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Globe and Mail
29-05-2025
- Business
- Globe and Mail
Central Nervous System Tumors Pipeline Appears Robust With 13+ Key Pharma Companies Actively Working in the Therapeutics Segment
DelveInsight's ' Central Nervous System Tumors Pipeline Insight 2025 ' report provides comprehensive insights about 13+ companies and 13+ pipeline drugs in Central Nervous System Tumors pipeline landscape. It covers the Central Nervous System Tumors pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. Discover the latest drugs and treatment options in the Central Nervous System Tumors Pipeline. Dive into DelveInsight's comprehensive report today! @ Central Nervous System Tumors Pipeline Outlook Key Takeaways from the Central Nervous System Tumors Pipeline Report In May 2025, Genmab announced a study will be conducted in two parts: Part 1 (dose-finding) and Part 2 (randomization). The main purpose is to assess the safety and clinical activity of GEN1042 in combination with radiotherapy or GEN1042 in combination with radiotherapy and pembrolizumab as a treatment option for participants with metastatic solid tumors. In May 2025, Stemline Therapeutics Inc. announced a study that includes a phase 1b evaluation of elacestrant in combination with abemaciclib in women and men with brain metastases from estrogen receptor (ER)-positive, human epidermal growth factor receptor-2 (HER-2) negative breast cancer. Phase 1b was designed to select the recommended phase 2 dose and is followed by an ongoing phase 2 evaluation of elacestrant in combination with abemaciclib in patients with active brain metastases from ER-positive, HER-2 negative breast cancer. In May 2025, Hoffmann-La Roche organized a study will evaluate the safety, pharmacokinetics, and efficacy of alectinib in children and adolescents with ALK fusion-positive solid or CNS tumors for whom prior treatment has proven to be ineffective or for whom there is no satisfactory standard treatment available. DelveInsight's Central Nervous System Tumors Pipeline report depicts a robust space with 13+ active players working to develop 13+ pipeline therapies for Central Nervous System Tumors treatment. Promising Central Nervous System Tumors Companies such as Shandong New Time Pharmaceutical, PIQUR Therapeutics, Ono Pharmaceutical, Janssen, LP, Kazia Therapeutics, Beijing InnoCare Pharma Tech, Celltrion, Bristol Myers Squibb, AstraZeneca, Novartis, Prelude Therapeutics, Kite, A Gilead Company, Celgene and others. The leading Central Nervous System Tumors Pipeline Therapies such as Tozuleristide, Bevacizumab, Temozolomide, Pomalidomide, Niraparib, GNC-038, Pamiparib, Thalidomide and others. Stay ahead with the most recent pipeline outlook for Central Nervous System Tumors. Get insights into clinical trials, emerging therapies, and leading companies with DelveInsight @ Central Nervous System Tumors Treatment Drugs Central Nervous System Tumors Emerging Drugs Profile F520: Shandong New Time Pharmaceutical F 520 is a humanized monoclonal antibody targeting programmed cell death 1 receptor antagonists being developed by Shandong New Time Pharmaceutical. The drug is being investigated in Phase II stage of development for the treatment of patients with Primary and secondary Central Nervous System Lymphoma. Tirabrutinib: Ono Pharmaceuticals Velexbru, discovered and developed by ONO, is a highly selective, oral BTK inhibitor and has been developed for the treatment in patients with B-cell tumors and autoimmune diseases in Japan. B-cell receptor (BCR) signaling plays a core role in the survival, activation, proliferation, maturation and differentiation of B-cell lymphocyte. In Japan, Velexbru was approved in March 2020 and launched in May 2020 for the treatment of relapsed or refractory primary central nervous system lymphoma (PCNSL). Ono Pharmaceutical has initiated a Phase II clinical trial in US with Velexbru in patients with primary central nervous system lymphoma. The Central Nervous System Tumors Pipeline Report Provides Insights into The report provides detailed insights about companies that are developing therapies for the treatment of Central Nervous System Tumors with aggregate therapies developed by each company for the same. It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Central Nervous System Tumors Treatment. Central Nervous System Tumors Companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects. Central Nervous System Tumors Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Central Nervous System Tumors market Explore groundbreaking therapies and clinical trials in the Central Nervous System Tumors Marketed and Pipeline Drugs. Access DelveInsight's detailed report now! @ New Central Nervous System Tumors Drugs Central Nervous System Tumors Companies Shandong New Time Pharmaceutical, PIQUR Therapeutics, Ono Pharmaceutical, Janssen, LP, Kazia Therapeutics, Beijing InnoCare Pharma Tech, Celltrion, Bristol Myers Squibb, AstraZeneca, Novartis, Prelude Therapeutics, Kite, A Gilead Company, Celgene and others. Central Nervous System Lymphoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as Oral Parenteral Intravenous Subcutaneous Topical Molecule Type Central Nervous System Tumors Products have been categorized under various Molecule types such as Monoclonal Antibody Peptides Polymer Small molecule Gene therapy Product Type Unveil the future of Central Nervous System Tumors Treatment. Learn about new drugs, pipeline developments, and key companies with DelveInsight's expert analysis @ Central Nervous System Tumors Market Drivers and Barriers Scope of the Central Nervous System Tumors Pipeline Report Coverage- Global Central Nervous System Tumors Companies- Shandong New Time Pharmaceutical, PIQUR Therapeutics, Ono Pharmaceutical, Janssen, LP, Kazia Therapeutics, Beijing InnoCare Pharma Tech, Celltrion, Bristol Myers Squibb, AstraZeneca, Novartis, Prelude Therapeutics, Kite, A Gilead Company, Celgene and others. Central Nervous System Tumors Pipeline Therapies- Tozuleristide, Bevacizumab, Temozolomide, Pomalidomide, Niraparib, GNC-038, Pamiparib, Thalidomide and others. Central Nervous System Tumors Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination Central Nervous System Tumors Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III Get the latest on Central Nervous System Tumors Therapies and clinical trials. Download DelveInsight's in-depth pipeline report today! @ Central Nervous System Tumors Companies, Key Products and Unmet Needs Table of Contents Introduction Executive Summary Central Nervous System Lymphoma: Overview Pipeline Therapeutics Therapeutic Assessment Late Stage Products (Phase III) Drug Name: Company Name Drug profiles in the detailed report….. Mid Stage Products (Phase II) F520: Shandong New Time Pharmaceutical Drug profiles in the detailed report….. Early stage products (Phase I) PRT811: Prelude Therapeutics Drug profiles in the detailed report….. Inactive Products Central Nervous System Lymphoma Key Companies Central Nervous System Lymphoma Key Products Central Nervous System Lymphoma- Unmet Needs Central Nervous System Lymphoma- Market Drivers and Barriers Central Nervous System Lymphoma- Future Perspectives and Conclusion Central Nervous System Lymphoma Analyst Views Central Nervous System Lymphoma Key Companies Appendix About Us DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Yash Bhardwaj Email: Send Email Phone: 09650213330 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: NV Country: United States Website:
Globe and Mail
15-04-2025
- Health
- Globe and Mail
BPDCN Market Set for Robust Growth Through 2032 Driven by Targeted Therapies and Rising Disease Awareness
The key BPDCN companies in the market include - AbbVie, ImmunoGen, Mustang Bio, Genentech, Stemline Therapeutics, Jazz Pharmaceuticals, Menarini Group, Cellex Patient Treatment GmbH, and Xencor, are actively engaged in the BPDCN market. The Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) market across the 7MM is poised for significant growth through 2032. This growth is driven by advancements in targeted therapies, increased awareness of the disease among healthcare professionals, and ongoing research and development efforts. Major pharmaceutical and biotech companies, including AbbVie, ImmunoGen, Mustang Bio, Genentech, Stemline Therapeutics, Jazz Pharmaceuticals, Menarini Group, Cellex Patient Treatment GmbH, and Xencor, are actively engaged in the BPDCN market. A recent report titled, ' Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) - Market Insight, Epidemiology And Market Forecast - 2032 ' by DelveInsight, provides a comprehensive analysis of BPDCN epidemiology, treatment landscape, and market trends across the 7MM, which includes the United States, EU4 (Germany, France, Italy, Spain), the United Kingdom, and Japan. The US leads the market with the largest annual patient population diagnosed with BPDCN, primarily due to increased awareness campaigns and improved diagnostic tools that enhance early detection rates. BPDCN is a rare and aggressive hematologic cancer that originates from plasmacytoid dendritic cells. It accounts for less than 1% of all hematologic malignancies and is characterized by rapid progression and a poor prognosis. The disease primarily affects older adults, with a median age of diagnosis around 66 years. Additionally, BPDCN has a higher prevalence among males, and individuals of Caucasian descent are slightly more affected than those from other demographics. Historically, BPDCN treatment relied on chemotherapy regimens adapted from leukemia or lymphoma protocols. However, recent breakthroughs have transformed the treatment paradigm. ELZONRIS (Stemline Therapeutics/Menarini Group), a targeted cytotoxin, was approved by the FDA in December 2018 as the first and only targeted therapy for BPDCN. Although treatment options for BPDCN are currently limited, several promising experimental therapies are under investigation. Several anti-CD123 CAR-T therapies are emerging as potential breakthroughs, utilizing genetically engineered T cells to target CD123, owing to the success of ELZONRIS. Dive deeper into the evolving BPDCN treatment landscape and uncover key innovations from targeted cytotoxins to next-gen CD123 CAR-T therapies transforming patient outcomes Combination therapies are also gaining traction, such as CD123-targeted agents combined with hypomethylating drugs like azacitidine and BCL-2 inhibitors like venetoclax, which have shown the potential to enhance antitumor responses. Furthermore, advancements in allogeneic hematopoietic stem cell transplantation (allo-HCT) are refining patient selection criteria and conditioning regimens to improve outcomes for patients who achieve remission. In March 2025, Menarini Group Announces Collaboration with VisualDx to Aid in Identifying People Who May Have BPDCN. Stay ahead with the latest breakthroughs, FDA approvals, and eco-friendly innovations shaping the future of the BPDCN treatment landscape. Visit BPDCN Recent Developments Looking ahead, the BPDCN market in the 7MM is projected to experience significant growth over the next decade as stakeholders address unmet needs through innovation and collaboration. With ongoing advancements in targeted therapies and increasing awareness among clinicians and patients alike, the market landscape for this rare malignancy is expected to expand. Table of Contents 1. Key Insights 2. Executive Summary of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) 3. Competitive Intelligence Analysis for Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) 4. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Market Overview at a Glance 5. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Disease Background and Overview 6. Patient Journey 7. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Epidemiology and Patient Population 8. Treatment Algorithm, Current Treatment, and Medical Practices 9. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Unmet Needs 10. Key Endpoints of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Treatment 11. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Marketed Products 12. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Emerging Therapies 13. Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): Seven Major Market Analysis 14. Attribute analysis 15. 7MM: Market Outlook 16. Access and Reimbursement Overview of Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) 17. KOL Views 18. BPDCN Market Drivers 19. BPDCN Market Barriers 20. Appendix 21. DelveInsight Capabilities 22. Disclaimer 23. About DelveInsight Related Reports Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Malignancy Pipeline Insight Blastic Plasmacytoid Dendritic Cell Neoplasm Pipeline Insight provides comprehensive insights about the BPDCN pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the BPDCN manufacturers, including Genentech/AbbVie, Sanofi (NASDAQ: SAN), and ImmunoGen (NASDAQ: IMGN), among others. About DelveInsight DelveInsight is a leading market research and consulting firm specializing in disease-specific insights and therapeutic market analysis. Their reports integrate real-world data, clinical trial findings, and expert interviews to deliver comprehensive industry intelligence. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Arpit Anand Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: NV Country: United States Website:
