Latest news with #SLEEP2025
Yahoo
a day ago
- Business
- Yahoo
PLT to Present New Sleep Ingredient Study at American Academy of Sleep Medicine Conference
Serezin™ Restorative Sleep + Pain Relief is Clinically Demonstrated to Provide Fast-Acting Nighttime and Daytime Pain Relief, Make Falling Asleep Easier and Promote Waking Up Feeling More Alert and Refreshed MORRISTOWN, N.J., June 4, 2025 /PRNewswire/ -- PLT Health Solutions, Inc. announced that it will be presenting clinical study results for its Serezin™ Restorative Sleep + Pain Relief ingredient at the American Academy of Sleep Medicine Conference being held June 7-11 in Seattle, WA USA. Dawna Salter-Farfan, PhD, RD, PLT's Senior Clinical Research Manager, will be conducting a poster session Wednesday, 6/11/2025, at 10:00 AM during the Clinical Sleep Science and Practice session will cover results of a recent clinical trial on Serezin and will present data specifically on results with women. An abstract entitled An Herbal Supplement Improves Restorative Sleep and Sleep Quality, Elevates Mood, and Increases Total Sleep Time," was published in the May edition of the journal SLEEP. ) According to Dr. Salter-Farfan, these presentations are an effort by PLT to reach a wider audience for Serezin research. "We are excited to present our high-impact research findings at SLEEP 2025. We will be showing data demonstrating Serezin improves sleep quality and quantity, but with a special emphasis on the improvements shown within the female-only cohort of our study. While many of us look to tracking devices to understand our sleep, these data often do not align with our experience. Waking up feeling rested, restored, and refreshed is the defining characteristic of a great night's sleep. By providing relief for nighttime aches and pain, Serezin unlocks the benefits of restorative sleep so that men and women can have better days, every day," she added. SLEEP 2025 is the annual meeting of the Associated Professional Sleep Societies, LLC (APSS), a joint venture of the American Academy of Sleep Medicine (AASM) and the Sleep Research Society (SRS). SLEEP is considered the world's premier clinical and scientific meeting for sleep medicine, sleep and circadian research, and sleep health. The meeting brings together leading experts, innovators, and attendees from across the United States and around the world. New Clinical Study Points to Broad Ranging Benefits A comprehensive 4-week, double-blind, placebo-controlled study was conducted on 60 healthy men and women ages 50-70 years. Subjects self-reported disturbed sleep due to everyday aches and pains. They received either a 300 mg dose of Serezin a day or a placebo. Measurements were conducted at 1, 2 and 4 weeks. Key findings Include: Improved Restorative Sleep Within 1 Week: Subjects taking Serezin woke up feeling more rested and restored within the first week. By four weeks, subjects taking Serezin experienced a 64% greater improvement in restorative sleep than those taking placebo. Reduce Every Day Aches and Pains Within 1 Week: Significant improvements in pain scores started on Day 7 for the Serezin group. By Day 28, subjects taking Serezin experienced a 2.6x greater reduction in nighttime discomfort and a 75% greater reduction in daytime discomfort compared to the placebo. Easier to Fall Asleep and Better Sleep Quality Within 2 Weeks: With statistically significant improvements by Day 14, subjects taking Serezin experienced improvements in getting to sleep that were 85% greater than those taking a placebo and 93% greater improvements in sleep quality than those taking a placebo as assessed by the Leeds Sleep Evaluation Questionnaire. Improvements in Wake-Up Experience Within 2 Weeks: Subjects taking Serezin reported having a significantly easier time waking up in the morning and feeling more alert with better motor control upon waking, as assessed by the Leeds Sleep Evaluation Questionnaire. Serezin Improved Mood Within 2 Weeks: Mood states were evaluated using a validated questionnaire covering six domains: tension, depression, anger, vigor, fatigue, and confusion. Serezin subjects reported improved overall mood starting at Day 14. For the study, subjects reported a 2.2x improvement in overall mood. According to Steve Fink, Vice President, Marketing for PLT, the company has a growing range of solutions for sleep and relaxation in its ingredient portfolio. "Cognitive health is an intense area of interest and innovation at PLT today, with a broad portfolio that addresses Cognitive Performance, Mental Energy, Stress and Mood and Sleep and Relaxation. We have active clinical programs supporting all of these consumer needs," he said. "Serezin is an exciting ingredient in the sleep space because it features a different approach to promoting restorative sleep than many of the ingredients on the market today. We feel that this study can help consumer products companies develop compelling, trustworthy messaging for a new generation of sleep support products," he said. Media Contact: Mark FalconerSciencewerks Voice: 407-412-9705E-mail: 396244@ Company Contact: Steve Fink PLT Health Solutions, Inc. Voice: 973-984-0900 x214E-mail: 396244@ View original content to download multimedia: SOURCE PLT Health Solutions Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Yahoo
2 days ago
- Health
- Yahoo
Among youths, are night owls more impulsive than morning larks?
Among adolescents, night owls appear to be more impulsive than their morning lark peers, according to a new study being presented at the SLEEP 2025 annual conference in Seattle. Those with a self-reported preference for staying up late and sleeping in — the night owls — reported 'greater negative urgency and lack of perseverance, which are two aspects of impulsivity,' according to material from the American Academy of Sleep Medicine. The release said they were more apt to act impulsively when they experienced negative emotions and they quit tasks that felt difficult. But when objective measurements of circadian phase were used, the research didn't find an association between sleep-time preference and impulsivity. 'Surprisingly, we did not find a significant link between dim light melatonin onset and impulsivity in our sample,' said lead author Riya Mirchandaney, a doctoral candidate in clinical-health psychology at the University of Pittsburgh. 'This suggests that there may be unmeasured psychological or behavioral factors influencing both impulsivity and the self-assessment of circadian preference, regardless of the timing of an individual's internal circadian clock.' The academy describes circadian rhythms as biological rhythms that all living organisms have. It's a body clock synchronized to a 24-hour light-dark cycle. 'Circadian preference reflects an individual's desired timing of sleep and wake, and circadian timing can be objectively measured by analyzing saliva or blood plasma to detect dim light melatonin onset,' the group notes. More than 200 adolescents took part in the research across two different studies. They were average age of 17 and just over 6 in 10 were female. The study relied on self-reported assessments of impulsivity and circadian preference, then lab samples of saliva were used to assess biological circadian phase by looking at dim light melatonin onset. For a week, the participants also wore a wrist device to estimate their sleep midpoint and sleep duration. Each also completed an assessment of impulsivity at bedtime. Mirchandaney said the results might one day be used to study how to help teens temper impulsivity, 'a well-established contributor to alcohol and substance use,' per the release. The researchers believe that adolescence could be a valuable developmental period for using therapeutic interventions to advance sleep and circadian timing. The National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism both contributed to funding the study. Its abstract was published in an online supplement of the journal Sleep. Other studies back up the link between adolescent sleep and impulsive behaviors. For example, in 2019, a study from Sweden published in Sleep Medicine: X reported a 'bidirectional' link between adolescent sleep problems and impulsive behaviors over time. 'Youths who experienced sleep problems also experienced increased difficulties with impulse control, and problems regulating impulses were also linked with increases in sleep problems, and these effects were systematic over two years. Moreover, age did not moderate these associations but impulsive behaviors had a larger impact on girls' insomnia as compared to boys,' per that study. Johns Hopkins University has reported that 'teens love to label themselves 'night owls,' trading stories of all-nighters and sleeping away an entire Saturday.' The article notes that adolescent and teen years are a time when a natural shift in circadian rhythm occurs, so they are frequently wide awake at 11 p.m. and then sleep-deprived because of school start times and homework and other activities. Pediatrician Dr. Michael Crocetti reported that teens need between nine and nine-and-a-half hours of sleep, which is an hour more than they needed when they were 10. The extra hour — if they actually get it — helps with growth, brain development and also protects from some serious consequences like depression and poor choices like drug use. That article ties in some suggestions to encourage more sleep among teens, including starting the day with a burst of sunshine, linking car privileges to good sleep, encouraging afternoon naps and banning texting from the bedroom, among other things. The experts at Johns Hopkins also suggest avoiding a drastic summer shift of pushing the sleep schedule too far off track because school's out. That could make it very hard to get back on track when school resumes. But it could also create other issues, like moodiness or excessive sleepiness during the day. There are other reasons to ponder youthful sleep patterns, including the fact that bad habits formed early may stick or create long-lasting challenges. And it's not just among adolescents, either. As Deseret News reported in 2022, night owls may be more apt to develop heart disease or diabetes than are the morning larks. And those who rise early 'seem to burn more fat as an energy source and are often more active than those who stay up late.' Those are findings from Rutgers University, published in the journal Experimental Physiology. The study said the two groups were similar in body composition, but the early risers were more sensitive to insulin levels in their blood and burned fat better while exercising and resting. Night owls didn't burn as much fat for energy; they used carbohydrates.
Yahoo
7 days ago
- Business
- Yahoo
Avadel Pharmaceuticals plc (AVDL) Showcases LUMRYZ Success with 14 Abstracts, 4 Oral Presentations at SLEEP 2025
Avadel Pharmaceuticals plc (NASDAQ:AVDL) announced it will present 14 new abstracts, including four oral presentations, at SLEEP 2025, highlighting significant advances for LUMRYZ, its once-at-bedtime sodium oxybate treatment for narcolepsy. Interim results from the real-world REFRESH study showed that patients switching from twice-nightly oxybate to LUMRYZ experienced clinically meaningful improvements in excessive daytime sleepiness (EDS), with many achieving normal Epworth Sleepiness Scale (ESS) scores. A scientist in a labcoat examining a vial of experimental biopharmaceuticals. Additional analyses from the pivotal Phase 3 REST-ON trial revealed that even those with the most severe baseline sleepiness saw their ESS scores normalize after 13 weeks on LUMRYZ, and the therapy did not worsen sleep apnea. Further data demonstrated a reduction in distressing hallucinations and improvement in sleep-related eating disorder (SRED) symptoms after switching to LUMRYZ. Long-term tolerability was underscored, with only 4% discontinuing due to side effects. Avadel Pharmaceuticals plc (NASDAQ:AVDL) emphasized that LUMRYZ, FDA-approved for adults and children aged 7 and older, offers a major benefit over traditional oxybate by eliminating the need for middle-of-the-night dosing, supporting better sleep continuity and patient care. With these compelling results, Avadel Pharmaceuticals plc (NASDAQ:AVDL) continues to solidify its leadership in innovative narcolepsy treatments. While we acknowledge the potential of AVDL to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than AVDL and that has 100x upside potential, check out our report about this READ NEXT: and Disclosure: None.
The Irish Sun
28-05-2025
- Health
- The Irish Sun
The 3 common sleep habits that increase your risk of dying young – as red flag raised over napping danger
YOU might think a quick kip during the day is harmless – or even healthy. After all, in parts of the 2 Kipping the wrong way might just shorten your life Credit: Getty Earlier this year, scientists from Texas, said that taking an afternoon nap can But now, new research from the US has flipped that idea on its head, suggesting that certain nap habits could actually raise your risk of dying young. This isn't the first time science has raised concerns - with many experts remaining wary of the adult nap. Previous studies have linked daytime snoozing to a higher risk of diabetes, obesity and . Read more on napping Now, the latest findings, set to be presented at the SLEEP 2025 annual meeting in June, have identified three key reasons why naps could be so dangerous. "People who slept longer during the day, had irregular daytime sleep patterns, or slept more around midday and early afternoon were at greater risk, even after accounting for health and lifestyle factors," lead author Dr Chenlu Gao, from Massachusetts General Hospital in Boston, said. This was especially the case for middle-aged and older adults. The study tracked over 86,000 adults with an average age of 63, monitoring their sleep patterns using Most read in Health They found the average daytime nap lasted about 24 minutes, but those who regularly took longer naps or had wildly varying nap lengths from day to day faced a higher risk of dying sooner. Napping most often around midday to early afternoon was linked to greater health risks. I spent three days at a sleep retreat - these are the top 7 things I learnt "This contradicts what we currently know about napping, so further research on that link could be warranted," Dr Chenlu added. Since mid-afternoon is usually the time experts recommend for napping, The participants were followed for up to 11 years, during which time 5,189 people - about 6 per cent of the group - died. The researchers adjusted for factors like age, sex, Even after accounting for these, the patterns of longer, irregular, or midday naps still stood out as an influencing risk factor. 2 Step-by-step guide on how to have a perfect nap - and why it's so good for you Experts aren't entirely sure why, but it could be that longer or irregular naps signal underlying health problems, or that they disrupt the body's natural rhythms more than previously thought. Other research has shown that poor sleep patterns can sometimes be a sign of other health issues, like heart disease, diabetes, or depression. Both the NHS and the American Academy of Sleep Medicine say keep naps short - around 10 to 30 minutes - and take them before mid-afternoon (around 3 pm). This helps boost energy without messing up your nighttime sleep or leaving you groggy. But you give up napping for good, the experts note that more research is needed to fully understand the risks, especially since the current study can only show links, not cause and effect. Three deadly napping habits to watch out for New research has found that certain daytime sleep patterns could increase your risk of dying young — especially if you're middle-aged or older. 1. Long naps Napping for longer than 30 minutes regularly was linked to higher mortality risk. Experts say short 'power naps' of 20–30 minutes are best. 2. Irregular nap schedules People whose nap durations varied wildly from day to day faced greater health risks. Keeping a consistent nap routine may help. 3. Napping around midday to early afternoon Although this is often the recommended time to nap, the study found people who napped most during these hours had an increased risk of early death.
Scottish Sun
28-05-2025
- Health
- Scottish Sun
The 3 common sleep habits that increase your risk of dying young – as red flag raised over napping danger
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) YOU might think a quick kip during the day is harmless – or even healthy. After all, in parts of the Mediterranean, daytime naps - or siestas - are seen as a good way to reboot your system during the post-lunch slump. 2 Kipping the wrong way might just shorten your life Credit: Getty Earlier this year, scientists from Texas, said that taking an afternoon nap can increase adults problem-solving brain power. But now, new research from the US has flipped that idea on its head, suggesting that certain nap habits could actually raise your risk of dying young. This isn't the first time science has raised concerns - with many experts remaining wary of the adult nap. Previous studies have linked daytime snoozing to a higher risk of diabetes, obesity and high blood pressure. Now, the latest findings, set to be presented at the SLEEP 2025 annual meeting in June, have identified three key reasons why naps could be so dangerous. "People who slept longer during the day, had irregular daytime sleep patterns, or slept more around midday and early afternoon were at greater risk, even after accounting for health and lifestyle factors," lead author Dr Chenlu Gao, from Massachusetts General Hospital in Boston, said. This was especially the case for middle-aged and older adults. The study tracked over 86,000 adults with an average age of 63, monitoring their sleep patterns using apple-watch-like wrist devices for a full week. They found the average daytime nap lasted about 24 minutes, but those who regularly took longer naps or had wildly varying nap lengths from day to day faced a higher risk of dying sooner. Napping most often around midday to early afternoon was linked to greater health risks. I spent three days at a sleep retreat - these are the top 7 things I learnt "This contradicts what we currently know about napping, so further research on that link could be warranted," Dr Chenlu added. Since mid-afternoon is usually the time experts recommend for napping, The participants were followed for up to 11 years, during which time 5,189 people - about 6 per cent of the group - died. The researchers adjusted for factors like age, sex, body weight, smoking, alcohol use, and how much people slept at night to make sure the links with napping weren't simply due to those other risks. Even after accounting for these, the patterns of longer, irregular, or midday naps still stood out as an influencing risk factor. 2 Step-by-step guide on how to have a perfect nap - and why it's so good for you Experts aren't entirely sure why, but it could be that longer or irregular naps signal underlying health problems, or that they disrupt the body's natural rhythms more than previously thought. Other research has shown that poor sleep patterns can sometimes be a sign of other health issues, like heart disease, diabetes, or depression. Both the NHS and the American Academy of Sleep Medicine say keep naps short - around 10 to 30 minutes - and take them before mid-afternoon (around 3 pm). This helps boost energy without messing up your nighttime sleep or leaving you groggy. But you give up napping for good, the experts note that more research is needed to fully understand the risks, especially since the current study can only show links, not cause and effect.
