Latest news with #TRT
New York Post
2 hours ago
- Health
- New York Post
Baby girl grows ‘micropenis' after laying on her dad's chest
A baby girl in Sweden reportedly sprouted a 'micropenis' after lying on her father's bare chest — turning a tender bonding moment into a bizarre biological blunder. And she's not the only one. A Swedish doctor is sounding the alarm, warning she's seen at least half a dozen similar cases in children. Here's what you need to know to make sure your child isn't next. 4 Skin-to-skin contact can help regulate the baby's body temperature, heart rate and breathing. barneyboogles – Often referred to as 'kangaroo care,' skin-to-skin contact is a common practice used to strengthen the bond between newborns and parents while supporting healthy early development. But in this case, that sweet ritual took a strange turn. After her birth, the Swedish baby girl was repeatedly placed on her father's bare chest — the same area where he had applied testosterone gel. The topical medication is commonly prescribed to men with hypogonadism, a condition in which the body doesn't produce enough sex hormones. It's more common than you might think. Research suggests that, after the age of 40, men's testosterone levels fall by about 1% each year, a biological process sometimes colloquially called 'manopause.' While hypogonadism can affect men of any age, studies suggest that roughly 40% of those over 45 and half of men in their 80s have clinically low testosterone. 4 Testosterone gel increases levels of the testosterone hormone in your body. mbruxelle – Over time, this drop can lead to a range of symptoms, including low sex drive, erectile dysfunction, fatigue, mood swings and muscle loss — issues that testosterone replacement therapy (TRT) can help treat. Unaware of the risk, the father's skin-to-skin contact inadvertently exposed his daughter to high levels of testosterone — triggering dramatic changes in her genitalia. Her parents noticed that her clitoris had begun to elongate, resembling a small penis, while her labia began to fuse, eventually looking similar to a male scrotum. Panicked, they brought their 10-month-old daughter to a doctor. Blood tests quickly identified the source. 4 Secondary exposure to testosterone gel in children can trigger adverse effects such as premature puberty. – 'I don't think people always understand how potent these treatments are,' Professor Jovanna Dahlgren, a pediatric endocrinologist at Sahlgrenska University Hospital, told local news outlet Göteborgs-Posten. 'The parents become completely desperate when they understand what has happened,' she added. The case, which occurred eight years ago, is one of at least six similar incidents Dahlgren has seen, all involving young children unintentionally exposed to hormone medication through close contact with a parent. In one case, she said, a 10-year-old boy developed breasts after coming into contact with estrogen cream his mother had been using. Fortunately, in the Swedish girl's case, her genitals began to shrink once her father stopped using the gel and the accidental exposure ceased. And while local media described the case as a 'micropenis,' experts note that's not technically accurate, as the term refers specifically to underdeveloped male genitalia — not virilized female anatomy. 4 Testosterone decline in men, common with age, can lead to side effects like erectile dysfunction. Kaspars Grinvalds – The story comes amid a surge in TRT popularity, including in the US, where prescriptions jumped from 7.3 million in 2019 to over 11 million last year, according to CBS News. High-profile names like Josh Duhamel, Sylvester Stallone, Joe Rogan — and even Health and Human Services Secretary Robert F. Kennedy Jr. — have gotten in on the hormone hack. But it's not just aging men fueling the trend. On TikTok, the hashtag 'TRT Before and After' has exploded with millions of views, showcasing ripped guys in their 20s and 30s boasting about about boosted energy levels and sex drives. Experts, however, warn TRT isn't without risks. Side effects can include acne, fluid retention, testicular shrinkage, reduced fertility and worsened sleep apnea, according to the Cleveland Clinic. TRT comes in several forms: pills, injections, patches, and gels. If you use the topical gel, the Mayo Clinic advises washing your hands thoroughly after application and rinsing the treated area before any skin-to-skin contact to avoid accidentally exposing others.
Yahoo
3 hours ago
- Business
- Yahoo
MTTI Announces Dr. Danielle Meyrick to Lead Medical Team
WEST CHESTER, Pa., July 22, 2025--(BUSINESS WIRE)--Molecular Targeting Technologies, Inc. (MTTI) today announced the appointment of Danielle Meyrick, PhD, MD, as Chief Medical Officer. Dr. Meyrick brings more than 20 years of medical research, targeted radiotherapeutic (TRT) development and leadership to MTTI. She has held Chief Medical Officer roles across radiopharmaceutical organizations including Telix Pharmaceuticals and ITM Radiopharm. Dr. Meyrick will lead MTTI's medical team to advance clinical development of lead assets, EVA101 and EVA 102 and further progress the company's radiopharmaceutical pipeline. "My career goal in the TRT area has always been to improve care and outcomes for cancer patients. I believe MTTI is an exciting company with technology that is able to deliver on this goal. Our unique EvaThera platform has demonstrated the ability to enhance delivery of radiation to tumors, minimize off-target activity and reduce dosing requirements —collectively offering a potentially safer, more effective approach to TRT. I am thrilled to be supporting the team in leading EVA101 and EVA102 through the critical final stages of development," said Danielle Meyrick, CMO of MTTI. Dr. Chris Pak, President & CEO commented "MTTI is delighted to welcome Dr. Danielle Meyrick, an experienced clinician and executive. Her perspective and track record in TRT development are key complements to our team as we expedite advancement of our targeted radiotherapeutic pipeline." Molecular Targeting Technologies, Inc. (MTTI). MTTI is a private, clinical stage biotech developing targeted radiotherapeutics (TRT). MTTI is committed to building value by translating innovative TRT to improve human healthcare. For more information: View source version on Contacts Chris Pak, Email: cpak@ Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data
Business Wire
3 hours ago
- Business
- Business Wire
MTTI Announces Dr. Danielle Meyrick to Lead Medical Team
WEST CHESTER, Pa.--(BUSINESS WIRE)--Molecular Targeting Technologies, Inc. (MTTI) today announced the appointment of Danielle Meyrick, PhD, MD, as Chief Medical Officer. Dr. Meyrick brings more than 20 years of medical research, targeted radiotherapeutic (TRT) development and leadership to MTTI. She has held Chief Medical Officer roles across radiopharmaceutical organizations including Telix Pharmaceuticals and ITM Radiopharm. Dr. Meyrick will lead MTTI's medical team to advance clinical development of lead assets, EVA101 and EVA 102 and further progress the company's radiopharmaceutical pipeline. 'My career goal in the TRT area has always been to improve care and outcomes for cancer patients. I believe MTTI is an exciting company with technology that is able to deliver on this goal. Our unique EvaThera platform has demonstrated the ability to enhance delivery of radiation to tumors, minimize off-target activity and reduce dosing requirements —collectively offering a potentially safer, more effective approach to TRT. I am thrilled to be supporting the team in leading EVA101 and EVA102 through the critical final stages of development,' said Danielle Meyrick, CMO of MTTI. Dr. Chris Pak, President & CEO commented 'MTTI is delighted to welcome Dr. Danielle Meyrick, an experienced clinician and executive. Her perspective and track record in TRT development are key complements to our team as we expedite advancement of our targeted radiotherapeutic pipeline.' Molecular Targeting Technologies, Inc. (MTTI). MTTI is a private, clinical stage biotech developing targeted radiotherapeutics (TRT). MTTI is committed to building value by translating innovative TRT to improve human healthcare. For more information:
New York Post
3 days ago
- Health
- New York Post
How to get a testosterone prescription online
New York Post may receive revenue from affiliate and advertising partnerships for sharing this content and/or when you make a purchase. Suffering from sore joints, scrambled thoughts, lagging libido, a receding hairline — or perhaps, all of the above? According to a growing community of endocrinologists, such unwelcome signs may not simply mean that you're starting to 'slow down'. These symptoms could also be due to lowered testosterone levels. A 2023 study in the Journal of Clinical Endocrinology revealed that testosterone levels in American men have plummeted about 1% per year since the 1980s. There are several potential causes that have been explored, including lifestyle, diet, and environmental factors. However, the decline in testosterone can not be attributed to aging alone. Business leaders, like Deep Patel, are working to raise more awareness around what he has described as the 'male version of menopause,' and bring men a safe, accessible solution — Testosterone Replacement Therapy (TRT). Find Out About Our Top TRT Pick 7 Ulo Ulo Feeling low on energy? Ulo offers a personalized approach to testosterone replacement therapy (TRT), starting with an at-home lab test and virtual consultation with a licensed provider. If TRT is recommended, treatment options — including injections, gels, and oral medications — are delivered straight to your door. Plans start at $159/month. You'll only be charged if a provider determines treatment is appropriate and writes a prescription. Treatment is currently available in select states and includes ongoing support throughout your plan. Learn more about how it works and if it's available in your state at Ulo's website. LEARN MORE 'TRT stands for Testosterone Replacement Therapy. It's a way of bringing your testosterone levels back into a healthy range when your body isn't producing enough. You're not taking extra. You're restoring what your system is missing,' Patel, who co-founded telehealth startup Ulo, explained. Patel says that when TRT is done right, it can give you your life back. A 2019 study on prescription testosterone found that 52% of men claimed testosterone improved their energy, 42% saw improvements in their libido, and 29% reported muscle growth. 7 irantzuarb – While TRT has exhibited a range of benefits, Patel is also open about some of the potential risks. He explained that some of the more common side effects include acne, water retention, or elevated red blood cell counts, which can thicken your blood. Some men experience testicular shrinkage or reduced fertility. Currently, TRT is only FDA-approved for specific conditions, such as a testosterone deficiency (also called hypogonadism) or diminished functional activity of the gonads. In order to start TRT, men will need to get a prescription for testosterone, which requires a blood test. There are a few important steps, but getting an online testosterone prescription is actually much easier than it might appear, thanks to modern telemedicine. Today, those interested in starting TRT can get evaluated, tested, and prescribed TRT right from their laptops, through online TRT clinics like Ulo. How do you get a testosterone prescription online? To piece together the steps needed to get a testosterone prescription online, the Post consulted several medical experts and leaders in the TRT space. Below, find our expert-backed, step-by-step guide. 1. Research reputable online TRT clinics 7 Nattakorn – Tomo Marjanovic is the owner of Aspire Rejuvenation Clinic, a wellness center specializing in personalized hormone therapy and holistic wellness solutions. Before starting your search, it's important to make note of regulations. In the U.S., a provider must be licensed in the patient's state to legally prescribe testosterone. Finding a reputable clinic doesn't stop at that. Marjanovic explained that it's important to look for a TRT clinic that connects patients with licensed medical providers and offers a multi-step process to ensure clients have the information they need before making a decision. 'The clinic should require comprehensive labs, a detailed intake process, and a real conversation with a knowledgeable provider,' explained Marjanovic. 'If the only interaction is an automated signup form or a rushed consult, that's a big red flag.' There are a few other red flags to look out for, according Marjanovic. He recommends skipping any sites that don't require bloodwork and consultations before providing. Clinics should always create individualized plans for treatement and monitor symptoms along the way. A telehealth platform that focuses more on marketing than medicine is also best avoided: 'If it feels more like ordering supplements than receiving medical treatment, it's a problem,' he added. Most reputable telehealth clinics will offer testosterone treatment in the form of injections, tablets, creams, or all of the above. 2. Complete the intake form, considering all symptoms and medical history Before you take a blood test, most reputable online TRT clinics will ask for detailed background information through a medical intake form. Patients should expect several questions about their symptoms, medical history, and lifestyle habits, such as exercise, diet, and drug use. Deep Patel, who is the co-founder of Ulo, emphasized that patients may experience a range of different symptoms. It's important to flag any internal signals, as well as external signs of a hormone deficiency. 'Common symptoms include constant fatigue even when you're sleeping enough, low sex drive, trouble focusing, mood swings or irritability, loss of muscle or strength despite working out, increased belly fat, and even depression or anxiety,' Patel described. At Ulo, the intake form is pretty straightforward. Patients are asked about medical issues, conditions, or previous diagnoses, such as elevated blood pressure or a history of cancer. There are also some questions regarding fertility, which Patel points out is important to consider. TRT significantly suppresses natural testosterone production, which can also reduce sperm production. 'If fertility matters to you, there are medications like HCG or enclomiphene that can be taken alongside TRT to preserve it,' Patel explained. 'Just make sure your provider knows that's a priority from the beginning.' It might be tempting to rush through an intake form, but it's quite important to pay attention to these questions as your responses will dictate the type of treatement that is best for you. 3. Get your bloodwork done, measuring total and free testosterone 7 Pixelbliss – Prior to getting a prescription for testosterone, patients are required to submit bloodwork for analysis. Online clinics have simplified the process by offering at-home test kits that can be delivered straight to your door and mailed back to the lab for review. At-home tests typically require a quick finger prick, but each kit has different instructions, so it's important to read them carefully. If at-home testing is not for you, it's also possible to take a blood test through local lab partnerships, such as Quest or Labcorp. Blood tests can measure different hormone levels, but for a TRT prescription, the primary indicators and total testosterone in your blood. Most testosterone is bound to different proteins, like sex hormone-binding globulin and albumin. However, some testosterone remains unbound, also called 'free testosterone.' Other hormones to consider testing for include estradiol, thyroid, are cortisone. The majority of TRT clinics consider normal testosterone levels to land anywhere between 300 to 1,000 nanograms per deciliter. However, this is just a baseline, and the experts we spoke to have pointed out that the numbers alone don't tell the whole story. 'Some men experience symptoms at 400 or 500 ng/dL if their free testosterone or androgen sensitivity is off. Diagnosis should never rely on numbers alone,' explained Marjanovic. 4. Meet with a licensed provider to discuss your background, ask questions, and clarify risks 7 Kamitana – Receiving an online testosterone prescription should not happen without a conversation. Speaking to a board-certified Doctor is crucial, according to Michael Aziz, the author of 'The Ageless Revolution' and a regenerative physician specialist at Lenox Hill Hospital in NYC. Patients should always confirm their doctor's expertise and education as it relates to testosterone therapy. Perferably, the physician on the call should specialize in endocrinology, urology, and internal medicine with anti-aging training. 'To have an accurate diagnosis, a detailed medical history and exam should be conducted. A Zoom call or telemedicine should be conducted,' Aziz explained. 'The doctor should take into consideration a complete review of symptoms… The clinic's approach to TRT should be comprehensive rather than just giving a script for testosterone treatment.' This consultation provides an opportunity for patients to discuss their goals and ask any questions they might have, but Doctors should also clarify any issues raised through the intake form or bloodwork. It's also a good time to discuss the risks and benefits of different forms of treatement. 'The delivery method of TRT is best chosen by both the doctor and the patient based on the patient's lifestyle and symptoms,' Aziz suggested. 'Gels are used daily, but can be transferred to sexual partners and children. Injections can be self-injected once to twice a week, or administered by the doctor every 10 weeks.' After weighing all the options, the provider will create a personalized treatement plan for the patient. 5. Get your testosterone prescription and begin treatment; follow-up to report progress and side effects 7 OleCNX – At companies like Ulo, the process for starting TRT is straightforward and streamlined. Once a patient receives their prescription, treatement can be sent to their door in as little as a week. However, the one-on-one care doesn't stop when they start taking it. 'We rely on data and feedback from the patient. Your physician will examine your blood work and any changes in symptoms, and will ask how you're feeling in general,' Patel shared. At Ulo, the first lab takes place before your initial consultation with the doctor. A second lab is done 30 days after treatment begins to help prepare for your 45-day follow-up. After that, labs are required every quarter and are paired with a live consultation to make sure your treatment stays safe, effective, and personalized. 'If something seems off or if you're not progressing as expected, the team at Ulo will make adjustments to dosage, frequency, or support meds. Everything can be fine-tuned. The goal is to ensure you feel your best,' Patel explained. As with any treatement plan, it's possible that your tesosterone prescription will need to be altered over time. Be sure to report any progress, concerns, or questions to your provider. This article was written by Miska Salemann, New York Post Commerce Writer/Reporter. As a health-forward member of Gen Z, Miska seeks out experts to weigh in on the benefits, safety and designs of both trending and tried-and-true fitness equipment, workout clothing, dietary supplements and more. Taking matters into her own hands, Miska intrepidly tests wellness products, ranging from Bryan Johnson's Blueprint Longevity Mix to home gym elliptical machines to Jennifer Aniston's favorite workout platform – often with her adorable one-year old daughter by her side. Before joining The Post, Miska covered lifestyle and consumer topics for the U.S. Sun and The Cannon Beach Gazette.
Medscape
4 days ago
- Health
- Medscape
Adherence to Male Hypogonadism Treatment Guidelines Is Low
SAN FRANCISCO — Adherence to diagnostic and treatment guidelines for male hypogonadism is quite low, with significant differences among medical specialists, a new study found. Off-label use of testosterone replacement therapy (TRT) has risen in recent years, corresponding with the advent of direct-to-consumer (DTC) advertising for TRT and the emergence of 'low T' clinics, Petra Pederson, MD, PhD, chief resident in internal medicine at Scripps Clinic/Green Hospital, San Diego, said at the ENDO 2025: The Endocrine Society Annual Meeting. 'This led to our hypothesis that [DTC] advertising in the presence of online clinics creates patient expectations that make it challenging for clinicians to practice evidence- and guideline-based care,' she said. Pederson and colleagues conducted a two-part study of adherence to TRT prescribing guidelines at their institution. The first part involved a retrospective chart review of 269 men who were prescribed TRT from January 1, 2019, through June 30, 2023, examining adherence to the 2018 Endocrine Society clinical practice guideline (CPG). Of the 269 TRT prescriptions, 67.3% were from primary care providers (54% internal medicine and 13% family medicine) and 32.7% from specialists (25% urology and 8% endocrinology). The majority of patients (72.1%) stayed on treatment for at least 1 year, with an average treatment duration of 25 months. Criteria for adherence was defined as: Confirmation of the diagnosis of hypogonadism with two separate low (< 264 ng/dL) early morning total testosterone levels. Determination of the etiology of hypogonadism by measuring luteinizing hormone (LH) and follicle-stimulating hormone (FSH) with appropriate laboratory or imaging follow-up based on the results. On-treatment therapeutic monitoring with total testosterone levels drawn at 3-6 months and 12 months. On-treatment safety monitoring, with hematocrit at baseline and at 3-6 months, with dose reduction if necessary and discontinuation if > 54%. Overall, the proportion of clinicians, primary care, and specialists combined who followed all four criteria was just 5.9%. The difference between primary care (3.3%) and specialists (11.4%) was statistically significant ( P = .009). By individual criteria, 17.8% overall had no low testosterone level prior to treatment, 21% among the primary care group vs 10.2% for the specialists. This difference was also significant ( P = .023). Follow-up total testosterone measurement at 3-6 months was performed for only 50% overall, 44.1% by primary care, and 62.5% by the specialists. Hematocrit testing at 3-6 months was measured at 54% overall, 48.0% by the primary care, and 65.3% by specialists. Both specialty differences were again significant ( P = .01 and P = .06, respectively). Between the two specialties, endocrinologists were more likely than urologists to follow all four criteria, 23.8% vs 7.5%, respectively ( P = .054), and were much more likely to have LH and FSH drawn (85.7% vs 16.4% for LH; P < .001). 'We postulate that these striking differences between endocrinology and urology could be related to the fact that urologists were seeing more patients who present with sexual dysfunction compared to endocrinologists, and perhaps they have more pressure to prescribe,' Pederson said. Barriers: DTC Advertising, Misinformation, Test Inaccuracy The second part of the study involved a survey to which 51 Scripps providers responded. Of those, 74% were primary care (41% internal medicine and 33% family medicine), 18% endocrinologists, and 8% urologists. All 51 reported having seen one or more patients in the last 6 months who requested TRT. The specialists were significantly more likely to report being comfortable with the guidelines than were the primary care providers and to prescribe TRT more often. A total of 74.5% overall felt that DTC advertising and testosterone 'clinics' were significant public health issues. A similar majority (76.5%) felt there was a need for more educational tools. Barriers to providing guideline-based care identified by the providers included misinformation through advertising or social media, for-profit 'low T' clinics that contradict evidence-based guidelines, patient dissatisfaction when guidelines don't align with their expectations, vague and subjective symptoms, and test inaccuracy and variability. 'We're planning to address this at our institution with a quality improvement initiative,' Pederson said. She acknowledged that the American Urological Association guidelines use a low testosterone cutoff of < 300 ng/dL, 'so we might underestimate guideline adherence with our criteria.' And she noted that a small number of primary care providers accounted for a disproportionate number of the prescriptions in their sample, which could limit generalizability. In response to a question from the audience about why the guideline adherence was so low even among specialists, Pederson responded, 'I think that they're experiencing some of the same challenges that PCPs are experiencing, which is the pressure from their patients, and also maybe issues related to tests and accuracy. And I just think the difficulty of getting patients to do all these follow-up tests when they're looking for a simple fix.' Improvements Are Underway, Patient Education Is Key Asked to comment, the Endocrine Society's CPG lead author Shalender Bhasin, MB, professor of medicine at Harvard Medical School and director of the Research Program in Men's Health: Aging and Metabolism at Brigham and Women's Hospital, Boston, told Medscape Medical News that these findings align with those of a study his group conducted a decade ago in the Veterans Administration (VA), but that the VA has since implemented system-wide improvements. 'I think it's gotten much better. In the VA, it was very low, and it has gotten substantially better because at the VA now there's one policy. Also, the assays have gotten better.' Bhasin also pointed out that the prescribing of testosterone has fluctuated over time, dropping in 2013 after an FDA advisory about cardiovascular risk but then rising again around 2017 following the TRAVERSE trial results showing cardiovascular safety. The subsequent rise has been slower, but, Bhasin noted, 'testosterone sales are growing, and at the same time, many men with testosterone deficiency remain undiagnosed, so it's both overuse and underuse.' Also asked to comment, session moderator Ismat Shafiq, MD, of the University of Rochester, Rochester, New York, told Medscape Medical News that patients will commonly have low total testosterone due to overweight or obesity and/or sleep apnea but will have normal free testosterone. 'If that's the case, we can properly educate our patients and work on managing their weight and sleep problems. That can reverse the hypogonadism and make them feel better, rather than giving them testosterone.' And if they have both low total and free testosterone, the cause could be something reversible, such as a prolactinoma or pituitary macroadenoma. 'If we check the prolactin level and we treat them, the hypogonadism will resolve. Primary hypothyroidism, too, if treated, can resolve the hypogonadism,' Shafiq said. 'Diagnosing the patient appropriately can identify causes that can be treatable and that can improve their quality of life and improve their testosterone level too, rather than jumping into giving them testosterone.' She also noted that many patients mistakenly believe that more testosterone is better. 'We need to educate them. In my experience, most of the patients listen and understand because nobody wants to take extra medicine all the time, unless it's really needed for them to improve their quality of life.' Pederson and Shafiq reported having no disclosures. Bhasin reported receiving research grant support from AbbVie and Metro International Biotech for investigator-initiated research, with the grants managed by Brigham and Women's Hospital. He has served as a consultant to Besins and Versanis and has an equity interest in XYone Therapeutics.
