Latest news with #Ropinirole
BBC News
12-03-2025
- Health
- BBC News
Ropinirole: 'Prescription medication made me a gambling addict'
"I wake up in pain, but the pain is more comforting than what I went through." Phil Stevens, from Hampshire, said he developed an addiction to gambling and spending after taking prescription medication for restless leg syndrome (RLS).The 66-year-old has said he is now reluctant to take anything for the claimed his GP did not warn him about the side effects of the drug and after taking legal action against his doctor he received a £70,000 settlement - but they did not admit liability. The BBC contacted Mr Stevens' GP but they declined to comment on the Stevens was prescribed ropinirole in is a type of dopamine agonist, which is commonly given to patients in the UK with neurological conditions like Parkinson's disease and side effects are listed in the medication leaflet and online but Mr Stevens said if he was warned directly about possible side effects he "would never have taken it". '£6.5k on fishing equipment' Speaking from the home he shares with his wife in Ringwood, Mr Stevens admitted he did occasionally bet before he took the the four years while he was taking Ropinirole he said he found himself using gambling websites in the early hours of the morning and he spent all of his and his wife's savings."We had another house that we owned, that we rented out, and that was part of our pension plan but we had to sell it to get money back in the bank again," he with the gambling, Mr Stevens also engaged in uncontrollable spending."In a short period, I spent £6,500 on fishing equipment," he said."None of it seemed wrong, that's the craziness of it, it all seemed so right at the time." Mr Stevens also has multiple sclerosis (MS) and his family did not challenge him because they believed his changing behaviour was caused by this neurological said it was not until he applied to take part in an MS drug trial that he realised something was said a consultant during the trial told him to stop taking Ropinirole "immediately".Mr Stevens said he researched the drug online and found other cases where people had struggled with addiction linked to dopamine Vaughan, a solicitor with Leigh Day, represented Mr Stevens when he took legal action against his said the first case like this which she settled was in 2015."My hope is that these cases will shine a light on the issue and patient safety will improve as a result," she Stevens said he was not aware how much he had spent until he went through his accounts with Ms Vaughan."I just cried my eyes out, I just could not believe what I had done," he receiving a financial settlement, Mr Stevens said he was still living with guilt."All I ever wanted was an apology but I'm never going to get that apology, so I'll never get rid of the guilt," he explained. Studies have found that 10-20% of patients who take a dopamine agonist, suffer from some form of impulse control disorder (ICD).Julie Gould is from RLS UK, a charity that supports people with the condition in the wants better training for doctors when it comes to RLS and is calling for dopamine agonists to only be used in end of life scenarios. 'Get all the information' Dr Michael Mulholland, vice chair of the Royal College of GPs, said: "Prescribing and de-prescribing are both included in the GP curriculum which all GP registrars (trainees) must demonstrate a competence of in order to practise independently as a GP in the UK."Restless leg syndrome will specifically be included in the updated GP curriculum, due to take effect from August 2025," he ropinirole medication Mr Stevens took is sold under the brand name Requip and was manufactured by Glaxo Smyth Kleine (GSK).A GSK spokesperson said "Extensive clinical trials and more than 17 million patient treatments worldwide since 1996 have continued to show Requip to be an effective treatment for Parkinon's disease and restless legs syndrome, with a well-characterised safety profile. "As with all medicines, Requip has potential side effects and these are clearly stated in the prescribing information. "Patients should only take Requip under the direction of a medical professional."Reflecting on his experience, Mr Stevens said: "I'm not saying don't take it, I don't have any right to say that but what I would say, if you're in a position where a doctor was to prescribe you that medication, ask the questions, get all the information and then make that informed choice." You can follow BBC Hampshire & Isle of Wight on Facebook, X (Twitter), or Instagram.
Telegraph
11-03-2025
- Health
- Telegraph
Parkinson's drug caused ‘deviant' sexual behaviour
A popular drug prescribed for Parkinson's disease caused side effects of 'deviant' sexual behaviour and gambling addiction. Patients prescribed the drug ropinirole for movement disorders, which includes Parkinson's and restless leg syndrome (RLS), have said they were not warned about serious side effects that led people to seek out high-risk behaviours. A report by pharmaceutical firm GSK revealed it learned in 2003 of the link between the drugs and 'deviant behaviour', according to the BBC. The GSK review cited two men taking the treatment for Parkinson's who were charged with sexual offences, including one for child sexual assault. A further 20 women spoke out about their side effects after they were prescribed the drugs for RLS – a condition that causes an irresistible urge to move – as part of a BBC investigation. Ropinirole, known by brand Requip, is a dopamine agonist – this class of drugs work by mimicking the behaviour of the chemical dopamine, which occurs naturally in the brain and helps regulate movement and mood. Its levels increase when we experience pleasure or rewards, but agonist drugs can over-stimulate these feelings and under-stimulate the appreciation of consequences, leading to impulsive behaviour, according to academics. While some women reported seeking out risky sexual behaviours, others said they felt compelled to gamble or shop and racked up debts of more than £150,000. Triggered unprecedented sexual urges A woman known as Claire revealed she first began taking the drug when she developed RLS during pregnancy, which led to a relentless need to move, sleeplessness and a crawling sensation under her skin. She said she was not warned by doctors about the side effects and while ropinirole helped her symptoms, she began to feel unprecedented sexual urges after a year. Claire told the BBC she began leaving her house in the early hours of the morning to cruise for sex. She would wear a see-through top and jacket, flash her chest at any man she could find, and did so regularly, in increasingly dangerous locations, despite having a partner. 'There remains an element in your head that knows what you're doing is wrong, but it affects you to the point that you don't know you're doing it,' she said. It took her years to connect the urges with the medication and they disappeared almost immediately after she stopped taking the drugs. She said she feels complete 'shame' and is 'mortified' at the danger she placed herself in. Other women reported similar sexual and gambling addictions, but say they were not warned about the drugs and did not make the connection. Prof Valerie Voon, a professor of neuropsychiatry at the University of Cambridge, said patients taking ropinirole should be specifically warned about the side effects, and screened by the NHS, because their impact can be 'devastating'. 'There's a lot of stigma and shame attached to it, and people don't realise that it's associated with medication,' she said. Impulsive behaviours, including gambling and increased sex drive, are listed side effects in medicine leaflets for dopamine agonist drugs – and are thought to affect between six per cent to 17 per cent of RLS patients taking them, according to the regulator, the National Institute of Health and Care Excellence. Jailed for 'uncontrolled exhibitionism' The GSK report from 2003 reportedly described the 'deviant behaviour' of two men who were prescribed ropinirole for Parkinson's disease. The documents revealed a 63-year-old man sexually assaulted a seven-year-old girl, leading to a custodial sentence. His libido had increased significantly from the start of his treatment with ropinirole and his 'libido problem subsequently resolved' after his dose was reduced. In the second case, a 45-year-old man carried out 'uncontrolled acts of exhibitionism and indecent behaviour'. His sex drive was reported to have increased before being prescribed ropinirole but his urges 'intensified' after the treatment. A class action was brought against GSK in 2011 by four sufferers of Parkinson's disease. This was settled and GSK denied liability. A GSK spokesman said: 'Extensive clinical trials and more than 17 million patient treatments worldwide since 1996 have continued to show Requip to be an effective treatment for Parkinson's disease and Restless Legs Syndrome, with a well-characterised safety profile. 'As with all medicines, Requip has potential side effects and these are clearly stated in the prescribing information. Patients should only take Requip under the direction of a medical professional.' A spokesman for the Medicines and Healthcare products Regulatory Agency said: 'The MHRA approved product information for ropinirole and pramipexole contains warnings about the risk of impulse control disorder which can involve impulses of a sexual nature. 'As impulses are variable and individualised, a specific reference to 'deviant' sexual behaviour is not included but as outlined in the full text of the warning, the warning highlights that the impulses experienced can include activities that may harm the patient or others. 'It is important to note that not all patients experience this type of side effect and it is important for healthcare professionals to explain the possible risk to patients.'
The Independent
11-03-2025
- Health
- The Independent
Doctors didn't warn ‘deviant sexual behaviour' was side effect of restless leg syndrome drug
Patients who were prescribed drugs for restless leg syndrome claim doctors did not warn them about significant side effects of the medication – including risky sexual behaviours and compulsive gambling. One woman recalls leaving her house in the early hours of the morning in search for sex, while another admitted she racked up debts of £80,000 after developing a gambling addiction. The drug Ropinirole – which is a type of dopamine agonist – is offered on the NHS, but health guidance body Nice warns the medication has been linked to pathological gambling, binge eating, compulsive shopping and hyper-sexuality. Restless leg syndrome (RLS) causes a 'crawling or creeping' sensation in the feet, calves and thighs, as well as an overwhelming urge to move them, according to the NHS. The drugs are designed to work on a part of the brain that controls movement, but the same part of the brain also regulates pleasure and reward. That means people can get more pleasure than usual from stimulating activities. However, twenty women have told the BBC that doctors did not warn them of this side-effect that many say ruined their lives. An internal report by drugs firm GSK, which makes the medication, reveals the manufacturer was aware of the link between impulsive behaviours in 2003. This information was shared with drug regulators, according to GSK. GSK says leaflets contained within the medicine's packaging have mentioned a risk of 'altered' sexual interest since 2007. One woman, named only as Claire, told the BBC she developed RLS while she was pregnant and after giving birth she was prescribed Ropinirole. At first, the drug worked wonders, it calmed her restless legs and helped her sleep. But after a year she started to experience strange sexual urges. She recalled leaving her house wearing a see-through top and jacket and flashing her chest at any man she could find. Claire, who had a partner, said she did this in dangerous locations. 'There remains an element in your head that knows what you're doing is wrong, but it affects you to the point that you don't know you're doing it,' she told the BBC. It took her years to connect these urges with the medication, but explained the urges stopped almost immediately after she stopped taking the drug. Now, she battles with 'shame' and the knowledge she put herself in danger. Another woman Sue, who found herself in £80,000 of debt, said she mentioned her recent gambling behaviour to the doctor when she was being prescribed a second dopamine agonist drug, but she was not warned about the possible side effect of compulsive behaviour. In the GSK report from 2003, seen by the BBC, it described 'deviant behaviour' in two men who were prescribed Ropinirole for Parkinson's disease. One was a 63-year-old-man who sexually assaulted a seven-year-old girl after developing a 'libido problem', which led to a custodial sentence. The second case was of a 45-year-old man who carried out acts of 'indecent behaviour'. His sex drive was reported to increase after taking his treatment. In 2011, a class action was brought against GSK by four sufferers of Parkinson's disease. They said Ropinirole led to broken relationships and gambling debts. They also said despite links to such behaviours revealed in medical studies in the early 2000s, GSK did not include this warning in their medical leaflets until 2007. The class action was settled but GSK denied liability. In a statement GSK told The Independent that Requip – the brand name for Ropinirole – had been prescribed for more than 17 million treatments since 1996 and that it has undergone 'extensive clinical trials'. They said Requip has been shown to be an effective treatment for Parkinson's disease and Restless Legs Syndrome, with a 'well-characterised safety profile.' A GSK spokesperson added: 'As with all medicines, Requip has potential side effects, and these are clearly stated in the prescribing information. Patients should only take Requip under the direction of a medical professional.' It added that following the 2003 research which found a link with 'deviant' sexual behaviour, results were shared with health authorities and had informed updates in prescribing information. GSK said that the current patient information leaflet for Ropinirole makes specific reference to changes in sexual interest. It also lists a strong impulse to gamble, uncontrollable shopping, binge eating and episodes of overactivity.
Yahoo
11-03-2025
- Health
- Yahoo
Doctors didn't warn women of 'risky sex' drug urges
Patients prescribed drugs for movement disorders - including restless leg syndrome (RLS) - say doctors did not warn them about serious side effects that led them to seek out risky sexual behaviour. Twenty women have told the BBC that the drugs - given to them for RLS, which causes an irresistible urge to move - ruined their lives. A report by drugs firm GSK - seen by the BBC - shows it learned in 2003 of a link between the medicines, known as dopamine agonist drugs, and what it described as "deviant" sexual behaviour, which included a sexual assault on a child. While there is no explicit reference to this side effect in patient leaflets, the UK medicines regulator told us there was a general warning about increased libido and harmful behaviour. GSK says a risk of "altered" sexual interest is also referred to in the leaflets. Some of the women who described being drawn to risky sexual behaviour told us they had no idea of what was causing it. Others said they felt compelled to gamble or shop with no history of such activities. One accumulated debts of more than £150,000. Like many women, Claire first developed RLS during her pregnancies. The relentless need to move was often accompanied by sleeplessness and a crawling sensation under her skin. The condition persisted after giving birth and she was prescribed the dopamine agonist drug Ropinirole. She says she was not warned by doctors of any side effects. It initially worked wonders for her RLS, she says, but after a year or so she began feeling unprecedented sexual urges. "The only way I could describe it is it was just deviant," she tells us - using that word without any knowledge of the GSK research which had established a link with such behaviour. Claire says she began leaving her house in the early hours of the morning to cruise for sex. Wearing a see-through top and jacket, she would flash her chest at any man she could find. She did this regularly, she says, and in increasingly dangerous locations, despite having a partner. "There remains an element in your head that knows what you're doing is wrong, but it affects you to the point that you don't know you're doing it." Claire says it took years to connect these urges with her medication - and they disappeared almost immediately when she stopped taking it. She feels complete "shame" and is "mortified" at the danger she placed herself in. Impulsive behaviours, including gambling and increased sex drive, have long been listed as side effects in medicine leaflets for dopamine agonist drugs - and are thought to affect between 6% to 17% of RLS patients taking them, according to health guidance body NICE. A "common" side effect of any medicine is considered to only affect 1% of people who take it, according to the NHS. The drugs - which are also used to treat schizophrenia - work by mimicking the behaviour of dopamine, a natural chemical in our brains which helps regulate movement. It is known as the "happy hormone" because it is activated when something is pleasurable or we feel rewarded. But agonist drugs can over-stimulate these feelings and under-stimulate the appreciation of consequences - leading to impulsive behaviour, according to academics. The cases of what the GSK report from 2003 described as "deviant behaviour" involved two men who were prescribed Ropinirole for Parkinson's disease. In one, a 63-year-old-man sexually assaulted a seven-year-old girl, leading to a custodial sentence. The documents said the perpetrator's libido had increased significantly from the start of his treatment with Ropinirole and his "libido problem subsequently resolved" after his dose was reduced. In the second case, a 45-year-old man carried out "uncontrolled acts of exhibitionism and indecent behaviour". His sex drive was reported to have increased prior to being prescribed Ropinirole but his urges "intensified" after the treatment. Prevalence rates of what GSK calls "deviant" sexual behaviours caused by the drugs are unknown and tend to be under-reported by those who experience them, according to Valerie Voon, a professor of neuropsychiatry at the University of Cambridge. "There's a lot of stigma and shame attached to it, and people don't realise that it's associated with a medication," she says. Prof Voon believes risky sexual behaviours - beyond a purely increased libido - should be specifically warned about and screened by the NHS, because their impact can be "devastating". RLS is believed to affect about one in 20 adults - and women are about twice as likely to suffer as men. The 20 sufferers we spoke to say not only had doctors failed to tell them of the potentially serious side effects of the drugs, but also failed to review the impact of the medication on their bodies subsequently. Sarah was in her 50s when she was prescribed another dopamine agonist drug made by a different manufacturer. "Previously I'd have had no interest if Brad Pitt walked in the room naked," she says. "But it turned me into this raging woman who kept taking sexual addiction further." Sarah began selling used underwear and videos of sex acts online - and organising telephone sex with strangers. She also began shopping compulsively - ending up with £30,000 of debt. To combat the effects of the dopamine agonist, she began self-medicating by taking pain-relieving opioids and sleeping pills. She ended up being admitted to rehab - but that meant her driving licence was taken away and she lost her job. "I turned to things that weren't healthy - I knew that the behaviour wasn't me, but I couldn't control it," she tells the BBC. If you have more information about this story, you can reach Noel directly and securely through encrypted messaging app Signal on: +44 7809 334720, by email at external or on SecureDrop A third woman, Sue, says she was prescribed two different dopamine agonist drugs without being warned of compulsive behaviour side effects on either occasion. She even mentioned recent gambling behaviour when the second drug was prescribed, she says. She went on to rack up debts of £80,000. "The effect on my family was horrific - it was life-changing money to lose," she says. "But at the time I didn't know it was no fault of my own." A class action was brought against GSK in 2011 by four sufferers of Parkinson's disease - the BBC has learned. They said Ropinirole led to gambling debts and broken relationships. They also complained that despite a link between such behaviours and the drug having been established in medical studies as early as 2000, GSK had failed to include any warnings in its product literature until March 2007. The class action was settled but GSK denied liability. Cases of serious side effects have also been reported in other countries, particularly in relation to the use of drugs for Parkinson's disease. In France, a court awarded damages to a father of two who complained that Ropinirole had given him compulsive homosexual urges, while another man without a criminal record began torturing cats. In the US, the American Academy of Sleep Medicine recommends the drugs should only be used for short-term treatment, such as end-of-life care. Many of the women the BBC spoke to also complained that prolonged use of the drugs also worsened their underlying RLS. It meant their dosage had been increased which, in turn, had exacerbated their compulsive behaviour - a process known as augmentation. Dr Guy Leschziner, a consultant neurologist, says the drugs still play an important role but he believes that drug companies, health authorities and doctors need to better warn patients of these side effects. "Not everybody knows the kinds of really quite dramatic changes that can occur," he says. If you would like help with any of the issues raised in this story, you can find sources of support from the BBC Action Line here In a statement, GSK told the BBC Ropinirole had been prescribed for more than 17 million treatments and undergone "extensive clinical trials". It added the drug had proven to be effective and had a "well-characterised safety profile". "As with all medicines, [it] has potential side effects and these are clearly stated in the prescribing information," it said. In response to its 2003 research that had found a link with "deviant" sexual behaviour, GSK told us this was shared with health authorities and had informed updates in prescribing information - which now lists "altered or increased sexual interest" and "behaviour of significant concern" as side effects. The current patient information leaflet for Ropinirole makes specific reference to changes in sexual interest on five occasions - almost exclusively warning about the frequency or strength of such feelings as potentially "abnormally high", "excessive" or "increase[d]". The UK's Medicines and Healthcare products Regulatory Agency (MHRA), said that while a specific reference to "deviant" sexual behaviour is not included in warnings, such impulses vary and a general warning about activities which may be harmful is included. It also said that it is important for healthcare professionals to explain the possible risk to patients and not all experience these types of side effects. The Department of Health and Social Care declined to comment. Some names have been changed in this article to protect people's identities.
BBC News
11-03-2025
- Health
- BBC News
Doctors didn't warn women of 'risky sex' drug urges
Patients prescribed drugs for movement disorders - including restless leg syndrome (RLS) - say doctors did not warn them about serious side effects that led them to seek out risky sexual women have told the BBC that the drugs - given to them for RLS, which causes an irresistible urge to move - ruined their lives.A report by drugs firm GSK - seen by the BBC - shows it learned in 2003 of a link between the medicines, known as dopamine agonist drugs, and what it described as "deviant" sexual behaviour, which included a sexual assault on a there is no explicit reference to this side effect in patient leaflets, the UK medicines regulator told us there was a general warning about increased libido and harmful behaviour. GSK says a risk of "altered" sexual interest is also referred to in the of the women who described being drawn to risky sexual behaviour told us they had no idea of what was causing it. Others said they felt compelled to gamble or shop with no history of such activities. One accumulated debts of more than £150, many women, Claire first developed RLS during her pregnancies. The relentless need to move was often accompanied by sleeplessness and a crawling sensation under her condition persisted after giving birth and she was prescribed the dopamine agonist drug Ropinirole. She says she was not warned by doctors of any side effects. It initially worked wonders for her RLS, she says, but after a year or so she began feeling unprecedented sexual urges."The only way I could describe it is it was just deviant," she tells us - using that word without any knowledge of the GSK research which had established a link with such behaviour. Claire says she began leaving her house in the early hours of the morning to cruise for sex. Wearing a see-through top and jacket, she would flash her chest at any man she could find. She did this regularly, she says, and in increasingly dangerous locations, despite having a partner."There remains an element in your head that knows what you're doing is wrong, but it affects you to the point that you don't know you're doing it."Claire says it took years to connect these urges with her medication - and they disappeared almost immediately when she stopped taking it. She feels complete "shame" and is "mortified" at the danger she placed herself behaviours, including gambling and increased sex drive, have long been listed as side effects in medicine leaflets for dopamine agonist drugs - and are thought to affect between 6% to 17% of RLS patients taking them, according to health guidance body NICE. A "common" side effect of any medicine is considered to only affect 1% of people who take it, according to the drugs - which are also used to treat schizophrenia - work by mimicking the behaviour of dopamine, a natural chemical in our brains which helps regulate movement. It is known as the "happy hormone" because it is activated when something is pleasurable or we feel agonist drugs can over-stimulate these feelings and under-stimulate the appreciation of consequences - leading to impulsive behaviour, according to academics. The cases of what the GSK report from 2003 described as "deviant behaviour" involved two men who were prescribed Ropinirole for Parkinson's disease. In one, a 63-year-old-man sexually assaulted a seven-year-old girl, leading to a custodial documents said the perpetrator's libido had increased significantly from the start of his treatment with Ropinirole and his "libido problem subsequently resolved" after his dose was the second case, a 45-year-old man carried out "uncontrolled acts of exhibitionism and indecent behaviour". His sex drive was reported to have increased prior to being prescribed Ropinirole but his urges "intensified" after the rates of what GSK calls "deviant" sexual behaviours caused by the drugs are unknown and tend to be under-reported by those who experience them, according to Valerie Voon, a professor of neuropsychiatry at the University of Cambridge."There's a lot of stigma and shame attached to it, and people don't realise that it's associated with a medication," she Voon believes risky sexual behaviours - beyond a purely increased libido - should be specifically warned about and screened by the NHS, because their impact can be "devastating".RLS is believed to affect about one in 20 adults - and women are about twice as likely to suffer as 20 sufferers we spoke to say not only had doctors failed to tell them of the potentially serious side effects of the drugs, but also failed to review the impact of the medication on their bodies was in her 50s when she was prescribed another dopamine agonist drug made by a different manufacturer."Previously I'd have had no interest if Brad Pitt walked in the room naked," she says. "But it turned me into this raging woman who kept taking sexual addiction further."Sarah began selling used underwear and videos of sex acts online - and organising telephone sex with strangers. She also began shopping compulsively - ending up with £30,000 of combat the effects of the dopamine agonist, she began self-medicating by taking pain-relieving opioids and sleeping pills. She ended up being admitted to rehab - but that meant her driving licence was taken away and she lost her job."I turned to things that weren't healthy - I knew that the behaviour wasn't me, but I couldn't control it," she tells the BBC. If you have more information about this story, you can reach Noel directly and securely through encrypted messaging app Signal on: +44 7809 334720, by email at external or on SecureDrop A third woman, Sue, says she was prescribed two different dopamine agonist drugs without being warned of compulsive behaviour side effects on either occasion. She even mentioned recent gambling behaviour when the second drug was prescribed, she says. She went on to rack up debts of £80,000."The effect on my family was horrific - it was life-changing money to lose," she says. "But at the time I didn't know it was no fault of my own."A class action was brought against GSK in 2011 by four sufferers of Parkinson's disease - the BBC has learned. They said Ropinirole led to gambling debts and broken also complained that despite a link between such behaviours and the drug having been established in medical studies as early as 2000, GSK had failed to include any warnings in its product literature until March 2007. The class action was settled but GSK denied of serious side effects have also been reported in other countries, particularly in relation to the use of drugs for Parkinson's France, a court awarded damages to a father of two who complained that Ropinirole had given him compulsive homosexual urges, while another man without a criminal record began torturing the US, the American Academy of Sleep Medicine recommends the drugs should only be used for short-term treatment, such as end-of-life care. Many of the women the BBC spoke to also complained that prolonged use of the drugs also worsened their underlying RLS. It meant their dosage had been increased which, in turn, had exacerbated their compulsive behaviour - a process known as Guy Leschziner, a consultant neurologist, says the drugs still play an important role but he believes that drug companies, health authorities and doctors need to better warn patients of these side effects."Not everybody knows the kinds of really quite dramatic changes that can occur," he says. If you would like help with any of the issues raised in this story, you can find sources of support from the BBC Action Line here In a statement, GSK told the BBC Ropinirole had been prescribed for more than 17 million treatments and undergone "extensive clinical trials". It added the drug had proven to be effective and had a "well-characterised safety profile"."As with all medicines, [it] has potential side effects and these are clearly stated in the prescribing information," it response to its 2003 research that had found a link with "deviant" sexual behaviour, GSK told us this was shared with health authorities and had informed updates in prescribing information - which now lists "altered or increased sexual interest" and "behaviour of significant concern" as side current patient information leaflet for Ropinirole makes specific reference to changes in sexual interest on five occasions - almost exclusively warning about the frequency or strength of such feelings as potentially "abnormally high", "excessive" or "increase[d]".The UK's Medicines and Healthcare products Regulatory Agency (MHRA), said that while a specific reference to "deviant" sexual behaviour is not included in warnings, such impulses vary and a general warning about activities which may be harmful is also said that it is important for healthcare professionals to explain the possible risk to patients and not all experience these types of side Department of Health and Social Care declined to names have been changed in this article to protect people's identities.
