Latest news with #glioblastoma
Daily Mail
a day ago
- General
- Daily Mail
TV anchor heartbroken as firefighter husband, 42, dies just years after devastating diagnosis
A Chicago television news anchor is mourning the loss of her firefighter husband after following a grueling and courageous battle with stage 4 brain cancer. Diane Pathieu, who broadcasts for ABC 7, revealed how her spouse Nicholas Adamski passed away last week at the age of 42. Adamski died after attempting to fight the cancer for four years having been diagnosed shortly before Christmas in 2020, after suffering a seizure that left him collapsed and unconscious. Adamski always faced long odds but managed to live years beyond his initial glioblastoma prognosis, refusing to surrender even as the disease ravaged his body. In a raw and emotional tribute posted on Instagram, Pathieu shared a black-and-white photo of her husband. 'My angel, Nicholas 'Nick' Adamski, has gained his wings. He was surrounded by love and peace. Firefighter. Husband. Advocate. Hero. 'Nick faced stage 4 glioblastoma brain cancer with unmatched courage, grace, and an unshakable belief in PMA - Positive Mental Attitude. 'He was a man who served others, uplifted everyone he met, and never stopped smiling - even through the hardest days. Forever in our hearts. I love you for always sweetheart. Keep that PMA. Love hard. Help others. And never, ever give up, and as Nick would say, "peace and veggie grease."' The comment section beneath the post quickly flooded with condolences, words of support from friends, colleagues, and complete strangers, many of whom had never met Nick personally. Before illness struck, Adamski had been a Milwaukee firefighter. He was hailed a hero after he once rushed into a burning building to save an infant, an act of courage for which he received the Medal of Valor - the highest honor a firefighter can earn. His selflessness was legendary among his peers and remained unshaken even after his diagnosis. According to ABC 7, Adamski first realized something was wrong when he suffered a seizure in December 2020, collapsing without warning. 'The only thing I remember is my right leg going up and shaking everything,' Adamski recounted. 'After that, I couldn't tell you anything.' Doctors at Lutheran General Hospital delivered the devastating news that he had stage 4 glioblastoma, the most aggressive and lethal form of brain cancer. Even with aggressive treatment, the prognosis was grim with patients typically given about a year to live. But Adamski refused to let a number define his future. His battle cry became three simple letters: PMA - Positive Mental Attitude. A memorial service was held for Nicholas 'Nick' Adamski on Saturday afternoon Adamski stepped into the public eye and attempted to use his diagnosis as a platform to inspire others. He and his wife Pathieu became vocal advocates for brain cancer awareness. The American Brain Tumor Association (ABTA) paid tribute to Adamski in a statement that echoed the depth of feeling over the loss of Adamski's. 'We are deeply saddened by the passing of Nicholas 'Nick' Adamski, beloved husband of ABC7 Chicago's Diane Pathieu,' the organization wrote. ' A devoted firefighter, fierce advocate, and GBM warrior, Nick faced grade 4 glioblastoma with extraordinary courage, grace, and his signature PMA - Positive Mental Attitude. 'Through every challenge, Nick never stopped smiling. He served others, inspired hope, and uplifted everyone around him. His legacy will live on in the hearts of all who knew him - and in the countless lives he touched.' In his final days, Adamski entered hospice care, surrounded by love and by those he had spent his life protecting. Pathieu announced she would be stepping away from social media to spend his remaining time by his side. ABC 7 Chicago issued its own statement of condolence: 'Nick's life was defined by service, strength, and a deep compassion for others. As a member of the Milwaukee Fire Department, he earned the Medal of Valor for saving an infant from a fire. Not only did Nick fight that vicious disease with bravery, but he also inspired others. 'He became a public voice for hope with his signature message of PMA: Positive Mental Attitude. As Diane says, Nick never judged and never complained. He simply loved.' Those who knew Adamski personally speak of a man who remained kind, selfless, and hopeful even as the disease eroded his physical strength. He never wavered in his resolve to 'love hard, help others, and never, ever give up' - a mantra that Pathieu vowed in her post to carry on.
Reuters
2 days ago
- Business
- Reuters
Gilead's CAR-T cell therapy shows promise in deadly brain cancer
CHICAGO, June 1 (Reuters) - A Gilead Sciences-backed therapy made with a patient's own white blood cells shrank tumors in 62% of patients with recurrent glioblastoma, a rare event for a fatal brain cancer with few treatment options, researchers reported on Sunday. The study, presented at the American Society of Clinical Oncology meeting in Chicago and published in Nature Medicine, is the latest among several efforts testing next-generation chimeric antigen receptor T-cell or CAR-T treatments, a type of immunotherapy in which patients' immune cells are engineered to recognize and kill cancer cells. The work, from researchers at the University of Pennsylvania and Gilead's (GILD.O), opens new tab Kite cell therapy unit, tested a dual CAR-T treatment in an effort to overcome the defenses of glioblastoma, the most common brain tumor in adults. CAR-T therapy is already used to treat blood cancers including leukemia, lymphoma and multiple myeloma, and those treatments typically only take aim at one target on the tumor. But solid tumors such as glioblastoma tend to have multiple subpopulations of tumor cells, suggesting that treatments will need more than one target to succeed, said University of Pennsylvania researcher Dr. Stephen Bagley, who led the study. For the treatment, which is injected directly into spinal fluid, the team selected EGFR, which is found in 50% to 60% of all glioblastoma tumors, and a second target called interleukin-13 receptor alpha 2, found in an estimated 75% of glioblastoma tumors. Typically, advanced glioblastoma patients whose cancers return after initial treatment with surgery, radiation and chemotherapy live six to 10 months. Interim results of just six patients were published in March 2024 in Nature Medicine, opens new tab. The current study now includes 18 patients treated with the experimental therapy after their tumors returned following standard treatment. Of these, only 13 had a measurable tumor at the time the cells were introduced, and of those, eight, or 62%, had their tumors shrink, Bagley said. "That was pretty remarkable to us because historically for recurrent glioblastoma tumors, we usually don't see anything shrink them." Several patients lived 12 months or longer, and in one patient, the disease remained stable for 16 months. But so far, the benefit is largely temporary, with many patients relapsing two to three months later. Most patients experienced fevers and neurotoxicity such as lethargy or confusion for two or three days after the cells are injected, but the side effects were manageable, Bagley said. Cindy Perettie, executive vice president of Gilead's Kite cell therapy unit, said she is encouraged by the 62% response. "What we didn't see that we wanted to in a majority of the patients was persistence," she said. Kite is working to develop a third target that will allow the drug to remain in the brain longer. "We will be putting that construct into the clinic sometime next year," she said. Meanwhile, the team wants to test the therapy in 12 patients with newly diagnosed disease. "We know patients in the frontline setting are going to be healthier," she said, and the hope is to see more persistent results. Demand for the trial has been great. Perettie estimates there are 10 times as many patients seeking enrollment for every open slot, and some doctors are referring patients from as far away as Hawaii. "Today, there's only one approved therapy outside of radiation, so for these patients, this is really exciting to see any kind of response," she said. Kite hopes to expand to three or four centers with its triple-target version of the product. "I think we're on the right track," Bagley said, adding that he believes there will be longer-lasting treatments in the next few years.
Yahoo
2 days ago
- Entertainment
- Yahoo
A Clip Of Joe Biden Comforting Meghan McCain On The View After Dad John's Cancer Diagnosis Is Going Viral Again After She Supported Him
When you buy through links on our articles, Future and its syndication partners may earn a commission. Meghan McCain has never been afraid to speak her mind and criticize public figures (like Meghan Markle) and politicians, like Joe Biden, when she does not agree with them. However, despite disagreeing with the former president on many occasions, she released a statement about his recent cancer diagnosis and put politics to the side. Now, a clip of Biden comforting her in 2017 after her own father's diagnosis is going viral. In the video from a 2017 episode of The View, which you can see below, Meghan McCain spoke about how Biden's late son Beau was diagnosed with the same cancer her father, John, had. So, when the former vice president appeared on the talk show, he comforted her and discussed his history with glioblastoma as well as his friendship with John McCain: As you saw, Biden spoke highly of Meghan's father and how he inspired his son, saying John 'gave Beau courage.' Then, he opened up about how much his son admired the former senator's 'courage.' He also explained the severity of glioblastoma, saying: Beau talked about your dad's courage. Not about illness, but about his courage. And look, there's a lot of things happening. Any of you who have somebody who is diagnosed with glioblastoma, which is about as bad as it gets, there's breakthroughs that are occurring now. The former president talked about different medical breakthroughs regarding this medical condition, as well as the foundation he works with. On top of that, he comforted Meghan by reiterating the close relationship he shared with her father, even when they disagreed: So, there is hope…Her dad is one of my best friends. Her dad goes after me hammer and tongue. We're like two brothers who were somehow raised by different fathers, or something, because of our points of view. Biden then discussed how much he cared for John McCain and vice versa, saying he knew that if something happened, he could count on him to be there. Now, following his own cancer diagnosis, this clip is going viral. It's been years since Meghan McCain left The View, however, her turbulent relationship with the daytime talk show is still discussed frequently. She will also criticize The View's co-hosts when something happens on the show that she disagrees with. That history, as well as her feelings about Biden's politics, have led to mixed reactions to this clip. However, many have remained positive and emotional, considering Biden's current battle with prostate cancer is reminiscent of John McCain's, as @allenanalysis pointed out: This video of President Biden comforting Meghan McCain as she broke down over her father's cancer is resurfacing, and it hits harder now. Now the fight is his. Speedy recovery, Mr. President. Fight like hell. Earlier in May, news broke that Biden had 'an aggressive form of prostate cancer,' per NYT, and it had spread to his bones. Thinking about that and what John McCain went through, this video left many emotional, as they commented: I get choked up every time by Biden's humanity and quite frankly by the deep pain Meghan McCain was feeling. -@DannyHulse3 Hope🫶🏽 -@babesmile As he is now facing this horrible a reminder, Meghan is one of the haters, even still, Pres. Biden comforted her. He is a good man with a heart of gold. And yes, now the fight is his. Let's see if she shows him the same compassion & comfort… -@ely_cat2 This was one of the most touching moments on The View. The way he comforted @MeghanMcCain showed what a truly compassionate man he is. -@popems42 There was also a fair share of comments that called out how Meghan has criticized Biden in the years since this interaction happened. It's worth reiterating that after the former president's diagnosis was made public, John McCain's daughter issued a statement of support. She wished him 'nothing but healing, prayers, light and strength.' She also noted in it that she did not believe this was a time that was 'appropriate for politics.' Now, as we learn more about this tragic diagnosis Joe Biden received as well as where his relationship with Meghan McCain stands, we'll keep you updated.
Yahoo
3 days ago
- Entertainment
- Yahoo
Sheinelle Jones' 'Today 'Colleagues Show Their Support at Her Husband Uche Ojeh's Funeral
Sheinelle Jones' husband, Uche Ojeh, died of glioblastoma, an aggressive form of brain cancer, on Friday, May 23 That day, her Today show colleagues announced his death on behalf of Jones to viewers Jones' colleagues were spotted alongside her at Ojeh's funeral on Friday, May 30 in New York CitySheinelle Jones' Today show colleagues continue to stand by her side following her husband Uche Ojeh's death. Ojeh (full name Uchechukwuka Adenola Ojeh) died of brain cancer on Friday, May 23. He was 45. His funeral was on Friday, May 30, in New York City. Jones' coworkers Savannah Guthrie, Craig Melvin, Al Roker, Jenna Bush Hager and Hoda Kotb attended the service in remembrance of Ojeh. Photos show the emotional group leaving the service, per the New York Post. A teary Melvin was photographed holding a tissue, while Bush Hager, 43, stood beside him, and Kotb, 60, Roker, 70, and his wife, Deborah Roberts, were behind them. Another image showed Guthrie, 53, teary-eyed, descending the church steps. Guthrie announced with "profound sadness" that Jones' husband of 18 years, died after a "courageous battle" with glioblastoma, an aggressive form of brain cancer, on May 23. They share three kids: 15-year-old Kayin and 12-year-old twins Clara and Uche. Guthrie was joined by Today co-hosts Carson Daly, Dylan Dreyer, Roker, Bush Hager and Melvin, 46, as she shared the news and they reflected on how "strong" Jones has been. "Sheinelle has been so strong through all of this, as was Uche," Guthrie said. 'There are no words for the pain we feel for Sheinelle and their three young children. Uche was an incredible person,' Guthrie continued. 'We all loved him. And so we want to take a moment to tell you more about the remarkable man who was Sheinelle's perfect partner in life.' "We just want to say Sheinelle, Kayin, Uche and Clara and the Ojeh family: we are with you, we love you,' she said. 'You are our family and we're just sending all of our love to you right now." Several of Jones' colleagues reiterated Guthrie's sentiments. Daly, a father of four, reflected on the death of his 46-year-old father when he was 5 years old. 'You think so much about these young children, your heart goes out to them,' Daly said. 'So I pray for their family and the kids that they'll have that fortune as well.' Melvin provided insight into his friendship with Ojeh and explained how he was a devoted father. 'One thing he always talked about, he talked about those kids. He loved those kids more than anything else in this world and was just so proud,' Melvin said. 'He was that dad that was on the sidelines of all the soccer games. He was at all the concerts and the recitals. He was that guy." In the wake of the announcement, Jones shared a message on social media on Friday, May 23. "Thank you, for all of your love and support. ❤️" Jones captioned a video of the Today segment. Never miss a story — sign up for to stay up-to-date on the best of what PEOPLE has to offer, from celebrity news to compelling human interest stories. Jones and Ojeh first crossed paths at Northwestern University. Jones met Ojeh when she was a freshman in college, while he was still a high school senior visiting the university, Jones said in an interview for the campus magazine's winter 2024 edition. After dating for eight years, he proposed on the campus of their alma mater in the middle of a rainstorm. The couple tied the knot in 2007. Read the original article on People
Yahoo
3 days ago
- Entertainment
- Yahoo
Sheinelle Jones' 'Today 'Colleagues Show Their Support at Her Husband Uche Ojeh's Funeral
Sheinelle Jones' husband, Uche Ojeh, died of glioblastoma, an aggressive form of brain cancer, on Friday, May 23 That day, her Today show colleagues announced his death on behalf of Jones to viewers Jones' colleagues were spotted alongside her at Ojeh's funeral on Friday, May 30 in New York CitySheinelle Jones' Today show colleagues continue to stand by her side following her husband Uche Ojeh's death. Ojeh (full name Uchechukwuka Adenola Ojeh) died of brain cancer on Friday, May 23. He was 45. His funeral was on Friday, May 30, in New York City. Jones' coworkers Savannah Guthrie, Craig Melvin, Al Roker, Jenna Bush Hager and Hoda Kotb attended the service in remembrance of Ojeh. Photos show the emotional group leaving the service, per the New York Post. A teary Melvin was photographed holding a tissue, while Bush Hager, 43, stood beside him, and Kotb, 60, Roker, 70, and his wife, Deborah Roberts, were behind them. Another image showed Guthrie, 53, teary-eyed, descending the church steps. Guthrie announced with "profound sadness" that Jones' husband of 18 years, died after a "courageous battle" with glioblastoma, an aggressive form of brain cancer, on May 23. They share three kids: 15-year-old Kayin and 12-year-old twins Clara and Uche. Guthrie was joined by Today co-hosts Carson Daly, Dylan Dreyer, Roker, Bush Hager and Melvin, 46, as she shared the news and they reflected on how "strong" Jones has been. "Sheinelle has been so strong through all of this, as was Uche," Guthrie said. 'There are no words for the pain we feel for Sheinelle and their three young children. Uche was an incredible person,' Guthrie continued. 'We all loved him. And so we want to take a moment to tell you more about the remarkable man who was Sheinelle's perfect partner in life.' "We just want to say Sheinelle, Kayin, Uche and Clara and the Ojeh family: we are with you, we love you,' she said. 'You are our family and we're just sending all of our love to you right now." Several of Jones' colleagues reiterated Guthrie's sentiments. Daly, a father of four, reflected on the death of his 46-year-old father when he was 5 years old. 'You think so much about these young children, your heart goes out to them,' Daly said. 'So I pray for their family and the kids that they'll have that fortune as well.' Melvin provided insight into his friendship with Ojeh and explained how he was a devoted father. 'One thing he always talked about, he talked about those kids. He loved those kids more than anything else in this world and was just so proud,' Melvin said. 'He was that dad that was on the sidelines of all the soccer games. He was at all the concerts and the recitals. He was that guy." In the wake of the announcement, Jones shared a message on social media on Friday, May 23. "Thank you, for all of your love and support. ❤️" Jones captioned a video of the Today segment. Never miss a story — sign up for to stay up-to-date on the best of what PEOPLE has to offer, from celebrity news to compelling human interest stories. Jones and Ojeh first crossed paths at Northwestern University. Jones met Ojeh when she was a freshman in college, while he was still a high school senior visiting the university, Jones said in an interview for the campus magazine's winter 2024 edition. After dating for eight years, he proposed on the campus of their alma mater in the middle of a rainstorm. The couple tied the knot in 2007. Read the original article on People
