Latest news with #mastectomy
Yahoo
5 days ago
- Health
- Yahoo
Thousands of cancer cases could be prevented with more breast removal surgeries
Thousands of breast cancer cases could potentially be prevented if more women were offered 'risk reducing' breast removal surgery, a study suggests. Breast removal surgery, also known as a mastectomy, is offered to treat breast cancer in some women. It can also be offered to women who are deemed to be high risk of the disease to prevent them from getting it in the first place. A study has found that if more women were given preventative mastectomies, then about 6,500 cases of breast cancer could be prevented each year. Risk-reducing mastectomies (RRM) are currently only offered to women with the BRCA1, BRCA2, PALB2 genes, experts said. But the new analysis suggests that some women with other genes linked to a higher risk of breast cancer – including ATM, CHEK2, RAD51C, RAD51D – who may also be at higher risk due to a number of other factors may benefit from RRM if they are assessed as having a high risk of disease. These other factors can include a family history of breast cancer, the number of children they have had, whether or not they breast fed and mammogram density. Women in the UK have an 11% chance of developing breast cancer across their lifetime. Medics can calculate a woman's risk of breast cancer using tools which combine the effect of various risk factors. This is your breast check reminder! Learn the signs and symptoms of breast — Breast Cancer Now (@BreastCancerNow) May 6, 2025 Researchers from Queen Mary University of London and the London School of Hygiene and Tropical Medicine (LSHTM) found that if health officials could identify all women aged 30 to 55 who have a 35% or higher risk of breast cancer, and they all went on to have RRM, then an estimated 6,538 breast cancer cases could be prevented in the UK each year. This is the equivalent of around 11% of the 59,000 women in the UK who are diagnosed with breast cancer each year. The academics point out that women who have one of the other genes linked to breast cancer, who may be at high risk of disease, could potentially be found by a mechanism called 'cascade testing' – where genetic tests are offered to family members of women who have been found to have these different genes linked to breast cancer. The economic evaluation study, published in the journal JAMA Oncology, concludes: 'Undergoing RRM appears cost-effective for women at 30-55 years with a lifetime BC-risk 35% (or more). 'The results could have significant clinical implications to expand access to RRM beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers.' Corresponding author on the paper, Professor Ranjit Manchanda, professor of gynaecological oncology at Queen Mary and consultant gynaecological oncologist, said: 'We for the first time define the risk at which we should offer RRM. 'Our results could have significant clinical implications to expand access to mastectomy beyond those patients with known genetic susceptibility in high penetrance genes- BRCA1/ BRCA2/ PALB2 – who are traditionally offered this. 'This could potentially prevent can potentially prevent (around) 6500 breast cancer cases annually in UK women. 'We recommend that more research is carried out to evaluate the acceptability, uptake, and long-term outcomes of RRM among this group'. Dr Rosa Legood, associate professor in health economics at LSHTM, added: 'Undergoing RRM is cost-effective for women (aged) 30 to 55-years with a lifetime breast cancer risk of 35% or more. 'These results can support additional management options for personalised breast cancer risk prediction enabling more women at increased risk to access prevention.' Women deemed to be at high risk of breast cancer can also be offered regular screening and medication. Louise Grimsdell, Breast Cancer Now senior clinical nurse specialist, said: 'While this modelling provides valuable insights into the cost-effectiveness of risk-reducing mastectomy for women with a high risk of developing breast cancer, each individual must be offered all risk-management options that are suitable for them. 'Choosing to have risk-reducing surgery is a complex and deeply personal decision that comes with emotional and physical implications. 'So, it's vital women can consider all their options, including screening and risk-reducing medications, and are supported by their clinician to make an informed decision that's right for them. 'It's also crucial that the unacceptably long waits that far too many women who chose risk-reducing surgery are facing are urgently tackled.'
The Independent
5 days ago
- Health
- The Independent
‘Risk-reducing' surgery could prevent thousands of breast cancer cases
Thousands of breast cancer cases could be averted each year if more women were offered 'risk-reducing' breast removal surgery, a new study suggests. This intervention, known as a mastectomy, is currently used to treat existing cancer or offered to those with a high genetic predisposition, specifically women carrying the BRCA1, BRCA2, or PALB2 genes. The analysis indicates that approximately 6,500 cases of breast cancer could be prevented annually if preventative mastectomies were more widely adopted. Crucially, the research proposes expanding eligibility beyond the currently recognised genetic markers. Women with other genes linked to increased risk, such as ATM, CHEK2, RAD51C, and RAD51D, may also benefit. Furthermore, the study highlights that a combination of other factors, including a family history of breast cancer, parity (number of children), breastfeeding history, and mammogram density, should be considered in assessing a woman's overall high risk for the disease, potentially making them candidates for risk-reducing mastectomies. Women in the UK have an 11 per cent chance of developing breast cancer across their lifetime. Medics can calculate a woman's risk of breast cancer using tools which combine the effect of various risk factors. Researchers from Queen Mary University of London and the London School of Hygiene and Tropical Medicine (LSHTM) found that if health officials could identify all women aged 30 to 55 who have a 35 per cent or higher risk of breast cancer, and they all went on to have RRM, then an estimated 6,538 breast cancer cases could be prevented in the UK each year. This is the equivalent of around 11 per cent of the 59,000 women in the UK who are diagnosed with breast cancer each year. The academics point out that women who have one of the other genes linked to breast cancer, who may be at high risk of disease, could potentially be found by a mechanism called 'cascade testing' – where genetic tests are offered to family members of women who have been found to have these different genes linked to breast cancer. The economic evaluation study, published in the journal JAMA Oncology, concludes: 'Undergoing RRM appears cost-effective for women at 30-55 years with a lifetime BC-risk 35 per cent (or more). 'The results could have significant clinical implications to expand access to RRM beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers.' Corresponding author on the paper, Professor Ranjit Manchanda, professor of gynaecological oncology at Queen Mary and consultant gynaecological oncologist, said: 'We for the first time define the risk at which we should offer RRM. 'Our results could have significant clinical implications to expand access to mastectomy beyond those patients with known genetic susceptibility in high penetrance genes- BRCA1/ BRCA2/ PALB2 – who are traditionally offered this. 'This could potentially prevent can potentially prevent (around) 6500 breast cancer cases annually in UK women. 'We recommend that more research is carried out to evaluate the acceptability, uptake, and long-term outcomes of RRM among this group'. Dr Rosa Legood, associate professor in health economics at LSHTM, added: 'Undergoing RRM is cost-effective for women (aged) 30 to 55-years with a lifetime breast cancer risk of 35 per cent or more. 'These results can support additional management options for personalised breast cancer risk prediction enabling more women at increased risk to access prevention.' Women deemed to be at high risk of breast cancer can also be offered regular screening and medication. Louise Grimsdell, Breast Cancer Now senior clinical nurse specialist, said: 'While this modelling provides valuable insights into the cost-effectiveness of risk-reducing mastectomy for women with a high risk of developing breast cancer, each individual must be offered all risk-management options that are suitable for them. 'Choosing to have risk-reducing surgery is a complex and deeply personal decision that comes with emotional and physical implications. 'So, it's vital women can consider all their options, including screening and risk-reducing medications, and are supported by their clinician to make an informed decision that's right for them. 'It's also crucial that the unacceptably long waits that far too many women who chose risk-reducing surgery are facing are urgently tackled.'
Telegraph
5 days ago
- Health
- Telegraph
Preventative mastectomies could cut thousands of breast cancer cases
Preventative mastectomies could cut thousands of breast cancer cases, a study has suggested. Breast removal surgery, also known as a mastectomy, is offered to treat breast cancer in some women and can also be recommended to women deemed to be at high risk of the disease as a preventative measure. A study found that if more women were given preventative mastectomies, then some 6,500 breast cancer cases could be cut each year. Risk-reducing mastectomies (RRM) are currently only offered to women with the BRCA1, BRCA2, PALB2 genes, which are linked to a higher risk of breast cancer, experts said. But the analysis has suggested that some women with other genes, including ATM, CHEK2, RAD51C, RAD51D, who may also be at risk because of a number of other factors, may benefit from RRM if assessed as having a higher risk of disease. Such other factors can include a family history of breast cancer, the number of children they have had, whether they have breastfed and mammogram density. Women in the UK have an 11 per cent chance of developing breast cancer across their lifetime. Medics can calculate a woman's risk of breast cancer using tools that combine the effects of various risk factors. 'Significant clinical implications' Researchers from Queen Mary University of London and the London School of Hygiene and Tropical Medicine (LSHTM) found that if health officials could identify all women aged 30 to 55 with a 35 per cent or higher risk of breast cancer and they all went on to have RRM, then an estimated 6,538 cases could be prevented in the UK each year. This is equivalent to around 11 per cent of the 59,000 women in the UK who are diagnosed with breast cancer each year. The academics pointed out that women with one of the other genes linked to breast cancer, who may be at high risk of disease, could potentially be found by a mechanism called 'cascade testing', where genetic tests are offered to family members of women found to have the different genes linked to the disease. The economic evaluation study, which was published in the JAMA Oncology journal, said: 'Undergoing RRM appears cost-effective for women at 30-55 years with a lifetime BC-risk 35 per cent (or more). 'The results could have significant clinical implications to expand access to RRM beyond BRCA1/BRCA2/PALB2 pathogenic variant carriers.' Prof Ranjit Manchanda, one of the paper's authors and a gynaecological oncology professor at Queen Mary University of London, said: 'We, for the first time, define the risk at which we should offer RRM. He added: 'This could potentially prevent [around] 6,500 breast cancer cases annually in UK women. 'We recommend that more research is carried out to evaluate the acceptability, uptake and long-term outcomes of RRM among this group.' Women deemed to be at high risk of breast cancer can also be offered regular screening and medication. Louise Grimsdell, a senior clinical nurse specialist at Breast Cancer Now, said: 'Choosing to have risk-reducing surgery is a complex and deeply personal decision that comes with emotional and physical implications. 'So it's vital women can consider all their options, including screening and risk-reducing medications, and are supported by their clinician to make an informed decision that's right for them.'
Daily Mail
6 days ago
- Entertainment
- Daily Mail
Jessie J reveals huge life change amid breast cancer battle - four weeks after undergoing a mastectomy
Jessie J has revealed that she's sold her beloved Los Angeles home where she lived for over a decade amid her battle with breast cancer. The singer, 37, took to her Instagram on Thursday with a clip of her enjoying one final canyon hike near the property last month, shortly before she returned to the UK for a mastectomy. Jessie is currently in the early stages of recovery following the operation, after revealing the cancer had luckily been caught by doctors 'early'. Sharing the news of her move, she captioned the clip of her jogging with pals: 'June 1st, I flew to LA for just under 48 hours'. 'This quick trip was for a little work but also to say goodbye to my LA house (that had just sold) which was my home for just over a decade'. She continued: 'This hike was my and will always be one of my favourite places in studio city. So grateful I got to have so many happy years in LA, and to visit quickly before my surgery and see some of my favourite people and make memories like this. Jessie relocated to the US in 2014 after claiming she was fed up with gossip about her sex life and said she was 'taken seriously as a singer' across the pond. She shared a glimpse of the swanky mansion, which fans claimed looked like a 'luxury hotel lobby' during the One World viral concert amid the pandemic in 2020. Dressed in a brown striped jumper and gold hooped earrings, Jessie appeared to be sitting on the floor of her living room. Behind her she gave a glimpse of the expansive room, with dazzling spotlights, chic furniture, floor-to-ceiling mirrors and plenty of light. Taking to Twitter, fans couldn't help but remark on her nice home, with one even commenting that it looks like a hotel lobby. 'Damnnn Jessie J just went #PitchPerfect on everyone. Her house also looks like a Marriott lobby' commented one person. While another penned: 'I admire Jessie J. She's like, look at this amazing house. Why even bother to pretend. I earned this.' A third gushed of her abode: 'if it is jessie j's house im looking at it now, it is so damn big holy s**t.' She captioned the clip of her jogging with pals: 'June 1st, I flew to LA for just under 48 hours' Last week Jessie detailed her progress and admitted she was already seeing signs of improvement. Taking to Instagram wrote: 'It will be 4 weeks since my breast cancer surgery on Saturday. I am feeling good. Some days are harder than others. 'My movement is good, still very sore but I am getting more like myself everyday. Mentally it's all catching up with me. So giving myself a little space to feel it all.' The singer revealed she was being tended to by her immediate family while two-year old son Sky visited relatives in Denmark with his father, basketball player Chanan Colman. She added: 'Sky has gone away for 2 weeks with his Dad to his Danish fam, but also so I can rest and do physio. (And re organise the whole house with my Mum and my sister as my body). My adhd and ocd still going strong. 'I'm not allowed to pick Sky up for a few months and that has been a difficult adjustment, I just want to hold him like this and spin around. But in the bigger picture it's a small sacrifice to have my health and to still be here. 'The day will come I can lift him up for a cuddle. I can't wait for that day. That day is what gets me through these days. These days are weird. 'I love being your Mum Sky. I miss my boys.' Taking to Twitter, fans couldn't help but remark on her nice home, with one even commenting that it looks like a hotel lobby 'Jessie J's home is gorgeous and I'm now very jealous' tweeted a fourth. Jessie accompanied the post with a series of affectionate black-and-white photos in which she cradles her young son while working in the studio. The singer previously admitted she went into 'survival mode' upon learning of her diagnosis, but is now letting herself feel angry and sad in equal measure. Sharing an Instagram post in June, she wrote: Jessie wrote: '2 weeks post surgery. Had my drain out 2 nights ago. She said breathe in and take a hard breathe out. She whipped that thang out so quick. Woii oii. Weirdest feeling. But so nice to have it out after 12 days. 'Now it's just me and my wonky boobs trying to figure out how to dress until I match them up. The left one is looking at me like "you ok babe?"'. She continued: 'Also my experience was when I was diagnosed I went into survival mode. 'There was so much going on with appointments and in my mind esp with a toddler I had just moved and was about to start this campaign after 8 years away. Mad. 'I didn't really have a lot of time to process what was happening or what was going to happen. So I'm currently experiencing some delayed sadness and frustration by having time to process what IS happening. 'A little disappointed in myself I didn't say goodbye to my old boob enough. Sounds silly but that's where I'm at. Again that's my journey. I'm sure others feel different. 'But for me I didn't think beyond the surgery. I was just being strong. Well now I'm here and letting myself be angry and sad and all the things. Just for a few days. 'Then I will sew some padding in a bra to even them out order some t-shirts and crack tf on'. Breast cancer is one of the most common cancers in the world and affects more than two MILLION women a year Breast cancer is one of the most common cancers in the world. Each year in the UK there are more than 55,000 new cases, and the disease claims the lives of 11,500 women. In the US, it strikes 266,000 each year and kills 40,000. But what causes it and how can it be treated? What is breast cancer? It comes from a cancerous cell which develops in the lining of a duct or lobule in one of the breasts. When the breast cancer has spread into surrounding tissue it is called 'invasive'. Some people are diagnosed with 'carcinoma in situ', where no cancer cells have grown beyond the duct or lobule. Most cases develop in those over the age of 50 but younger women are sometimes affected. Breast cancer can develop in men, though this is rare. Staging indicates how big the cancer is and whether it has spread. Stage 1 is the earliest stage and stage 4 means the cancer has spread to another part of the body. The cancerous cells are graded from low, which means a slow growth, to high, which is fast-growing. High-grade cancers are more likely to come back after they have first been treated. What causes breast cancer? A cancerous tumour starts from one abnormal cell. The exact reason why a cell becomes cancerous is unclear. It is thought that something damages or alters certain genes in the cell. This makes the cell abnormal and multiply 'out of control'. Although breast cancer can develop for no apparent reason, there are some risk factors that can increase the chance, such as genetics. What are the symptoms of breast cancer? The usual first symptom is a painless lump in the breast, although most are not cancerous and are fluid filled cysts, which are benign. The first place that breast cancer usually spreads to is the lymph nodes in the armpit. If this occurs you will develop a swelling or lump in an armpit. How is breast cancer diagnosed? Initial assessment: A doctor examines the breasts and armpits. They may do tests such as a mammography, a special x-ray of the breast tissue which can indicate the possibility of tumours. Biopsy: A biopsy is when a small sample of tissue is removed from a part of the body. The sample is then examined under a microscope to look for abnormal cells. The sample can confirm or rule out cancer. If you are confirmed to have breast cancer, further tests may be needed to assess if it has spread. For example, blood tests, an ultrasound scan of the liver or a chest X-ray. Treatment options which may be considered include surgery, chemotherapy, radiotherapy and hormone treatment. Often a combination of two or more of these treatments are used. Surgery: Breast-conserving surgery or the removal of the affected breast depending on the size of the tumour. Radiotherapy: A treatment which uses high energy beams of radiation focused on cancerous tissue. This kills cancer cells, or stops them from multiplying. It is mainly used in addition to surgery. Chemotherapy: A treatment of cancer by using anti-cancer drugs which kill cancer cells, or stop them from multiplying. Hormone treatments: Some types of breast cancer are affected by the 'female' hormone oestrogen, which can stimulate the cancer cells to divide and multiply. Treatments which reduce the level of these hormones, or prevent them from working, are commonly used in people with breast cancer. How successful is treatment? The outlook is best in those who are diagnosed when the cancer is still small, and has not spread. Surgical removal of a tumour in an early stage may then give a good chance of cure. The routine mammography offered to women between the ages of 50 and 71 means more breast cancers are being diagnosed and treated at an early stage.
The Sun
6 days ago
- Entertainment
- The Sun
Jessie J reveals huge move as she makes big life decision amid breast cancer battle
POPSTAR Jessie J has revealed a huge life shift amid her breast cancer battle. 6 6 6 The Brit-born songstress doesn't know if she is cancer free after her mastectomy - and has spoken openly about her "delayed sadness" following her operation. Earlier this month, the Price Tag vocalist and mum of one told fans that she was creating space to be "angry and sad" and mourn the loss of her breast. Now the mum of one is upping sticks from Los Angeles and moving back to home turf. Jessie told how she was selling her US pad after a decade in an emotional video-post on Instagram. She uploaded a video showing her running in California's Fryman Canyon last month and revealed to fans in the caption: "June 1st - I flew to LA for just under 48 hours. "This quick trip was for a little work but also to say goodbye to my LA house (that had just sold) which was my home for just over a decade. "This hike was my and will always be one of my favourite places in studio city. "So grateful I got to have so many happy years in LA, and to visit quickly before my surgery and see some of my favourite people and make memories like this." She then added the hashtag "#livingmybestlife." Her property sale comes after The Sun exclusively r evealed the chart star's new telly role. Jessie J 'crying happy tears' as she reveals cancer update and sweet video of her son The former The Voice judge will be a guest performer on the new series of Strictly Come Dancing later this year. TOUGH JOURNEY Jessie revealed she had been diagnosed with breast cancer in June with a hugely emotional statement. Incredibly, she went ahead and performed at this year's Capital Summertime Ball in London on June 15. Jessie held back tears as she told the crowd at Wembley Stadium that she was taking a break to "beat breast cancer". Jessie J's cancer diagnosis statement in full THE singer took to social media with a candid video where she revealed her news. She said: "Before No Secrets came out, I was diagnosed with early breast cancer. I'm highlighting the word early. "Cancer sucks in any form, but I'm holding on to the word early I have been in and out of tests throughout this whole period, I just wanted to be open and share it, one because selfishly, I do not talk about it enough. "I'm not processing it because I'm working so hard. I also know how much sharing in the past has helped me with other people giving me their love and support and also their own stories. I'm an open book. "It breaks my heart that so many people are going through so much similar and worse, that's the bit that kills me. "I just want to and just let you guys know it wasn't something I'd planned. But yeah, I'm getting to keep my nipples. That's good. "It's a weird topic and a weird situation, and I know that the press are going to say crazy stuff, but you know, what to get diagnosed with this as I'm putting out a song called No Secret s right before, a song called Living My Best Life. "Which was all pre planned before I found out about this. I mean, you can't make it up. It's a very dramatic way to get a boob job. "I am going to disappear for a bit after summertime ball to have my surgery, and I will come back with massive t**s and more music." Jessie was then left in tears in a heartbreaking video taken straight after her surgery. Jessie also recently clarified she was not "cancer free" after some fans misinterpreted her comments. Last week, she made a heartbreaking admission as she marked her month milestone since her operation. Again taking to social media, she revealed "some days are hard", and that she missed being able to "pick up" her son Sky. Jessie wrote: "It will be 4 weeks since my breast cancer surgery on Saturday. I am feeling good. "Some days are harder than others." 6 6 6
