Latest news with #Parkins
Scientific American
3 days ago
- Health
- Scientific American
Ozzy Osbourne's Death Puts Spotlight on Rare Form of Parkinson's
On July 22, Ozzy Osbourne, lead singer of Black Sabbath, died at age 76. The 'Prince of Darkness' had been outspoken about keeping up with stage performances and touring while undergoing care for a rare form of Parkinson's disease called Parkin —named after the gene PRKN which is linked to the disease. He played his last live performance with his bandmates in Birmingham, England on July 5. 'It's been terribly challenging for us all,' Osbourne said in a 2020 Good Morning America interview when he publicly announced his diagnosis. 'There's so many different types of Parkinson's,' Osbourne's wife, Sharon, said during the interview. 'It's not a death sentence by any stretch of the imagination, but it does affect certain nerves in your body.' On supporting science journalism If you're enjoying this article, consider supporting our award-winning journalism by subscribing. By purchasing a subscription you are helping to ensure the future of impactful stories about the discoveries and ideas shaping our world today. Osbourne's cause of death was not disclosed. The late heavy metal musician had often openly shared his intense lifestyle and experience with drug use, which may have worsened the progression of his form of Parkinson's, according to the New York Times. What Do We Know About Parkin? Parkinson's disease is a neurodegenerative condition in which nerve cells, largely in the basal ganglia of the brain, deteriorate or die. According to the National Institutes of Aging, the illness typically progresses with age (most people develop the disease after age 60) and is known for causing tremors, stiff muscles, balance issues, slowed movement and other mobility problems. People may also experience difficulty swallowing, chewing and speaking as well as mental health issues, including depression and mood changes. Emerging research suggests that acting out dreams might also predict Parkinson's disease. PRKN, which is one of the genes implicated in Parkinson's disease, is involved in maintaining mitochondrial function, which could affect cellular energy—but how that exactly leads to disease is unclear, according to Medline Plus. Parkinson's disease is linked to more than 200 mutations, some of which may cause issues with protein production, durability and function. In the 2020 Good Morning America interview, the Osbourne family disclosed that he had Parkin 2.[LY1] Osbourne had volunteered to have his genome sequenced in 2010 to see if his DNA could offer more clues about his health and condition. 'He was really curious to know about his Parkinson's-like symptoms, so we looked pretty closely in his genome for that kind of stuff. We found a few hints, but we couldn't tell him why he has symptoms like a tremor. And frankly, his history of drug abuse probably contributed to that, too,' Nathan Pearson, then research director of Cofactor Genomics which sequenced Osbourne's genome, told Scientific American in 2010. Does Parkinson's Disease Cause Death? Data on Parkinson's disease and mortality are inconsistent, with some studies suggesting that those with the condition, particularly an advanced or severe form, have about a 1.5 times higher death rate than the general population, according to the American Parkinson Disease Association. Parkinson's disease in combination with another disease or injury, such as a fall, ulcer or pneumonia, could also increase the likelihood of death. While uncurable, Parkinson's is considered a livable disease. Drugs that act on certain brain neurotransmitters, including dopamine —a hormone involved in movement—can help alleviate symptoms. Research on deep-brain stimulation, which was approved by the U.S. Food and Drug Administration for Parkinson's tremor in 1997, has shown the technology to be a highly effective treatment.
Fox Sports
02-05-2025
- Sport
- Fox Sports
Danny Parkins' 2026 NFL mock draft: Why Arch Manning might not be a No. 1 lock
The 2025 NFL Draft has come and gone. Now, fans are learning about their favorite team's drafted players and hoping they can be the missing pieces for a playoff or title run in the years ahead. As some are wondering how this year's class will impact the upcoming season, though, Danny Parkins of FS1's "Breakfast Ball" is imagining what the top of the 2026 NFL Draft will look like. In his first mock draft for next year, Parkins projected the 10 worst teams in the league and what their biggest needs will be entering draft weekend. "I really, really miss the NFL, so I figured no time like the present," Parkins said. "Let's fast-forward to the 2026 NFL Draft. This is a fun exercise because you're trying to figure out the players in college who are going to be in the top 10 and the teams that are going to be bad enough to be drafting in the top 10." Let's take a look at how Parkins envisions the top 10 shaking out in the 2026 NFL Draft, with odds via DraftKings Sportsbook. Odds to be No. 1 pick: +225 Parkins' thoughts: "My guess is everyone in the world is going to mock Arch Manning to the Saints because his grandfather is Archie Manning. It's the first family of football — the Mannings, New Orleans. Everyone in the world is going to do that. But, I've got to say, it's not going to be as easy of a decision as people think. Garrett Nussmeier, the quarterback out of LSU … is a gunslinger, he's got a huge arm. The Saints just hired Kellen Moore as their head coach. Garrett Nussmeier's father (Doug) is the offensive coordinator of the Saints. So, if Nussmeier has as good of a season as I expect him to have with all the talented players around him at LSU, do they take Archie Manning's grandson when Archie Manning is a Saints legend, or do they take their offensive coordinator's son who played right down the road in Baton Rouge? I think the Saints go with Arch Manning." Odds to be No. 1 pick: +500 Parkins' thoughts: "Sorry to Shedeur Sanders and Dillon Gabriel. I don't think you guys are the answer for the Browns [at quarterback] of the future. I think Nussmeier has a big year and goes to the Browns." Odds to be No. 1 pick: +7500 Parkins' thoughts: "Clemson's defense is going to be the best in the country this year. The Jets take the big boy in the middle of the defensive line, Peter Woods. He had nine tackles for loss last year. [Defensive tackle] is the biggest need for the Jets, outside of quarterback. But with quarterbacks going 1-2 — and I don't fully believe in Drew Allar out of Penn State, I still need to see more out of that one to believe it — the next biggest need is on the D-line. So, they go with a blue-chip player who's a massive, mammoth of an individual from a great program that's produced monsters on the defensive line in the NFL." Odds to be No. 1 pick: +5000 Parkins' thoughts: "Rueben Bain is an absolute stud. You wanna add at a premium position. The Colts could be looking to add a premium quarterback if they're drafting in the top four. I understand that, but how many quarterbacks are going to be there? The second-most valuable position in the NFL, other than the quarterback, is the guys who stop the quarterback." Odds to be No. 1 pick: +2500 Parkins' thoughts: "The Panthers are probably a little disappointed that Rueben Bain comes off the board. They go right back to the Clemson Tigers defense with T.J. Parker. The Panthers … were the worst pass-rushing team in the NFL. They tried to help Bryce Young [with their first-round pick in this year's draft] and picked Tetairoa McMillan. This is the year, with quarterback off the board, that they do their best to, frankly, fix the biggest hole on their team. I understood why they took McMillan. They need to make the Bryce Young investment work and do everything they could there. They'll be just good enough to not get a top pick. They'll roll it out with Bryce Young for one more year." Odds to be No. 1 pick: +5000 Parkins' thoughts: "How do you help Cam Ward? You draft a mountain of a man, the 6-foot-7, 370-pound Kadyn Proctor. You can either give the guy a pass-catcher or a pass protector. I think in this spot, in this draft, the Titans go to Alabama and take Kadyn Proctor." 7. New York Giants: Francis Mauigoa, OT, Miami (Fla.) Odds to be No. 1 pick: +3500 Parkins' thoughts: "The Giants would be upset that Proctor comes off the board, but they still go with an offensive tackle. Francis Mauigoa is a very talented player and is the second player out of 'The U' drafted in the top seven. The defense for the Giants is in great shape. They have just drafted Jaxson Dart. They're probably not looking quarterback in this spot. Their defense, especially with that front seven, is locked in. So, is it receiver or is it offensive lineman? Right tackle is the biggest need on that offensive line." 8. Miami Dolphins: Harold Perkins Jr., LB, LSU Odds to be No. 1 overall pick: +4000 Parkins' thoughts: "I know Dolphins fans are going to be disappointed if they're picking in the top eight next year, but I don't think you'll be disappointed if Harold Perkins becomes a Dolphin. He might be the best athlete in college football. Yes, he had the big injury. We'll see what level of production he has going forward. But it's their defensive line that's left a lot to be desired. They've made a lot of investments, some of that is due to injury. But you bring in a true blue-chip, Swiss Army knife of a player that can get to the quarterback, that's a focal point for the Dolphins defense moving forward." Parkins' thoughts: "I think the Raiders are better this year, but not great. Pete Carroll's going to want to build that team from the line of scrimmage. He already took Ashton Jeanty, and they're not ready to move on from Geno Smith [in this scenario]. So, they just go best player available with Caleb Banks, the huge defensive tackle out of Florida. You have Christian Wilkins, who you paid a bunch of money to, and Maxx Crosby, who apparently wants to be a Raider for life, and you add a Caleb Banks to create a top-five defensive line in football. You need a great defense in the AFC West." Odds to be No. 1 overall pick: +2500 Parkins' thoughts: "The Cowboys should be better than this, but I don't know about the coach. I don't know about the depth. At some point, they're going to have a 'fall on their face' year. They'd be thrilled if the board fell like this. Caleb Downs — I don't know whether to list him at safety, cornerback or defensive back — but he might be the best player in all of college football. But because if he's going to be more of a safety, maybe the lack of premium value that's placed at that position makes him fall." Want great stories delivered right to your inbox? 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Chicago Tribune
25-02-2025
- Business
- Chicago Tribune
Former WSCR-AM 670 cohost Danny Parkins sells Wilmette home for $925,000
Former WSCR-AM 670 cohost Danny Parkins, who last year moved to New York to join Fox Sports 1, and his wife, Stephanie, on Dec. 20 sold their four-bedroom, 2,972-square-foot house in Wilmette for $925,000. A New Trier High School alumnus and a Glencoe native, Parkins, 38, joined WSCR-AM in 2017 as an afternoon host alongside Matt Spiegel. In August, he was tapped to cohost the FS1 morning sports-talk show, 'Breakfast Ball.' In Wilmette, Parkins and his wife paid $845,000 in 2021 for the house that they just sold. Built in 1960, the house backs up to the Wilmette Golf Club and has five bathrooms, two fireplaces, an open floor plan, hardwood floors and a living room with a fireplace, ornate ceiling detail and a bay window. Other features include a kitchen with an island, a bar and Viking, Sub-Zero and Bosch appliances, as well as a first-floor en-suite bedroom, a second-floor primary bedroom suite with new hardwood floors, volume ceilings and a bathroom with a dual sink vanity and a walk-in shower. Recently added features include second-floor windows and one of the home's two furnaces, which was added last year. 'It was a pretty spectacular floor plan with exceptional upgrades, on a golf course (and) in an amazing school district. It checked a lot of boxes for a lot of clients,' listing agent Holly Connors of @properties Christie's International Real Estate told Elite Street. 'There were a lot of interested parties, largely because of the first-floor en-suite bedroom.' Parkins and his wife first listed the house in September for $1 million, and found a buyer before the month ended. The house had a $17,095 property tax bill in the 2023 tax year. Parkins isn't the only national sports-talk TV and radio figure dealing in real estate on the North Shore. FS1 midday host Colin Cowherd, who now is based in Chicago, and his wife, Ann, paid $4.45 million in December for a five-bedroom, 7,260-square-foot, vintage French Colonial-style mansion on a 1.24-are property. Cowherd also paid $3.25 million in January 2024 for a three-bedroom, 3,200-square-foot condominium unit on the 25th floor of the Park Tower building in Streeterville.
