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Can Pregnancy Up the Risk for Recurrent CeAD, Stroke?
Can Pregnancy Up the Risk for Recurrent CeAD, Stroke?

Medscape

time31-07-2025

  • Health
  • Medscape

Can Pregnancy Up the Risk for Recurrent CeAD, Stroke?

TOPLINE: Pregnancy was not associated with an increased risk for recurrent cervical artery dissection (CeAD), stroke, or death up to 5 years later in women with a history of CeAD, a new cohort study showed. METHODOLOGY: Researchers conducted a registry-based, explorative cohort study across 33 stroke centers in nine countries using data collected between 1990 and 2023. 1013 women with a history of CeAD (median age, 42 years) and at least 6 months of follow-up data were included. Of these, 114 became pregnant during the study (pregnancy group), and 899 did not (nonpregnancy group). The primary outcome was a composite of recurrent CeAD, stroke of any type, and all-cause mortality. Secondary outcomes were individual components of the composite outcome. The median follow-up duration was 5.3 years, and the analysis was adjusted for age. TAKEAWAY: The composite outcome was observed in 9% of the pregnancy group, including seven cases of recurrent CeAD, two of ischemic stroke, and one of intracerebral hemorrhage (ICH), vs 7% of the nonpregnancy group, which included 32 cases of recurrent CeAD, 26 of ischemic stroke, four of ICH, and five of death (adjusted hazard ratio [aHR], 0.77; 95% CI, 0.38-1.56). Five of the 10 primary outcome events in the pregnancy group occurred during the postpartum period, suggesting increased vulnerability during this phase. Secondary outcomes also showed no significant between-group differences in risk for recurrent CeAD (aHR, 1.0), ischemic stroke (aHR, 0.5), and ICH (aHR, 1.0). The incidence rate of recurrent CeAD was 0.7% per patient-year in the pregnancy group vs 0.5% per patient-year in the nonpregnancy group. IN PRACTICE: 'These findings suggest that pregnancy is not associated with an increased risk of subsequent events; therefore, prior CeAD does not justify advising against future pregnancy,' the investigators wrote, adding that the results 'may be helpful for individual counseling and family planning for women with prior CeAD.' SOURCE: This study was led by Sandro K. Fischer, MMed, University Hospital Basel, Basel, Switzerland. It was published online on July 17 in JAMA Network Open. LIMITATIONS: This study was limited by its exploratory nature, potential referral bias, underrepresentation of women at a higher presumed recurrence risk in the pregnancy group, and a lack of central data monitoring and adjudication of diagnoses, exposure variables, and outcome events. Additionally, the small number of events may have led to statistical imprecision. DISCLOSURES: This study was funded by the Swiss Heart Foundation and the Associazione per la Lotta alla Trombosi e alle Malattie Cardiovascolari. Several investigators reported having financial ties with various sources, including pharmaceutical companies. Some investigators also reported holding industry‐related patents and having employment or advisory ties with pharmaceutical companies outside the submitted work. Details are fully listed in the original article. This article was created using several editorial tools, including AI, as part of the process. Human editors reviewed this content before publication.

The Rise of Mini Minimalism: SHEIN's Kidswear Embraces Comfort with Soft and Breathable Materials
The Rise of Mini Minimalism: SHEIN's Kidswear Embraces Comfort with Soft and Breathable Materials

Business Upturn

time17-07-2025

  • Entertainment
  • Business Upturn

The Rise of Mini Minimalism: SHEIN's Kidswear Embraces Comfort with Soft and Breathable Materials

SYDNEY, July 17, 2025 (GLOBE NEWSWIRE) — A new wave of parenting style is emerging – one that values simplicity, quality, and comfort over clutter and chaos. In response, global fashion and lifestyle leader SHEIN unveils its latest offering: Mini Style , a refined range of baby, toddler, and maternity wear designed to make everyday family dressing feel effortless. SHEIN recently brought Mini Style to life at the Pregnancy, Babies & Children's Expo (PBC Expo) in Melbourne with an immersive showroom activation. The interactive space offered expo-goers a chance to experience the range first-hand, showcasing the brand's commitment to comfort, quality, and design through a curated display of key looks across baby, toddler, and maternity wear. Styled around everyday parenting moments, from daycare drop-offs to birthday celebrations, the activation provided a tactile and visual introduction to Mini Style's thoughtful approach to modern family dressing. With an emphasis on fabric-first design and comfort-driven details, Mini Style brings a new sensibility to kidswear. The collection features a wide selection of garments made from material choices that are breathable and soft to the touch – aligning with the growing demand for clothing that supports both form and function. ' Parents today are seeking styles that work harder – feels good, washes well, and suits every stage of childhood, ' said a SHEIN spokesperson. ' Mini Style is about celebrating the practical, without compromising on personality. ' From playtime to party mode, Mini Style's offering is built around real-life needs. Expect neutral-toned staples, stretchy silhouettes, and elevated basics that are easy to mix, match, and layer – whether you're navigating daycare drop-off or packing for a family weekend away. From onesies that are soft on the skin and stretchy everyday sets to adorable occasion-wear, the collection is designed for real moments – and real mess. Whether it's a kindy drop-off, a long-haul flight, or the all-important birthday party, Mini Style has parents covered with neutral-toned basics, travel-ready layers, and photo-perfect celebration outfits that combine comfort and character in equal measure. Mini Style also extends into maternity and nursing-friendly styles, supporting parents with thoughtfully constructed fits for all-day comfort and versatility during pregnancy and beyond. Available now at , customers can enjoy 20% off orders over $39 AUD using the exclusive code MINISTYLE. Media contact: [email protected], +61 7 3556 7756, +61 2 9059 2502 Disclaimer: The above press release comes to you under an arrangement with GlobeNewswire. Business Upturn takes no editorial responsibility for the same. Ahmedabad Plane Crash

Health Matters Newsletter: Safeguarding the windows to the soul
Health Matters Newsletter: Safeguarding the windows to the soul

The Hindu

time24-06-2025

  • Health
  • The Hindu

Health Matters Newsletter: Safeguarding the windows to the soul

On cataract surgeries and the urgent need for access, brain and spine innovations, maternal health amidst rising heat, sickle cell care and more It's one of the most common surgeries performed, a procedure that practically everyone has heard of and perhaps one that most of us will have to undergo, but cataract surgeries are still not available and accessible to all -- cataracts continue to account for about 40% of all cases of existing blindness, and in India, remain the leading cause of blindness. In fact, as of 2023, the World Health Organization estimated that only 17% of people with vision impairment due to cataract have received access to an appropriate intervention. This, despite the surgery being one of the safest and least resource-intensive of procedures. We take our vision for granted most times, never really thinking about our eyes or how they work despite their being crucial to every aspect of our lives, but this June, observed as Cataract Awareness Month, is as good time a time as any, to learn and understand more about them. And to this end, we have two stories on cataract for you: Dr. S. Soundari explains the hows and whys of cataracts and the surgery required, and Dr. C. Aravinda and Dr. Sangeetha Raja give you a glimpse of the history and the evolution of the procedure that is now used to treat millions. Speaking of surgeries, here are a few more stories of interest, delving into medical procedures for the brain and spine: Dr. Ari G. Chacko explores advances in brain tumour care, while Dr. G. Sudhir and Dr. K. Karthik Kailash explain how minimally invasive spine surgery has transformed the landscape of spinal care. But in all of the excitement over the latest in medical science, the progress in technology and the potential promise of AI, it is crucial to not forget the basics: ensuring the health of mother and baby. And not only are we still some distance away from achieving optimal care for all mothers and babies in India, climate change is now emerging as an increased threat to the health of both. Take this into consideration: despite overall progress over the last 30 years, an analysis (published in the British Medical Journal Global Health) has found that cases of low weight at birth from four states -- Uttar Pradesh, Bihar, Maharashtra, and West Bengal -- account for nearly half of India's cases. Having a low birth weight -- under 2.5 kg -- has been linked with problems in the child's cognitive development and a vulnerability to chronic conditions in later life. To add to this existing issue is the burden of extreme heat: I podcast with Prof Jane Hirst about how high temperatures -- which India now faces on a regular basis -- impact pregnancy outcomes. Talking of maternal health, C. Mayareports that Kerala still has the lowest maternal mortality ratio (MMR) in the country despite some latest data revealing figures that the State disputes. And in Tamil Nadu, P. V. Srividya writes, the government's Pregnancy and Infant Cohort Monitoring and Evaluation system has helped exposechild marriages. Maternal health isn't just crucial at the time of pregnancy: Athira Elssa Johnsondecodes a study that found that domestic violence perpetrated on mothers was linked with higher depressive disorders amongst their teen children, highlighting again, the vital need to safeguard the health of mothers -- as this is intrinsically linked with the health of the next generation. One more story on newborns that can have far-reaching implication if made into policy is this study by the Indian Council of Medical Research that found post-birth diagnosis, resulting in early treatment, could substantially improve the quality of life and reduce mortality in patients with sickle cell disease -- from the reported current 20 to 30% to less than 5%. If you're wondering what sickle cell disease is, do read this explainer. Internationally too, there's been some focus on this area: British lawmakers have debated proposals to decriminalise abortion amid concerns that police are using antiquated laws to prosecute women who end their own pregnancies. Elsewhere around the globe, there's some good news, the United States' Food and Drug Administration (FDA) has approved of pharma company Gilead Sciences' twice-yearly injection to prevent HIV -- a move the company hailed as a major breakthrough in the fight against the sexually transmitted virus. Lenacapavir, marketed under the brand name Yeztugo, has been shown to reduce the risk of HIV transmission by more than 99.9 percent in adults and adolescents -- making it functionally akin to a powerful vaccine. Local news however, has been good, and not-so-good: while R. Prasadwrites on two existing drugs that offer hope to cure Russell's viper bites; Moyurie Som reports on the West Bengal Assembly passing a Bill on 'transparency' in medical costs in private facilities and Abhinay Lakshman details the Centre's plans to set up a National Tribal Health and Research Institute, Afshan Yasmeen speaks to the corresponding author of a research paper that has found that public health spending has not resulted in significant pro-poor services in India and S. Vijay Kumar finds that a report released by the Union Ministry of Health and Family Welfare has revealed that the organ transplantation programme in the country has been crippled by multiple issues, especially insufficient funding, shortage of specialised doctors, and procedural delays. Here's a quick round-up of the Covid-19 situation: cases are dipping, despite social media buzz about the 'razor blade' Covid variant, but even so, the ICMR has introduced its first high-performance computing facility at its National Institute of Virology (NIV) facility in Pune to boost genomic storage and analysis, aiding faster detection of new disease threats and more efficient response to outbreaks. Our tailpiece for the week is this story by Dr. Vid Karmarkar and Jitendra Chouksey on why alcohol regulation in India needs a national framework and policy. Once again, we have a healthy list of explainers this week, do dive in when you find the time: Dr. Arunima Ray writes on understanding albinism in the Indian context Dr. Javeed Zabiullah explains why the world needs to embrace neurodiversity Dr. V. Madhumitha busts myths around vitiligo Dr. Raman Goel writes on the importance of changing mindsets and narratives around obesity Dr. Arun Kumar Balakrishnan details the need to screen for kidney cancer after 40 Anirban Mukhopadhyay breaks down a study on making CAR T-cells in vivo for cancer care If you want to know about DNA analysis, click here As part of our 'all you need to know' series, here is an explainer on the world's rarest blood group, Gwada negative, and one on clinical trials And finally, here is why chronic pain must be part of suicide risk assessments For many more health stories, head to our health page and subscribe to the health newsletter here.

Safeguarding the windows to the soul
Safeguarding the windows to the soul

The Hindu

time24-06-2025

  • Health
  • The Hindu

Safeguarding the windows to the soul

On cataract surgeries and the urgent need for access, brain and spine innovations, maternal health amidst rising heat, sickle cell care and more It's one of the most common surgeries performed, a procedure that practically everyone has heard of and perhaps one that most of us will have to undergo, but cataract surgeries are still not available and accessible to all -- cataracts continue to account for about 40% of all cases of existing blindness, and in India, remain the leading cause of blindness. In fact, as of 2023, the World Health Organization estimated that only 17% of people with vision impairment due to cataract have received access to an appropriate intervention. This, despite the surgery being one of the safest and least resource-intensive of procedures. We take our vision for granted most times, never really thinking about our eyes or how they work despite their being crucial to every aspect of our lives, but this June, observed as Cataract Awareness Month, is as good time a time as any, to learn and understand more about them. And to this end, we have two stories on cataract for you: Dr. S. Soundari explains the hows and whys of cataracts and the surgery required, and Dr. C. Aravinda and Dr. Sangeetha Raja give you a glimpse of the history and the evolution of the procedure that is now used to treat millions. Speaking of surgeries, here are a few more stories of interest, delving into medical procedures for the brain and spine: Dr. Ari G. Chacko explores advances in brain tumour care, while Dr. G. Sudhir and Dr. K. Karthik Kailash explain how minimally invasive spine surgery has transformed the landscape of spinal care. But in all of the excitement over the latest in medical science, the progress in technology and the potential promise of AI, it is crucial to not forget the basics: ensuring the health of mother and baby. And not only are we still some distance away from achieving optimal care for all mothers and babies in India, climate change is now emerging as an increased threat to the health of both. Take this into consideration: despite overall progress over the last 30 years, an analysis (published in the British Medical Journal Global Health) has found that cases of low weight at birth from four states -- Uttar Pradesh, Bihar, Maharashtra, and West Bengal -- account for nearly half of India's cases. Having a low birth weight -- under 2.5 kg -- has been linked with problems in the child's cognitive development and a vulnerability to chronic conditions in later life. To add to this existing issue is the burden of extreme heat: I podcast with Prof Jane Hirst about how high temperatures -- which India now faces on a regular basis -- impact pregnancy outcomes. Talking of maternal health, C. Mayareports that Kerala still has the lowest maternal mortality ratio (MMR) in the country despite some latest data revealing figures that the State disputes. And in Tamil Nadu, P. V. Srividya writes, the government's Pregnancy and Infant Cohort Monitoring and Evaluation system has helped exposechild marriages. Maternal health isn't just crucial at the time of pregnancy: Athira Elssa Johnsondecodes a study that found that domestic violence perpetrated on mothers was linked with higher depressive disorders amongst their teen children, highlighting again, the vital need to safeguard the health of mothers -- as this is intrinsically linked with the health of the next generation. One more story on newborns that can have far-reaching implication if made into policy is this study by the Indian Council of Medical Research that found post-birth diagnosis, resulting in early treatment, could substantially improve the quality of life and reduce mortality in patients with sickle cell disease -- from the reported current 20 to 30% to less than 5%. If you're wondering what sickle cell disease is, do read this explainer. Internationally too, there's been some focus on this area: British lawmakers have debated proposals to decriminalise abortion amid concerns that police are using antiquated laws to prosecute women who end their own pregnancies. Elsewhere around the globe, there's some good news, the United States' Food and Drug Administration (FDA) has approved of pharma company Gilead Sciences' twice-yearly injection to prevent HIV -- a move the company hailed as a major breakthrough in the fight against the sexually transmitted virus. Lenacapavir, marketed under the brand name Yeztugo, has been shown to reduce the risk of HIV transmission by more than 99.9 percent in adults and adolescents -- making it functionally akin to a powerful vaccine. Local news however, has been good, and not-so-good: while R. Prasadwrites on two existing drugs that offer hope to cure Russell's viper bites; Moyurie Som reports on the West Bengal Assembly passing a Bill on 'transparency' in medical costs in private facilities and Abhinay Lakshman details the Centre's plans to set up a National Tribal Health and Research Institute, Afshan Yasmeen speaks to the corresponding author of a research paper that has found that public health spending has not resulted in significant pro-poor services in India and S. Vijay Kumar finds that a report released by the Union Ministry of Health and Family Welfare has revealed that the organ transplantation programme in the country has been crippled by multiple issues, especially insufficient funding, shortage of specialised doctors, and procedural delays. Here's a quick round-up of the Covid-19 situation: cases are dipping, despite social media buzz about the 'razor blade' Covid variant, but even so, the ICMR has introduced its first high-performance computing facility at its National Institute of Virology (NIV) facility in Pune to boost genomic storage and analysis, aiding faster detection of new disease threats and more efficient response to outbreaks. Our tailpiece for the week is this story by Dr. Vid Karmarkar and Jitendra Chouksey on why alcohol regulation in India needs a national framework and policy. Once again, we have a healthy list of explainers this week, do dive in when you find the time: Dr. Arunima Ray writes on understanding albinism in the Indian context Dr. Javeed Zabiullah explains why the world needs to embrace neurodiversity Dr. V. Madhumitha busts myths around vitiligo Dr. Raman Goel writes on the importance of changing mindsets and narratives around obesity Dr. Arun Kumar Balakrishnan details the need to screen for kidney cancer after 40 Anirban Mukhopadhyay breaks down a study on making CAR T-cells in vivo for cancer care If you want to know about DNA analysis, click here As part of our 'all you need to know' series, here is an explainer on the world's rarest blood group, Gwada negative, and one on clinical trials And finally, here is why chronic pain must be part of suicide risk assessments For many more health stories, head to our health page and subscribe to the health newsletter here.

Tom Cruise's co-star reveals she was eight months pregnant when she shot Mission: Impossible fight scene
Tom Cruise's co-star reveals she was eight months pregnant when she shot Mission: Impossible fight scene

Daily Mail​

time24-05-2025

  • Entertainment
  • Daily Mail​

Tom Cruise's co-star reveals she was eight months pregnant when she shot Mission: Impossible fight scene

Hayley Atwell appeared on The Tonight Show Starring Jimmy Fallon this week, where she opened up about filming Mission: Impossible – The Final Reckoning. While on the late night show, the 43-year-old actress, who starred in the movie alongside Tom Cruise, detailed her experience working while pregnant. Asked if there was anything she wanted to share before the audience was shown a snippet from the feature film, she revealed, 'During this fight sequence — we came back to it a few times to add a few elements to it. And in this clip, I'm actually eight-and-a-half months pregnant.' Atwell noted that she'd never shared the fact before, calling it 'a Fallon exclusive.' She went on to say, 'I was taken such good care of. Everyone was so supportive and they were like, "Oh, you can sit down, and we'll have a stunt double do it." And I was like, "No! I've worked too hard. Let me do it." So I did it, and here it is.' From A-list scandals and red carpet mishaps to exclusive pictures and viral moments, subscribe to the DailyMail's new Showbiz newsletter to stay in the loop. While on the late night show, the 43-year-old actress, who starred in the movie alongside Tom Cruise , detailed her experience working while pregnant Mission: Impossible – The Final Reckoning is the beloved franchise's eighth and final iteration, after first hitting the silver screen in 1996. Atwell made her initial appearance in the franchise as IMF agent Grace in 2023. The star gave birth to her first child with her music producer beau Ned Wolfgang Kelly last year. The couple got engaged in April 2023, with Kelly gushing on Instagram at the time, 'I'd never had any interest in getting married… until I met this extraordinary woman.' Sharing a photo of them side-by-side while the actress flashed her glinting diamond ring, he wrote, 'Lucky me. Arrived in Venice at 10am. 'Around midday the love of my life and I got engaged in the kitchen of this strange apartment full of porcelain ducks, with a bloke outside the window murdering 'My Way' on the accordion. A perfect start to the rest of our lives together.' The British entertainer explained to Daily Mail that year, 'We had rented this Airbnb that had lots of shelves with porcelain ducks on them, so it was quite a surreal setup. 'My fiancé was in his [underwear] in the kitchen, and there was an accordion playing outside our window — which was timed perfectly but not planned,' she confirmed. Hayley seemingly confirmed that the two have tied the knot in a May 19 episode of LIVE with Kelly and Mark as she referred to the musician as her husband. The beauty regularly appears on his Instagram account, where he engages a modest audience of about 4,000 followers. He's currently by her side in Cannes, France, supporting her at the Cannes Film Festival, which wraps on Saturday. Taking to Instagram Stories on Friday he shared a video of the siren walking the red carpet in a midriff-baring black black top and coordinating long skirt. Ned wrote, 'Go watch my amazing wife killing it in The Final Reckoning. The film absolutely rocks.'

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