Latest news with #THALASSA
The Hindu
a day ago
- Sport
- The Hindu
Social Butterfly and Money Bags should fight out the finish of the F.D. Wadia Trophy
Social Butterfly and Money Bags should fight out the finish of the F.D. Wadia Trophy, the feature event of Saturday's (Aug. 16) races. Rails will be announced one hour before the first race. 1. GOLDEN GUEST PLATE (1,000m), Cl. V, 4-y-o and over, rated 1 to 26 — 2.00 p.m.: 1. Mirae (1) Sandesh 60.5, 2. New Yorker (2) C. Umesh 60, 3. Youre Gorgeous (6) V.R. Jagadeesh 60, 4. Moment Of Madness (5) Ramswarup 57, 5. We Still Believe (4) Aditya 52, 6. Samson (3) A. Prakash 51.5 and 7. High Spirit (7) Avinash 50. 1. MIRAE, 2. MOMENT OF MADNESS, 3. WE STILL BELIEVE 2. MYSORE RACE CLUB TROPHY (2,000m), Cl. I, rated 80 and upward — 2.30: 1. Ruling Dynasty (3) Ramswarup 63, 2. Golden Kingdom (1) Antony Raj 61, 3. Thalassa (4) Sandesh 52.5, 4. Regal Command (5) Parmar 50.5 and 5. Coeur De Lion (2) A. Prakash 50. 1. THALASSA 3. JANARDHAN SALVER (1,400m), Cl. IV, rated 20 to 46 — 3.00: 1. Finch (3) Bhawani 61.5, 2. Liam (1) Trevor 61.5, 3. Believe (6) Mukesh K 58, 4. Empower (10) T.S. Jodha 57, 5. You (9) Aditya 55, 6. Come September (2) C. Umesh 54.5, 7. Howlin Wolf (4) Parmar 54, 8. Windborne (7) Ramswarup 54, 9. Key Largo (5) P. Dhebe 53.5 and 10. Ar First Star (8) V.R. Jagadeesh 52. 1. LIAM, 2. FINCH, 3. BELIEVE 4. SU CHALIYO PLATE (1,200m), Cl. IV Maiden, 3-y-o only, rated 20 to 46 — 3.30: 1. Miracle Of Hanukah (8) A. Gaikwad 59, 2. Timeless Fortune (2) Yash Narredu 57.5, 3. Bezalel (6) Sandesh 56.5, 4. Trail Blazer (4) N. Bhosale 56, 5. El Moran (5) C. Umesh 55, 6. Mulan (7) Trevor 55, 7. Victorious Omen (1) Mukesh K 54.5 and 8. Ministry Of Time (3) T.S. Jodha 53. 1. TIMELESS FORTUNE, 2. MULAN, 3. EL MORAN 5. F.D. WADIA TROPHY (Gr. 3) (1,400m) (Terms), 3-y-o only — 4.00: 1. Matisse (1) Trevor 57, 2. Money Bags (3) Antony Raj 57, 3. Bishop (7) A. Prakash 56.5, 4. Social Butterfly (5) Sandesh 56.5, 5. Fourth Wing (2) Yash Narredu 55.5, 6. Encino (6) Akshay K 55, 7. Johnny Mac (8) Neeraj 55 and 8. Darcy (4) Vivek G 53.5. 1. SOCIAL BUTTERFLY, 2. MONEY BAGS, 3. ENCINO 6. MAGANSINGH P. JODHA TROPHY (1,400m), (Terms) Maiden, 3-y-o only — 4.30: 1. Crimson Pirate (5) Kirtish 56, 2. Ember Tower (8) V.R. Jagadeesh 56, 3. Enforcer (1) Yash Narredu 56, 4. Jackson (10) Sandesh 56, 5. Tyrannus (9) Trevor 56, 6. Fay (7) T.S. Jodha 54.5, 7. Key West (4) P. Dhebe 54.5, 8. Merlet (3) Mukesh K 54.5, 9. Ourense (2) Bhawani 54.5, 10. Saseka (11) Neeraj 54.5 and 11. Seina (6) C. Umesh 54.5. 1. MERLET, 2. ENFORCER, 3. JACKSON 7. WAVES OF GLORY PLATE (1,200m), Cl. V, 5-y-o and over, rated 1 to 26 — 5.00: 1. Alpha Gene (1) Mosin 60, 2. Red Merlot (7) A. Prakash 60, 3. Northern Singer (2) Avinash 59.5, 4. Ariyana Star (4) Trevor 59, 5. Lion King (3) Aditya 58, 6. Falsetto (6) T.S. Jodha 57. 7. Hilma Klint (8) Abhishek Mhatre 56.5 and 8. Lightning Blaze (5) C. Umesh 51. 1. ARIYANA STAR, 2. NORTHERN SINGER, 3. RED MERLOT Day's Best: THALASSA Jackpot: 3, 4, 5, 6 & 7. Treble: 4, 5 & 6. Tanala: All races. Super Jackpot: 2, 3, 4, 5, 6 & 7.
Web Release
04-07-2025
- Health
- Web Release
A Landmark Global Trial Led from Lebanon: Mitapivat in NTDT Published in The Lancet
In a major advancement for global thalassemia care, the results of a landmark global phase 3 clinical trial of mitapivat in non-transfusion-dependent thalassemia (NTDT) led by the American University of Beirut (AUB) and the Chronic Care Center, the thalassemia center in Lebanon, have been published in The Lancet, one of the world's leading medical journals. The study, titled 'Phase 3 trial of mitapivat in non-transfusion-dependent alpha- or beta-thalassemia,' led by Dr. Ali Taher, professor of medicine at the Division of Hematology and Oncology, director of the Naef K. Basile Cancer Institute, and consultant at the Chronic Care Center served as both global principal investigator and first and corresponding author. It is the first to demonstrate the efficacy of an oral, disease-modifying therapy for both beta and alpha forms of NTDT, positioning mitapivat as a potential game changer in the treatment of this lifelong blood disorder. 'This publication is more than a scientific milestone,' said Dr. Taher. 'It's proof that Lebanon, even in its hardest times, can lead groundbreaking medical advances that change global standards of care. I'm proud this trial was conceived, led, and delivered from AUB and the Chronic Care Center.' NTDT is a lifelong inherited blood disorder that results in chronic anemia. Patients with NTDT do not require blood transfusions, but still suffer from chronic anemia and associated complications, including iron overload and reduced quality of life. Until now, therapeutic options for these patients have been limited. Mitapivat is currently under review by the United States Food and Drug Administration (FDA) for potential marketing authorization. If approved, it would become the first FDA-authorized oral disease-modifying treatment for NTDT, offering a transformative option for thousands of patients worldwide. The phase 3 trial met all of its primary and secondary endpoints, demonstrating statistically and clinically significant improvements in hemoglobin levels, alongside favorable safety and tolerability profiles. This work represents the culmination of over a decade of research, beginning with redefining the disease and understanding the morbidity and mortality risks of untreated anemia and iron overload. It builds on prior global efforts led from AUB that resulted in the approval of key therapies, including iron chelation through the THALASSA trial and luspatercept through the BEYOND trial. Both studies were led by Dr. Ali Taher, whose vision and leadership have been instrumental in transforming the global approach to thalassemia care. Widely recognized as one of the foremost experts in the field, Dr. Taher has played a central role in advancing treatment standards and improving outcomes for patients worldwide. His long-standing commitment to thalassemia research has not only shaped the current therapeutic landscape, but has also positioned Lebanon and AUB at the forefront of international medical innovation. This achievement serves as a powerful affirmation of AUB's role as a beacon of academic and clinical excellence, firmly committed to advancing health through research, education, and patient-centered innovation. It also reflects the resilience and determination of Lebanon's medical and scientific communities to contribute meaningfully to global health, despite the formidable challenges faced at home.
