Latest news with #WCM-Q
Qatar Tribune
18-05-2025
- Health
- Qatar Tribune
WCM-Q probes link between insulin resistance and colorectal cancer
Tribune News Network Doha Researchers at Weill Cornell Medicine-Qatar (WCM-Q) have explored the possible links between insulin resistance and early-onset colorectal cancer (EOCRC) in a new article published in Cancer Cell (Cell Press), a leading scientific journal. Cancer, regardless of type, is generally considered a disease that occurs later in life, typically after 50-60 years of age. Data from the Surveillance, Epidemiology, and End Results (SEER) Programme of the National Cancer Institute (NCI), USA, indicates that the median age of a cancer diagnosis is 66. However, more recently, younger individuals under the age of 45-50 have been diagnosed with cancers (early-onset cancers; EOCs). Although this shifting trend in cancer epidemiology has been reported previously, this occurrence gained significant attention in early 2024, with many major news outlets and research/medical institutions reporting a rise in EOCs. Among the various EOCs, gastrointestinal cancers, particularly colorectal cancer (CRC), seem to be rapidly increasing among the younger population. This trend appears similar for countries in the MENA region, including Qatar. 'As cancer researchers, we were captivated by the question of 'why this is happening?'' said Prof. Dietrich Büsselberg, professor of physiology and biophysics, one of the co-corresponding authors of the article. 'It is well known that genetic mutations that cause CRC and hereditary CRC-associated syndromes are highly penetrant and increase the risk of CRC. However, it is unlikely that this risk factor alone has changed so dramatically in successive generations of the population to account for the significant increase in EOCRC in recent years.' Dr. Samson Mathews Samuel, research associate in physiology and biophysics and co-corresponding author of the article, said: 'Our in-depth review of existing literature led us to identify a possible culprit behind this occurrence, namely insulin resistance.' A growing body of evidence points to insulin resistance, a hallmark of common metabolic diseases such as obesity, diabetes, and metabolic syndrome, as a possible key risk factor contributing to the incidence and progression of EOCRC. Insulin resistance, defined as the inability of cells to respond to normal insulin, results in hyperinsulinemia (an increase in circulating insulin levels in the blood) much earlier in life than is typically recognized. Surprisingly, insulin resistance can drive metabolic changes very early in life and depends on several early-life external factors to which the individual is exposed. Elizabeth Varghese, a senior research specialist, is the other author of the paper, titled 'Complexity of insulin resistance in early-onset colorectal cancer'. The paper also infers that managing insulin resistance through dietary and/or lifestyle changes and therapeutic interventions is likely to be effective in reducing the incidence of colorectal cancer among young individuals.
Qatar Tribune
12-05-2025
- Health
- Qatar Tribune
WCM-Q designated as Centre of Excellence by top diabetes body
Tribune News Network Doha Weill Cornell Medicine-Qatar (WCM-Q) has become the first medical institution in Qatar to receive official designation as an International Diabetes Federation Centre of Excellence for diabetes care, research and education. It joins an elite group of 25 other centres of excellence across the world. To be designated a Centre of excellence, WCM-Q had to meet stringent eligibility criteria set by the International Diabetes Federation, including having state-of-the-art infrastructure for providing education, a track record of high-quality diabetes research, and status as a clinical institution with a multidisciplinary team of health professionals actively involved in diabetes care, prevention and advocacy. The International Diabetes Federation is the global voice of the diabetes community. It is a non-profit umbrella organisation of 251 national diabetes associations in 158 countries and territories, working together to improve and empower the lives of the estimated 590 million people living with diabetes and prevent diabetes in those at risk. Leading WCM-Q diabetes researcher Dr Rayaz Malik, professor of medicine and assistant dean for clinical research partnerships, said: 'We are very pleased to be designated an International Diabetes Federation centre of excellence in recognition of our contribution to global diabetes research and education. 'This strengthens our capacity to undertake research in diabetes and its complications and enables WCM-Q to deliver education to healthcare professionals that will improve the diagnosis and management of people with diabetes and those at risk of developing diabetes. By working closely with organisations like the International Diabetes Federation, we can help prevent the development of diabetes and improve the lives of those with diabetes.' Dr Malik explained that in their recent systematic review published in the Lancet Diabetes Endocrinology, a 20-29 percent weight loss was shown to be associated with partial remission of diabetes in approximately 70 percent of people with type 2 diabetes. Furthermore, regular screening to identify early complications affecting the nerves, eyes and kidneys can prevent or limit blindness, dialysis and amputation. Dr Javaid Sheikh, dean of WCM-Q, said: 'Designation as a Centre of Excellence by the International Diabetes Federation is a great honour for WCM-Q. Diabetes is perhaps the most pressing health concern for our region and WCM-Q is pursuing a multifaceted approach to tackling the condition through world-class research, clinical excellence, educational initiatives, and patient advocacy.'
Qatar Tribune
10-05-2025
- Health
- Qatar Tribune
WCM–Q graduates set sights on global impact
Satyendra Pathak Doha Weill Cornell Medicine–Qatar (WCM-Q), the Ivy League institution's Middle East campus, continues to live up to its reputation as a premier medical school nurturing some of the most promising doctors of tomorrow. As this year's cohort of graduates steps out into the world, each one carries a deeply personal story shaped by determination, diversity, and a shared desire to serve. Among them is Ahamed Lebbe, who moved from Sri Lanka to Qatar at the age of seven. Growing up in Doha, his dream to become a doctor was fueled by the urge to give back to society in a meaningful way. WCM-Q offered him not only a world-class curriculum but also access to US-based clinical experiences that have prepared him for the next chapter: a residency at the renowned Johns Hopkins Hospital. His goal? A career in gastroenterology. For Ahamed, WCM-Q offered the ideal blend: a globally recognised Ivy League education within reach of home. What truly impressed him, he shared, was the institution's strong emphasis on patient-centred care, a philosophy that resonated deeply with his own values. He credits WCM-Q with preparing him for clinical rotations and research opportunities in the United States, which strengthened his residency applications. He is now headed to Johns Hopkins Hospital to begin his residency in internal medicine, with hopes of eventually specialising in gastroenterology. Pradipta Paul, a Bangladeshi national born and raised in Qatar, found his calling early in life. For him, WCM-Q wasn't just an educational institution — it was a bridge between home and a global future. His groundbreaking research on COVID-19 vaccines, under the mentorship of Dr Laith Abu-Raddad, professor of population health sciences, and director of the biostatistics, epidemiology, and biomathematics research core at WCM-Q, won him accolades and helped shape his approach to patient care. His interest in medicine was sparked in high school, and he was determined to pursue it while remaining close to his family. 'WCM-Q allowed me to do what I loved, while staying rooted,' he said. His time at the college helped him develop a strong aptitude for research, which began as early as his second year in the pre-medical track. Over the years, this interest evolved into a deep commitment. He believes this experience not only honed his analytical and communication skills but will also help him counsel patients with vaccine hesitancy in clinical practice. He is now headed to Rochester General Hospital to begin his residency in internal medicine, with ambitions to specialise further in cardiology or gastroenterology. For American-born Kevin Zhai, the choice to study medicine in Qatar was deliberate. Eschewing offers from US schools, he embraced the cultural diversity and intimacy of WCM-Q's campus, where he thrived in leadership roles and led pioneering research in nanomedicine. He will soon begin his residency in neurology in the United States. 'I knew I would receive the same Cornell curriculum here, but with the added benefit of understanding a different culture and healthcare system,' he said. What stood out for Kevin was the more intimate academic environment compared to large US universities. With smaller class sizes and strong faculty access, he found ample opportunities for leadership and innovation. Over the past few years, he led a research team as principal investigator, exploring the intersections of nanotechnology and medicine. His work, funded through various grants and published in peer-reviewed journals, has contributed to a growing body of knowledge in biomedical innovation. He will now return to the US to begin his residency in neurology. Another graduate Mohammad Saad Javed, originally from Pakistan but raised in the UK, has been living in Qatar for the past decade. He joined WCM-Q at a time when it was the sole provider of American-style medical education in the country. Now, with several years of rigorous training behind him, he appreciates the institution's holistic and supportive learning environment. 'The faculty are incredibly engaged. They truly care about student growth,' he shared. Though he didn't highlight a specific research project, he expressed pride in simply completing the programme and stepping into the next phase of his career. He is now preparing to begin his residency in psychiatry in Florida. Then, there's the story of Omar Mourad and Aisha Serpedin — two students whose paths converged both professionally and personally. Amar, a Syrian national raised in Qatar, and Aisha, who moved from the US with her Romanian-American family, were drawn to WCM-Q for similar reasons: the opportunity to receive an American education close to home. They are now headed to the University of Vermont for their residencies with Amar specialising in internal medicine and Aisha in neurology — with plans to return and serve the region they call home. 'There are unique cases and healthcare challenges in this region. Studying medicine here gave me exposure to both American medical standards and local cultural contexts,' Aisha said. For Amar, treating Arabic-speaking patients and practising in a community he knew well was a key motivation. Both valued the professionalism and high standards of education that WCM-Q offered. As fate would have it, their shared journey extended beyond the classroom. The couple matched together at the University of Vermont — Aisha into neurology and Amar into internal medicine. They hope to return to Qatar after their US training to serve the region with their acquired expertise. From aspiring physicians to future specialists in internal medicine, neurology, psychiatry, gastroenterology, and cardiology, these graduates are now set to begin their residencies in top institutions across the United States. They leave behind a legacy of academic excellence, groundbreaking research, and a strong commitment to serve. As they step into the global medical landscape, their stories remain anchored in the halls of Weill Cornell Medicine–Qatar, an institution that has empowered them to heal, to lead, and to inspire.
Al Bawaba
06-05-2025
- Health
- Al Bawaba
WCM-Q Student Research Forum showcases student innovation
Weill Cornell Medicine-Qatar (WCM-Q) recently hosted its second annual Student Research Forum, showcasing 66 impressive scientific posters that demonstrate student innovation and scientific discovery. The forum serves as a platform for WCM-Q students to showcase their research efforts, exchange insights, and engage in meaningful discussions with their peers and faculty members. Attended by students, faculty, staff, and visitors, the one-day event was organized by the Student Research Forum Committee, which includes representatives from the divisions of Research and Medical Education at WCM-Q. The forum began with welcoming remarks from Dr. Ziyad Mahfoud, professor of research in population health sciences, and Dr. Nayef Mazloum, associate professor of microbiology & immunology/associate dean for student research. Both faculty members at WCM-Q. The keynote address was delivered by Professor Hanadi Sleiman, Canada Research Chair in DNA nanoscience at McGill University's Department of Chemistry. A fellow of the Royal Society (FRS) and the Royal Society of Chemistry (FRSC), Prof. Sleiman is a pioneer in DNA nanotechnology. Her groundbreaking work involves designing DNA-based structures for applications in medicine, materials science, and nanotechnology. In her presentation, she explored how DNA nanostructures can be utilized as precision therapies. Following the keynote, WCM-Q alumnus Dr. Tariq Chukir, assistant professor of medicine at WCM-Q, discussed the disparities between obesity management medications in clinical trials and their real-world applications. Dr. Chukir also serves as a consultant at the National Obesity Treatment Centre at Hamad Medical Corporation (HMC). Six oral research presentations were then delivered by students Latifa AlMahmoud, Pradipta Paul, Kevin Zhai, Hasan Alsetri, Nour Jaouni, and Fatima Almusleh. Their topics covered the impact of cyberbullying on adolescents, the effectiveness of mRNA vaccines against pre-Omicron era SARS-CoV-2 infection, and corneal transplant risk factors, among others. The event concluded with the announcement of the winning students in the research contest. Dr. Mahfoud said: 'Research is one of the key pillars for advancing science and improving patient care. We were delighted to once again provide our students with a platform to showcase their research, exchange ideas, and take their research capabilities to the next level.' Dr. Mazloum said: 'This year, we were extremely proud to witness another impressive display of student innovation fueled by inspiring levels of determination and enthusiasm. I would like to sincerely thank our mentors for sharing their valuable expertise, as well as the divisions of Research and Medical Education for their ongoing support.' The winners of the oral presentation awards in the Area of Concentration (AOC) category were Kevin Zhai in first place (mentored by Dr. Evan Noch, UT Southwestern Medical Center), Latifa AlMahmoud in second (mentored by Dr. Ziyad Mahfoud, WCM-Q), and Pradipta Paul in third (mentored by Dr. Laith Abu Raddad, WCM-Q). The winners of the oral presentation awards in the Medical Students Research Award (MSRA) category were Fatima Almusleh in first place (mentored by Dr. Vidya Mohammed Ali, University College London), Hasan Alsetri in second (mentored by Dr. Zeba Syed, Wills Eye Hospital, Philadelphia), and Nour Jaouni in third (mentored by Dr. Teresa Milner, WCM). The winners of the poster presentations awards in the AOC category were Aisha serpedin in first place (mentored by Dr. Anna Halama, WCM-Q), Shadi Mahmoud in second (mentored by Dr. Charbel Abi Khalil, WCM-Q), and Sara Mohamed in third (mentored by Dr. Ahmed Serag, WCM-Q). The poster presentation winners in the MSRA/Advanced Biomedical Sciences Research (ABSR) elective category were Fatima Al Mohammed in first place (mentored by Dr. David Kelsell, Queen Mary University of London), Zoya Salahuddin in second (mentored by Dr. Xiaojing Ma, WCM), and Maryam Al-Musleh in third (mentored by Dr. Nayef Mazloum, WCM-Q).
Qatar Tribune
05-05-2025
- Health
- Qatar Tribune
WCM-Q hosts ‘Doctors of the Future' event for aspiring medical students
Tribune News Network Doha More than 200 pre-university students with ambitions to pursue careers in medicine participated in Weill Cornell Medicine-Qatar's (WCM-Q) two-day Doctors of the Future Conference. Held annually, the conference gives pre-university students the chance to explore WCM-Q's state-of-the-art campus, learn about the college's world-class educational programmes, and discover the wide range of opportunities that can be accessed by studying for a Doctor of Medicine (MD) degree. During the conference, students participated in a variety of activities, including interactive sessions with faculty, current students, and WCM-Q alumni. Highlights included the grand finale of a research contest and panel discussions on topics such as applying to medical school, the life of a medical student, and career pathways in medicine. Attendees also enjoyed talks on pre-college programmes and the fundamentals of research, along with presentations of research posters by current WCM-Q pre-medical students, a quiz session, and several other engaging activities. The event, which is organised by WCM-Q's Office of Student Outreach and Development, also serves to develop partnerships between WCM-Q and local secondary and high schools, stimulate interest in careers in science and medicine among pre-university students, and help enhance college readiness conference is open to students, teachers and school counselors from all over Qatar, across the wider region and beyond. Noha Saleh, director of pre-medical administration, student outreach and educational development, said: 'The Doctors of the Future Conference provides an annual interactive platform where high school students engage with peers from other high schools, current medical students as well as faculty members at WCM-Q, in order to enhance their research skills and understanding of college expectations. We were delighted to welcome so many enthusiastic and highly accomplished students to the conference once again this year.' The second day of the conference featured the final round of the research contest, with first prize going to the team from GEMS Wellington International School Qatar for their poster, titled 'The Effect of Gaming on Promoting Knowledge, Attitude and Awareness of Diabetes'.The competition began with a preliminary round in January 2025 with an initial field of 54 teams. Second place was shared by teams from Doha College and Swiss International School Qatar. Mohamed Siddig Mohyeldin, a student at GEMS Wellington School Qatar and a member of the winning team in the research competition, said: 'The conference was an amazing learning experience. Getting to meet both doctors and medical students helped me to understand what it is really like to study and practice medicine, which has helped me feel more confident about choosing this career path.' Heidi Elkassas, a student at Doha College and a member of one of the second-placed teams in the research competition, said: 'We did a lot of preparation so it was great to go so far in the contest. The best thing about the conference for me was the panel discussions, which were really informative but also very inspiring—there was so much useful advice from different perspectives. One of the big messages I received was to believe in yourself, because if you work hard you can achieve your ambition to become a doctor and make a real difference.' Dr Rachid Bendriss, associate dean for foundation, student outreach and educational development programmes, said:'Our Doctors of the Future Conference continues to offer pre-university students a highly effective way to engage with the worlds of science, medicine, and higher education, while simultaneously helping them to develop skills that will enhance their readiness to apply to college.'
