Latest news with #Perpetual
Business Wire
10-07-2025
- Business
- Business Wire
TandemAI and Perpetual Medicines Announce Strategic Merger to Expand Physics and AI-Based Drug Discovery Capabilities
SHANGHAI & NEW YORK & BOSTON--(BUSINESS WIRE)--TandemAI, a company transforming drug discovery with state-of-the-art AI and physics-based technologies integrated with full wet lab capabilities, and Perpetual Medicines, which is advancing a computational design-synthesis platform for peptide drug discovery today announced the companies have merged. The combined company, to be known as TandemAI, will provide partners with an expanded range of methods and workflows for both small molecule and peptide drug discovery and bring additional leadership with an extensive track record in drug discovery and development. TandemAI will provide partners with an expanded range of methods and workflows for both small molecule and peptide drug discovery and bring additional leadership with an extensive track record in drug discovery and development Share The combined firm will be led by TandemAI co-founder and CEO, Jeff He, MBA. Perpetual Medicines will function as a separate operating entity within TandemAI, and will be headed by Kerry L. Blanchard, MD, PhD, its co-founder, Chairman and Chief Executive Officer; and Ved Srivastava, PhD, Chief Scientific Officer, Financial and other terms were not disclosed. 'This strategic combination is driven by TandemAI's success in commercializing its physics and AI-based platform for small molecule discovery integrated with wet-lab experimentation and the enormous emerging opportunity afforded by the convergence of high biopharma interest in next generation peptide therapeutics and advances in AI and physics-based methods that are transforming the design and optimization of peptides,' said Lanny Sun, co-founder of Perpetual Medicines and co-founder of TandemAI. 'Perpetual has built and validated an outstanding computational/AI platform for peptide drug discovery. The merger positions TandemAI to be a leader in these approaches as well as to explore their application to other modalities.' 'TandemAI was established with a vision to transform drug discovery by enabling broad access to the most advanced AI and physics based computational tools for integrated drug discovery,' said He. 'Executing on that vision, in less than four years we have collaborated on small molecule discovery programs with more than 150 partners, including biotechnology firms, multi-national pharmaceutical companies, and academic institutions in the U.S., Europe and China. More than ten client programs are expected to reach clinical trials within the next 12 months. With Perpetual's integrated computational-synthesis platform and experienced leadership, we have a major opportunity to advance and accelerate peptide drug discovery with partners.' Mr. He noted that the Perpetual leadership team has been instrumental in the discovery and development of multiple peptide drugs in the U.S., including Byetta ® (exantide), Symlin ® (pramlintide) and Bydureon ® (exantide extended release); marketing approval for Byetta, Bydureon, and Trulicity, and licensing for development of mazdutide in China. Dr. Blanchard has played a key role in four marketed products and the clinical development and approval of more than 30 new medicines in China. 'The commercial and clinical successes of GLP-1, IL-23, and PCSK9 drug classes have greatly expanded the global commercial opportunity for peptide-based therapeutics,' said Dr. Blanchard. 'Our AI/computational platform is designed to capitalize on unexplored peptide chemical space to discover new therapeutics with novel attributes. The synergies we expect to realize through the merger with TandemAI, will greatly accelerate these efforts.' He noted that since its founding in 2023, Perpetual has built and validated its AI/computational platform and automated peptide synthesis technology; achieved preclinical, in vivo proof of concept with its lead program to develop orally available cyclic peptides; and entered a strategic peptide discovery collaboration with a major U.S. venture capital firm. About TandemAI TandemAI is transforming drug discovery by integrating generative AI, physics-based modeling (molecular dynamics and quantum mechanics), AI-powered, next generation SaaS platform, TandemViz™ and largescale chemistry and biology labs. This computation first approach covers the entire drug development process, from target prediction to clinical candidate determination, significantly boosting efficiency and success rates for global pharmaceutical organizations. In just three years, TandemAI has established a global R&D network across New York, Boston, Shanghai, and Suzhou, serving over 150 biopharmaceutical companies and accelerating more than 50 innovative drug pipelines. The company has achieved 10x revenue growth, earning accolades like "China Innovative Digital Healthcare TOP100," "Forbes Asia 100 to Watch," and inclusion in the "Nature Index Global AI Drug Discovery Innovation Landscape." TandemViz™, the world's first one-stop AI-enabled drug discovery platform, integrates computational modules, high-performance computing, and data management, enhancing productivity and accessibility. This platform addresses key R&D challenges, driving rapid wet-dry lab integration and gaining widespread industry recognition. For additional information: About Perpetual Medicines Perpetual Medicines is a fully integrated computational peptide therapeutics company that aims to build a next-generation peptide drug discovery engine. The company's platform combines the predictive power of leading-edge computational physics methods and next-generation AI technologies with advanced synthetic chemistry to access vast, unexplored peptide chemical space. The platform is designed to address previously undruggable targets, accelerate discovery and enhance the quality of peptide drug candidates. The company has operations in Shanghai, China and Boston, MA. Learn more at:
GMA Network
16-06-2025
- Sport
- GMA Network
EAC upsets Perpetual for third win in a row in Filoil preseason action
Red-hot Emilio Aguinaldo College claimed another scalp after upsetting University of the Perpetual Help System DALTA with a convincing 77-52 win in the 18th Filoil EcoOil Preseason Cup on Monday. The Generals rode on the steady shooting of Brianne Angeles, Joshua Tolentino, and Jon Cudiamat to race to their third straight win and hike their record to 5-1, tying De La Salle-College of Saint Benilde at second spot. Angeles top-scored with 12 points laced with four rebounds and one assist while Tolentino and Cudiamat each chipped in 11 markers as the Generals continued to prove that they're a legit title contender come NCAA Season 101. 'Ever since naman, naniniwala kami na kaya naming maging contender. Ang maganda lang is nagde-deliver na yung mga bata sa sistema namin," EAC head coach Jerson Cabiltes said. EAC, which narrowly missed a Final Four spot last Season 100 due to a 9-9 record, was off to a hot start against the struggling Perpetual with Tolentino and other key vets in Kyle Ochavo and Nicole Quinal leading their first quarter barrage, 24-11. It was all EAC since then with Jethro Bacud even sending them to a 26-point cushion after his layup midway in the fourth period, 70-44. The loss, meanwhile, sent the ALTAs to a 1-4 slate. Only Patrick Sleat could come up with a double-digit production after the former FEU standout posted 10 points. Before this game, EAC had also frustrated defending champion Mapua University, 71-64, before pulling off a tight 75-71 escape victory against Jose Rizal University. Scores: EAC 77 - Angeles 12, Tolentino 11, Cudiamat 11, Ochavo 9, Quinal 8, Villarente 7, Shanoda 6, Dominguez 4, Bacud 3, Castillo 2, Bagay 2, Loristo 0, Oftana 0, Omandac 0. Perpetual 52 - Sleat 10, Casinillo 8, Pagulayan 6, Gojo Cruz 5, Tulabut 4, Baldoria 4, Alcantara 3, Boral 2, Duremdes 2, Gelasano 2, Nunez 2, Borja 2, Maglupay 2, Abis 2, Orgo 0, Guibao 0. Quarters: 24-11, 44-33, 63-44, 77-52. —JKC, GMA Integrated News
AU Financial Review
12-06-2025
- Business
- AU Financial Review
Seven reasons to think twice about private equity
Private markets are eating the world. That's the prevailing major structural theme in global capital markets that investors, regulators and asset managers have decided they need to accept and confront. The Australian regulator has been spooked into action to try to encourage more companies to list and reverse the shrinking sharemarket, while the country's most esteemed stock picker – Perpetual – is cutting deals with private market competitors.
GMA Network
10-06-2025
- Sport
- GMA Network
High school volleyball coach Sandy Rieta talks about handling three teams for Perpetual
By JUSTIN KENNETH CARANDANG,GMA Integrated News Many coaches are already household names in collegiate volleyball like San Sebastian College-Recoletos' Roger Gorayeb, De La Salle-College of Saint Benilde's Jerry Yee, De La Salle University's Ramil De Jesus, or National University's Dante Alinsunurin. But while he has yet to win his own title in the collegiate ranks, University of Perpetual Help System DALTA's Sandy Rieta is carving his own path as well in high school volleyball. Rieta is the head coach of three different volleyball teams in Perpetual: the women's team in collegiate, and the boys and girls team in high school. Just recently, he steered both Perpetual high school squads to the finals of the NCAA Season 100 Volleyball Fiesta with the boys' team winning the title. It was already his seventh title with the boys team. "Walang pahinga eh," Rieta told GMA News Online after winning the boys' title last Sunday. "Bukas (Monday) tryout naman, tatlong team." [No rest... Tomorrow, we're holding tryouts, three teams.] The work just never stops for Rieta, who also handled previously Alas Pilipinas players EJ Casaña, Vince Lorenzo, and Noel Kampton. Asked how he balanced handling three teams this season — and all contenders, by the way, even if the Lady Altas finished fifth this season — Rieta himself said he asks himself the same question, too. "Minsan naiisip ko na rin 'yan pag mag-isa ako eh," he said in jest. "Lalo na 'pag talo, kailangan makaisa ka para mawala 'yung [pagod]. Ayun, time management, balance." [I sometimes think about that when I'm alone... Especially after a loss, you need to get one back so that the fatigure goes away. It's time management, balance.] Handling three teams in simultaneous tournaments is no easy task. "Katulad ng season na 'to, usually umaga laro ng boys, hapon 'yung girls or alternate sila, so 'pag may laro ang college ng 2:30 p.m. or 12 p.m., magte-training ako sa umaga, usually girls sa umaga, then alis ako, pagbalik ko high school boys." [Like this season, usually the boys play in the morning, the girls in the afternoon or they alternate so when the college teams play at 2:30 p.m. or 12 p.m., I'll hold training in the morning, usually the girls in the morning then I'll leave and when I return, it's the high school boys.] The Las Piñas-based teams also have to leave the campus four hours before their scheduled game, so add to that the travel time needed on top of his training sessions and the game proper. Rieta, however, said he is just happy with what he does. "Ganun din kasi eh, 'pag nasa puso mo, 'di ka rin nakakaramdam ng pagod, 'yung passion mo, tapos masaya ka sa ginagawa mo, hindi ka makakaramdam ng pagod. Maiisip mo lang 'yung pagod 'pag talo, honestly." [It's like that, if your heart's in it, you won't feel tired, if it's your passion, and you're happy with what you're doing, you won't feel tired. You only feel the fatigue when you lose, honestly.] Good thing that Rieta won one this season and perhaps, he can now take even just a short break before starting to prepare for the next season. —JMB, GMA Integrated News
GMA Network
09-06-2025
- Sport
- GMA Network
Perpetual reclaims HS boys volleyball crown; Arellano wins first girls' trophy
By GMA Integrated News University of Perpetual Help System DALTA reclaimed the NCAA boys high school volleyball crown after outlasting Colegio de San Juan de Letran in Game 3 of the finals, 25-21, 23-25, 21-25, 25-17, 15-9, on Sunday in the NCAA Season 100 volleyball fiesta at the Filoil Centre in San Juan. John Weihanan Lat led the Junior Altas with 15 attacks, six blocks, and an ace, while Zyro Ornos had 19 points. Team captain Charles Conciina distributed the ball well with 19 excellent sets, while Nathan Paul Ciriaco and Gabriel Cyrus Macatumo had 16 points. Resty Santos had 12 points. Jessel Nimo had 22 points, while Nhasty Bajaladia had 18 points for the Squires. This is Perpetual's 13th title in high school volleyball, and according to head coach Sandy Rita is his seventh under his belt. 'Para sa amin talaga,' Rieta told GMA News Online. 'Medyo may gigil din sa sarili ko, siyempre kailangan kong maibalik. Confident din ako ngayon na aabot sa finals 'yung players ko.' [It was really for us... I had some eagerness also myself, of course I wanted to get it back. I'm also confident now that my players are in the finals.] In the girls' division, Arellano University claimed its first title after beating Perpetual in Game 2 of the finals last May 31, 21-25, 15-25, 25-16, 25-11, 15-4. Samantha Maranan erupted fof 31 points from 30 attacks and an ace, while Catherine Cau and Jasmine Galaga had 19 and 14 points, respectively. Sherrie Rose Acosta was the only double-digit scorer for Perpetual with 20 points. ?'First time namin eh and lahat kami nagtulungan so worth it naman lahat,' Maranan said. [It was our first time and we all helped each other and it was all worth it.] —Justin Kenneth Carandang/JMB, GMA Integrated News
