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NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024
NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

Yahoo

timea day ago

  • Business
  • Yahoo

NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

NextCure, Inc. (NASDAQ:NXTC) and LigaChem Biosciences, Inc. are set to present new clinical data on their novel cancer therapy, LNCB74, at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on June 2, 2025. LNCB74 is a first-in-human, B7-H4 targeted antibody-drug conjugate (ADC) currently being evaluated in a Phase 1 trial for patients with advanced solid tumors, including platinum-resistant ovarian, treatment-refractory breast, endometrial, biliary tract, and squamous non-small cell lung cancers. A scientist in a lab researching the biology of a cancer cell. The ongoing study is in the dose escalation phase and will also include randomized dose expansion and optimization, with an emphasis on safety and biomarker analysis. B7-H4, the ADC's target, is highly expressed in several tumor types but limited in normal tissues, making it an appealing candidate for targeted therapy. According to NextCure, Inc. (NASDAQ:NXTC)'s Chief Medical Officer, Dr. Udayan Guha, LNCB74 has shown a superior safety profile and potent anti-tumor activity in preclinical models. The poster, abstract TPS3167, will be featured during the 'Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology' session. NXTC closed nearly 6% higher on May 29. While we acknowledge the potential of NXTC to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than NXTC and that has 100x upside potential, check out our report about this READ NEXT: and Disclosure: None.

NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024
NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

Yahoo

timea day ago

  • Business
  • Yahoo

NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

NextCure, Inc. (NASDAQ:NXTC) and LigaChem Biosciences, Inc. are set to present new clinical data on their novel cancer therapy, LNCB74, at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on June 2, 2025. LNCB74 is a first-in-human, B7-H4 targeted antibody-drug conjugate (ADC) currently being evaluated in a Phase 1 trial for patients with advanced solid tumors, including platinum-resistant ovarian, treatment-refractory breast, endometrial, biliary tract, and squamous non-small cell lung cancers. A scientist in a lab researching the biology of a cancer cell. The ongoing study is in the dose escalation phase and will also include randomized dose expansion and optimization, with an emphasis on safety and biomarker analysis. B7-H4, the ADC's target, is highly expressed in several tumor types but limited in normal tissues, making it an appealing candidate for targeted therapy. According to NextCure, Inc. (NASDAQ:NXTC)'s Chief Medical Officer, Dr. Udayan Guha, LNCB74 has shown a superior safety profile and potent anti-tumor activity in preclinical models. The poster, abstract TPS3167, will be featured during the 'Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology' session. NXTC closed nearly 6% higher on May 29. While we acknowledge the potential of NXTC to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than NXTC and that has 100x upside potential, check out our report about this READ NEXT: and Disclosure: None.

NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024
NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

Yahoo

timea day ago

  • Business
  • Yahoo

NextCure, Inc. (NXTC) and LCB to Unveil Promising Preclinical Data on B7-H4 ADC at AACR 2024

NextCure, Inc. (NASDAQ:NXTC) and LigaChem Biosciences, Inc. are set to present new clinical data on their novel cancer therapy, LNCB74, at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago on June 2, 2025. LNCB74 is a first-in-human, B7-H4 targeted antibody-drug conjugate (ADC) currently being evaluated in a Phase 1 trial for patients with advanced solid tumors, including platinum-resistant ovarian, treatment-refractory breast, endometrial, biliary tract, and squamous non-small cell lung cancers. A scientist in a lab researching the biology of a cancer cell. The ongoing study is in the dose escalation phase and will also include randomized dose expansion and optimization, with an emphasis on safety and biomarker analysis. B7-H4, the ADC's target, is highly expressed in several tumor types but limited in normal tissues, making it an appealing candidate for targeted therapy. According to NextCure, Inc. (NASDAQ:NXTC)'s Chief Medical Officer, Dr. Udayan Guha, LNCB74 has shown a superior safety profile and potent anti-tumor activity in preclinical models. The poster, abstract TPS3167, will be featured during the 'Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology' session. NXTC closed nearly 6% higher on May 29. While we acknowledge the potential of NXTC to grow, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an AI stock that is more promising than NXTC and that has 100x upside potential, check out our report about this READ NEXT: and Disclosure: None. Error in retrieving data Sign in to access your portfolio Error in retrieving data Error in retrieving data Error in retrieving data Error in retrieving data

BJP vs Trinamool Over Bengal Minister's 'Operation Sindoor' Remark
BJP vs Trinamool Over Bengal Minister's 'Operation Sindoor' Remark

NDTV

time2 days ago

  • Politics
  • NDTV

BJP vs Trinamool Over Bengal Minister's 'Operation Sindoor' Remark

Kolkata: Senior Trinamool Congress leader and West Bengal Minister Udayan Guha has sparked a row by taking a veiled dig at Prime Minister Narendra Modi and 'Operation Sindoor'. Addressing an event in Dinhata in Cooch Behar district on Tuesday, Guha, the Minister for North Bengal Development, said, "those who once sold tea are now doing business in vermilion." However, PTI couldn't independently verify the authenticity of the video. The remarks drew a sharp backlash from the BJP, which accused Mr Guha of insulting India's armed forces and undermining the spirit of 'Operation Sindoor', which was launched by India against Pakistan on May 7 in response to the April 22 Pahalgam terror attack. Bengal BJP president Sukanta Majumdar strongly condemned the remarks and demanded Mr Guha's removal from the state cabinet. "Udayan Guha has made a comment that is not only utterly condemnable but amounts to treason," Majumdar said. "At a time when the entire nation is celebrating the success of 'Operation Sindoor', a minister in the West Bengal government is saying that 'sindoor' is being sold as a business. This is an insult to every person who was killed in the terrorist attack in Pahalgam and India's security forces. For such a disgraceful and reprehensible comment, Chief Minister Mamata Banerjee must remove Guha from the cabinet," he said. In a post on X, the West Bengal BJP said, "TMC Minister Udayan Guha stoops to new lows, mocking PM Modi's humble beginnings, belittling Indian Army's valour, and branding 'Operation Sindoor' against Pakistani terrorists as a 'Sindoor business' and a 'religious stunt.' This isn't a slip, it's a calculated insult to every soldier and citizen." As of Wednesday evening, the Trinamool Congress had not issued any official response to the controversy. Prime Minister Modi is scheduled to address a public rally in Alipurduar on Thursday as part of the BJP's campaign in Bengal.

Comment amounts to treason: Sukanta Majumdar hits out at Udayan Guha for his statement on PM Modi, Operation Sindoor
Comment amounts to treason: Sukanta Majumdar hits out at Udayan Guha for his statement on PM Modi, Operation Sindoor

India Gazette

time2 days ago

  • Politics
  • India Gazette

Comment amounts to treason: Sukanta Majumdar hits out at Udayan Guha for his statement on PM Modi, Operation Sindoor

Kolkata (West Bengal) [India], May 28 (ANI): In the wake of TMC Minister Udayan Guha taking a jibe at Prime Minister Narendra Modi over his statement in Bikaner on 'Operation Sindoor', Union Minister and West Bengal BJP President Sukanta Majumdar said that comment by Guha amounted to treason. PM Modi on May 22 asserted that India, after Operation Sindoor, made it clear that Pakistan will have to pay a heavy price for every terrorist attack and said that 'there is no blood flowing in Modi's veins, but hot Sindoor.' In a post on X, Sukanta Majumdar said, 'Udayan Guha, a key member of Mamata Banerjee's cabinet and the Minister for North Bengal Development, has made a comment that is not only utterly condemnable but amounts to treason! At a time when the entire nation is celebrating the success of #OperationSindoor --an operation launched by the Indian Armed Forces to appropriately punish Pakistan-sponsored radical Islamist terrorists--Udayan Guha, a minister in the West Bengal government, is saying that 'Sindoor is being sold as a business.' Such behavior cannot simply be dismissed as perverse; it is an insult to every martyr who was killed in the Islamist terrorist attack in Pahalgam, an insult to India's security forces!' Sukanta Majumdar said that in his desperation to insult the Prime Minister, the Trinamool minister from North Bengal has not hesitated to insult the entire nation. 'Those who refer to the counter-terror operations of our brave soldiers--the very soldiers who keep our country safe through tireless dedication and fearless vigilance--as 'business' have no moral right to live in this country! For such a disgraceful and reprehensible comment, the Chief Minister of West Bengal @MamataOfficial must immediately remove Udayan Guha from the cabinet,' he said. 'North Bengal is not only vital for Bengal but also one of the most strategically sensitive regions for the security of the entire country. If the Minister for North Bengal Development himself speaks in support of anti-nationals, it is a grave concern for national security,' he further shared. In a post on X, BJP West Bengal shared that TMC Minister Udayan Guha had stooped to new low. BJP West Bengal shared, 'TMC Minister Udayan Guha stoops to new lows -- mocking PM Modi's humble beginnings, belittling Indian Army's valor, and branding Operation Sindoor against Pakistani terrorists as a 'Sindoor business' and a 'religious stunt.' This isn't a slip -- it's a calculated insult to every soldier and citizen. But Mamata won't dare touch him. Why? Because Udayan Guha is her goon-master in North Bengal -- the man who spreads terror, unleashes violence, and rigs democracy through fear. His family's legacy? Party-hopping, vote suppression, and political thuggery. No wonder Mamata shields him -- thugs are prized assets in her toolkit of tyranny.' Earlier, without mentioning PM Modi's name, Udayan Guha took a jibe at him. 'Someone used to sell tea earlier, now they have started selling Sindoor. Earlier, they used to sell hot tea, now hot Sindoor is flowing through their veins,' he said. (ANI)

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