Latest news with #ShandongUniversity
Cision Canada
23-06-2025
- Health
- Cision Canada
Cell Study by SDU and PKU Researchers Reveals Novel Mechanism to Regulate Glucose Metabolism
, June 23, 2025 /CNW/ -- On May 29, 2025, Professor Sun Jinpeng's team and Professor Yu Xiao's team at Shandong University, collaborating with Professor Jiang Changtao from Peking University, Professor Pang Yanli, and Professor Ji Linong, published a research paper entitled "A microbial amino-acid-conjugated bile acid, tryptophan-cholic acid, improves glucose homeostasis via the orphan receptor MRGPRE" in Cell. The study revealed the physiological and pathophysiological functions of a novel microbial-derived amino acid-conjugated bile acid, tryptophan-cholic acid (Trp-CA). It identified the membrane receptor for Trp-CA as MRGPRE. It elucidated the novel mechanism by which Trp-CA activates MRGPRE, promoting GLP-1 secretion through dual pathways: Gs-cAMP signaling and β-arrestin-1-mediated ALDOA phosphorylation, thereby improving glucose metabolism. This work provides a new paradigm for understanding the functions and molecular mechanisms of novel microbial bile acids. It offers new targets and strategies for the development of therapies against metabolic diseases. This research is the first to reveal that the microbial-derived bile acid Trp-CA improves glucose homeostasis by activating MRGPRE. It provides a new potential drug target and therapeutic strategy for Type 2 Diabetes (T2D) treatment. Furthermore, the identification of the microbial origin of Trp-CA offers a new microbial therapeutic strategy for diabetes intervention.
South China Morning Post
18-06-2025
- Science
- South China Morning Post
China's heat shield breakthrough, scientist behind J-20 radar leap: 7 science highlights
We have put together stories from our coverage on science from the past two weeks to help you stay informed. If you would like to see more of our reporting, please consider subscribing China's J-20 stealth fighter has tripled its radar detection range, thanks to semiconductor advancements over the past two decades led by Shandong University scientist Xu Xiangang, according to the university. Researchers have used a rare mineral produced mostly in China to create an artificial retina that not only restored sight in blind animals, but also gave them 'super vision' – the extraordinary ability to see infrared light. The breakthrough overcomes fundamental barriers in traditional computing by merging binary and probability-based logic while sidestepping US chip restrictions. Photo: Shutterstock China has initiated the world's first large-scale application of non-binary AI chips, integrating its proprietary hybrid computing technology into critical sectors including aviation and industrial systems.
South China Morning Post
11-06-2025
- Science
- South China Morning Post
China's J-20 stealth fighter's radar leap credited to semiconductors expert Xu Xiangang
China's J-20 stealth fighter has tripled its radar detection range, thanks to semiconductor advancements over the past two decades led by Shandong University scientist Xu Xiangang, according to the university. A silicon-carbide (SiC) semiconductor material developed by Xu's team had powered a threefold increase in the detection range of phased array radar systems, allowing Chinese radars to swiftly detect enemies and gain the first-mover advantage, the university said on its social media page. 'From the J-20's on-board systems to advanced weaponry, this 'Chinese chip' is crucial for national security,' the May 30 post said. 'It enhances the range of Chinese radars, improves missile accuracy and boosts the power of laser weapons, making it an indispensable 'hardcore shield' in defence technology.' The J-20, also known as the Mighty Dragon, is a twin-engine stealth fighter viewed as China's answer to America's F-22 'Raptor'. It officially entered active service in March 2017. Xu, who is dean of the university's Institute of Novel Semiconductors, said it was important for researchers to address the country's needs.
South China Morning Post
23-02-2025
- Politics
- South China Morning Post
Political theorist Daniel A. Bell reflects on China's melding of Confucius and Marx
Daniel A. Bell, a Canadian political theorist specialising in Confucianism and China's political meritocracy, is chair of political theory at the University of Hong Kong's law faculty. He was the first foreigner to be appointed as dean of Shandong University's school of political science and public administration, and also taught at Beijing's Tsinghua University. Advertisement In this interview, Bell shares his views on the links between the ruling Communist Party's guiding philosophy and Confucianism, as well as the fight against corruption and his outlook for the future of Chinese politics. This interview first appeared in SCMP Plus . For other interviews in the Open Questions series, click here You have previously said that the Communist Party has moved closer to the Confucian tradition in recent decades. How would you describe this change? Most intellectuals, political reformers and revolutionaries in the 20th century opposed China's traditions – with Confucianism at their core – because they blamed them for the country's backwardness and poverty, relative to the Western powers and even Japan. This culminated in a Cultural Revolution that was explicitly anti-Confucian. There was a saying that Confucius was to blame for feudal thought and we had to attack the 'four olds', meaning the backward parts of China's traditions, and replace them with a new and revolutionary thought. Advertisement But since the early 1990s, there has been a huge revival of the Confucian tradition, not just for political reasons but also because of economic reasons – not just China, but other countries with a Confucian heritage like South Korea and Japan have modernised in a relatively peaceful and harmonious way. And it turned out that some of these Confucian values that had been blamed for China's backwardness were actually helpful for modernisation – for example, this worldly outlook, this strong commitment to self-improvement, to educating future generations, and so on.
