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"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point
"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point

Yahoo

time3 days ago

  • Entertainment
  • Yahoo

"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point

If you have not ridden the rollercoaster known as perimenopause, congrats. Ditto if you're one of the lucky ones who can say it was "not that bad." But for many women, the years leading up to menopause can bring with them hot flashes, insomnia, vertigo, vaginal dryness, joint pain, and a host of other "fun" surprises. It's like a second puberty, but there's no Judy Blume book for this. So when I, a frequent flyer on Hot Flash Airlines, came across Melani (@justbeingmelani) on TikTok, it was like a breath of fresh air. Melani is the founder of the "We Do Not Care Club," a group for women in perimenopause and menopause. In the comments of her daily videos, women share things that we simply do not care about today. Then, the next day, Melani reads them back to the club, and commenters add new submissions. Here are some of my personal favorite "We Do Not Care Club" submissions that made me laugh and nod my head "yes" so hard I got a neck ache: 1."I don't care that I have a California king and I sleep on one half and the other half is a two-week pile of clothes out of the dryer." —sam_i_am_1968 2."I don't care what my family eats for dinner NO MORE! Eat Funyuns and jellybeans, WDNC." —khershalynn 3."WDNC what we look like from the back. That is not our business." —sarahh5510 4."WDNC Club....I finally found my people!!!!! WDNC if anyone can tell if we don't have a bra on under the hoodie. The hoodie is an automatic exemption from a bra." —macarone33 5."We don't care about learning new music. The '90s was the best era anyway!!" —ashan1976 6."I do not care that my hair has been in a ponytail since 2001." —amysims50 7."We don't care that we want to be home all day on our days off! Everything I like is at home. I paid for it, Imma stay in it!" —vhardy.7 8."We do not care what healthy salad, vegan, vegetarian, gluten-free, lactose-free rubbish our co-workers are having for lunch. Just let me eat my lasagne in peace!" —lararandle1 Related: "I Know You Aren't Trying To Hurt Me." Doctors, Nurses, And First Responders Are Revealing The Most "Haunting" Last Words They've Heard From A Patient 9."And I don't care about the perfect kitchen/bathroom/bedroom beige Pinterest aesthetic. I'm too old and tired. WDNC club." —itsjusterind 10."We don't care about those lights on the dashboard. If the car is moving, it's fine." —lemonzest83 11."We do not care if our shoes are cute. Comfortable shoes only." —rme80 12."I do not care how long it takes for me to put my wallet back into my purse after I pay for my groceries. Your turn starts when I am finished. Don't rush me." —luckyredfriday 13."WDNC about washing instructions. If it can't survive a cold wash and a dry cycle, then it wasn't for me anyway." —shannihilation 14."I do not care if people think my legs are too fat for shorts. It's hot. You're lucky I'm wearing anything." — Related: 27 Grown-Ass Adults Who Threw Such Unbelievable Temper Tantrums, Even The Brattiest Toddler Couldn't Compete 15."WDNC to go to another work event. My teambuilding skills expired and will not be renewed." —bethklongpayabal 16."We do not care if the AC is on 60. Don't touch that fan. If you're cold, get an extra blanket. I'm good." —mizzterminator 17."I do not care if I fart when I walk. It is out of my control." —heidimark1 18."WDNC about folding our fitted sheets. I'm rolling them up in a ball and throwing them in the dresser. They will straighten themselves out!!!" —sprouting_with_ivy 19."We do not care to wear hard pants ever again." —mylittlegardenplot 20."We do not care if we said we would go. We changed our minds as soon as we got home." — 21."I do not care if my resting b—— face offends anyone. It's my face, it's not going to change right now." —lorib431 22."We do not care if we have pet hair all over our clothes. Our pets are the only people we like." —mookiepookie23 23."WDNC. I'm gonna start eating the rotisserie chicken as soon as I get in the car." —yourmom77777777777 24."We do not care if it says 'Not Dishwasher Safe.' It's about to learn some hard lessons in this house 😆." —theathletesocialcoach 25."Logging in from the Paris, France chapter of the WDNC club. We do not care if carbs and butter are 'bad' for us. Give us the damn croissant and nobody gets hurt." —giadecadenet 26."WDNC if the house is clean when you come over, also don't come over." —bratcat178 27."WDNC if we forget the name of something. We will make a new word for it, and you will have to understand what I meant." —noonespecial0515 28."We do not care that we no longer keep a poker face at work. My eyebrow said what it said." —tlen1985 29."We do not care if a side part or a middle part is the hot trend. We style our hair whatever way the wind blows." —caryzel 30."We do not care if we repeat the same story twice. If it was good once, it'll be better the second time." —dorkapottamus finally, "I do not care that this club is for perimenopause/menopause women and I'm in my 20s, I relate to everything 🤣❤️." —imjustdolly_ Follow Melani on TikTok to join the club, and let us know what you do not care about today in the comments! Also in Internet Finds: 51 Wildly Fascinating Photos Of Disorders, Injuries, And Variations In The Human Body That I Cannot Stop Staring At Also in Internet Finds: 23 People Who Tried Their Best, But Crapped The Bed So Bad Also in Internet Finds: 19 Things Society Glorifies That Are Actually Straight-Up Terrible, And We Need To Stop Pretending Otherwise

"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point
"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point

Yahoo

time3 days ago

  • Entertainment
  • Yahoo

"We Simply Do Not Care Anymore": Women Over 40 Are Sharing Things They're Fed Up With At This Point

If you have not ridden the rollercoaster known as perimenopause, congrats. Ditto if you're one of the lucky ones who can say it was "not that bad." But for many women, the years leading up to menopause can bring with them hot flashes, insomnia, vertigo, vaginal dryness, joint pain, and a host of other "fun" surprises. It's like a second puberty, but there's no Judy Blume book for this. So when I, a frequent flyer on Hot Flash Airlines, came across Melani (@justbeingmelani) on TikTok, it was like a breath of fresh air. Melani is the founder of the "We Do Not Care Club," a group for women in perimenopause and menopause. In the comments of her daily videos, women share things that we simply do not care about today. Then, the next day, Melani reads them back to the club, and commenters add new submissions. Here are some of my personal favorite "We Do Not Care Club" submissions that made me laugh and nod my head "yes" so hard I got a neck ache: 1."I don't care that I have a California king and I sleep on one half and the other half is a two-week pile of clothes out of the dryer." —sam_i_am_1968 2."I don't care what my family eats for dinner NO MORE! Eat Funyuns and jellybeans, WDNC." —khershalynn 3."WDNC what we look like from the back. That is not our business." —sarahh5510 4."WDNC Club....I finally found my people!!!!! WDNC if anyone can tell if we don't have a bra on under the hoodie. The hoodie is an automatic exemption from a bra." —macarone33 5."We don't care about learning new music. The '90s was the best era anyway!!" —ashan1976 6."I do not care that my hair has been in a ponytail since 2001." —amysims50 7."We don't care that we want to be home all day on our days off! Everything I like is at home. I paid for it, Imma stay in it!" —vhardy.7 8."We do not care what healthy salad, vegan, vegetarian, gluten-free, lactose-free rubbish our co-workers are having for lunch. Just let me eat my lasagne in peace!" —lararandle1 Related: "I Know You Aren't Trying To Hurt Me." Doctors, Nurses, And First Responders Are Revealing The Most "Haunting" Last Words They've Heard From A Patient 9."And I don't care about the perfect kitchen/bathroom/bedroom beige Pinterest aesthetic. I'm too old and tired. WDNC club." —itsjusterind 10."We don't care about those lights on the dashboard. If the car is moving, it's fine." —lemonzest83 11."We do not care if our shoes are cute. Comfortable shoes only." —rme80 12."I do not care how long it takes for me to put my wallet back into my purse after I pay for my groceries. Your turn starts when I am finished. Don't rush me." —luckyredfriday 13."WDNC about washing instructions. If it can't survive a cold wash and a dry cycle, then it wasn't for me anyway." —shannihilation 14."I do not care if people think my legs are too fat for shorts. It's hot. You're lucky I'm wearing anything." — Related: 27 Grown-Ass Adults Who Threw Such Unbelievable Temper Tantrums, Even The Brattiest Toddler Couldn't Compete 15."WDNC to go to another work event. My teambuilding skills expired and will not be renewed." —bethklongpayabal 16."We do not care if the AC is on 60. Don't touch that fan. If you're cold, get an extra blanket. I'm good." —mizzterminator 17."I do not care if I fart when I walk. It is out of my control." —heidimark1 18."WDNC about folding our fitted sheets. I'm rolling them up in a ball and throwing them in the dresser. They will straighten themselves out!!!" —sprouting_with_ivy 19."We do not care to wear hard pants ever again." —mylittlegardenplot 20."We do not care if we said we would go. We changed our minds as soon as we got home." — 21."I do not care if my resting b—— face offends anyone. It's my face, it's not going to change right now." —lorib431 22."We do not care if we have pet hair all over our clothes. Our pets are the only people we like." —mookiepookie23 23."WDNC. I'm gonna start eating the rotisserie chicken as soon as I get in the car." —yourmom77777777777 24."We do not care if it says 'Not Dishwasher Safe.' It's about to learn some hard lessons in this house 😆." —theathletesocialcoach 25."Logging in from the Paris, France chapter of the WDNC club. We do not care if carbs and butter are 'bad' for us. Give us the damn croissant and nobody gets hurt." —giadecadenet 26."WDNC if the house is clean when you come over, also don't come over." —bratcat178 27."WDNC if we forget the name of something. We will make a new word for it, and you will have to understand what I meant." —noonespecial0515 28."We do not care that we no longer keep a poker face at work. My eyebrow said what it said." —tlen1985 29."We do not care if a side part or a middle part is the hot trend. We style our hair whatever way the wind blows." —caryzel 30."We do not care if we repeat the same story twice. If it was good once, it'll be better the second time." —dorkapottamus finally, "I do not care that this club is for perimenopause/menopause women and I'm in my 20s, I relate to everything 🤣❤️." —imjustdolly_ Follow Melani on TikTok to join the club, and let us know what you do not care about today in the comments! Also in Internet Finds: 51 Wildly Fascinating Photos Of Disorders, Injuries, And Variations In The Human Body That I Cannot Stop Staring At Also in Internet Finds: 23 People Who Tried Their Best, But Crapped The Bed So Bad Also in Internet Finds: 19 Things Society Glorifies That Are Actually Straight-Up Terrible, And We Need To Stop Pretending Otherwise

Hot Flashes in Prostate Cancer Market Expected to Strengthen Through 2032 with Growing Awareness and Novel Interventions
Hot Flashes in Prostate Cancer Market Expected to Strengthen Through 2032 with Growing Awareness and Novel Interventions

Globe and Mail

time14-05-2025

  • Health
  • Globe and Mail

Hot Flashes in Prostate Cancer Market Expected to Strengthen Through 2032 with Growing Awareness and Novel Interventions

The hot flashes in prostate cancer market is poised for significant growth through 2032, driven by increasing awareness, improved diagnosis, and the development of more effective interventions from companies such as, Foundation Medicine, Bayer, Ipsen, Exelixis, AstraZeneca, and Synact Pharma, among others, addressing this debilitating side effect of androgen deprivation therapy (ADT). DelveInsight's " Hot Flashes in Prostate Cancer Market Insights, Epidemiology and Market Forecast-2032" report provides an in-depth understanding of hot flashes in prostate cancer patients, historical and forecasted epidemiology trends, as well as market dynamics across the 7MM, which include, the US, EU4 (Germany, France, Italy, and Spain), the UK, and Japan. The report covers current treatment practices, emerging therapies, market share of individual treatments, and hot flashes in the prostate cancer market size, offering valuable insights for healthcare stakeholders and pharmaceutical developers. The US currently represents the largest share of the hot flashes in the prostate cancer market, with substantial growth projected through 2032. This growth trajectory is supported by favorable reimbursement policies, increased awareness among healthcare providers, and the rapid adoption of novel interventions targeting this specific symptom. The EU4 countries and the United Kingdom collectively constitute the second-largest market segment, while Japan shows promising growth potential as awareness of this condition increases in the Asia-Pacific region. Download the Hot Flashes in Prostate Cancer Market Forecast Report to understand which factors are driving the Hot Flashes in Prostate Cancer market @ Hot Flashes in Prostate Cancer Market Trends. Hot flashes, commonly associated with menopause in women, have emerged as a significant phenomenon in men undergoing prostate cancer treatment, particularly those receiving androgen deprivation therapy. ADT works by reducing testosterone levels, which often triggers sudden and intense waves of heat accompanied by perspiration and flushed skin. This treatment-induced side effect affects a substantial proportion of prostate cancer patients, with the prevalence expected to increase as ADT remains a cornerstone therapy for hormone-sensitive prostate cancer management. Traditionally seen as a female experience, these vasomotor symptoms now represent a significant unmet need in male oncology care, affecting treatment adherence and quality of life. DelveInsight's analysis shows that between 30% and 80% of men with prostate cancer, especially those undergoing androgen deprivation therapy (ADT), experience hot flashes. The onset of hot flashes typically occurs within weeks of starting hormone therapy, and the symptoms can persist for months or even years. Furthermore, the prevalence is higher in older men, with a mean age of onset around 70, and the median number of hot flashes reported is about three per day. While most men eventually experience remission of symptoms, a significant proportion continue to have hot flashes long-term, which can negatively affect quality of life. Discover evolving trends in the Hot Flashes in Prostate Cancer patient pool forecasts @ Hot Flashes in Prostate Cancer Epidemiological Analysis. The current landscape of hot flash management in prostate cancer encompasses various approaches, including pharmacological interventions such as hormone replacement therapies, antidepressants, anticonvulsants, and non-pharmacological strategies, including lifestyle modifications and wearable cooling technologies. The market has witnessed an increased focus on addressing this side effect, prompting innovative research into targeted therapies that specifically address the neurohormonal pathways involved in hot flash generation without compromising the efficacy of anticancer treatments. This represents a significant shift from historical approaches that often considered hot flashes an inevitable and acceptable consequence of life-extending prostate cancer therapies. Recent developments have significantly shaped the evolving landscape of hot flashes management in prostate cancer. Several effective treatments, such as Oxybutynin, an oral medication traditionally used for overactive bladder, have shown strong results in reducing both the frequency and severity of hot flashes in men on ADT, as demonstrated in a 2024 phase II trial. Non-hormonal agents like venlafaxine have also shown efficacy in smaller studies. New hormone therapies, such as ORGOVYX (relugolix), the first oral GnRH antagonist approved by the FDA, offer convenient alternatives to injectable treatments and may help manage hot flashes as part of overall ADT regimens. Additionally, a ready-to-use 3-month leuprolide depot formulation is nearing FDA approval, promising more flexible treatment options for advanced prostate cancer. Research is ongoing into novel agents targeting the neurokinin pathway, such as fezolinetant and elinzanetant, which have shown promise in reducing hot flashes in cancer patients, although data in prostate cancer specifically are still emerging. Discover evolving trends in the Hot Flashes in Prostate Cancer treatment landscape @ Hot Flashes in Prostate Cancer Recent Developments. Looking ahead, the hot flashes in prostate cancer market is expected to witness substantial growth driven by several factors, including the rising incidence of prostate cancer, increased adoption of ADT as a standard treatment approach, growing awareness among healthcare providers about the impact of hot flashes on treatment adherence and patient quality of life, and the development of novel targeted interventions. Companies such as Foundation Medicine, Bayer (ETR: BAYN), Ipsen (EPA: IPN), Exelixis (NASDAQ: EXEL), AstraZeneca (NASDAQ: AZN), and Synact Pharma (STO: SYNACT), among others, are actively involved in this space, reflecting a growing focus on both cancer control and symptom management. Additionally, the integration of digital health solutions and wearable technologies for symptom monitoring and management presents exciting opportunities for market expansion. However, challenges remain, including the need for standardized assessment tools for hot flash severity in men, limited awareness among some healthcare providers, and reimbursement barriers for symptom-focused treatments. DelveInsight's analysis emphasizes that companies developing therapies for hot flashes in prostate cancer patients should focus on interventions that not only reduce symptom frequency and severity but also maintain the therapeutic efficacy of anticancer treatments. The increasing recognition of hot flashes as a legitimate treatment target rather than merely an acceptable side effect represents a paradigm shift in prostate cancer management, opening new avenues for therapeutic development and market growth. Table of Contents 1. Key Insights 2. Executive Summary of Hot Flashes in Prostate Cancer 3. Hot Flashes in Prostate Cancer Competitive Intelligence 4. Hot Flashes in Prostate Cancer: Market Overview at a Glance 5. Hot Flashes in Prostate Cancer: Disease Background and Overview 6. Patient Journey 7. Hot Flashes in Prostate Cancer Epidemiology and Patient Population 8. Treatment Algorithm, Current Treatment, and Medical Practices 9. Hot Flashes in Prostate Cancer Unmet Needs 10. Key Endpoints of Hot Flashes in Prostate Cancer Treatment 11. Hot Flashes in Prostate Cancer Marketed Products 12. Hot Flashes in Prostate Cancer Emerging Therapies 13. Hot Flashes in Prostate Cancer: Seven Major Market Analysis 14. Attribute analysis 15. 7MM: Market Outlook 16. Access and Reimbursement Overview of Hot Flashes in Prostate Cancer 17. KOL Views 18. Hot Flashes in Prostate Cancer Market Drivers 19. Hot Flashes in Prostate Cancer Market Barriers 20. Appendix 21. DelveInsight Capabilities 22. Disclaimer 23. About DelveInsight About DelveInsight DelveInsight is a leading market research and consulting firm specializing in disease-specific insights and therapeutic market analysis. Their reports integrate real-world data, clinical trial findings, and expert interviews to deliver comprehensive industry intelligence. Media Contact Company Name: DelveInsight Business Research LLP Contact Person: Arpit Anand Email: Send Email Phone: +14699457679 Address: 304 S. Jones Blvd #2432 City: Las Vegas State: Nevada Country: United States Website:

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