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Researchers at Long Island lab discover breakthrough that slows pancreatic cancer progression
Researchers at Long Island lab discover breakthrough that slows pancreatic cancer progression

Yahoo

time10-04-2025

  • Health
  • Yahoo

Researchers at Long Island lab discover breakthrough that slows pancreatic cancer progression

The Brief Pancreatic cancer is predicted to become the second-deadliest cancer in the US by 2030. Researchers at the Cold Spring Harbor Laboratory have found a way to slow the progression of pancreatic cancer during its early stages. The method blocks two proteins known to make the cancer become malignant. Researchers on Long Island have discovered a breakthrough that could aid in the mission to help maintain and possibly cure one of the most deadly forms of cancer in the United States. Dig deeper Cold Spring Harbor Laboratory (CSHL) has found a way to prevent the progression of cancer cells by blocking two proteins known as FGFR2 and EGFR. Claudia Tonelli, a research investigator at CSHL, spent countless hours studying early versions of pancreatic cancer in mice and lab grown versions of human pancreatic tissue. What they're saying "These two proteins, together, can make the cells become malignant," Tonelli told FOX 5 New York. Local perspective Bill Reindl, 68, was diagnosed with stage 4 pancreatic cancer last summer. Reindl will have to undergo chemotherapy for the rest of his life to treat the disease. What they're saying "Like probably most people I was in denial for a little while - this couldn't be possible," Reindl told FOX 5. But news of CSHL's breakthrough gives both Reindl and his family hope. "It's a golden ticket, a second chance," Amy Pollaci, Reindl's daughter, said. Researchers at CSHL predict pancreatic cancer will become the second-deadliest cancer in America by 2030. Pancreatic cancer is often not found and diagnosed until it is in its later stages, according to the American Cancer Association. "The pancreas is deep inside the body, so early tumors can't be seen or felt by health care providers during routine physical exams. People usually have no symptoms until the cancer has become very large or has already spread to other organs," the ACA website states. The Source Information for this article was taken from local reporting by FOX 5 New York's Jodi Goldberg and interviews with the Cold Spring Harbor Laboratory.

Germany's Renk forecasts 2025 growth backed by 5 billion euro order book
Germany's Renk forecasts 2025 growth backed by 5 billion euro order book

Reuters

time26-03-2025

  • Automotive
  • Reuters

Germany's Renk forecasts 2025 growth backed by 5 billion euro order book

March 26 (Reuters) - German tank gearbox maker Renk ( opens new tab expects its strong order backlog to support growth in 2025, even when excluding a potential boost from increased defence spending, it said on Wednesday. The Augsburg-based company, which at the end of January reported preliminary full-year revenue in line with its guidance, said its order backlog was 5 billion euros ($5.39 billion) at the end of 2024. Make sense of the latest ESG trends affecting companies and governments with the Reuters Sustainable Switch newsletter. Sign up here. It forecast revenue of 1.3 billion euros for the year, in line with analysts' mean estimate in an LSEG poll and above last year's figure of 1.1 billion euros. Like Rheinmetall ( opens new tab two weeks ago, Renk also said the outlook did not take into account any further market potential from increased defence spending in the European Union. A changed stance in Washington towards European defence and talks of historical investment in the EU have been boosting stocks in the sector, with Europe's benchmark defence and aerospace index (.SXPARO), opens new tab gaining more than 30% so far this year. "I think the mid-term guidance will be more and more framed as cautious with some upside," said Christian Reindl, a portfolio manager at Union Investment which holds shares in Renk. The company maintained its target of 2 billion euros in revenue by 2028. It also sees adjusted operating earnings of between 210 million and 235 million euros in 2025, while analysts polled by Vara were expecting 225 million euros on average. "My assumption is that they progress better on the efficiencies of their production facilities in Germany and the U.S. and there might be some upside on the operating profit throughout the year," Reindl told Reuters. Renk's shares, which were included in Germany's mid-cap equities index (.MDAXI), opens new tab earlier this month after doubling in value since January, fell 1% in early trading. ($1 = 0.9272 euros)

Des Moines bites into mosquito control program, reduces spraying and cuts testing
Des Moines bites into mosquito control program, reduces spraying and cuts testing

Yahoo

time14-03-2025

  • Health
  • Yahoo

Des Moines bites into mosquito control program, reduces spraying and cuts testing

Des Moines could be in for an itchy summer. The city is adding its mosquito abatement program to its list of proposed service cuts to help address a $17 million deficit in the upcoming fiscal year 2026 budget, which starts July 1. Mosquito abatement has historically included spray treatments, monitoring in areas with high mosquito populations and testing for diseases like West Nile virus, as well as a hotline where residents can call in to report issues. The program is under the Neighborhood Inspections Division, which oversees services such as odor control, trash and debris and rental inspections. The city spent nearly $375,000 on mosquito control in fiscal year 2025, according to Chris Reindl, an inspector supervisor. That could be slashed to about $75,000 this coming fiscal year under the proposed budget. The decision to scale back the program comes after Iowa experienced a thriving mosquito population in 2024. This included the state's capital city, where counts were high due to a wet spring and warm weather, city officials previously said. There were more than 55 types of mosquitoes found in Iowa in 2024, according to Ryan Smith, associate professor of plant pathology, entomology and microbiology at Iowa State University. That includes some disease-carrying mosquitoes, which can transmit the West Nile virus in Iowa. Some mosquitoes in Des Moines last June tested positive for West Nile virus, according to a city news release from 2024. There were at least 21 West Nile cases in humans in Iowa last year, according to the Centers for Disease Control and Prevention. More: Iowa's mosquito population is thriving in 2024. What does that mean for Iowans? The proposal calls for the city to scrap ULV adulticide spraying, mosquito trap testing, and a hotline where residents could call to report standing water or high levels of mosquitoes, Reindl said in an email. Residents used to be able to call the hotline to request to be on the 'no-spray list.' Due to budget constraints, the city's amended contract with Clarke calls for one aerial larvicide treatment — which targets mosquitoes in the larval stage to prevent them from becoming adults — sometime in late April or early May at sites where mosquito breeding can occur, according to Reindl. The treatment will include locations in east and southeast Des Moines, as well as near Sargent Park on the northeast side and along both sides of the Des Moines River on the city's northwest side, according to the city's website. The Des Moines City Council will vote on the new budget in April. Other changes and cuts include a possible increase in city parking fines and the elimination of the city's two-person sustainability office. Des Moines City Manager Scott Sanders also recommended cutting Birdland Pool, a beloved northside fixture, but it was rescinded after public pushback. The pool will likely stay open through the 2026 summer season, though not without impacts on other services. Community members can provide suggestions and feedback on the proposed budget at More: How to protect yourself from West Nile virus after Iowa sees its first case for 2024 The best way to protect yourself from mosquitoes is to prevent mosquitoes from breeding near and around you. First, eliminate standing water that can accumulate in buckets, old tires and anything that can hold water. These are places mosquitoes can lay their eggs, Smith said. Keep swimming pool water treated and circulating, and empty and change the water in bird baths, fountains, wading pools and other areas at least weekly, according to the U.S. Environmental Protection Agency. This helps to "destroy potential mosquito habitats." Make sure you have window and door screens and cover any gaps that would allow mosquitoes to enter your home. To avoid mosquito bites, the EPA recommends wearing clothing that covers exposed skin, including tucking in shirts or tucking in pants into socks to close any gaps that insects could enter. Visit to search for tips for picking the right insect repellent to protect yourself from mosquito bites. Virginia Barreda is the Des Moines city government reporter for the Register. She can be reached at vbarreda@ Follow her on X at @vbarreda2. This article originally appeared on Des Moines Register: Des Moines cuts back mosquito spraying, eliminates West Nile testing

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