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South Wales Argus
3 days ago
- Health
- South Wales Argus
Mounjaro 'golden dose' revealed to stop 'food noise'
One major insight from the data is that users don't need the maximum dose to succeed - the so-called 'golden dose' may be much lower. Meaningful weight loss can be achieved at all levels, and results can vary between individuals, as 'food noise' is reduced. Patient dosage, starting body mass index (BMI) and percentage of body weight lost were reviewed, to provide people exploring treatment a realistic snapshot of what to expect and show what real success looks like. Mounjaro users report surprising side effect - pharmacists share their tips — Telegraph & Argus (@Bradford_TandA) August 5, 2025 Leading online pharmaceutical company Oxford Online Pharmacy has conducted a study of 100 anonymised patients prescribed once-weekly Mounjaro (tirzepatide) injections. The data aims to counteract unhealthy beliefs that hunger equals failure, which may lead to unnecessary concerns and calls for increased doses. The analysis revealed that patients in the analysis lost up to 39kg, with consistent results across a range of doses. Kiran Jones, Clinical Pharmacist at Oxford Online Pharmacy, says: 'This study reinforces that healthy, sustainable weight loss is possible without excessive pressure or maximal dosing. 'People think these medicines switch off hunger completely, but that's not how they work. Being able to eat is normal. Success looks different for everyone, and often, the biggest wins are quiet ones: more energy, less breathlessness, and better sleep. 'Becoming healthier without extreme diets or private clinics is a powerful example of what good, regulated care can achieve. Patients need safety, not pressure.' All patients started on the recommended dose of 2.5mg, which gradually increased depending on individual response (up to 12.5mg), with 86% maintaining a moderate dose of 10mg or lower. The most common dose for over half of the patients was 5mg. It varies for everyone, but I did 6 months of Mounjaro and "I feel absolutely starving when I don't eat enough" was 100% gone. However, dosing is poorly managed. They wanted to increase all the time and that made me sick, so I stayed on the lowest dose and it worked great. — Peter Cooper (@cooperx86) August 5, 2025 Weight loss generally increased with dose, but the data shows this does not follow a strictly linear pattern. Patients on 7.5mg showed the highest average weight loss overall, showing smaller doses can be effective, and making this the 'golden dose' for many people. Similarly, higher BMI correlated with greater weight loss, but not in all patients. The study also highlights the importance of celebrating non-weight loss wins, discussing how the right dose helps users strike a balance between appetite control, tolerability and overall wellbeing. However, the experts say that they should not switch off hunger entirely - it just helps regulate appetite and increase feelings of satisfaction. Being able to enjoy food can be a sign that the medicine is working appropriately. Meanwhile, before experiencing weight loss, patients reported improvements, including better sleep, more stable energy and mood, reduced cravings, and increased motivation to move. What is 'food noise'? 'Food noise' is thinking about food even when you aren't physically in need of food. Experts say it is a psychologically driven process, unlike real hunger, which comes from your body needing nutrients and fuel. GP registrar Dr Jack Mosley – whose dad was BBC presenter Dr Michael Mosley - has written a book titled Food Noise. Recommended reading: "There's multiple reasons we eat," he says. "One of the big drivers is simply appetite, and that's centrally controlled in our brain and through our guts. "But our cravings – that internal food monologue, which I refer to as the 'food noise' – that can be turned up if you are hungry, but plenty of people, eat even when they're not hungry. "Many of us can relate to it, when we're stressed, we're not typically eating nutritious foods. We want that easy, accessible junk food. So we want the sugary, salty snacks. We want that sugar high. The weight-loss drugs can reduce our appetite and our cravings, but they're not necessarily going to address things like our emotional hunger."
Glasgow Times
4 days ago
- Health
- Glasgow Times
Mounjaro 'golden dose' revealed to stop 'food noise'
One major insight from the data is that users don't need the maximum dose to succeed - the so-called 'golden dose' may be much lower. Meaningful weight loss can be achieved at all levels, and results can vary between individuals, as 'food noise' is reduced. Patient dosage, starting body mass index (BMI) and percentage of body weight lost were reviewed, to provide people exploring treatment a realistic snapshot of what to expect and show what real success looks like. Mounjaro users report surprising side effect - pharmacists share their tips — Telegraph & Argus (@Bradford_TandA) August 5, 2025 Leading online pharmaceutical company Oxford Online Pharmacy has conducted a study of 100 anonymised patients prescribed once-weekly Mounjaro (tirzepatide) injections. The data aims to counteract unhealthy beliefs that hunger equals failure, which may lead to unnecessary concerns and calls for increased doses. The analysis revealed that patients in the analysis lost up to 39kg, with consistent results across a range of doses. Kiran Jones, Clinical Pharmacist at Oxford Online Pharmacy, says: 'This study reinforces that healthy, sustainable weight loss is possible without excessive pressure or maximal dosing. 'People think these medicines switch off hunger completely, but that's not how they work. Being able to eat is normal. Success looks different for everyone, and often, the biggest wins are quiet ones: more energy, less breathlessness, and better sleep. 'Becoming healthier without extreme diets or private clinics is a powerful example of what good, regulated care can achieve. Patients need safety, not pressure.' All patients started on the recommended dose of 2.5mg, which gradually increased depending on individual response (up to 12.5mg), with 86% maintaining a moderate dose of 10mg or lower. The most common dose for over half of the patients was 5mg. It varies for everyone, but I did 6 months of Mounjaro and "I feel absolutely starving when I don't eat enough" was 100% gone. However, dosing is poorly managed. They wanted to increase all the time and that made me sick, so I stayed on the lowest dose and it worked great. — Peter Cooper (@cooperx86) August 5, 2025 Weight loss generally increased with dose, but the data shows this does not follow a strictly linear pattern. Patients on 7.5mg showed the highest average weight loss overall, showing smaller doses can be effective, and making this the 'golden dose' for many people. Similarly, higher BMI correlated with greater weight loss, but not in all patients. The study also highlights the importance of celebrating non-weight loss wins, discussing how the right dose helps users strike a balance between appetite control, tolerability and overall wellbeing. However, the experts say that they should not switch off hunger entirely - it just helps regulate appetite and increase feelings of satisfaction. Being able to enjoy food can be a sign that the medicine is working appropriately. Meanwhile, before experiencing weight loss, patients reported improvements, including better sleep, more stable energy and mood, reduced cravings, and increased motivation to move. What is 'food noise'? 'Food noise' is thinking about food even when you aren't physically in need of food. Experts say it is a psychologically driven process, unlike real hunger, which comes from your body needing nutrients and fuel. GP registrar Dr Jack Mosley – whose dad was BBC presenter Dr Michael Mosley - has written a book titled Food Noise. Recommended reading: "There's multiple reasons we eat," he says. "One of the big drivers is simply appetite, and that's centrally controlled in our brain and through our guts. "But our cravings – that internal food monologue, which I refer to as the 'food noise' – that can be turned up if you are hungry, but plenty of people, eat even when they're not hungry. "Many of us can relate to it, when we're stressed, we're not typically eating nutritious foods. We want that easy, accessible junk food. So we want the sugary, salty snacks. We want that sugar high. The weight-loss drugs can reduce our appetite and our cravings, but they're not necessarily going to address things like our emotional hunger."
Daily Mirror
13-06-2025
- Daily Mirror
'We woke up on dream Turkey holiday to screams of terror - I couldn't breathe'
British pensioners tell how they feel 'lucky to be alive' after escaping horrific blaze at their hotel during a holiday in Turkey. They didn't think they would make it back to the UK in one piece Daniel and Christine Steel, who are both nearly 70, had been enjoying a break at a five-star resort in Turkey when a terrifying fire broke out. The pensioners were among six people taken to hospital for smoke inhalation and Daniel said at one point during the nightmare, he phoned his daughter because he didn't think they'd be coming home alive. Daniel from Bradford told his local paper the Telegraph & Argus: "We feel lucky to be alive. We were woken up after hearing screams of 'fire, fire' and 'help, help!' Our room became dense with smoke - we couldn't breathe. "We were on the top floor and had to make a decision about what to do. Put it this way, if it wasn't for the balcony, we wouldn't be here now telling you this story. Below us was a 250ft drop and it was pitch black - all the electricity went off because of the fire." The couple climbed over the balcony rails onto a roof and held onto the rails for 'dear life'. But pensioner Daniel pulled a nerve in his leg and is still in a lot of pain. "Most of the hotel was evacuated but we came across some other guests who found themselves in the same position as us," he continued. "At that point, there were 11 of us screaming for help. We were eventually rescued by firefighters after what felt like a lifetime." After leaving hospital, they were moved to alternative accommodation before later returning to the hotel to collect their belongings. But Daniel said all their holiday things were ruined. And although the couple are glad to be back home, Christine is still struggling to forget about their hellish experience. She added: "We keep reliving what happened - and thinking what might have happened if we hadn't had a balcony. It was certainly a holiday from hell - but we're grateful to be alive."
Scottish Sun
07-05-2025
- Entertainment
- Scottish Sun
Comedy duo's huge Sky show is axed after just one series following ratings flop
Click to share on X/Twitter (Opens in new window) Click to share on Facebook (Opens in new window) HE built a comedy career out of mocking the press, now Nish Kumar has seen his own bid at being a newspaper reporter fall at the first hurdle. The comedian joined fellow funnyman Josh Widdicombe on Hold the Front Page, which last aired in 2024, which saw them see what it was like to be a hack. 1 Comedians Josh Widdicombe and Nish Kumar on Hold the Front Page But after a pretty mediocre response to the six-part show, bosses at Sky Max have decided to drop the axe - with no plans for another season. A TV insider said: "The irony of the scenario is not lost on the creative team behind the show, because as a comedian involved in satire Josh is often making swipes at the media. "But he got a taste of what its like to have to report on what's going on and realised just what a tough job it can be - particularly when you have to start out in the local press." Nish, best known for fronting The Mash Report on BBC Two, joined all-round funnyman Josh on a jaunt round the country where they found themselves in multiple newspaper offices. It included stopping off in Bradford to spend time on the city's Telegraph & Argus where they reported on everything from a church of wrestling to extra hot curries and the local opera scene. They also visited Josh's home county of Devon where they got down and dirty on the mud to report for The Moorlander newspaper, bringing news to over 100,000 people in the area. They also went on the hunt of an escaped prisoner and attended a local sci-fi convention. The duo even ended up in sunny Benidorm where they worked on the Euro News bringing stories to expats wanting to keep informed. But the reviews and the viewing figures were generally poor and their brief foray into journalism has now come to an abrupt end. Shame. Sky were approached for comment.
The Irish Sun
07-05-2025
- Entertainment
- The Irish Sun
Comedy duo's huge Sky show is axed after just one series following ratings flop
HE built a comedy career out of mocking the press, now Nish Kumar has seen his own bid at being a newspaper reporter fall at the first hurdle. The comedian joined fellow funnyman Advertisement 1 Comedians Josh Widdicombe and Nish Kumar on Hold the Front Page But after a pretty mediocre response to the six-part show, bosses at Sky Max have decided to drop the axe - with no plans for another season. A TV insider said: "The irony of the scenario is not lost on the creative team behind the show, because as a comedian involved in satire Josh is often making swipes at the media. "But he got a taste of what its like to have to report on what's going on and realised just what a tough job it can be - particularly when you have to start out in the local press." Advertisement READ MORE TV NEWS It included stopping off in Bradford to spend time on the city's Telegraph & Argus where they reported on everything from a church of wrestling to extra hot curries and the local opera scene. They also visited Josh's home county of Devon where they got down and dirty on the mud to report for The Moorlander newspaper, bringing news to over 100,000 people in the area. They also went on the hunt of an escaped prisoner and attended a local sci-fi convention. The duo even ended up in sunny Benidorm where they worked on the Euro News bringing stories to expats wanting to keep informed. Advertisement Most read in News TV But the reviews and the viewing figures were generally poor and their brief foray into journalism has now come to an abrupt end. Shame. Sky were approached for comment. Chaos at Lord's Taverners' Christmas charity lunch as comedian Nish Kumar is booed off and hit with a BREAD ROLL
