Latest news with #Zeiger
Medscape
14-05-2025
- Health
- Medscape
Early Food Allergy May Increase Odds of Atopic March
In children with early-onset atopic dermatitis, the presence of food allergy by age 36 months was associated with an increased risk for atopic march, including moderate to severe asthma, allergic rhinitis, and anaphylaxis, by age 11 years. METHODOLOGY: To assess the impact of food allergies on the progression of atopic dermatitis to other atopic disorders, researchers analyzed electronic health records from 10,688 children (57.5% boys) who had atopic dermatitis by 36 months of age. Of these children, 2273 had probable food allergies. The investigators examined the association between baseline child and maternal characteristics and the development of moderate to severe asthma, allergic rhinitis, and anaphylaxis between the ages of 5 years and 11 years. TAKEAWAY: Children with food allergies had a 42% higher risk of developing moderate to severe asthma, a 34% higher risk of developing allergic rhinitis, and a 69% higher risk of developing anaphylaxis between ages 5 years and 11 years than those without food allergies ( P < .001 for all). < .001 for all). Compared with children without food allergies, those with food allergies were more likely to receive systemic corticosteroids (13.9% vs 23.8%) and had a higher prevalence of eosinophilic esophagitis (< 0.01% vs 0.5%; P < .001 for all). < .001 for all). Children with food allergies were more likely to have elevated blood eosinophil levels and had more consultations with allergists and dermatologists. IN PRACTICE: The findings 'strongly support the importance of early-onset food allergy as an additive atopic disorder in promoting the atopic march' in children with atopic dermatitis, the authors wrote. 'Food allergy enhances both present and future atopic conditions, including asthma, allergic rhinitis, anaphylaxis, eosinophilic esophagitis, allergen sensitization, and elevated levels of blood eosinophils.' SOURCE: Robert S. Zeiger, MD, PhD, with Kaiser Permanente Southern California, San Diego, was the corresponding author of the study, which was published online on May 7 in The Journal of Allergy and Clinical Immunology: In Practice . LIMITATIONS: Not all probable food allergy diagnoses were definitively confirmed. Laboratory testing was inconsistent. DISCLOSURES: This study was supported by Sanofi and Regeneron Pharmaceuticals. Some authors were employees of Sanofi, Regeneron, or Aesara. Zeiger had received grant support from ALK-Abelló, AstraZeneca, Blueprint Technologies, Merck, Sanofi, and the National Heart, Lung, and Blood Institute. He also had received consultant fees from AstraZeneca and Merck and warrants from DBV Technologies.
Yahoo
24-04-2025
- General
- Yahoo
Two years ago, Rochester first responders saved Jeff Zeiger's life. He wants to honor their life-saving work
Apr. 24—ROCHESTER — In October 2023, Rochester resident Jeff Zeiger suffered cardiac arrest while strolling along the bike path of Cascade Lake in northwest Rochester. Zeiger was lucky. The vast majority of people die from such cardiac events when they occur outside a hospital setting. If not for a woman who was walking behind him and who began immediately to administer CPR and the work of firefighters whose station was not half a mile away, Zieger would not be with us today. Zeiger's heart was shocked back to life. And so, Zeiger feels grateful. He's not stopped feeling grateful. So much so that Zeiger wants a memorial bench installed near the spot where he almost died as a way of honoring the work of first responders. The work of first responders is taken for granted, he said. "I'm trying to bring visibility and gratitude to the first responders in our city and elsewhere to make people more aware of what they do," Zeiger said. "They run into freaking buildings that are on fire when you and I run the other way." The bench Zeiger has in mind would be located on the south side of Cascade Lake, near the fishing pier. First responders are unsung heroes, he said. He would like them to be a little less unsung. It would join other memorial benches that dot the 2.4-mile loop. Zeiger, a retired university professor, imagines the 5-inch-by-10-inch plaque inscribed with a simple statement of dedication to the work first responders do. The language would be general. It would not specifically mention that they saved Zeiger's life. The focus would be on first responders, not on him. It would cost an estimated $3,200 to purchase and install a memorial bench. So far, $415 has been raised on a GoFundMe site . Zeiger would love a dedication ceremony for the bench to be held on Oct. 28, a date that has special meaning for him. It was the day on which Rochester first responders saved his life. It is also, coincidentally enough, the day when National First Responders Day is celebrated. "Isn't that crazy," Zeiger said.
