Latest news with #QuantumBioPharmaLtd
Toronto Star
5 days ago
- Business
- Toronto Star
Quantum BioPharma Signs Agreement to Manufacture Oral Drug Formulation of its Potential Breakthrough Drug Lucid-21-302 (Lucid-MS) for Use in its Upcoming Phase 2 Multiple Sclerosis Trial
TORONTO, Aug. 11, 2025 (GLOBE NEWSWIRE) — Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) (Upstream: QNTM) ('Quantum BioPharma' or the 'Company'), a biopharmaceutical company dedicated to innovative therapies for neurodegenerative disorders, today announces through its subsidiary, Huge Biopharma Australia Pty Ltd., that it has signed an agreement with a leading contract development and manufacturing organization (CDMO) to manufacture an oral drug formulation of Lucid-MS. The oral formulation of Lucid-MS will serve as the drug product for the Company's Phase 2 clinical trial, which will test the efficacy on humans of Lucid-MS as a possible treatment for people to gain back mobility lost with multiple sclerosis (MS). To date numerous animal models over the past decade showed Lucid-MS helped those animals regain their ability to walk. Videos can be seen at Lucid-MS is a first-in-class, non-immunomodulatory, neuroprotective compound with a unique mechanism of action for the treatment of MS. It is a patented New Chemical Entity (NCE) that has been shown in preclinical models to prevent demyelination, which is a hallmark of MS and other neurogenerative diseases and is characterized by damage to the myelin sheath surrounding nerve fibers.
Toronto Star
08-08-2025
- Business
- Toronto Star
Quantum BioPharma Announces Very Promising Results from the Massachusetts General Hospital Scientists on the Novel Positron Emission Tomography (PET) Tracer Used to Detect and Monitor Demyelination in Multiple Sclerosis Patients
TORONTO, Aug. 08, 2025 (GLOBE NEWSWIRE) — Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) ('Quantum BioPharma' or the 'Company'), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions, announces that the Positron Emission Tomography (PET) tracer used in a joint study with Massachusetts General Hospital (MGH) scientists shows the ability to capture differences across lesions in multiple sclerosis (MS) patients, which may prove highly useful for monitoring myelin integrity and demyelination in MS. A leading study by Drs. Pedro Brugarolas and Eric Klawiter of MGH, published in the European Journal of Nuclear Medicine and Molecular Imaging on August 5, 2025 (link to paper: and funded by the National Institutes of Health (NIH), evaluated the PET tracer [18F]3F4AP in healthy controls and in people with MS. This tracer was developed by Dr. Pedro Brugarolas, an investigator in the Department of Radiology at MGH and Assistant Professor at Harvard Medical School. In this study, [18F]3F4AP was found to have excellent properties for imaging the human brain and, critically and importantly, was able to detect differences across lesions not visible by conventional MRI. These findings suggest that the tracer holds significant promise and potential as a key biomarker to monitor changes in demyelination in MS, and, importantly, myelin changes in response to Quantum Biopharma's investigational and potentially breakthrough neuroprotective drug, Lucid-21-302. ARTICLE CONTINUES BELOW 'The published study shows that the PET tracer is highly promising as a biomarker to detect and monitor lesions in people with MS,' said Dr. Andrzej Chruscinski, Vice-President, Scientific and Clinical Affairs at Quantum Biopharma. 'The ongoing collaborative study with MGH seeks to further evaluate the imaging agent and its potential to demonstrate the effectiveness of drugs, such as Lucid-21-302 (Lucid-MS) that can protect the myelin sheath in MS.' About Quantum BioPharma Ltd. Quantum BioPharma (NASDAQ: QNTM) is a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions for the treatment of challenging neurodegenerative and metabolic disorders and alcohol misuse disorders with drug candidates in different stages of development. Through its wholly owned subsidiary, Lucid Psycheceuticals Inc. ('Lucid'), Quantum BioPharma is focused on the research and development of its lead compound, Lucid-MS. Lucid-MS is a patented new chemical entity shown to prevent and reverse myelin degradation, the underlying mechanism of multiple sclerosis, in preclinical models. Quantum BioPharma invented unbuzzd™ and spun out its OTC version to a company, Celly Nutrition Corp. ('Celly Nutrition'), now Unbuzzd Wellness Inc., led by industry veterans. Quantum BioPharma retains ownership of 20.10% (as of June 30, 2025) of Unbuzzd Wellness Inc. at The agreement with Unbuzzd Wellness Inc. also includes royalty payments of 7% of sales from unbuzzd™ until payments to Quantum BioPharma total $250 million. Once $250 million is reached, the royalty drops to 3% in perpetuity. Quantum BioPharma retains 100% of the rights to develop similar products or alternative formulations specifically for pharmaceutical and medical uses. Quantum BioPharma maintains a portfolio of strategic investments through its wholly owned subsidiary, FSD Strategic Investments Inc., which represents loans secured by residential or commercial property. For more information visit Forward Looking Information These statements involve known and unknown risks, uncertainties and other factors, which may cause actual results, performance or achievements to differ materially from those expressed or implied by such statements, including but not limited to additional information relating to Quantum BioPharma, including its annual information form, can be located on the SEDAR+ website at and on the EDGAR section of the United States Securities and Exchange Commission's website at for a more complete discussion of such risk factors and their potential effects. Readers are cautioned that the foregoing list is not exhaustive. Readers are further cautioned not to place undue reliance on forward-looking statements, as there can be no assurance that the plans, intentions or expectations upon which they are placed will occur. Such information, although considered reasonable by management at the time of preparation, may prove to be incorrect and actual results may differ materially from those anticipated. Forward-looking statements contained in this press release are expressly qualified by this cautionary statement and reflect the Company's expectations as of the date hereof and are subject to change thereafter. The Company undertakes no obligation to update or revise any forward-looking statements, whether as a result of new information, estimates or opinions, future events or results or otherwise or to explain any material difference between subsequent actual events and such forward- looking information, except as required by applicable law. Contacts: Quantum BioPharma Ltd. Zeeshan Saeed, Founder, CEO and Executive Co-Chairman of the Board Email: Zsaeed@ Telephone: (833) 571-1811 Investor Relations Investor Relations: IR@ General Inquiries: info@
Toronto Star
07-08-2025
- Business
- Toronto Star
Quantum Biopharma Reports Strong Second Quarter with Increased Current and Total Assets, Conversion of all Debentures into Equity, Continued Exclusion of Going Concern, Tripling of Share Price during Quarter, over $500,000 USD Gain in Crypto Assets as of date of filing, and Near Elimination of Debt
TORONTO, Aug. 07, 2025 (GLOBE NEWSWIRE) — Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91) ('Quantum BioPharma' or the 'Company'), is pleased to announce its financial and operational results for the second quarter ending June 30, 2025. Overall, the Company is in a strong position having increased its current and total assets, compared to the previous quarter; eliminated the entire debt liability associated with debentures issued in Q4 2024 and Q1 2025 by converting all debentures into equity; maintained its 'no going concern' status; seen greater than $500,000 USD appreciation in the value of its cryptocurrency reserves as of date of filing; and seen its stock price almost tripled from $7.71 USD at Q1 close March 31, 2025 to $20.25 USD at Q2 close June 30, 2025. Management believes that there is sufficient cash on hand to maintain basic operations beyond March 2027.
Yahoo
02-06-2025
- Business
- Yahoo
iNGENū CRO Partners with Quantum BioPharma to Launch Pioneering Australian Clinical Trial for Chronic Nociplastic Pain in MCAS Patients
Study Aims to Expedite Potentially Transformative Therapies By Assessing Safety and Efficacy of FSD202 Melbourne, Australia, June 02, 2025 (GLOBE NEWSWIRE) -- iNGENū CRO, a leading full-service Contract Research Organization (CRO) in the Asia-Pacific region, is proud to announce its operational leadership role in a Phase 2 clinical trial launched in partnership with Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions. The study targets chronic widespread nociplastic pain associated with idiopathic Mast Cell Activation Syndrome/Disorder (MCAS/MCAD)—a debilitating and under-recognized condition. The cause of MCAS is unknown and there currently is no cure. The randomized, double-blind, placebo-controlled, parallel-group study will be conducted across high-performing clinical sites in Australia, with regulatory oversight by the Therapeutic Goods Administration (TGA) and relevant Human Research Ethics Committees (HREC). iNGENū CRO is managing full trial execution including protocol refinement, regulatory and ethics submissions, site activation, clinical monitoring, and data management. 'This study is a testament to what can be achieved when operational excellence and scientific innovation come together,' said Dr. Sud Agarwal, Chief Medical Officer of iNGENū CRO. 'Patients with MCAS-related nociplastic pain often have no effective treatment options. By designing and operationalizing this trial in Australia, iNGENū CRO is helping to fast-track potentially transformative therapies through the clinical development pipeline.' The investigational therapy being studied is intended to target the neuroimmune pathways implicated in both mast cell dysregulation and centrally mediated pain processing. Primary and secondary endpoints will assess changes in patient-reported pain, global functioning, safety, and biomarker response. FSD202, an investigational drug containing ultra-micronized palmitoylethanolamide (PEA), shows promise in treating a broad spectrum of inflammatory diseases, including MCAS/MCAD. This potential is especially significant given that chronic inflammatory conditions are the leading cause of death worldwide. About Quantum BioPharma Ltd. Quantum BioPharma (NASDAQ: QNTM) is a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions for the treatment of challenging neurodegenerative and metabolic disorders and alcohol misuse disorders with drug candidates in different stages of development. Through its wholly owned subsidiary, Lucid Psycheceuticals Inc. (' Lucid '), Quantum BioPharma is focused on the research and development of its lead compound, Lucid-MS. Lucid-MS is a patented new chemical entity shown to prevent and reverse myelin degradation, the underlying mechanism of multiple sclerosis, in preclinical models. Quantum BioPharma invented unbuzzd™ and spun out its OTC version to a company, Celly Nutrition Corp. ('Celly Nutrition'), led by industry veterans. Quantum BioPharma retains ownership of 22.95% (as of December 31, 2024) of Celly Nutrition at The agreement with Celly Nutrition also includes royalty payments of 7% of sales from unbuzzd™ until payments to Quantum BioPharma total $250 million. Once $250 million is reached, the royalty drops to 3% in perpetuity. Quantum BioPharma retains 100% of the rights to develop similar products or alternative formulations specifically for pharmaceutical and medical uses. Quantum BioPharma maintains a portfolio of strategic investments through its wholly owned subsidiary, FSD Strategic Investments Inc., which represents loans secured by residential or commercial property. For more information on Quantum BioPharma, please visit About iNGENū CRO iNGENū CRO is a globally active, Asia-Pacific-headquartered Contract Research Organization supporting biotech and pharmaceutical clients with end-to-end clinical trial solutions. Specializing in complex, multinational trials and innovative therapeutic areas, INGENU delivers regulatory, operational, and technological excellence across Australia, Malaysia, Singapore, and the UK. For more information on iNGENū CRO, please visit Media Contact: iNGENū CRO Amanda De Vito Global Head of Sales and Marketing Email: Quantum BioPharma Zeeshan SaeedFounder, CEO and Executive Co-Chairman of the BoardEmail: zsaeed@ CONTACT: Name: Amanda De Vito Email: Job Title: Global Head of Sales and MarketingError in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
02-06-2025
- Business
- Yahoo
iNGENū CRO Partners with Quantum BioPharma to Launch Pioneering Australian Clinical Trial for Chronic Nociplastic Pain in MCAS Patients
Study Aims to Expedite Potentially Transformative Therapies By Assessing Safety and Efficacy of FSD202 Melbourne, Australia, June 02, 2025 (GLOBE NEWSWIRE) -- iNGENū CRO, a leading full-service Contract Research Organization (CRO) in the Asia-Pacific region, is proud to announce its operational leadership role in a Phase 2 clinical trial launched in partnership with Quantum BioPharma Ltd. (NASDAQ: QNTM) (CSE: QNTM) (FRA: 0K91), a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions. The study targets chronic widespread nociplastic pain associated with idiopathic Mast Cell Activation Syndrome/Disorder (MCAS/MCAD)—a debilitating and under-recognized condition. The cause of MCAS is unknown and there currently is no cure. The randomized, double-blind, placebo-controlled, parallel-group study will be conducted across high-performing clinical sites in Australia, with regulatory oversight by the Therapeutic Goods Administration (TGA) and relevant Human Research Ethics Committees (HREC). iNGENū CRO is managing full trial execution including protocol refinement, regulatory and ethics submissions, site activation, clinical monitoring, and data management. 'This study is a testament to what can be achieved when operational excellence and scientific innovation come together,' said Dr. Sud Agarwal, Chief Medical Officer of iNGENū CRO. 'Patients with MCAS-related nociplastic pain often have no effective treatment options. By designing and operationalizing this trial in Australia, iNGENū CRO is helping to fast-track potentially transformative therapies through the clinical development pipeline.' The investigational therapy being studied is intended to target the neuroimmune pathways implicated in both mast cell dysregulation and centrally mediated pain processing. Primary and secondary endpoints will assess changes in patient-reported pain, global functioning, safety, and biomarker response. FSD202, an investigational drug containing ultra-micronized palmitoylethanolamide (PEA), shows promise in treating a broad spectrum of inflammatory diseases, including MCAS/MCAD. This potential is especially significant given that chronic inflammatory conditions are the leading cause of death worldwide. About Quantum BioPharma Ltd. Quantum BioPharma (NASDAQ: QNTM) is a biopharmaceutical company dedicated to building a portfolio of innovative assets and biotech solutions for the treatment of challenging neurodegenerative and metabolic disorders and alcohol misuse disorders with drug candidates in different stages of development. Through its wholly owned subsidiary, Lucid Psycheceuticals Inc. (' Lucid '), Quantum BioPharma is focused on the research and development of its lead compound, Lucid-MS. Lucid-MS is a patented new chemical entity shown to prevent and reverse myelin degradation, the underlying mechanism of multiple sclerosis, in preclinical models. Quantum BioPharma invented unbuzzd™ and spun out its OTC version to a company, Celly Nutrition Corp. ('Celly Nutrition'), led by industry veterans. Quantum BioPharma retains ownership of 22.95% (as of December 31, 2024) of Celly Nutrition at The agreement with Celly Nutrition also includes royalty payments of 7% of sales from unbuzzd™ until payments to Quantum BioPharma total $250 million. Once $250 million is reached, the royalty drops to 3% in perpetuity. Quantum BioPharma retains 100% of the rights to develop similar products or alternative formulations specifically for pharmaceutical and medical uses. Quantum BioPharma maintains a portfolio of strategic investments through its wholly owned subsidiary, FSD Strategic Investments Inc., which represents loans secured by residential or commercial property. For more information on Quantum BioPharma, please visit About iNGENū CRO iNGENū CRO is a globally active, Asia-Pacific-headquartered Contract Research Organization supporting biotech and pharmaceutical clients with end-to-end clinical trial solutions. Specializing in complex, multinational trials and innovative therapeutic areas, INGENU delivers regulatory, operational, and technological excellence across Australia, Malaysia, Singapore, and the UK. For more information on iNGENū CRO, please visit Media Contact: iNGENū CRO Amanda De Vito Global Head of Sales and Marketing Email: Quantum BioPharma Zeeshan SaeedFounder, CEO and Executive Co-Chairman of the BoardEmail: zsaeed@ CONTACT: Name: Amanda De Vito Email: Job Title: Global Head of Sales and MarketingSign in to access your portfolio
