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NDTV
8 hours ago
- Health
- NDTV
Rare Appendix Cancer On Rise Among Millennials And Gen X: Study
A rare appendix cancer is rapidly increasing among Generation X and millennials, a new study has revealed. When compared to previous generations, the incidence has tripled or quadrupled, it added. According to a paper published Monday in the Annals of Internal Medicine, appendiceal adenocarcinoma (AA) rates have tripled among Gen X and quadrupled among millennials compared to previous generations, based on an analysis of a National Cancer Institute database. The incidence of appendiceal adenocarcinoma is increasing in all age groups in the United States. Although they have not yet been studied, birth cohort patterns of AA can offer new etiologic hints on the rising prevalence. Vanderbilt University Medical Centre researchers examined data from the Surveillance, Epidemiology and End Results (SEER) program of the National Cancer Institute, which tracked incidents between 1975 and 2019. According to their data, the incidence of appendix cancer has quadrupled for those born in 1985 and tripled for those born in 1980 when compared to those born in 1945. Although appendix cancer is very rare - roughly 3,000 new cases are diagnosed each year in the US, a small portion of the more than 150,000 instances of colorectal cancer - there is a noticeable generational trend. A total of 4,858 cases of appendix cancer were reported between 1975 and 2019. The increase in appendix cancer rates, according to experts, is similar to trends in other gastrointestinal cancers, like colorectal and stomach cancers. They are also on the rise among those under 50. Increased use of ultra-processed foods, particularly processed meats and sugary beverages, as well as increased rates of obesity and metabolic syndrome, are possible causes of appendiceal adenocarcinoma (AA) among younger generations. Dr Andreana Holowatyji, the study's principal author, stressed the rise was not the result of more appendectomies because surgery rates remained constant over time. It indicates more significant lifestyle changes and environmental risk factors. "There is a disproportionate burden of appendix cancer among young individuals," Dr Andreana Holowatyji told NBC News. Early detection of appendix cancer can be difficult since its symptoms - bloating, changes in bowel habits, and appetite loss - can be ambiguous. The exact causes remain unidentified, and scientists emphasise the importance of more research into environmental exposures and molecular alterations that could contribute to appendix cancers.
India Today
9 hours ago
- Health
- India Today
Appendix cancer on the rise among US millennials, new study finds
From breast and colon to stomach and pancreatic cancers, doctors are now seeing more cases in people under the age of 50. A new study adds another surprising cancer to that list: appendix it remains extremely rare, appendix cancer is steadily increasing, especially among younger generations - millennials and Gen Z in the US, according to new research published in the Annals of Internal study, led by researchers at Vanderbilt University Medical Centre, found that the number of people diagnosed with a type of appendix cancer called appendiceal adenocarcinoma (AA) has spiked in recent decades. Using data from the National Cancer Institute's SEER program, a comprehensive US cancer registry, researchers tracked cases between 1975 and analysed trends by birth cohort and discovered a clear pattern: people born after 1945 showed rising rates of appendix cancer, with the sharpest increases among those born in 1980 and 1985. A study found that the number of people diagnosed with a type of appendix cancer has spiked in recent decades. () advertisementIn fact, rates tripled for the 1980 birth cohort and quadrupled for the 1985 group when compared to people born in 1945."This suggests that something has changed in the environment or lifestyle of newer generations that's contributing to this rise,' said lead researcher Dr. Andreana Holowatyji, assistant professor of hematology and oncology at IS THIS HAPPENING?Unlike more common cancers, the causes of appendix cancer remain appendix, a small pouch attached to the large intestine, was long overlooked and often lumped in with colon cancer. But as diagnostic tools and cancer registries improve, it's become easier to track this specific type of the number of appendectomies (surgical removal of the appendix) has stayed the same over the years, the researchers rules out the possibility that more cancers are simply being discovered because more surgeries are being researchers believe that lifestyle and environmental factors may be to blame. Rising rates of obesity and metabolic disorders among younger generations are a known risk factor for several cancers. But Holowatyji says it's probably not just one thing. The appendix, a small pouch attached to the large intestine, was long overlooked and often lumped in with colon cancer. () "It's likely a combination of influences, things like diet, chemicals in the environment, or even changes in the gut microbiome, that could be triggering changes in the body's cells and increasing the risk," she told IT MATTERS FOR INDIA'S YOUNG ADULTSThough the study was based on US data, the findings carry relevance globally, including for Indian millennials and Gen is also seeing an increase in young people diagnosed with cancers traditionally considered diseases of older inactive for long periods, high intake of processed diets, exposure to pollution, and lack of early screening all play a appendix cancer is still so rare, awareness among doctors and the public is low. This means symptoms, like unexplained bloating, changes in bowel habits, or appetite loss, can easily be dismissed as minor digestive authors of the study are calling for more research into the causes of appendix cancer, especially in younger populations, increased awareness not just among medical professionals but also among young adults themselves. advertisement
Economic Times
16 hours ago
- Health
- Economic Times
Appendix cancer rates quadruple among millennials, raising alarms for younger generations
IANS Appendix cancer rates quadruple among millennials A new study published in the Annals of Internal Medicine has revealed a sharp and troubling rise in appendix cancer rates among younger generations, particularly millennials and Generation X. Researchers at Vanderbilt University Medical Center analyzed data from the National Cancer Institute's Surveillance, Epidemiology and End Results (SEER) program, tracking cases from 1975 to 2019. Their findings show that the incidence of appendix cancer has tripled among those born in 1980 and quadrupled for individuals born in 1985, compared to people born in 1945. Although appendix cancer remains rare—about 3,000 new cases are diagnosed annually in the United States, a fraction of the more than 150,000 cases of colorectal cancer—the generational trend is significant. The study's lead author, Dr. Andreana Holowatyji, emphasized that the rise is not due to increased appendectomies, as surgical rates have remained stable over the increase points to broader shifts in environmental and lifestyle risk factors. Experts suggest that the surge in appendix cancer rates mirrors patterns seen in other gastrointestinal cancers, such as colorectal and stomach cancers, which are also rising among people under 50. Potential contributors include higher rates of obesity, metabolic syndrome, and increased consumption of ultraprocessed foods, especially processed meats and sugary beverages. However, the precise causes remain unclear, and researchers stress the need for further investigation into environmental exposures and molecular changes that may drive of appendix cancer can be vague—such as bloating, changes in bowel habits, and loss of appetite—making early diagnosis challenging. The study underscores the importance of greater awareness among both healthcare professionals and the public, as early detection remains critical for better appendix cancer incidence rising sharply in younger adults, the findings highlight an urgent need for continued research and public health vigilance to address this emerging cancer trend.
Time of India
16 hours ago
- Health
- Time of India
Appendix cancer rates quadruple among millennials, raising alarms for younger generations
Live Events (You can now subscribe to our (You can now subscribe to our Economic Times WhatsApp channel A new study published in the Annals of Internal Medicine has revealed a sharp and troubling rise in appendix cancer rates among younger generations, particularly millennials and Generation X. Researchers at Vanderbilt University Medical Center analyzed data from the National Cancer Institute 's Surveillance, Epidemiology and End Results (SEER) program, tracking cases from 1975 to 2019. Their findings show that the incidence of appendix cancer has tripled among those born in 1980 and quadrupled for individuals born in 1985, compared to people born in appendix cancer remains rare—about 3,000 new cases are diagnosed annually in the United States , a fraction of the more than 150,000 cases of colorectal cancer—the generational trend is significant. The study's lead author, Dr. Andreana Holowatyji, emphasized that the rise is not due to increased appendectomies, as surgical rates have remained stable over the increase points to broader shifts in environmental and lifestyle risk suggest that the surge in appendix cancer rates mirrors patterns seen in other gastrointestinal cancers, such as colorectal and stomach cancers, which are also rising among people under 50. Potential contributors include higher rates of obesity, metabolic syndrome, and increased consumption of ultraprocessed foods, especially processed meats and sugary beverages. However, the precise causes remain unclear, and researchers stress the need for further investigation into environmental exposures and molecular changes that may drive of appendix cancer can be vague—such as bloating, changes in bowel habits, and loss of appetite—making early diagnosis challenging. The study underscores the importance of greater awareness among both healthcare professionals and the public, as early detection remains critical for better appendix cancer incidence rising sharply in younger adults, the findings highlight an urgent need for continued research and public health vigilance to address this emerging cancer trend.
Yahoo
03-06-2025
- Business
- Yahoo
Otto Aviation Standardizes on Galorath's AI-Powered Estimation Platform to Drive Price-to-Win Strategies Across Sustainable Aerospace Initiatives
LONG BEACH, Calif., June 3, 2025 /PRNewswire/ -- Galorath, the premier AI-powered estimation platform provider for cost, schedule, and risk analysis, today announced that Otto Aviation (Otto) is standardizing on its flagship SEER® platform. Otto will leverage the platform's structured operational intelligence to anticipate costs and streamline production efforts as it works to create the future of sustainable air travel through paradigm-shifting design, performance, and economics. In the evolving supply chain landscape, Otto will rely heavily on SEER for Manufacturing (SEER-MFG™) and SEER-3D predictive data modules to develop accurate and efficient manufacturing and assembly costs. SEER allows Otto to build parametric estimates and risk profiles by leveraging historical insights, improving planning precision. The Otto team can interact directly with its proprietary and Galorath-sourced historical data. This simplifies WBS generation and unlocks actionable, data-backed insights earlier in the process. "As we enter the next phase of aircraft development, time-to-market, quality control, and resource accuracy are critical to our success," said Obi K. Ndu, PhD, Chief Information and Digital Officer, Otto Aviation. "Integrating Galorath's SEER platform into workflows ensures we have the right tools to combat economy-driven constraints and focus on cost, outcome predictions, and meeting design requirements, keeping us ahead of the curve with a strategic advantage." Guided by a team of experienced and accomplished aerospace leaders, Otto is ushering in a new era of transonic super-laminar (TSL) aircraft that is more operationally efficient and environmentally friendly. As Otto approaches design initiatives for customers, the SEER-MFG data module empowers Otto with accurate estimation, predictive analytics, risk analysis tools, labor and resource forecasting, and material and production modeling. As designs evolve, the SEER 3D data module allows Otto to update and refresh estimates by generating detailed costs from any CAD system and evaluating cost-saving alternatives. "Delivering sustainable flight innovation demands precision, flexibility, and rigorous control. Galorath's AI-powered estimation platform brings structure to that complexity," said Charles Orlando, Chief Strategy Officer at Galorath. "The complexities of navigating quality control issues, new regulations, and persistent supply chain constraints require a sophisticated solution. Galorath's AI-powered estimation platform delivers structured cost, schedule, and risk analysis through a unified environment that scales across Otto team members and designs." SEER AI-Powered Estimation and Planning Built on Galorath's trusted SEER modeling framework, the platform combines analytical depth with intuitive access. SEER's core modeling framework is refined over decades of complex program execution that addresses the needs of cost, schedule, labor, risk, should-cost, and price-to-win estimation and analysis for hardware, software, manufacturing, and information technology (IT). The platform's operational intelligence layer, SEERai™, is integrated throughout the experience. It enables natural interaction, embedded guidance, and intelligent automation – reducing cycle time, improving alignment, and unlocking knowledge trapped in documents, processes, and expert memory. For more information about the SEER platform, visit About Otto Aviation Otto is creating ultra-efficient, sustainable flight through paradigm-shifting technologies. Otto distinguishes itself as an aerospace trailblazer through its selection to participate in the OECIF-resourced, DARPA-led Energy Web Aircraft program, showcasing a strong commitment to innovation. For more information, visit About Galorath Incorporated Galorath delivers an AI-powered business operations platform grounded in decades of real-world cost, schedule, and risk validation for operations, supply chains, and manufacturing. Their flagship SEER® platform is trusted by industry giants in high-stakes environments, like Accenture, NASA, Boeing, the U.S. Department of Defense, and BAE Systems (EU), among others. Built on Galorath's trusted SEER modeling framework, the platform combines analytical depth with intuitive access to accelerate time to market, enhance project predictability and visibility, and ensure project costs are on track. For more information, visit SEER is a registered trademark of Galorath Incorporated. SEER-MFG and SEERai are trademarks of Galorath Incorporated. All other trademarks are the property of their respective owners. This press release may contain forward-looking statements that involve risks and uncertainties, including statements regarding the future financial performance, business strategies, market conditions, and product development plans of the companies mentioned. Actual results may differ materially from those expressed or implied in these forward-looking statements due to various factors, including those discussed in filings with the Securities and Exchange Commission. The companies mentioned here undertake no obligation to update any forward-looking statements contained herein, whether due to new information, future events, or otherwise. View original content to download multimedia: SOURCE Galorath Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
