – for example, a 3.5-year, $13.2 million sole-source award to enhance the Pentagon's ORION analytics platform for force management. suite of AI tools (with modules like Observe, Orient, and Dominate) ingests data, identifies patterns, and predicts outcomes at the network edge. These technologies are used in simulations and planning for complex military scenarios, though on a far smaller scale than Palantir's deployments. The recent appointment of a new CEO – former DHS acting secretary Kevin McAleenan – in January 2025 stirred optimism that Washington connections could translate into new contract wins. This niche focus led to significant contract wins and a swelling backlog of orders. At the end of first-quarter 2025, BigBear's contract backlog stood at $385 million, leaping 30% from a year ago, indicating a solid pipeline of future revenue from government the company significantly improved its balance sheet, ending the quarter with $108 million in cash, more than double its cash balance at the end of 2024. The reduction of debt from $200 million to $142 million—primarily through equity conversions—has provided greater financial flexibility and reduced interest burden, enabling BigBear to better weather macro uncertainty and continue funding strategic growth initiatives. A key challenge in first-quarter 2025 stemmed from delays in federal procurement processes. These delays created temporary variability in revenue recognition and underutilization of available resources, pushing up SG&A costs. Management highlighted that while such delays are typical in government contracting, they had a meaningful short-term impact on the company's bottom line, contributing to a wider adjusted EBITDA loss. Additionally, while revenue rose modestly, the company's financials were impacted by higher non-cash expenses, including increased stock-based compensation and derivative fair value adjustments. Palantir Technologies is a far larger and more established player at the intersection of AI and defense. The company built its reputation with Gotham, a platform for U.S. intelligence and defense agencies that integrates vast data sets to enable real-time decision-making. Alongside Gotham, Palantir's commercial-oriented Foundry platform and its new Artificial Intelligence Platform form a comprehensive suite that bridges government and enterprise AI needs. This end-to-end AI strategy, from data integration and preparation to advanced analytics, gives Palantir a formidable competitive continually aligns its technology with defense priorities; for example, it's working on the Pentagon's high-profile Open DAGIR initiative to modernize mission planning with AI, showcasing its ability to upgrade military operations with cutting-edge data solutions. This month, Palantir announced an extension of its Army Project Maven work that brought the total value of that program to over $1 billion, marking Palantir's first billion-dollar contract. This underscores the company's revenue visibility in defense AI at scale, far beyond what a smaller firm like BigBear can achieve. Furthermore, Palantir is expected to be a key beneficiary of the Trump administration's "Golden Dome" missile defense initiative, highlighting its integral role in national defense has also been rapidly expanding its commercial footprint, applying its AI prowess to industries like healthcare, finance, manufacturing, and logistics. Importantly, Palantir is now a profitable and fast-growing business. In the first quarter of 2025, Palantir's revenue surged 39% year over year to $884 million, handily beating expectations. U.S. revenue alone jumped 55%, reflecting strong uptake of its AI solutions domestically. The company has posted multiple quarters of GAAP profitability, with adjusted earnings of 13 cents per share (up from 8 cents a year prior). Off the back of robust demand, Palantir raised its full-year 2025 outlook – now guiding for $3.89–3.90 billion in revenue (about up 36% year over year), well above its initial forecasts. In other words, Palantir's fundamental trajectory is decidedly upward, fueled by booming AI adoption across both its defense and commercial segments. The company's financial position is also a source of strength – Palantir sits on $5.4 billion in cash (as of March 31) and carries no debt, giving it ample flexibility to invest in R&D or acquisitions to maintain its faces challenges, including sustaining its growth rate as a larger company and managing its heavy reliance on government contracts, which exposes it to political and budgetary risks. Despite its innovative offerings, stock's performance has been underwhelming in 2025, with a year-to-date (YTD) decline of 7% and below the Zacks Computer and Technology sector's 1.3% decline. However, the stock has shown signs of recovery, gaining about 21.4% over the past 2025, Palantir's stock has experienced significant growth, with a YTD increase of 63.6% and a modest gain of 4.4% over the past month. Image Source: Zacks Investment Research BBAI is trading at a 6.87X forward 12-month price-to-sales (P/S) ratio, higher than its three-year median of 1.9X and higher than the Zacks Computer and Technology sector's 6.25X. It may need clear signs of improving execution or a shift in federal spending trends to regain bullish valuation has become very stretched after the massive run. Palantir trades at about 66.85X, far above BBAI and the sector. Image Source: Zacks Investment Research Over the past 30 days, the Zacks Consensus Estimate for PLTR has increased, while for BBAI stock, the loss per share has widened for 2025, as you can see below. The estimated figure indicates 43.9% growth for PLTR. On the other hand, the estimated figure for BBAI indicates a narrower loss from $1.10 per share a year ago. For BBAI Stock Image Source: Zacks Investment Research For PLTR Stock Image Source: Zacks Investment Research While offers a compelling niche in defense-focused AI, its smaller scale, inconsistent financials, and exposure to procurement delays make its growth path less predictable. The company's Zacks Rank #4 (Sell) hints at near-term pessimism. In contrast, Palantir's superior fundamentals, diversified revenue base, and execution strength position it as the more robust investment. After weighing the fundamentals, Palantir — a Zacks Rank #3 (Hold) company — appears to hold the better upside potential right now, albeit with some valuation-induced caution. All things considered, investors looking for exposure to the AI-defense theme would be better served by Palantir's proven growth and resilience at this point, as it currently offers a more compelling risk-reward profile than its smaller rival. You can see the complete list of today's Zacks #1 Rank (Strong Buy) stocks here. Want the latest recommendations from Zacks Investment Research? Today, you can download 7 Best Stocks for the Next 30 Days. Click to get this free report Palantir Technologies Inc. (PLTR) : Free Stock Analysis Report Holdings, Inc. (BBAI) : Free Stock Analysis Report This article originally published on Zacks Investment Research ( Zacks Investment Research Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
South Wales Guardian
26-05-2025
- Sport
- South Wales Guardian
Charlton promoted to Championship after beating Leyton Orient in play-off final
No-nonsense defending from both sides led to a scrappy opening period with goal opportunities at a premium. It took 31 minutes for the game to spark into life but the wait was worth it with a sublimely executed free-kick by Gillesphey breaking the deadlock. Tyreece Campbell, always a threat, was fouled outside the penalty box and Gillesphey curled his set-piece delivery from 20 yards past the wall and wide of Orient keeper Josh Keeley who got his fingers to the ball but could not prevent it from nestling into the net. Charlton enjoyed the better of the possession in the first half whilst nervy Orient struggled to impose themselves on the game and the Addicks looked more comfortable on the ball. THE. ADDICKS. ARE. BACK. 😎#cafc — Charlton Athletic FC (@CAFCofficial) May 25, 2025 Campbell and skipper Greg Docherty exchanged passes in a potentially threatening move but Campbell's weak cross was comfortably collected by Keeley while Orient provided little concerns for Addicks shot-stopper Will Mannion. The teams came into the match in a rich vein of form, each having only tasted defeat once in each of their last 10 matches. The Addicks completed the scheduled league season in fourth spot, seven points ahead of the O's whose run of six successive victories at the death earned them the final play-off position. Orient raised their tempo in the second half, taking the game to their opponents from the restart. Jack Currie sent in a powerful drive that was deflected for a corner and then League One's leading scorer Charlie Kelman saw his goal-bound drive deflected onto the crossbar. 🏆 @CAFCofficial #SteppedUp! 📈🔴#EFLPlayOffs | #StepUp — Sky Bet League One (@SkyBetLeagueOne) May 25, 2025 Then Jamie Donley was brought down on the edge of the penalty area but his resultant free-kick was blocked by the resolute Charlton defence. Keeley kept Orient in the game when he dealt with an effort from Conor Coventry before he tipped a well-struck effort from substitute Chuks Aneke over the bar but Orient kept pushing forward in search of the equaliser. However, a combination of a lack of quality to their final touch and pass and the well-drilled determined unwavering steely defending of their opponents for whom Lloyd Jones was outstanding proved too much to overcome. The return to the second tier of English football was a triumph for Charlton boss Nathan Jones. He had led Luton to promotion and can now add Charlton to his list of successes having taken over as boss of the club in February 2024.
Rhyl Journal
25-05-2025
- Sport
- Rhyl Journal
Charlton promoted to Championship after beating Leyton Orient in play-off final
No-nonsense defending from both sides led to a scrappy opening period with goal opportunities at a premium. It took 31 minutes for the game to spark into life but the wait was worth it with a sublimely executed free-kick by Gillesphey breaking the deadlock. Tyreece Campbell, always a threat, was fouled outside the penalty box and Gillesphey curled his set-piece delivery from 20 yards past the wall and wide of Orient keeper Josh Keeley who got his fingers to the ball but could not prevent it from nestling into the net. Charlton enjoyed the better of the possession in the first half whilst nervy Orient struggled to impose themselves on the game and the Addicks looked more comfortable on the ball. THE. ADDICKS. ARE. BACK. 😎#cafc — Charlton Athletic FC (@CAFCofficial) May 25, 2025 Campbell and skipper Greg Docherty exchanged passes in a potentially threatening move but Campbell's weak cross was comfortably collected by Keeley while Orient provided little concerns for Addicks shot-stopper Will Mannion. The teams came into the match in a rich vein of form, each having only tasted defeat once in each of their last 10 matches. The Addicks completed the scheduled league season in fourth spot, seven points ahead of the O's whose run of six successive victories at the death earned them the final play-off position. Orient raised their tempo in the second half, taking the game to their opponents from the restart. Jack Currie sent in a powerful drive that was deflected for a corner and then League One's leading scorer Charlie Kelman saw his goal-bound drive deflected onto the crossbar. 🏆 @CAFCofficial #SteppedUp! 📈🔴#EFLPlayOffs | #StepUp — Sky Bet League One (@SkyBetLeagueOne) May 25, 2025 Then Jamie Donley was brought down on the edge of the penalty area but his resultant free-kick was blocked by the resolute Charlton defence. Keeley kept Orient in the game when he dealt with an effort from Conor Coventry before he tipped a well-struck effort from substitute Chuks Aneke over the bar but Orient kept pushing forward in search of the equaliser. However, a combination of a lack of quality to their final touch and pass and the well-drilled determined unwavering steely defending of their opponents for whom Lloyd Jones was outstanding proved too much to overcome. The return to the second tier of English football was a triumph for Charlton boss Nathan Jones. He had led Luton to promotion and can now add Charlton to his list of successes having taken over as boss of the club in February 2024.
